Making sense of latent TGFbeta activation, Journal of Cell Science, vol.116, issue.2, pp.217-224, 2003. ,
DOI : 10.1242/jcs.00229
EMT or EMT-Promoting Transcription Factors, Where to Focus the Light?, Frontiers in Oncology, vol.28, p.353, 2014. ,
DOI : 10.1128/MCB.02061-07
Selective Events in the Metastatic Process Defined by Analysis of the Sequential Dissemination of Subpopulations of a Mouse Mammary Tumor, Cancer research, vol.52, pp.1399-1405, 1992. ,
Prediction of Recurrence and Survival for Triple-Negative Breast Cancer (TNBC) by a Protein Signature in Tissue Samples, Molecular & Cellular Proteomics, vol.240, issue.4, pp.2936-2946, 2015. ,
DOI : 10.1158/1055-9965.EPI-09-0456
Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway, Cancer Cell, vol.21, issue.1, pp.66-81, 2012. ,
DOI : 10.1016/j.ccr.2011.11.024
Thrombospondin-1 Is a Major Activator of TGF-??1 In Vivo, Cell, vol.93, issue.7, pp.1159-1170, 1998. ,
DOI : 10.1016/S0092-8674(00)81460-9
Thrombospondin-1 Triggers Cell Migration and Development of Advanced Prostate Tumors, Cancer Research, vol.71, issue.24, pp.7649-7658, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0833
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance, Nature, vol.5, issue.7579, pp.472-476, 2015. ,
DOI : 10.1038/cddis.2014.115
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662610/pdf
Human breast tumors override the antiangiogenic effect of stromal thrombospondin-1in vivo, International Journal of Cancer, vol.63, issue.5, 2005. ,
DOI : 10.1016/S0002-9440(10)65041-9
Hypoxia and the extracellular matrix: drivers of tumour metastasis, Nature Reviews Cancer, vol.18, issue.6, pp.686-691, 2014. ,
DOI : 10.1096/fj.03-0699com
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients, Breast Cancer Research and Treatment, vol.7, issue.4, pp.725-731, 2010. ,
DOI : 10.1016/S0140-6736(05)17947-1
URL : https://hal.archives-ouvertes.fr/hal-00520003
Immunological mechanisms of the antitumor effects of supplemental oxygenation, Science Translational Medicine, vol.60, issue.277, pp.277-230, 2015. ,
DOI : 10.1016/j.jcrc.2006.12.002
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway, p.44794499, 2015. ,
Thrombospondin-1 is highly expressed in desmoplastic components of invasive ductal carcinoma of the breast and associated with lymph node metastasis, The Journal of Medical Investigation, vol.60, issue.1.2, p.9196, 2013. ,
DOI : 10.2152/jmi.60.91
Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia, Cancer Cell, vol.26, issue.5, pp.605-622, 2014. ,
DOI : 10.1016/j.ccell.2014.10.006
Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma, Oncotarget, vol.5, issue.14, pp.5782-5797, 2014. ,
DOI : 10.18632/oncotarget.2164
Signals leading to apoptosis-dependent inhibition of neovascularizationby thrombospondin-1, Nature Medicine, vol.274, issue.1, pp.41-48, 2000. ,
DOI : 10.1074/jbc.274.27.19055
Tumor Vessel Normalization by Chloroquine Independent of Autophagy, Cancer Cell, vol.26, issue.2, pp.190-206, 2014. ,
DOI : 10.1016/j.ccr.2014.06.025
Bevacizumab and micrometastases, 2014. ,
Revisiting the matricellular concept, Matrix Biology, vol.37, 2014. ,
DOI : 10.1016/j.matbio.2014.07.005
Plasma thrombospondin levels in patients with gynecologic malignancies, Cancer, vol.53, issue.11, pp.2853-2858, 1994. ,
DOI : 10.7326/0003-4819-95-5-636
B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression, Proc Natl Acad Sci, vol.107, pp.10649-10654, 2010. ,
Stromal thrombospondin-1 expression is a prognostic indicator and a new marker of invasiveness in intraductal papillary-mucinous neoplasm of the pancreas, Biomedical Research, vol.31, issue.1, 2010. ,
DOI : 10.2220/biomedres.31.13
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis, Biomed Res, vol.31, pp.13-19, 2009. ,
EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung, European Journal of Cancer, vol.47, issue.17, pp.2642-2653, 2011. ,
DOI : 10.1016/j.ejca.2011.07.007
Expression of angiogenic markers in the peripheral blood of docetaxel-treated advanced breast cancer patients: A Hellenic Cooperative Oncology Group (HeCOG) study The roles of TGF[beta] in the tumour microenvironment, Oncol Rep Nat Rev Cancer, vol.27, issue.13, pp.216-224, 2012. ,
The Activation Sequence of Thrombospondin-1 Interacts with the Latency-associated Peptide to Regulate Activation of Latent Transforming Growth Factor-??, Journal of Biological Chemistry, vol.264, issue.19, pp.13586-13593, 1999. ,
DOI : 10.1016/S0092-8674(00)80545-0
Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action, Pharmaceuticals, vol.82, issue.12, pp.1241-1278, 2010. ,
DOI : 10.1016/j.bbamcr.2006.08.001
Mechanisms of thrombospondin-1mediated metastasis and angiogenesis, Semin Thromb Hemost, vol.30, pp.127-136, 2004. ,
Attenuation of proliferation and migration of retinal pericytes in the absence of thrombospondin-1, American Journal of Physiology-Cell Physiology, vol.296, issue.4, pp.724-734, 2009. ,
DOI : 10.1002/dvdy.20837
Targeted disruption of the mouse transforming growth factor-??1 gene results in multifocal inflammatory disease, Nature, vol.359, issue.6397, pp.693-699, 1992. ,
DOI : 10.1038/359693a0
Invoking the power of thrombospondins: Regulation of thrombospondins expression, Matrix Biology, vol.37, pp.69-82, 2014. ,
DOI : 10.1016/j.matbio.2014.02.001
Comparative profiling of plasma proteome from breast cancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers, Experimental and Molecular Medicine, vol.7, issue.Pt 5, pp.36-44, 2012. ,
DOI : 10.1006/jsre.1996.0219
Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains, The Journal of Cell Biology, vol.105, issue.5, pp.2409-2415, 1987. ,
DOI : 10.1083/jcb.105.5.2409
Transforming growth factor beta signaling regulates the invasiveness of normal mammary epithelial cells and the metastasis formation of tumor cells, Horm Mol Biol Clin Investig, vol.10, pp.227-239, 2012. ,
Multitargeted antiangiogenic tyrosine kinase inhibitors combined to chemotherapy in metastatic breast cancer: a systematic review and meta-analysis The effect of thrombospondin-1 on breast cancer metastasis, Eur J Clin Pharmacol Breast Cancer Res Treat, vol.70, issue.114, pp.531-538, 2009. ,
Two Faces of TGF-Beta1 in Breast Cancer, Mediators of Inflammation, vol.2, issue.2, 2014. ,
DOI : 10.1038/nchembio.500
Targeting the TGF?? signalling pathway in disease, Nature Reviews Drug Discovery, vol.298, issue.10, pp.790-811, 2012. ,
DOI : 10.1152/ajpheart.01048.2009
Vascular reactions of normal and malignant tissues in vivo. III. Vascular reactions' of mice to fibroblasts treated in vitro with methylcholanthrene, J Natl Cancer Inst, vol.11, pp.555-580, 1950. ,
Lymphangiogenesis in development and human disease, Nature, vol.36, issue.7070, pp.946-953, 2005. ,
DOI : 10.1038/ng1383
Functional studies on circulating and disseminated tumor cells in carcinoma patients, Molecular Oncology, vol.5, issue.3, pp.443-449, 2016. ,
DOI : 10.18632/oncotarget.2592
Challenges in circulating tumour cell research, Nature Reviews Cancer, vol.497, issue.9, pp.623-631, 2014. ,
DOI : 10.1038/nature12065
TGF-?? activation, The FASEB Journal, vol.23, issue.1, pp.79-89, 2009. ,
DOI : 10.1096/fj.08-114363
A Thrombin-Sensitive Protein of Human Platelet Membranes, Proceedings of the National Academy of Sciences, vol.68, issue.1, pp.240-243, 1971. ,
DOI : 10.1073/pnas.68.1.240
Doxorubicin in Combination with a Small TGF?? Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models, PLoS ONE, vol.5, issue.4, p.10365, 2010. ,
DOI : 10.1371/journal.pone.0010365.s004
Thrombospondin-1-induced Focal Adhesion Disassembly in Fibroblasts Requires Thy-1 Surface Expression, Lipid Raft Integrity, and Src Activation, Journal of Biological Chemistry, vol.147, issue.22, pp.23510-23516, 2004. ,
DOI : 10.1074/jbc.M200427200
VEGF165b, an Inhibitory Splice Variant of Vascular Endothelial Growth Factor, Is Down-Regulated in Renal Cell Carcinoma, Cancer Research, vol.62, pp.4123-4131, 2002. ,
Resistance, epigenetics and the cancer ecosystem, Nature Medicine, vol.454, issue.3, pp.288-289, 2011. ,
DOI : 10.1038/nature07056
Angiogenesis: Tumorigenesis and the angiogenic switch, Nature Reviews Cancer, vol.3, issue.6, pp.401-410, 2003. ,
DOI : 10.1038/nrc1093
Modes of resistance to anti-angiogenic therapy, Nature Reviews Cancer, vol.25, issue.8, pp.592-603, 2008. ,
DOI : 10.1016/S0002-9440(10)64083-7
Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization, Proceedings of the National Academy of Sciences, vol.235, issue.2, pp.2065-2070, 1999. ,
DOI : 10.1006/excr.1997.3681
Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta, Hepatology, vol.34, issue.Pt 3, pp.2173-2184, 2011. ,
DOI : 10.1093/nar/gkl289
Angiogenic characteristics of circulating and tumoural thrombospondin-1 in breast cancer, Int J Oncol, vol.31, pp.1127-1132, 2007. ,
Integrin, Journal of Biological Chemistry, vol.148, issue.42, pp.40679-40687, 2003. ,
DOI : 10.1074/jbc.M209288200
Prediction of Recurrence and Survival for Triple-Negative Breast Cancer (TNBC) by a Protein Signature in Tissue Samples, Molecular & Cellular Proteomics, vol.240, issue.4, pp.2936-2946, 2015. ,
DOI : 10.1158/1055-9965.EPI-09-0456
Vascular endothelial growth factor (VEGF) in cartilage neovascularization and chondrocyte differentiation: auto-paracrine role during endochondral bone formation, Journal of cell science, vol.113, pp.59-69, 2000. ,
Mechanisms of angiogenesis and arteriogenesis, Nature Medicine, vol.153, issue.4, pp.389-395, 2000. ,
DOI : 10.1016/S0002-9440(10)65654-4
Angiogenesis in life, disease and medicine, Nature, vol.Teill II, issue.7070, pp.932-936, 2005. ,
DOI : 10.1053/j.seminoncol.2004.03.034
Molecular mechanisms and clinical applications of angiogenesis, Nature, vol.464, issue.7347, pp.298-307, 2011. ,
DOI : 10.1038/nature08889
Growth modulation of mouse keratinocytes by transforming growth factors, Cancer Res, vol.48, pp.1596-1602, 1988. ,
Family history and risk of breast cancer: nurses??? health study, Breast Cancer Research and Treatment, vol.8, issue.2, pp.1097-1104, 2012. ,
DOI : 10.1001/jama.296.2.193
CD36 Mediates the In Vitro Inhibitory Effects of Thrombospondin-1 on Endothelial Cells, CD36 Mediates the In Vitro Inhibitory Effects of Thrombospondin-1 on Endothelial Cells, pp.707-717, 1997. ,
DOI : 10.1006/bbrc.1996.1813
Expression of the thrombospondin 1 fragment 167???569 in C6 glioma cells stimulates tumorigenicity despite reduced neovascularization, Oncogene, vol.23, issue.20, pp.3642-3649, 2004. ,
DOI : 10.1006/bbrc.1995.2780
Thrombospondins and tumor angiogenesis, Trends in Molecular Medicine, vol.7, issue.9, pp.401-407, 2001. ,
DOI : 10.1016/S1471-4914(01)02102-5
Tumour dormancy: findings and hypotheses from clinical research on breast cancer, Seminars in Cancer Biology, vol.11, issue.4, pp.297-306, 2001. ,
DOI : 10.1006/scbi.2001.0385
Cartilage oligomeric matrix protein (COMP) is an abundant component of tendon, FEBS Letters, vol.227, issue.2, pp.237-240, 1994. ,
DOI : 10.1038/227680a0
Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis, Cancer Cell, vol.15, issue.3, pp.232-239, 2009. ,
DOI : 10.1016/j.ccr.2009.01.021
Endothelial Cell Metabolism in Normal and Diseased Vasculature, Circulation Research, vol.116, issue.7, pp.1231-1244, 2015. ,
DOI : 10.1161/CIRCRESAHA.116.302855
VEGF-targeted therapy: mechanisms of anti-tumour activity, Nature Reviews Cancer, vol.119, issue.8, pp.579-591, 2008. ,
DOI : 10.4161/cbt.6.8.4363
The nuances of therapy, Nature, vol.25, issue.7236, pp.290-292, 2009. ,
DOI : 10.1038/458290a
pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up, Histopathology, vol.9, issue.5, pp.154-161, 2002. ,
DOI : 10.1038/bjc.1987.230
VEGF-A: a critical regulator of blood vessel growth, European cytokine network, vol.20, pp.158-163, 2009. ,
The biology of VEGF and its receptors, Nature Medicine, vol.99, issue.21, pp.669-676, 2003. ,
DOI : 10.1073/pnas.152324099
Cancer Metabolism: Cross Talk Between Signaling and O-GlcNAcylation, Methods Mol Biol, vol.1176, pp.73-88, 2014. ,
DOI : 10.1007/978-1-4939-0992-6_7
In vivo mechanisms by which tumors producing thrombospondin 1 bypass its inhibitory effects, Genes & Development, vol.15, issue.11, pp.1373-1382, 2001. ,
DOI : 10.1101/gad.193501
Thrombospondin-1 Triggers Cell Migration and Development of Advanced Prostate Tumors, Cancer Research, vol.71, issue.24, pp.7649-7658, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0833
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance, Nature, vol.5, issue.7579, pp.472-476, 2015. ,
DOI : 10.1038/cddis.2014.115
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662610/pdf
Tumor Angiogenesis: Therapeutic Implications, New England Journal of Medicine, vol.285, pp.1182-1186, 1971. ,
Human breast tumors override the antiangiogenic effect of stromal thrombospondin-1in vivo, International Journal of Cancer, vol.63, issue.5, 2005. ,
DOI : 10.1016/S0002-9440(10)65041-9
Early Loss of E-cadherin from Cell-Cell Contacts Is Involved in the Onset of Anoikis in Enterocytes, Journal of Biological Chemistry, vol.281, issue.41, pp.43061-43069, 2004. ,
DOI : 10.1038/nrc822
Mechanisms that link the oncogenic epithelial???mesenchymal transition to suppression of anoikis, Journal of Cell Science, vol.126, issue.1, pp.21-29, 2013. ,
DOI : 10.1242/jcs.120907
VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer, Nature Reviews Clinical Oncology, vol.17, issue.4, pp.229-236, 2009. ,
DOI : 10.1016/j.ijrobp.2006.10.010
Hypoxia and the extracellular matrix: drivers of tumour metastasis, Nature Reviews Cancer, vol.18, issue.6, pp.430-439, 2014. ,
DOI : 10.1096/fj.03-0699com
Neuropilin-1 is a receptor for transforming growth factor ??-1, activates its latent form, and promotes regulatory T cell activity, Journal of Leukocyte Biology, vol.17, issue.1, pp.302-310, 2008. ,
DOI : 10.1016/j.ceb.2005.01.001
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin., Proceedings of the National Academy of Sciences, vol.87, issue.17, pp.6624-6628, 1990. ,
DOI : 10.1073/pnas.87.17.6624
Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma, BJU International, vol.433, issue.6, pp.747-755, 2008. ,
DOI : 10.1016/S0002-9440(10)62506-0
Aberrant Methylation of Thrombospondin-1 and Its Association with Reduced Expression in Gastric Cardia Adenocarcinoma, Journal of Biomedicine and Biotechnology, vol.177, issue.6, 2010. ,
DOI : 10.4049/jimmunol.177.6.3534
Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer, PLoS ONE, vol.56, issue.12, p.82241, 2013. ,
DOI : 10.1371/journal.pone.0082241.s002
The Hallmarks of Cancer, Cell, vol.100, issue.1, pp.57-70, 2000. ,
DOI : 10.1016/S0092-8674(00)81683-9
Hallmarks of Cancer: The Next Generation, Cell, vol.144, issue.5, pp.646-674, 2011. ,
DOI : 10.1016/j.cell.2011.02.013
Duration of trastuzumab in patients with HER2-positive metastatic breast cancer in prolonged remission, Current Oncology, vol.23, issue.2, pp.91-95, 2016. ,
DOI : 10.3747/co.23.2743
St. Gallen 2013: Brief Preliminary Summary of the Consensus Discussion, Breast Care, vol.8, issue.2, pp.102-109, 2013. ,
DOI : 10.1159/000351193
Immunological mechanisms of the antitumor effects of supplemental oxygenation, Science Translational Medicine, vol.60, issue.277, pp.277-230, 2015. ,
DOI : 10.1016/j.jcrc.2006.12.002
An Overview of Epithelio-Mesenchymal Transformation, Cells Tissues Organs, vol.154, issue.1, pp.8-20, 1995. ,
DOI : 10.1159/000147748
Therapies using anti-angiogenic peptide mimetics of thrombospondin-1, Expert Opinion on Therapeutic Targets, vol.10, issue.2, pp.1369-1386, 2011. ,
DOI : 10.1158/1535-7163.MCT-11-0402
Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin ??1/FAK Signaling, Cancer Cell, vol.27, issue.4, pp.574-588, 2015. ,
DOI : 10.1016/j.ccell.2015.03.008
URL : https://doi.org/10.1016/j.ccell.2015.03.008
Lung cancer, The Lancet, vol.355, issue.9202, pp.479-485, 2000. ,
DOI : 10.1016/S0140-6736(00)82038-3
-Fucosylation of the Thrombospondin Type 1 Module, Journal of Biological Chemistry, vol.267, issue.9, pp.6485-6498, 2001. ,
DOI : 10.1021/bi00223a004
Thrombospondin-1 is highly expressed in desmoplastic components of invasive ductal carcinoma of the breast and associated with lymph node metastasis. The journal of medical investigation, JMI, vol.60, pp.91-96, 2013. ,
Targeted Therapy and Checkpoint Immunotherapy Combinations for the Treatment of Cancer, Trends in Immunology, vol.37, issue.7 ,
DOI : 10.1016/j.it.2016.04.010
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer, New England Journal of Medicine, vol.350, issue.23, pp.2335-2342, 2004. ,
DOI : 10.1056/NEJMoa032691
Thrombospondin-1 Mediates Smooth Muscle Cell Proliferation Induced by Interaction With Human Platelets, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.22, issue.8, pp.1286-1292, 2002. ,
DOI : 10.1161/01.ATV.0000024684.67566.45
Coagulation Facilitates Tumor Cell Spreading in the Pulmonary Vasculature during Early Metastatic Colony Formation, Cancer Research, vol.64, issue.23, pp.8613-8619, 2004. ,
DOI : 10.1158/0008-5472.CAN-04-2078
Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells, The American Journal of Pathology, vol.163, issue.4, pp.1437-1447, 2003. ,
DOI : 10.1016/S0002-9440(10)63501-8
Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1??/Akt axis in glioblastoma, Human Pathology, vol.46, issue.10 ,
DOI : 10.1016/j.humpath.2015.06.008
Inhibition of Angiogenesis by Thrombospondin-1 Is Mediated by 2 Independent Regions Within the Type 1 Repeats, Circulation, vol.100, issue.13, pp.1423-1431, 1999. ,
DOI : 10.1161/01.CIR.100.13.1423
Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies, Nature Reviews Cancer, vol.14, issue.3, pp.182-194, 2009. ,
DOI : 10.1016/S0002-9440(10)63042-8
Increasing Survival of Ischemic Tissue by Targeting CD47, Circulation Research, vol.100, issue.5, pp.712-720, 2007. ,
DOI : 10.1161/01.RES.0000259579.35787.4e
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy, Science, vol.307, issue.5706, pp.58-62, 2005. ,
DOI : 10.1126/science.1104819
Platelet glycoprotein Ib?? supports experimental lung metastasis, Proceedings of the National Academy of Sciences, vol.267, issue.18, pp.9024-9028, 2007. ,
DOI : 10.1182/blood-2006-01-011817
URL : http://www.pnas.org/content/104/21/9024.full.pdf
Thrombospondin 1 promotes an aggressive phenotype through epithelial-tomesenchymal transition in human melanoma, Oncotarget, vol.5, pp.5782-5797, 2014. ,
Antiangiogenic therapy in oncology: current status and future directions, The Lancet, vol.388, issue.10043, 2016. ,
DOI : 10.1016/S0140-6736(15)01088-0
Thrombospondin-1 and Inhibition of Tumor Growth, Korean Journal of Physical Anthropology, vol.28, issue.4, pp.175-184, 2015. ,
DOI : 10.11637/kjpa.2015.28.4.175
A multigenic program mediating breast cancer metastasis to bone, Cancer Cell, vol.3, issue.6, pp.537-549, 2003. ,
DOI : 10.1016/S1535-6108(03)00132-6
URL : https://doi.org/10.1016/s1535-6108(03)00132-6
Dormancy of Mammary Carcinoma After Mastectomy, JNCI Journal of the National Cancer Institute, vol.63, issue.1, pp.80-85, 1999. ,
DOI : 10.1002/1097-0142(19890101)63:1<188::AID-CNCR2820630130>3.0.CO;2-M
Correlation of thrombospondin-1 and transforming growth factor-beta expression with malignancy of glioma, Neuropathology, vol.3, issue.3, pp.161-169, 2000. ,
DOI : 10.1038/359845a0
Thrombospondins: from structure to therapeutics, Cellular and Molecular Life Sciences, vol.65, issue.5, pp.700-712, 2008. ,
DOI : 10.1007/s00018-007-7486-z
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752021/pdf
Possible mechanisms of acquired resistance to anti-angiogenic drugs: implications for the use of combination therapy approaches, Cancer and Metastasis Reviews, vol.20, issue.1/2, pp.79-86, 2001. ,
DOI : 10.1023/A:1013172910858
Real-time imaging reveals the single steps of brain metastasis formation, Nature Medicine, vol.44, issue.1, pp.116-122, 2010. ,
DOI : 10.4161/cc.5.16.2864
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo, Nature, vol.362, issue.6423, pp.841-844, 1993. ,
DOI : 10.1038/362841a0
Pancreatic tumors show high levels of hypoxia, International Journal of Radiation Oncology*Biology*Physics, vol.48, issue.4, pp.919-922, 2000. ,
DOI : 10.1016/S0360-3016(00)00803-8
Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.34, issue.6, pp.1187-1192, 2014. ,
DOI : 10.1161/ATVBAHA.113.302917
Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis, Cancer Cell, vol.20, issue.5, pp.576-590, 2011. ,
DOI : 10.1016/j.ccr.2011.09.009
URL : https://doi.org/10.1016/j.ccr.2011.09.009
Molecular mechanisms of epithelial???mesenchymal transition, Nature Reviews Molecular Cell Biology, vol.22, issue.3, pp.178-196, 2014. ,
DOI : 10.1016/j.ccr.2012.10.012
Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells, PLoS ONE, vol.324, issue.12, p.24807, 2011. ,
DOI : 10.1371/journal.pone.0024807.g005
Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family, The Journal of Cell Biology, vol.120, issue.4, pp.1059-1067, 1993. ,
DOI : 10.1083/jcb.120.4.1059
Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia., Journal of Clinical Investigation, vol.101, issue.5, pp.982-992, 1998. ,
DOI : 10.1172/JCI1684
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors, The Journal of Cell Biology, vol.107, issue.6, pp.2351-2361, 1988. ,
DOI : 10.1083/jcb.107.6.2351
Anti-Vascular Endothelial Growth Factor Treatment Augments Tumor Radiation Response under Normoxic or Hypoxic Conditions, Cancer Research, vol.60, pp.5565-5570, 2000. ,
Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis, Cell, vol.156, issue.3, pp.440-455, 2014. ,
DOI : 10.1016/j.cell.2013.12.039
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling, Cell, vol.139, issue.5, pp.891-906, 2009. ,
DOI : 10.1016/j.cell.2009.10.027
URL : https://doi.org/10.1016/j.cell.2009.10.027
Methylation and silencing of the Thrombospondin-1 promoter in human cancer, Oncogene, vol.18, issue.21, pp.3284-3289, 1999. ,
DOI : 10.1002/ijc.2910590209
A Phase I Clinical Trial of Thoracic Radiotherapy and Concurrent Celecoxib for Patients with Unfavorable Performance Status Inoperable, Unresectable Non?Small Cell Lung Cancer. Clinical Cancer Research, vol.11, pp.3342-3348, 2005. ,
The Warburg Effect: How Does it Benefit Cancer Cells?, Trends in Biochemical Sciences, vol.41, issue.3, pp.211-218, 2016. ,
DOI : 10.1016/j.tibs.2015.12.001
Relationship and clinical significance of TGF-beta1 expression with Treg cell infiltration in hepatocellular carcinoma, Chinese Journal of Cancer, vol.29, issue.4, pp.403-407, 2010. ,
DOI : 10.5732/cjc.009.10628
Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cgamma and increase epithelial cell migration through indirect epidermal growth factor receptor activation, 2009. ,
Tumor Evasion of the Immune System by Converting CD4+CD25- T Cells into CD4+CD25+ T Regulatory Cells: Role of Tumor-Derived TGF-??, The Journal of Immunology, vol.178, issue.5, pp.2883-2892, 2007. ,
DOI : 10.4049/jimmunol.178.5.2883
Epithelial to Mesenchymal Transition in Renal Fibrogenesis: Pathologic Significance, Molecular Mechanism, and Therapeutic Intervention, Journal of the American Society of Nephrology, vol.15, issue.1, pp.1-12, 2004. ,
DOI : 10.1097/01.ASN.0000106015.29070.E7
Epithelial???mesenchymal transition: a new target in anticancer drug discovery, Nature Reviews Drug Discovery, vol.527, issue.5, 2016. ,
DOI : 10.1038/nature16064
Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2, Blood, vol.102, issue.13, pp.4399-4406, 2003. ,
DOI : 10.1182/blood-2003-03-0893
URL : http://www.bloodjournal.org/content/bloodjournal/102/13/4399.full.pdf
Thrombospondin-1/CD47 Blockade following Ischemia-Reperfusion Injury Is Tissue Protective, Plastic and Reconstructive Surgery, vol.124, issue.6, pp.1880-1889, 2009. ,
DOI : 10.1097/PRS.0b013e3181bceec3
URL : http://europepmc.org/articles/pmc2794041?pdf=render
Imaging of angiogenesis: from microscope to clinic, Nature Medicine, vol.99, issue.suppl. 2, pp.713-725, 2003. ,
DOI : 10.1073/pnas.172398299
Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction, Frontiers in Cell and Developmental Biology, vol.6, issue.400, p.27, 2016. ,
DOI : 10.1038/nri1806
Thrombospondin and Apoptosis: Molecular Mechanisms and Use for Design of Complementation Treatments, Current Drug Targets, vol.9, issue.10, pp.851-862, 2008. ,
DOI : 10.2174/138945008785909347
EMT, CTCs and CSCs in tumor relapse and drug-resistance, Oncotarget, vol.6, issue.13, pp.10697-10711, 2015. ,
DOI : 10.18632/oncotarget.4037
Heparin-binding peptides from thrombospondins 1 and 2 contain focal adhesion-labilizing activity, Journal of Biological Chemistry, vol.268, pp.26784-26789, 1993. ,
Activation of latent TGF-?? by thrombospondin-1: mechanisms and physiology, Cytokine & Growth Factor Reviews, vol.11, issue.1-2, pp.59-69, 2000. ,
DOI : 10.1016/S1359-6101(99)00029-5
Angiogenesis in the mouse cornea, Science, vol.205, issue.4413, pp.1416-1418, 1979. ,
DOI : 10.1126/science.472760
Thrombospondin-1 Modulates Actin Filament Remodeling and Cell Motility in Mouse Mammary Tumor cells in Vitro, Discoveries (Craiova) 2, 2014. ,
DOI : 10.15190/d.2014.23
Metastasis: from dissemination to organ-specific colonization, Nature Reviews Cancer, vol.100, issue.4, pp.274-284, 2009. ,
DOI : 10.1016/S0002-9440(10)65628-3
Lysis of Tumor Cells by Natural Killer Cells in Mice Is Impeded by Platelets, Cancer Research, vol.59, pp.1295-1300, 1999. ,
B-RafV600E and thrombospondin-1 promote thyroid cancer progression, Proceedings of the National Academy of Sciences, vol.3, issue.2, pp.10649-10654, 2010. ,
DOI : 10.3181/00379727-212-44008
URL : http://www.pnas.org/content/107/23/10649.full.pdf
Stromal thrombospondin-1 expression is a prognostic indicator and a new marker of invasiveness in intraductal papillary-mucinous neoplasm of the pancreas, Biomedical Research, vol.31, issue.1, pp.13-19, 2010. ,
DOI : 10.2220/biomedres.31.13
Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor ?? in human cancer cells ??? transcriptional activation and messenger RNA stabilization, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1574, issue.1, pp.24-34, 2002. ,
DOI : 10.1016/S0167-4781(01)00345-1
Induction of CD36 and Thrombospondin-1 in Macrophages by Hypoxia-Inducible Factor 1 and Its Relevance in the Inflammatory Process, PLoS ONE, vol.23, issue.10, p.48535, 2012. ,
DOI : 10.1371/journal.pone.0048535.s001
Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1??-dependent expression of thrombospondin-1, Journal of Cellular Biochemistry, vol.17, issue.5, pp.1918-1926, 2008. ,
DOI : 10.1161/01.ATV.17.10.2107
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis, Cancer Cell, vol.15, issue.3, pp.220-231, 2009. ,
DOI : 10.1016/j.ccr.2009.01.027
Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1, Journal of Cellular Physiology, vol.278, issue.1, pp.94-103, 2009. ,
DOI : 10.1016/S0002-9440(10)64986-3
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis, Cancer Res, vol.57, pp.963-969, 1997. ,
The Activation Sequence of Thrombospondin-1 Interacts with the Latency-associated Peptide to Regulate Activation of Latent Transforming Growth Factor-??, Journal of Biological Chemistry, vol.264, issue.19, pp.13586-13593, 1999. ,
DOI : 10.1016/S0092-8674(00)80545-0
Regulation of tumor growth and metastasis by thrombospondin-1., The FASEB Journal, vol.10, issue.10, pp.1183-1191, 1996. ,
DOI : 10.1096/fasebj.10.10.8751720
Fascin overexpression correlates with positive thrombospondin-1 and syndecan-1 expressions and a more aggressive clinical course in patients with gallbladder cancer, Journal of Hepato-Biliary-Pancreatic Surgery, vol.9, issue.3, pp.315-321, 2009. ,
DOI : 10.1091/mbc.9.5.993
Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action, Pharmaceuticals, vol.82, issue.12, pp.1241-1278, 2010. ,
DOI : 10.1016/j.bbamcr.2006.08.001
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression, Proceedings of the National Academy of Sciences, vol.100, issue.3, pp.7737-7742, 2003. ,
DOI : 10.1073/pnas.0334858100
Lactate-Modulated Induction of THBS-1 Activates Transforming Growth Factor (TGF)-beta2 and Migration of Glioma Cells In Vitro, PLoS ONE, vol.17, issue.11, p.78935, 2013. ,
DOI : 10.1371/journal.pone.0078935.s003
Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up, Annals of Oncology, vol.34, issue.(Suppl 1), pp.8-30, 2015. ,
DOI : 10.1086/321805
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis, Cancer Cell, vol.7, issue.1, pp.101-111, 2005. ,
DOI : 10.1016/j.ccr.2004.11.023
RE: Estrogen Plus Progestin and Breast Cancer Incidence and Mortality in the Women's Health Initiative Observational Study, JNCI Journal of the National Cancer Institute, vol.107, issue.1, p.372, 2014. ,
DOI : 10.1007/s10549-007-9523-x
Serum Levels of Transforming Growth Factor ??1 in Patients With Breast Cancer, Archives of Surgery, vol.136, issue.8, pp.937-940, 1960. ,
DOI : 10.1001/archsurg.136.8.937
CD44+/CD24-breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis, Breast Cancer Research, vol.50, issue.5, p.59, 2006. ,
DOI : 10.1007/BF00204786
Thrombospondin 1: a multifunctional protein implicated in the regulation of tumor growth, Critical Reviews in Oncology/Hematology, vol.49, issue.3, pp.245-258, 2004. ,
DOI : 10.1016/j.critrevonc.2003.09.009
CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior, Science Signaling, vol.2, issue.72, pp.3-3, 2009. ,
DOI : 10.1126/scisignal.272re3
Anoikis resistance and tumor metastasis, Cancer Letters, vol.272, issue.2, pp.177-185, 2008. ,
DOI : 10.1016/j.canlet.2008.05.029
A Brief Overview of the WHO Classification of Breast Tumors, 4th Edition, Focusing on Issues and Updates from the 3rd Edition, Breast Care, vol.8, issue.2, pp.149-154, 2013. ,
DOI : 10.1159/000350774
Regulation of angiogenesis in the endometrium, Trends in Endocrinology & Metabolism, vol.12, issue.4, pp.147-151, 2001. ,
DOI : 10.1016/S1043-2760(01)00379-4
Durable antitumor responses to CD47 blockade require adaptive immune stimulation, Proceedings of the National Academy of Sciences, vol.158, issue.2, pp.2646-2654, 2016. ,
DOI : 10.1016/j.jim.2007.04.008
URL : http://www.pnas.org/content/113/19/E2646.full.pdf
Hypoxia upregulates aldehyde dehydrogenase isoform 1 (ALDH1) expression and induces functional stem cell characteristics in human glioblastoma cells, Brain Tumor Pathology, vol.137, issue.4, pp.247-256, 2014. ,
DOI : 10.1007/s00432-010-0955-z
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications, Proceedings of the National Academy of Sciences, vol.179, issue.1, pp.10869-10874, 2001. ,
DOI : 10.1002/(SICI)1096-9896(199605)179:1<31::AID-PATH523>3.0.CO;2-O
Update on benefit of immunotherapy and targeted therapy in melanoma: the changing landscape, Cancer management and research, vol.6, pp.279-289, 2014. ,
Invoking the power of thrombospondins: Regulation of thrombospondins expression, Matrix Biology, vol.37, pp.69-82, 2014. ,
DOI : 10.1016/j.matbio.2014.02.001
Overexpression of Thrombospondin-1 Decreases Angiogenesis and Inhibits the Growth of Human Cutaneous Squamous Cell Carcinomas, The American Journal of Pathology, vol.155, issue.2, pp.441-452, 1999. ,
DOI : 10.1016/S0002-9440(10)65140-1
Comparative profiling of plasma proteome from breast cancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers, Experimental and Molecular Medicine, vol.7, issue.Pt 5, pp.36-44, 2012. ,
DOI : 10.1006/jsre.1996.0219
Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer, Oral Oncology, vol.39, issue.7, pp.648-655, 2003. ,
DOI : 10.1016/S1368-8375(03)00049-6
Thrombospondin1 in tissue repair and fibrosis: TGF-??-dependent and independent mechanisms, Matrix Biology, vol.31, issue.3, pp.178-186, 2012. ,
DOI : 10.1016/j.matbio.2012.01.006
Mechanism of tumour vascularization in experimental lung metastases, The Journal of Pathology, vol.396, issue.3, pp.384-396, 2015. ,
DOI : 10.1007/BF00428501
Cell confluence induces switching from proliferation to migratory signaling by site-selective phosphorylation of PDGF receptors on lipid raft platforms, Cellular Signalling, vol.28, issue.2, pp.81-93, 2016. ,
DOI : 10.1016/j.cellsig.2015.11.012
Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling, Nature Reviews Molecular Cell Biology, vol.5, issue.6, pp.397-410, 2014. ,
DOI : 10.1016/S1097-2765(00)80447-5
The epigenetics of epithelial-mesenchymal plasticity in cancer, Nature Medicine, vol.63, issue.11, pp.1438-1449, 2013. ,
DOI : 10.1016/j.cell.2007.05.022
Thrombospondin-1 Is Downregulated by Anoxia and Suppresses Tumorigenicity of Human Glioblastoma Cells, The Journal of Experimental Medicine, vol.260, issue.10, pp.1789-1798, 2000. ,
DOI : 10.1083/jcb.116.1.209
In vivo hyperoxia induces hypoxia-inducible factor-1?? overexpression in LNCaP tumors without affecting the tumor growth rate, The International Journal of Biochemistry & Cell Biology, vol.51, pp.65-74, 2014. ,
DOI : 10.1016/j.biocel.2014.03.019
Epithelial???mesenchymal transitions in development and pathologies, Current Opinion in Cell Biology, vol.15, issue.6, pp.740-746, 2003. ,
DOI : 10.1016/j.ceb.2003.10.006
Tumor Angiogenesis and Its Possible Role in Intravasation of Colorectal Epithelial Cells, Clinical Cancer Research, vol.7, pp.1627-1632, 2001. ,
Mechanical compression drives cancer cells toward invasive phenotype, Proceedings of the National Academy of Sciences, vol.20, issue.1, pp.911-916, 2012. ,
DOI : 10.1039/B613349E
URL : http://www.pnas.org/content/109/3/911.full.pdf
Thrombospondin-1 and neural crest cell migration. Developmental dynamics : an official publication of the, pp.312-322, 1999. ,
DOI : 10.1002/(sici)1097-0177(199904)214:4<312::aid-aja4>3.0.co;2-a
URL : http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0177(199904)214:4<312::AID-AJA4>3.0.CO;2-A/pdf
Tumor mechanics and metabolic dysfunction, Free Radical Biology and Medicine, vol.79, pp.269-280, 2015. ,
DOI : 10.1016/j.freeradbiomed.2014.11.020
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339308/pdf
Thrombospondin, a potentiator of tumor cell metastasis, Cancer Res, vol.47, pp.4130-4133, 1987. ,
A Broad Overview of Positron Emission Tomography Radiopharmaceuticals and Clinical Applications: What Is New?, Seminars in Nuclear Medicine, vol.41, issue.4, pp.246-264, 2011. ,
DOI : 10.1053/j.semnuclmed.2011.02.003
Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs, Cancer Cell, vol.21, issue.1, pp.82-91, 2012. ,
DOI : 10.1016/j.ccr.2011.11.023
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation, Science, vol.26, issue.1, pp.1029-1033, 2009. ,
DOI : 10.1038/nrc2536
Transient potential receptor channel???4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma, FEBS Journal, vol.37, issue.Suppl. 3, pp.6365-6377, 2007. ,
DOI : 10.1073/pnas.87.17.6624
A SNAIL1???SMAD3/4 transcriptional repressor complex promotes TGF-?? mediated epithelial???mesenchymal transition, Nature Cell Biology, vol.91, issue.8, pp.943-950, 2009. ,
DOI : 10.1002/(SICI)1097-0215(19990531)81:5<748::AID-IJC14>3.3.CO;2-Y
A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1, Proceedings of the National Academy of Sciences, vol.73, issue.11, pp.6343-6348, 1998. ,
DOI : 10.1002/1097-0142(19940601)73:11<2853::AID-CNCR2820731131>3.0.CO;2-9
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium???derived factor, Nature Medicine, vol.67, issue.4, pp.349-357, 2002. ,
DOI : 10.1161/01.ATV.20.2.309
Thrombospondin 3 (Thbs3), a new member of the thrombospondin gene family, J Biol Chem, vol.267, pp.12192-12196, 1992. ,
Thrombospondin-1 (TSP-1) Promotes the Invasive Properties of Human Breast Cancer, Journal of Surgical Research, vol.63, issue.1, pp.39-43, 1996. ,
DOI : 10.1006/jsre.1996.0219
The Thrombospondin Receptor CD47 (IAP) Modulates and Associates with alpha 2beta 1 Integrin in Vascular Smooth Muscle Cells, Molecular Biology of the Cell, vol.9, issue.4, pp.865-874, 1998. ,
DOI : 10.1091/mbc.9.4.865
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis., Journal of Clinical Investigation, vol.95, issue.4, 1995. ,
DOI : 10.1172/JCI117857
Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis, Cancer Research, vol.54, pp.6504-6511, 1994. ,
Transforming growth factor-??-induced epithelial???mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression, Oncogene, vol.24, issue.49, pp.6485-6498, 2010. ,
DOI : 10.1038/onc.2010.377
URL : http://www.nature.com/onc/journal/v29/n49/pdf/onc2010377a.pdf
Light microscopic immunolocation of thrombospondin in human tissues. The journal of histochemistry and cytochemistry : official journal of the, Histochemistry Society, vol.33, pp.295-302, 1985. ,
Cellular and molecular mechanisms of embryonic haemangiogenesis and lymphangiogenesis, Naturwissenschaften, vol.90, issue.10, pp.433-448, 2003. ,
DOI : 10.1007/s00114-003-0455-y
Lymphatic or Hematogenous Dissemination: How Does a Metastatic Tumor Cell Decide?, Cell Cycle, vol.5, issue.8, pp.812-817, 2006. ,
DOI : 10.4161/cc.5.8.2646
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459485/pdf
Anti-angiogenic drug discovery: lessons from the past and thoughts for the future, Expert Opinion on Drug Discovery, vol.28, issue.11, pp.723-743, 2012. ,
DOI : 10.1093/qjmed/hcr139
14-3-3?? Turns TGF-?????s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2, Cancer Cell, vol.27, issue.2, pp.177-192, 2015. ,
DOI : 10.1016/j.ccell.2014.11.025
Direct regulation of TWIST by HIF-1?? promotes metastasis, Nature Cell Biology, vol.127, issue.3, pp.295-305, 2008. ,
DOI : 10.1101/gad.13.17.2207
Methylation-associated Silencing of the Thrombospondin-1 Gene in Human Neuroblastoma, Cancer Research, vol.63, pp.6299-6310, 2003. ,
The effect of thrombospondin-1 on breast cancer metastasis, Breast Cancer Research and Treatment, vol.31, issue.Pt 4, pp.85-96, 2009. ,
DOI : 10.1091/mbc.3.2.181
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition, Science, vol.2, issue.5, pp.580-584, 2013. ,
DOI : 10.1002/emmm.201000070
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760262/pdf
Two Faces of TGF-Beta1 in Breast Cancer, Mediators of Inflammation, vol.2, issue.2, p.141747, 2014. ,
DOI : 10.1038/nchembio.500
The scientific contributions of M. Judah Folkman to cancer research, Nature Reviews Cancer, vol.10, issue.8, pp.647-654, 2008. ,
DOI : 10.1056/NEJM199101033240101
Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level, The FASEB Journal, vol.23, issue.10, pp.3368-3376, 2009. ,
DOI : 10.1096/fj.09-131649
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol, Molecular Cancer, vol.9, issue.1, p.33, 2010. ,
DOI : 10.1186/1476-4598-9-33
Mediation of lung metastasis of murine melanomas by a lung-specific endothelial cell adhesion molecule., Proceedings of the National Academy of Sciences, vol.88, issue.21, pp.9568-9572, 1991. ,
DOI : 10.1073/pnas.88.21.9568
In??Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior, Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior, pp.1046-1057, 2015. ,
DOI : 10.1016/j.cell.2015.04.042
Immunosuppressive networks in the tumour environment and their therapeutic relevance, Nature Reviews Cancer, vol.96, issue.4, pp.263-274, 2005. ,
DOI : 10.1073/pnas.96.26.15074