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Methods for hemodynamic parameters measurement using the laser speckle effect in macro and microcirculation

Abstract : The laser speckle is an interference effect that has been considered as a main drawback in the use of coherent light sources. However, for a specific set of applications, this effect can become a source of information. Among these applications there are the biomedical ones. The laser speckle has been used for decades to monitor microvascular blood flow but only now starts to be considered as a method that can also be used for macrocirculation parameters extraction. This work first aims at demonstrating that laser speckle can be used for macrocirculation assessment with good reliability, using the same technique as the one employed in microcirculation assessment. The use of the same methods could lead to a rapid inclusion of this new evaluation in the existing devices. Furthermore, one of the most important laser speckle issues, that prevents a fully quantitative analysis, is the effect of static scatterers. This type of scatterers strongly influences the speckle contrast, leading to a wrong interpretation of the data. The second objective of this work is to study the effect of statics catterers on the laser speckle correlation and contrast. Our results show that the laser speckle is an interesting phenomenon to extract hemodynamic parameters in the macrocirculation. This work also demonstrates that the laser speckle correlation is able to estimate the ratio between static/dynamic scatterers with good reliability. Moreover, the temporal speckle contrast achieved a very good performance in discerning dynamic scatterers with different velocities.
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Submitted on : Wednesday, January 24, 2018 - 9:29:06 AM
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  • HAL Id : tel-01691519, version 1


Pedrono Guilherme Vaz. Methods for hemodynamic parameters measurement using the laser speckle effect in macro and microcirculation. Signal and Image processing. Université d'Angers, 2016. English. ⟨NNT : 2016ANGE0041⟩. ⟨tel-01691519⟩



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