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Déterminants entomologiques de la transmission du paludisme dans la zone transfrontalière entre la Thaïlande et le Myanmar dans un contexte d'élimination de Plasmodium falciparum

Abstract : The Thai-Myanmar border is an area of low, seasonal and unstable malaria transmission. Consequently, the infection is symptomatic in all age groups and malaria morbidity and mortality is high especially in pregnant women and children.Antimalarial drug resistances in Plasmodium falciparum constitute the main obstacle to tackle malaria in this area. In the absence of alternative antimalarial drugs, the development of artemisinin resistance in Plasmodium falciparum is a major threat to global public health as it could impair the important yet labile progress made to reduce malaria endemicity (on the TMB, malaria incidence drastically decrease from 2 cases / person / year in 1980 to 0.1 cases / person / year after 2010. The primary objective of this work is to evaluate the impact of antimalarial-based elimination strategy relying on universal coverage with early diagnosis and treatment and elimination of malaria transmission hotspots (villages were the prevalence of asymptomatic infection, usually submicroscopic)with mass drig administration. Secondary objectives aim at describing and understanding the modalities and dynamic of malaria transmission in the studied area.
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Submitted on : Monday, January 15, 2018 - 12:41:07 PM
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Victor Chaumeau. Déterminants entomologiques de la transmission du paludisme dans la zone transfrontalière entre la Thaïlande et le Myanmar dans un contexte d'élimination de Plasmodium falciparum. Médecine humaine et pathologie. Université Montpellier, 2017. Français. ⟨NNT : 2017MONTT047⟩. ⟨tel-01684277⟩

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