123 1. Diagnostic des causes d'activation immunitaire, p.123 ,
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor, Science, vol.272, issue.5263, pp.872-877, 1996. ,
DOI : 10.1126/science.272.5263.872
Plasma membrane signaling in HIV-1 infection, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1838, issue.4, pp.1132-1142, 2014. ,
DOI : 10.1016/j.bbamem.2013.06.020
Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection, Proc. Natl. Acad ,
Allosteric Modulators of GABAB Receptors: Mechanism of Action and Therapeutic Perspective, Current Neuropharmacology, vol.5, issue.3, pp.195-201, 2007. ,
DOI : 10.2174/157015907781695919
G-Protein Signaling Triggered by R5 Human Immunodeficiency Virus Type 1 Increases Virus Replication Efficiency in Primary T Lymphocytes, Journal of Virology, vol.79, issue.12, pp.7938-7941, 2005. ,
DOI : 10.1128/JVI.79.12.7938-7941.2005
One of the Immune Activation Profiles Observed in HIV-1-Infected Adults with Suppressed Viremia Is Linked to Metabolic Syndrome: The ACTIVIH Study, [EBioMedicine, vol.8, 2016. ,
The Two Human CXCR4 Isoforms Display Different HIV Receptor Activities: Consequences for the Emergence of X4 Strains, The Journal of Immunology, vol.193, issue.8, p.418894, 1950. ,
DOI : 10.4049/jimmunol.1303298
URL : https://hal.archives-ouvertes.fr/hal-01074809
Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens, Journal of Virology, vol.78, issue.5, pp.2454-59, 2004. ,
DOI : 10.1128/JVI.78.5.2454-2459.2004
URL : http://jvi.asm.org/content/78/5/2454.full.pdf
CD73 Mediates Adhesion of B Cells to Follicular Dendritic Cells, Blood, vol.88, issue.5, pp.1755-64, 1996. ,
Extracellular Export of Sphingosine Kinase-1 Enzyme, Journal of Biological Chemistry, vol.269, issue.8, pp.6667-75, 2002. ,
DOI : 10.1007/978-3-0348-9006-9_18
Immunity, inflammation and cancer: a leading role for adenosine, Nature Reviews Cancer, vol.189, issue.12, pp.842-57, 2013. ,
DOI : 10.4049/jimmunol.1200744
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS), Science, vol.220, issue.4599, pp.220868-71, 1983. ,
DOI : 10.1126/science.6189183
EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5, The FASEB Journal, vol.26, issue.12, pp.4841-5412, 2012. ,
DOI : 10.1096/fj.12-208876
ENTPD1/CD39 is a promising therapeutic target in oncology, Oncogene, vol.22, issue.14, pp.1743-51, 2013. ,
DOI : 10.1002/eji.1830221031
Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation, FEBS Open Bio, vol.29, issue.1, pp.156-60, 2013. ,
DOI : 10.1038/onc.2010.173
Molecular Characterization of Oxysterol Binding to the Epstein-Barr Virus- Induced Gene 2 (GPR183), Journal of Biological Chemistry, vol.287, issue.42, pp.35470-83, 2012. ,
Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2, Journal of Biological Chemistry, vol.57, issue.33, pp.29292-302, 2011. ,
DOI : 10.1128/JVI.78.8.4108-4119.2004
AIDS-Related Cancers in the Era of Highly Active Antiretroviral Therapy, Oncology, vol.15, issue.4, pp.439-448, 2001. ,
Epstein-Barr Virus-Induced Genes: First Lymphocyte-Specific G Protein-Coupled Peptide Receptors, Journal of Virology, vol.67, issue.4, pp.2209-2220, 1993. ,
Adenosine Receptors and Inflammation, Handbook of Experimental Pharmacology, issue.193, pp.215-69, 2009. ,
DOI : 10.1007/978-3-540-89615-9_8
Differential Regulatory Effects of Adenosine on Cytokine Release by Activated Human Monocytes, Journal of Immunology, vol.153, issue.9, pp.4159-68, 1950. ,
Adenosine 5???-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation, Pharmacology & Therapeutics, vol.112, issue.2, pp.358-404, 2006. ,
DOI : 10.1016/j.pharmthera.2005.04.013
T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract, The Journal of Experimental Medicine, vol.72, issue.6, pp.749-59, 2004. ,
DOI : 10.4049/jimmunol.167.12.6711
Phospholipids: ???Greasing the wheels??? of humoral immunity, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1831, issue.3, pp.642-51, 2013. ,
DOI : 10.1016/j.bbalip.2012.09.018
Structural organization of authentic, mature HIV-1 virions and cores, The EMBO Journal, vol.22, issue.7, pp.1707-1722, 2003. ,
DOI : 10.1093/emboj/cdg143
EBI2 unlocks the door to the Tfh cell nursery, Immunology and Cell Biology, vol.8, issue.7, pp.621-643, 2016. ,
DOI : 10.1038/ni1536
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology, Pharmacology & Therapeutics, vol.115, issue.1, pp.84-105, 2007. ,
DOI : 10.1016/j.pharmthera.2007.04.006
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors, Journal of Biological Chemistry, vol.7, issue.24, pp.21453-57, 2002. ,
DOI : 10.1126/science.1070238
Oxysterols and atherosclerosis, Atherosclerosis, vol.142, issue.1, pp.1-28, 1999. ,
DOI : 10.1016/S0021-9150(98)00196-8
Interactions between endothelial cells and HIV-1, The International Journal of Biochemistry & Cell Biology, vol.33, issue.4, pp.371-90, 2001. ,
DOI : 10.1016/S1357-2725(01)00024-3
Monoclonal antibody???assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells, Human Immunology, vol.71, issue.11, pp.1073-76, 2010. ,
DOI : 10.1016/j.humimm.2010.08.010
Macrophage Inflammatory Protein-1alpha Is Induced by Human Immunodeficiency Virus Infection of Monocyte-Derived Macrophages, Blood, vol.87, issue.5, pp.2011-2030, 1996. ,
Systemic lupus erythematosus genome scan: Support for linkage at 1q23, 2q33, 16q12-13, and 17q21-23 and novel evidence at 3p24, 10q23-24, 13q32, and 18q22-23, Arthritis & Rheumatism, vol.3, issue.10, pp.3203-3213, 2004. ,
DOI : 10.1002/art.20511
Possible participation of polymorphonuclear cells stimulated by microbial immunomodulators in the dysregulated cytokine patterns of AIDS patients, Journal of Leukocyte Biology, vol.62, issue.1, pp.60-66, 1997. ,
DOI : 10.1002/jlb.62.1.60
The CD39-like Gene Family: Identification of Three New Human Members (CD39L2, CD39L3, and CD39L4), Their Murine Homologues, and a Member of the Gene Family fromDrosophila melanogaster, Genomics, vol.50, issue.3, pp.357-67, 1998. ,
DOI : 10.1006/geno.1998.5317
Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity, Journal of Autoimmunity, vol.56, pp.45-55, 2015. ,
DOI : 10.1016/j.jaut.2014.10.001
HIV Capsid Assembly, Mechanism, and Structure, Biochemistry, vol.55, issue.18, pp.2539-52, 2016. ,
DOI : 10.1021/acs.biochem.6b00159
Adenosine receptors as drug targets ??? what are the challenges?, Nature Reviews Drug Discovery, vol.122, issue.4, pp.265-86, 2013. ,
DOI : 10.1172/JCI63170
Decreased Superoxide Anion and Hydrogen Peroxide Production by Neutrophils and Monocytes in Human Immunodeficiency Virus-Infected Children and Adults, Pediatric Research, vol.34, issue.4, pp.544-50, 1993. ,
DOI : 10.1203/00006450-199310000-00032
EBI2 Is a Negative Regulator of Type I Interferons in Plasmacytoid and Myeloid Dendritic Cells, PLoS ONE, vol.173, issue.12, 2013. ,
DOI : 10.1371/journal.pone.0083457.s004
FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing, Journal of Immunology, issue.10, pp.1605037-1605081, 1950. ,
Biological roles of lysophospholipid receptors revealed by genetic null mice: An update, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1781, issue.9, pp.531-570, 2008. ,
DOI : 10.1016/j.bbalip.2008.03.004
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M, Proceedings of the National Academy of Sciences, vol.184, issue.3, pp.9613-9631, 2011. ,
DOI : 10.4049/jimmunol.0901586
URL : http://www.pnas.org/content/108/23/9613.full.pdf
A Mechanistically Novel, First Oral Therapy for Multiple Sclerosis: The Development of Fingolimod (FTY720, Gilenya), Discovery Medicine, vol.12, issue.64, pp.213-241, 2011. ,
Isolation of a new human retrovirus from West African patients with AIDS, Science, vol.233, issue.4761, pp.233343-233389, 1986. ,
DOI : 10.1126/science.2425430
CCR5 antagonism in HIV infection: ways, effects, and side effects, AIDS, vol.23, issue.15, pp.1931-1974, 2009. ,
DOI : 10.1097/QAD.0b013e32832e71cd
URL : https://hal.archives-ouvertes.fr/hal-00429305
Gene Expression Profiling of Epstein-Barr Virus-positive and -negative Monomorphic B-cell Posttransplant Lymphoproliferative Disorders, Diagnostic Molecular Pathology, vol.16, issue.3, pp.158-68, 2007. ,
DOI : 10.1097/PDM.0b013e31804f54a9
The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively., Journal of Clinical Investigation, vol.85, issue.4, pp.1150-57, 1990. ,
DOI : 10.1172/JCI114547
Neutrophil Adherence to Endothelium Is Enhanced via Adenosine A1 Receptors and Inhibited via Adenosine A2 Receptors, Journal of Immunology, issue.7, pp.1482201-1482207, 1950. ,
Adenosine promotes alternative macrophage activation via A2A and A2B receptors, The FASEB Journal, vol.26, issue.1, pp.376-8611, 2012. ,
DOI : 10.1096/fj.11-190934
CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS, Annual Review of Immunology, vol.23, issue.1, pp.127-59, 2005. ,
DOI : 10.1146/annurev.immunol.23.021704.115628
Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs, Annual Review of Immunology, vol.30, issue.1, pp.69-94, 2012. ,
DOI : 10.1146/annurev-immunol-020711-075011
adenosine receptors during reperfusion: inhibition of chemokine induction, American Journal of Physiology-Gastrointestinal and Liver Physiology, vol.286, issue.2, pp.285-293, 2003. ,
DOI : 10.1074/jbc.M211707200
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression, The Journal of Experimental Medicine, vol.261, issue.6, pp.1257-65, 2007. ,
DOI : 10.1074/jbc.275.3.2057
Hypoxia-Induced Inhibition of Adenosine Kinase Potentiates Cardiac Adenosine Release, Circulation Research, vol.81, issue.2, pp.154-64, 1997. ,
DOI : 10.1161/01.RES.81.2.154
HIV Infection, Inflammation, Immunosenescence, and Aging, Annual Review of Medicine, vol.62, issue.1, pp.141-55, 2011. ,
DOI : 10.1146/annurev-med-042909-093756
HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity, BMJ, vol.338, issue.jan26 2, p.3172, 2009. ,
DOI : 10.1136/bmj.a3172
Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide, Journal of Lipid Research, vol.78, issue.11, pp.2258-64, 2009. ,
DOI : 10.1016/S1097-2765(03)00384-8
Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue, Cell, vol.143, issue.5, pp.789-801, 2010. ,
DOI : 10.1016/j.cell.2010.11.001
The Two Human CXCR4 Isoforms Display Different HIV Receptor Activities: Consequences for the Emergence of X4 Strains, The Journal of Immunology, vol.193, issue.8, pp.4188-94, 1950. ,
DOI : 10.4049/jimmunol.1303298
URL : https://hal.archives-ouvertes.fr/hal-01074809
CD8 T Cells and Aging, CD8 T Cells and Aging, pp.45-64, 2003. ,
DOI : 10.1615/CritRevImmunol.v23.i12.30
Aging and Infectious Diseases: Workshop on HIV Infection and Aging: What Is Known and Future Research Directions, Clinical Infectious Diseases, vol.47, issue.4, pp.542-53, 2008. ,
DOI : 10.1086/590150
On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment, Experimental Cell Research, vol.319, issue.12, pp.1828-1866, 2013. ,
DOI : 10.1016/j.yexcr.2013.03.025
Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes., Journal of Clinical Investigation, vol.86, issue.1, pp.148-59, 1990. ,
DOI : 10.1172/JCI114678
Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo, Blood, vol.105, issue.12, pp.4707-4721, 2005. ,
DOI : 10.1182/blood-2004-04-1407
Adenosine???dopamine receptor???receptor interactions as an integrative mechanism in the basal ganglia, Trends in Neurosciences, vol.20, issue.10, pp.482-87, 1997. ,
DOI : 10.1016/S0166-2236(97)01096-5
CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis, Viruses, vol.3, issue.12, pp.586-612, 2011. ,
DOI : 10.3390/v3050586
Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis, Science Translational Medicine, vol.63, issue.8, pp.146-108, 2012. ,
DOI : 10.1002/art.30418
Pharmacological Analysis of Calcium Responses Mediated by the Human A3 Adenosine Receptor in Monocyte-Derived Dendritic Cells and Recombinant Cells, Molecular Pharmacology, vol.63, issue.2, pp.342-50, 2003. ,
DOI : 10.1124/mol.63.2.342
Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat, European Journal of Pharmacology, vol.438, issue.3, pp.183-88, 2002. ,
DOI : 10.1016/S0014-2999(02)01305-5
Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis, The FASEB Journal, vol.22, issue.2, pp.445-5407, 2008. ,
DOI : 10.1096/fj.07-8430com
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864119/pdf
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement, Journal of Clinical Investigation, vol.108, issue.5, pp.689-701, 2001. ,
DOI : 10.1172/JCI12450
B cell localization: regulation by EBI2 and its oxysterol ligand, Trends in Immunology, vol.34, issue.7, pp.336-377, 2013. ,
DOI : 10.1016/j.it.2013.01.007
Guidance of B Cells by the Orphan G Protein-Coupled Receptor EBI2 Shapes Humoral Immune Responses, Immunity, vol.31, issue.2, pp.259-69, 2009. ,
DOI : 10.1016/j.immuni.2009.06.016
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells, Nature Immunology, vol.174, issue.5, pp.446-53, 2013. ,
DOI : 10.1038/ni1100
adenosine receptors in human peripheral blood cells, British Journal of Pharmacology, vol.37, issue.Suppl, pp.2-11, 2000. ,
DOI : 10.1111/j.1476-5381.1996.tb15296.x
Identification and Characterization of Small Molecule Modulators of the Epstein???Barr Virus-Induced Gene 2 (EBI2) Receptor, Journal of Medicinal Chemistry, vol.57, issue.8, pp.3358-68, 2014. ,
DOI : 10.1021/jm4019355
Sphingosine 1-Phosphate Generated in the Endoplasmic Reticulum Membrane Activates Release of Stored Calcium, The Journal of Biological Chemistry, vol.269, issue.36, pp.22628-22663, 1994. ,
Shorter Survival in Advanced Human Immunodeficiency Virus Type 1 Infection Is More Closely Associated with T Lymphocyte Activation than with Plasma Virus Burden or Virus Chemokine Coreceptor Usage, The Journal of Infectious Diseases, vol.179, issue.4, pp.859-70, 1999. ,
DOI : 10.1086/314660
receptor agonist, in reperfused canine myocardium, American Journal of Physiology-Heart and Circulatory Physiology, vol.288, issue.4, pp.1851-1858, 2004. ,
DOI : 10.1161/01.CIR.88.2.709
Perturbation of CD4+ and CD8+ T-Cell Repertoires during Progression to AIDS and Regulation of the CD4+ Repertoire during Antiviral Therapy, Nature Medicine, vol.4, issue.2, pp.215-236, 1998. ,
The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G protein-coupled receptors, The FASEB Journal, vol.18, issue.3, pp.551-53, 2004. ,
DOI : 10.1096/fj.03-0910fje
Sphingosine 1-phosphate receptor 1 agonists: a patent review (2013-2015), Expert Opinion on Therapeutic Patents, vol.6, issue.4, pp.455-70, 2013. ,
DOI : 10.1021/cn200100h
Cutting Edge: CXCR4-Lo: Molecular Cloning and Functional Expression of a Novel Human CXCR4 Splice Variant, Journal of Immunology, vol.163, issue.5, pp.2368-72, 1950. ,
STIMULATION OF ADENOSINE A2A RECEPTOR INHIBITS LPS-INDUCED EXPRESSION OF INTERCELLULAR ADHESION MOLECULE 1 AND PRODUCTION OF TNF-?? IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS, Shock, vol.29, issue.2, pp.154-59, 2008. ,
DOI : 10.1097/shk.0b013e31812385da
Oxysterols direct immune cell migration via EBI2, Nature, vol.65, issue.7357, pp.524-551, 2011. ,
DOI : 10.1016/S0039-128X(00)00131-8
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297623/pdf
Crystal Structure of a Lipid G Protein-Coupled Receptor, Science, vol.4, issue.2, pp.851-55, 2012. ,
DOI : 10.1371/journal.pone.0004382
Adenosine inhibits IL-12 and TNF-alpha production via adenosine A2a receptor-dependent and independent mechanisms, The FASEB Journal, vol.14, issue.13, pp.2065-74, 2000. ,
DOI : 10.1096/fj.99-0508com
Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases, Nature Reviews. Drug Discovery, vol.7, issue.9, pp.759-70, 2008. ,
DOI : 10.1201/9781420005776
receptors in inflammation and injury: lessons learned from transgenic animals, Journal of Leukocyte Biology, vol.29, issue.3, pp.447-55, 2008. ,
DOI : 10.1016/j.tins.2006.09.004
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity, Cancer Immunology, Immunotherapy, vol.249, issue.1???2, pp.1405-1423, 2011. ,
DOI : 10.1016/S0022-1759(00)00329-X
A Trans-Acting Locus Regulates an Anti-Viral Expression Network and Type 1, 2010. ,
Receptors, Journal of Biological Chemistry, vol.45, issue.20, pp.18091-97, 2002. ,
DOI : 10.1016/S0014-2999(00)00627-0
URL : https://hal.archives-ouvertes.fr/hal-00122183
Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death, The FASEB Journal, vol.24, issue.8, pp.2631-4010, 2010. ,
DOI : 10.1096/fj.10-155192
Signaling and biological actions of sphingosine 1-phosphate, Pharmacological Research, vol.47, issue.5, pp.401-408, 2003. ,
DOI : 10.1016/S1043-6618(03)00046-X
Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms, Proceedings of the National Academy of Sciences, vol.174, issue.11, pp.19436-19477, 2006. ,
DOI : 10.4049/jimmunol.174.11.6571
CCR7 with S1P1 Signaling through AP-1 for Migration of Foxp3+ Regulatory T-Cells Controls Autoimmune Exocrinopathy, The American Journal of Pathology, vol.180, issue.1, pp.199-208, 2012. ,
DOI : 10.1016/j.ajpath.2011.09.027
Adenosine receptor ligands: differences with acute versus chronic treatment, Trends in Pharmacological Sciences, vol.17, issue.3, pp.108-121, 1996. ,
DOI : 10.1016/0165-6147(96)10002-X
Phosphodiesterase 4 Inhibitors Prevent Cytokine Secretion by T Lymphocytes by Inhibiting Nuclear Factor-kappaB and Nuclear Factor of Activated T Cells Activation, The Journal of Pharmacology and Experimental Therapeutics, vol.299, issue.2, pp.753-59, 2001. ,
S1P1-Selective in Vivo-Active Agonists from High-Throughput Screening: Off-the-Shelf Chemical Probes of Receptor Interactions, Signaling, and Fate, Chemistry & Biology, vol.12, issue.6, pp.703-718, 2005. ,
Host???microbe interactions have shaped the genetic architecture of inflammatory bowel disease, Nature, vol.286, issue.7422, pp.119-143, 2012. ,
DOI : 10.1074/jbc.M111.291492
Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase, Journal of Biological Chemistry, vol.27, issue.51, pp.33116-33138, 1996. ,
DOI : 10.1016/0167-5699(96)10026-8
Expression, Distribution, and Biochemistry of Human CD39 Role in Activation-Associated Homotypic Adhesion of Lymphocytes, Journal of Immunology, issue.7, pp.1462235-1462279, 1950. ,
Th17 and regulatory T cells: implications for AIDS pathogenesis, Current Opinion in HIV and AIDS, vol.5, issue.2, pp.151-57, 2010. ,
DOI : 10.1097/COH.0b013e328335c0c1
Platelet and Coagulation Defects Associated with HIV-1-Infection, Thrombosis and Haemostasis, vol.88, issue.3, pp.389-401, 2002. ,
Detection of dihydroxycholesterols in human plasma using HPLC???ESI-MS/MS, Steroids, vol.99, pp.131-169, 2015. ,
DOI : 10.1016/j.steroids.2015.02.002
EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues, The Journal of Immunology, vol.187, issue.6, pp.3026-3058, 2011. ,
DOI : 10.4049/jimmunol.1101262
Adenosine receptors: G protein-mediated signalling and the role of accessory proteins, Cellular Signalling, vol.14, issue.2, pp.99-108, 2002. ,
DOI : 10.1016/S0898-6568(01)00235-2
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1582, issue.1-3, pp.1-372, 2002. ,
DOI : 10.1016/S1388-1981(02)00139-7
Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner, Journal of Lipid Research, vol.10, issue.3, pp.614-635, 2006. ,
DOI : 10.1146/annurev.biochem.69.1.419
Chronic Hypoxia Enhances Adenosine Release in Rat PC12 Cells by Altering Adenosine Metabolism and Membrane Transport, Journal of Neurochemistry, vol.285, issue.2, pp.621-653, 2000. ,
DOI : 10.1042/bj2850345
Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV, The Journal of Experimental Medicine, vol.110, issue.12, pp.1731-1772, 2001. ,
DOI : 10.1002/1521-4141(200012)30:12<3598::AID-IMMU3598>3.0.CO;2-E
Adenosine Inhibits Tumor Necrosis Factor-?? Release from Mouse Peritoneal Macrophages via A2A and A2B but Not the A3 Adenosine Receptor, Journal of Pharmacology and Experimental Therapeutics, vol.317, issue.1, pp.172-80, 2006. ,
DOI : 10.1124/jpet.105.096016
receptor of human granulocytes in sepsis, Journal of Cellular and Molecular Medicine, vol.54, issue.5, pp.985-94, 2009. ,
DOI : 10.4049/jimmunol.171.8.3991
Human Endothelium as a Source of Multifunctional Cytokines: Molecular Regulation and Possible Role in Human Disease, Journal of Interferon & Cytokine Research, vol.19, issue.2, pp.91-104, 1999. ,
DOI : 10.1089/107999099314234
Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection, PLoS Medicine, vol.180, issue.10, p.203, 2008. ,
DOI : 10.1371/journal.pmed.0050203.sd002
Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome, New England Journal of Medicine, vol.309, issue.8, pp.453-58, 1983. ,
DOI : 10.1056/NEJM198308253090803
A2A Adenosine Receptor Induction Inhibits IFN-?? Production in Murine CD4+ T Cells, The Journal of Immunology, vol.174, issue.2, pp.1073-80, 1950. ,
DOI : 10.4049/jimmunol.174.2.1073
Adenosine Enhances IL-10 Secretion by Human Monocytes, Journal of Immunology, issue.11, pp.1564408-1564422, 1950. ,
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation, Nature, vol.60, issue.7352, pp.521-546, 2011. ,
DOI : 10.1016/j.neuropharm.2010.07.001
Lysophosphatidic Acid Stimulates the G-protein-coupled Receptor EDG-1 as a Low Affinity Agonist, Journal of Biological Chemistry, vol.274, issue.34, pp.22105-22117, 1998. ,
DOI : 10.1126/science.7652575
Receptor as a Drug Discovery Target, Journal of Medicinal Chemistry, vol.57, issue.9, pp.3623-50, 2014. ,
DOI : 10.1021/jm4011669
Pathogenesis of Human Immunodeficiency Virus Infection, Annals of the New York Academy of Sciences, vol.61, issue.697, pp.183-289, 1993. ,
DOI : 10.1126/science.3039662
Circulating Monocytes Are Reduced by Sphingosine-1-Phosphate Receptor Modulators Independently of S1P3, The Journal of Immunology, vol.190, issue.7, pp.3533-3573, 1950. ,
DOI : 10.4049/jimmunol.1201810
EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells, Nature, vol.1291, issue.7601, pp.110-124, 2016. ,
DOI : 10.1007/978-1-4939-2498-1_1
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation, Blood, vol.112, issue.13, pp.5084-94, 2008. ,
DOI : 10.1182/blood-2008-05-156646
Nonlinear partial differential equations and applications: Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection, Proceedings of the National Academy of Sciences, vol.74, issue.18, pp.15590-95, 2002. ,
DOI : 10.1128/JVI.74.18.8767-8770.2000
Ligand-induced Trafficking of the Sphingosine-1-phosphate Receptor EDG-1, Molecular Biology of the Cell, vol.10, issue.4, pp.1179-90, 1999. ,
DOI : 10.1091/mbc.10.4.1179
Oxysterols direct B-cell migration through EBI2, Nature, vol.408, issue.7357, pp.519-542, 2011. ,
DOI : 10.1016/j.ab.2010.09.031
Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol, Immunity, vol.38, issue.1, pp.92-105, 2013. ,
DOI : 10.1016/j.immuni.2012.11.005
Edg-1, the G protein???coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation, Journal of Clinical Investigation, vol.106, issue.8, pp.951-61, 2000. ,
DOI : 10.1172/JCI10905
Identification of Novel Genes Regulated by IL-12, IL-4, or TGF-Beta during the Early Polarization of CD4+ Lymphocytes, Journal of Immunology, issue.10, pp.1715328-1715364, 1950. ,
Sphingosine-1-phosphate signaling and its role in disease, Trends in Cell Biology, vol.22, issue.1, pp.50-60, 2012. ,
DOI : 10.1016/j.tcb.2011.09.003
Adenosine suppresses activation of nuclear factor-??B selectively induced by tumor necrosis factor in different cell types, Oncogene, vol.22, issue.8, pp.1206-1224, 2003. ,
DOI : 10.1002/hep.510280417
Sphingosine-1-Phosphate Phosphatases, Prostaglandins & Other Lipid Mediators, vol.64, issue.1-4, pp.1-4143, 2001. ,
DOI : 10.1016/S0090-6980(01)00111-3
Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists, Science, vol.296, issue.5566, pp.346-395, 2002. ,
DOI : 10.1126/science.1070238
High adenosine plasma concentration as a prognostic index for outcome in patients with septic shock, Critical Care Medicine, vol.28, issue.9, pp.3198-3202, 2000. ,
DOI : 10.1097/00003246-200009000-00014
Interleukin-15 Enhances Neutrophil Functional Activity in Patients with Human Immunodeficiency Virus Infection, Blood, vol.96, issue.5, pp.1979-84, 2000. ,
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1, Nature, vol.416, issue.6972, pp.355-60, 2004. ,
DOI : 10.1038/416094a
Adenosine A(2A) Receptor Stimulation Reduces Inflammation and Neointimal Growth in a Murine Carotid Ligation Model, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.21, issue.5, pp.791-96, 2001. ,
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells, Proceedings of the National Academy of Sciences, vol.42, issue.18, pp.16394-99, 2006. ,
DOI : 10.1021/bi027347u
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals, The Journal of Experimental Medicine, vol.70, issue.8, pp.1797-1805, 2008. ,
DOI : 10.1128/JVI.79.17.11214-11224.2005
Decreased Survival of B Cells of HIV-viremic Patients Mediated by Altered Expression of Receptors of the TNF Superfamily, The Journal of Experimental Medicine, vol.101, issue.5, pp.587-99, 2004. ,
DOI : 10.1016/S0046-8177(88)80320-4
HIV Cell-to-Cell Transmission Requires the Production of Infectious Virus Particles and Does Not Proceed through Env-Mediated Fusion Pores, Journal of Virology, vol.86, issue.7, pp.3924-3306478, 2012. ,
DOI : 10.1128/JVI.06478-11
URL : https://hal.archives-ouvertes.fr/pasteur-01372484
An A2Aadenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models, BMC Infectious Diseases, vol.70, issue.1, p.141, 2008. ,
DOI : 10.1128/IAI.70.8.4441-4446.2002
Cyclic AMP-mediated immune regulation ??? Overview of mechanisms of action in T cells, Cellular Signalling, vol.23, issue.6, pp.1009-1025, 2011. ,
DOI : 10.1016/j.cellsig.2010.11.018
Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees, Proceedings of the National Academy of Sciences, vol.101, issue.7, pp.14869-74, 1998. ,
DOI : 10.1172/JCI1457
Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation, Journal of Experimental Medicine, vol.172, issue.1, pp.95-103, 1990. ,
DOI : 10.1084/jem.172.1.95
adenosine receptor induction, Biochemical Journal, vol.391, issue.3, pp.575-80, 2005. ,
DOI : 10.1042/BJ20050888
The Effect of HIV Infection on Phagocytosis and Killing of Staphylococcus aureus by Human Pulmonary Alveolar Macrophages, The American Journal of the Medical Sciences, vol.299, issue.3, pp.158-63, 1990. ,
DOI : 10.1097/00000441-199003000-00003
Oxysterols: From cholesterol metabolites to key mediators, Progress in Lipid Research, vol.64, pp.152-69, 2016. ,
DOI : 10.1016/j.plipres.2016.09.002
Regulation of adenosine system at the onset of peritonitis, Nephrology Dialysis Transplantation, vol.25, issue.3, pp.931-970, 2010. ,
DOI : 10.1093/ndt/gfp542
Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adults with HIV Infection, The Journal of Infectious Diseases, vol.201, issue.12, pp.1788-95, 2010. ,
DOI : 10.1086/652749
Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review, Clinical Reviews in Allergy & Immunology, vol.101, issue.31, pp.59-78, 2016. ,
DOI : 10.1073/pnas.0404328101
B-Lymphocytes and Autoantibody Profiles in HIV Disease, Clinical Reviews in Allergy & Immunology, vol.14, issue.4, pp.367-84, 1996. ,
DOI : 10.1007/978-1-4612-3966-6_3
CD39/Adenosine Pathway Is Involved in AIDS Progression, PLoS Pathogens, vol.17, issue.7, 2011. ,
DOI : 10.1371/journal.ppat.1002110.s007
URL : https://hal.archives-ouvertes.fr/inserm-00616754
The effects of intravenous infusions of selective adenosine A1-receptor and A2-receptor agonists on myocardial reperfusion injury, American Heart Journal, vol.123, issue.2, pp.332-370, 1992. ,
DOI : 10.1016/0002-8703(92)90643-A
The A2aR adenosine receptor controls cytokine production in iNKT cells, European Journal of Immunology, vol.182, issue.3, pp.682-87, 2010. ,
DOI : 10.4049/jimmunol.171.5.2571
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage, Nature, vol.120, issue.6866, pp.916-936, 2001. ,
DOI : 10.1016/S0378-4274(01)00284-3
Mobilization, Ras-Mitogen-activated Protein Kinase Activation, and Adenylate Cyclase Inhibition, Journal of Biological Chemistry, vol.330, issue.42, pp.27104-27114, 1998. ,
DOI : 10.1042/bj3300605
adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney, American Journal of Physiology-Renal Physiology, vol.263, issue.32, pp.404-412, 1999. ,
DOI : 10.1007/BF02899687
Engagement of S1P1-degradative mechanisms leads to vascular leak in mice, Journal of Clinical Investigation, vol.121, issue.6, pp.2290-2300 ,
DOI : 10.1172/JCI45403DS1
Immunosuppressive and Anti-angiogenic Sphingosine 1-Phosphate Receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor, Journal of Biological Chemistry, vol.352, issue.12, pp.9082-89, 2007. ,
DOI : 10.1016/j.atherosclerosis.2004.08.024
Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors, Glia, vol.29, issue.7, pp.1119-1155, 2017. ,
DOI : 10.1016/j.tins.2006.07.006
Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy, Proceedings of the National Academy of Sciences, vol.188, issue.8, pp.3879-84, 2008. ,
DOI : 10.1016/j.mbs.2003.08.003
Expression and function of adenosine receptors in human dendritic cells, The FASEB Journal, vol.15, issue.11, pp.1963-70, 2001. ,
DOI : 10.1096/fj.01-0169com
Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate, Science, vol.316, issue.5822, pp.295-98, 2007. ,
DOI : 10.1126/science.1139221
Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons, Journal of Leukocyte Biology, vol.117, issue.Suppl., pp.1081-87, 2010. ,
DOI : 10.1159/000023993
Role of Cyclic AMP Response Element-Binding Protein in Cyclic AMP Inhibition of NF-kappaB-Mediated Transcription, Journal of Immunology, issue.11, pp.1595450-56, 1950. ,
EBI2 mediates B cell segregation between the outer and centre follicle, Nature, vol.316, issue.7259, 2009. ,
DOI : 10.1038/nature08226
Allosteric Modulators of GABAB Receptors: Mechanism of Action and Therapeutic Perspective, Current Neuropharmacology, vol.5, issue.3, pp.195-201, 2007. ,
DOI : 10.2174/157015907781695919
ACQUIRED IMMUNODEFICIENCY SYNDROME IN A HETEROSEXUAL POPULATION IN ZAIRE, The Lancet, vol.324, issue.8394, pp.65-69, 1984. ,
DOI : 10.1016/S0140-6736(84)90241-1
Monocyte phagolysosomal fusion in children born to human immunodeficiency virus-infected mothers, The Pediatric Infectious Disease Journal, vol.16, issue.1, pp.24-28, 1997. ,
DOI : 10.1097/00006454-199701000-00006
Transcriptional regulation and functional characterization of the oxysterol/EBI2 system in primary human macrophages, Biochemical and Biophysical Research Communications, vol.446, issue.3, pp.663-68, 2014. ,
DOI : 10.1016/j.bbrc.2014.01.069
receptor, BioEssays, vol.45, issue.9, 2017. ,
DOI : 10.1007/s10858-009-9359-2
CD39/NTPDase-1 activity and expression in normal leukocytes, Thrombosis Research, vol.121, issue.3, pp.309-326, 2007. ,
DOI : 10.1016/j.thromres.2007.04.008
Sphingosine Kinase Inhibitors and Cancer: Seeking the Golden Sword of Hercules, Cancer Research, vol.71, issue.21, pp.6576-82, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-2364
Receptors for Purines and Pyrimidines, Pharmacological Reviews, vol.50, issue.3, pp.413-92, 1998. ,
Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury, Critical Care, vol.15, issue.1, p.3, 2011. ,
DOI : 10.1186/cc9400
Inhibition of Cytokine Production and Cytotoxic Activity of Human Antimelanoma Specific CD8+ and CD4+ T Lymphocytes by Adenosine-Protein Kinase A Type I Signaling, Cancer Research, vol.67, issue.12, pp.5949-56, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-4249
The Origin and Maturity of Dendritic Cells Determine the Pattern of Sphingosine 1-Phosphate Receptors Expressed and Required for Efficient Migration, The Journal of Immunology, vol.185, issue.7, pp.4072-81, 1950. ,
DOI : 10.4049/jimmunol.1000568
The alliance of sphingosine-1-phosphate and its receptors in immunity, Nature Reviews Immunology, vol.3, issue.10, pp.753-63, 2008. ,
DOI : 10.1073/pnas.0401439101
Cardiovascular Pharmacology of Purines, Clinical Science, vol.92, issue.1, pp.13-24, 1979. ,
DOI : 10.1042/cs0920013
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network, Nature Reviews Immunology, vol.173, issue.7, pp.560-70, 2005. ,
DOI : 10.4049/jimmunol.173.2.866
Molecular Pharmacological Phenotyping of EBI2, Journal of Biological Chemistry, vol.7, issue.19, pp.13199-208, 2006. ,
DOI : 10.1210/me.15.1.164
The EBI2 signalling pathway plays a role in cellular crosstalk between astrocytes and macrophages, Scientific Reports, vol.57, issue.1, 2016. ,
DOI : 10.1021/jm4019355
Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells, The Journal of Immunology, vol.187, issue.11, pp.6120-6149, 1950. ,
DOI : 10.4049/jimmunol.1101225
Host A2B Adenosine Receptors Promote Carcinoma Growth, Neoplasia, vol.10, issue.9, pp.987-95, 2008. ,
DOI : 10.1593/neo.08478
Adenosine and its receptors as therapeutic targets: An overview, Saudi Pharmaceutical Journal, vol.21, issue.3, pp.245-53, 2013. ,
DOI : 10.1016/j.jsps.2012.05.011
Fc Gamma Receptor-Mediated Functions in Neutrophils Are Modulated by Adenosine Receptor Occupancy. A1 Receptors Are Stimulatory and A2 Receptors Are Inhibitory, Journal of Immunology, issue.7, pp.1452235-1452275, 1950. ,
Multiple Mechanisms Linked to Platelet Activation Result in Lysophosphatidic Acid and Sphingosine 1-Phosphate Generation in Blood, Journal of Biological Chemistry, vol.256, issue.24, pp.21197-206, 2002. ,
DOI : 10.1074/jbc.M111092200
Stratégie Mondiale Du Secteur de La Santé Contre Le VIH 2016-2021: Vers L'élimination Du SIDA, 2016. ,
Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells, Blood, vol.103, issue.4, pp.1391-97, 1959. ,
DOI : 10.1182/blood-2003-06-1959
Monocytotropic Human Immunodeficiency Virus Type 1 (HIV-1) Variants Detectable in All Stages of HIV-1 Infection Lack T-Cell Line Tropism and Syncytium-Inducing Ability in Primary T-Cell Culture, Journal of Virology, vol.65, issue.1, pp.356-63, 1991. ,
Preanalytical stability of HIV-1 and HCV RNA: impact of storage and plasma separation from cells on blood donation testing by NAT, Transfusion Medicine, vol.42, issue.2, pp.99-106, 2011. ,
DOI : 10.1046/j.1537-2995.2002.00099.x
Selective activation of G alpha i mediated signalling of S1P3 by FTY720-phosphate, Cellular Signalling, vol.20, issue.6, pp.1125-1158, 2008. ,
DOI : 10.1016/j.cellsig.2008.01.019
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection, Blood, vol.113, issue.25, pp.6304-6318, 2009. ,
DOI : 10.1182/blood-2008-10-186601
Fingolimod Modulates Peripheral Effector and Regulatory T Cells in MS Patients, Journal of Neuroimmune Pharmacology, vol.11, issue.5, pp.1106-1119, 2013. ,
DOI : 10.1038/ni.1818
Activation of Adenosine 2A Receptors Attenuates Allograft Rejection and Alloantigen Recognition, The Journal of Immunology, vol.178, issue.7, pp.4240-4289, 1950. ,
DOI : 10.4049/jimmunol.178.7.4240
Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia???reperfusion injury, The Journal of Thoracic and Cardiovascular Surgery, vol.139, issue.2, pp.474-82, 2010. ,
DOI : 10.1016/j.jtcvs.2009.08.033
Sphingosine-1-Phosphate Agonists Increase Macrophage Homing, Lymphocyte Contacts, and Endothelial Junctional Complex Formation in Murine Lymph Nodes, The Journal of Immunology, vol.175, issue.11, pp.1757151-61, 1950. ,
DOI : 10.4049/jimmunol.175.11.7151
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and ??-actinin, The FASEB Journal, vol.19, issue.12, pp.1646-5605, 2005. ,
DOI : 10.1096/fj.05-3928com
Regulation of vascular physiology and pathology by the S1P2 receptor subtype, Cardiovascular Research, vol.82, issue.2, pp.221-249, 2009. ,
DOI : 10.1093/cvr/cvp088
Monocyte function in the acquired immune deficiency syndrome. Defective chemotaxis., Journal of Clinical Investigation, vol.74, issue.6, pp.2121-2149, 1984. ,
DOI : 10.1172/JCI111637
Adenosine Treatment Attenuates Cytokine Interleukin-6 Responses to Endotoxin Challenge in Healthy Volunteers, Shock, vol.19, issue.6, pp.503-510, 2003. ,
DOI : 10.1097/01.shk.0000051756.08171.11
The outs and the ins of sphingosine-1-phosphate in immunity, Nature Reviews Immunology, vol.53, issue.6, pp.403-418, 2011. ,
DOI : 10.1021/jm101183p
Adenosine Receptor Activation Improves Survival in Mouse Models of Endotoxemia and Sepsis, The Journal of Infectious Diseases, vol.189, issue.10, pp.1897-1904, 2004. ,
DOI : 10.1086/386311
Adenosine A2B Receptor: From Cell Biology to Human Diseases, Frontiers in Chemistry, vol.182, issue.304, 2016. ,
DOI : 10.4049/jimmunol.0900515
Ecto-5???-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia, Journal of Clinical Investigation, vol.110, issue.7, pp.993-1002, 2002. ,
DOI : 10.1172/JCI0215337
Sphingosine 1-phosphate (S1P)/S1P receptor 1 signaling regulates receptor activator of NF-??B ligand (RANKL) expression in rheumatoid arthritis, Biochemical and Biophysical Research Communications, vol.419, issue.2, pp.154-59, 2012. ,
DOI : 10.1016/j.bbrc.2012.01.103
receptor activation in small-for-size liver transplantation, Transplant International, vol.279, issue.1, pp.93-101, 2007. ,
DOI : 10.1073/pnas.93.14.7063
Roles of G-protein-coupled receptor dimerization, EMBO reports, vol.5, issue.1, pp.30-34, 2004. ,
DOI : 10.1038/sj.embor.7400052
Differential Syncytium-Inducing Capacity of Human Immunodeficiency Virus Isolates: Frequent Detection of Syncytium-Inducing Isolates in Patients with Acquired Immunodeficiency Syndrome (AIDS) and AIDS-Related Complex, Journal of Virology, vol.62, issue.6, pp.2026-2058, 1988. ,
CD14lowCD16high: A cytokine-producing monocyte subset which expands during human immunodeficiency virus infection, European Journal of Immunology, vol.93, issue.12, pp.3418-3442, 1995. ,
DOI : 10.1093/infdis/169.2.420
Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury, PLoS Biology, vol.167, issue.6, p.174, 2005. ,
DOI : 10.1371/journal.pbio.0030174.t001
Crucial Role for Ecto-5'-nucleotidase (CD73) in Vascular Leakage during Hypoxia, The Journal of Experimental Medicine, vol.200, issue.11, pp.1395-1405, 2004. ,
Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5???-nucleotidase (CD73)., Tissue Antigens, vol.26, issue.1, pp.9-19, 1990. ,
DOI : 10.1093/ajcp/91.1.18
Modulators of the Sphingosine 1-phosphate receptor 1, Bioorganic & Medicinal Chemistry Letters, vol.23, issue.23, pp.6377-89, 2013. ,
DOI : 10.1016/j.bmcl.2013.09.058
Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate, Circulation Research, vol.102, issue.6, pp.669-76, 2008. ,
DOI : 10.1161/CIRCRESAHA.107.165845
Suppression of LPS-Induced TNF-Alpha Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105, Science Signaling, vol.2, issue.75, p.28, 2009. ,
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4??T Cells, Cell Reports, vol.18, issue.5, pp.1270-84, 2017. ,
DOI : 10.1016/j.celrep.2017.01.020
The pathogenesis of HIV-1 infection, British Medical Bulletin, vol.58, issue.1, pp.61-72, 2001. ,
DOI : 10.1093/bmb/58.1.61
HIV Infection Is Associated with the Spontaneous Production of Interleukin-1 (IL-1) in Vivo and with an Abnormal Release of IL-1 Alpha in Vitro, AIDS, issue.11, pp.3695-99, 1989. ,
Families of Heterotrimeric G Proteins, Journal of Biological Chemistry, vol.30, issue.31, pp.27351-58, 1999. ,
DOI : 10.1074/jbc.273.34.22105
Metabolism and functional effects of sphingolipids in blood cells, British Journal of Haematology, vol.86, issue.2, pp.282-93, 1999. ,
DOI : 10.1074/jbc.272.8.5291
HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia, Immunology and Cell Biology, vol.106, issue.2, pp.165-71, 2010. ,
DOI : 10.1182/blood-2004-08-3228
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1783, issue.5, pp.673-94, 2008. ,
DOI : 10.1016/j.bbamcr.2008.01.024
Author response image 1 Author response, eLife, vol.37, issue.2, p.757, 2013. ,
DOI : 10.7554/eLife.00757.016
Oxysterol Gradient Generation by Lymphoid Stromal Cells Guides Activated B Cell Movement during Humoral Responses, Immunity, vol.37, issue.3, pp.535-583, 2012. ,
DOI : 10.1016/j.immuni.2012.06.015
SOCS proteins, cytokine signalling and immune regulation, Nature Reviews Immunology, vol.7, issue.6, pp.454-65, 2007. ,
DOI : 10.4049/jimmunol.175.8.5077
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells, Blood, vol.111, issue.1, pp.251-59, 2008. ,
DOI : 10.1182/blood-2007-03-081646
Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate, Gene, vol.227, issue.1, pp.89-99, 1999. ,
DOI : 10.1016/S0378-1119(98)00589-7
Identification of Structural Motifs Critical for Epstein-Barr Virus-Induced Molecule 2 Function and Homology Modeling of the Ligand Docking Site, Molecular Pharmacology, vol.82, issue.6, pp.1094-1103, 2012. ,
DOI : 10.1124/mol.112.080275
Adenosine A2a receptors induce heterologous desensitization of chemokine receptors, Blood, vol.108, issue.1, pp.38-44, 2006. ,
DOI : 10.1182/blood-2005-06-2599
Adenosine A2-receptor activation inhibits neutrophil-mediated injury to coronary endothelium, American Journal of Physiology-Heart and Circulatory Physiology, vol.271, issue.4, pp.1456-1464, 1996. ,
DOI : 10.1152/ajpheart.1996.271.4.H1456
Receptor, Journal of Medicinal Chemistry, vol.54, issue.13, pp.4312-4335, 2011. ,
DOI : 10.1021/jm2003798