Skip to Main content Skip to Navigation
Theses

Etude de la fragmentation du ¹²C pour la hadronthérapie

Abstract : During the treatment of cancerous diseases using ions such as 12C, the beam will undergo nuclear reactions with the tissues leading to the production of lighter secondary fragments. This tends to delocate a part of the dose into healthy tissues and create a mixed radiation field. In order to improve the knowledge on the projectile fragmentation, an experiment was performed by our collaboration in March 2015 with a 50 MeV/n 12C beam at GANIL. This led to the measurement of double differential cross sections in angle and energy of every isotope created by the fragmentation of carbon on targets of medical interest (C, H, O and Ca). Energy and angular distributions, as well as production rates have also been obtained for every fragment and every target. Experimental data were then compared with nuclear reaction models included in the Monte-Carlo (MC) simulation codes, GEANT4 and PHITS. Important discrepancies were observed with our data, as well as between models. These observations had already led our collaboration in creating a new MC model called SLIIPIE, specialized in intermediate energies reactions with light ions. The parameters of this model were then adjusted in order to best fit the experimental data.
Complete list of metadatas

Cited literature [111 references]  Display  Hide  Download

https://tel.archives-ouvertes.fr/tel-01717556
Contributor : Abes Star :  Contact
Submitted on : Monday, February 26, 2018 - 2:57:05 PM
Last modification on : Thursday, December 12, 2019 - 3:23:24 AM
Document(s) archivé(s) le : Monday, May 28, 2018 - 7:51:28 PM

File

2017-DIVAY-CLOVIS-VAC.pdf
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-01717556, version 1

Citation

Clovis Divay. Etude de la fragmentation du ¹²C pour la hadronthérapie. Physique [physics]. Normandie Université, 2017. Français. ⟨NNT : 2017NORMC250⟩. ⟨tel-01717556⟩

Share

Metrics

Record views

581

Files downloads

553