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Tribologie et vieillissement de prothèses totales de hanche en biocéramique, in vitro = in vivo ? Enjeux scientifique et sociétal

Abstract : The performance of the prosthetic couple (femoral head/cup) influences strongly the lifetime of a total hip prosthesis. Ceramics exhibit an excellent combination of biocompatibility, mechanical resistance and tribological properties. Zirconia toughened alumina (ZTA) composites are made of an alumina matrix and well dispersed zirconia particles. They are tailored in order to offer the best compromise of hardness, chemical stability, toughness and mechanical resistance. The prediction of the performance of such materials must take into consideration the three main sources of degradation identified for Ceramic-on-Ceramic (CoC) bearings: shocks due to micro-separation, friction and low temperature degradation (LTD). Experimental tests on a shock machine, a hip-walking simulator and in an autoclave are able to simulate in vitro each of these sources of degradation, respectively. The aim of the project is to combine these tests in order to solve better the equation in vitro = in vivo. Shocks dominate the processes of degradation with the formation of wear stripes. The tested material showed an excellent resistance to LTD. The damage induced by the standard wear test on a hip-walking simulator is negligible, which raises the question about the relevance of this test for CoC couplings. An analysis of explants confirmed the decisive role of shocks in experimental tests. Zirconia phase transformation was mechanically induced within both in vitro and in vivo wear stripes. A degradation mechanism was suggested within the stripes. The material response is partly determined by the force applied during shocks.
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Submitted on : Friday, December 15, 2017 - 3:49:45 PM
Last modification on : Friday, October 23, 2020 - 4:56:33 PM


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Armelle Perrichon. Tribologie et vieillissement de prothèses totales de hanche en biocéramique, in vitro = in vivo ? Enjeux scientifique et sociétal. Autre. Université de Lyon, 2017. Français. ⟨NNT : 2017LYSEM002⟩. ⟨tel-01665193⟩



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