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Accepted. purified by column chromatography on silica gel with pentane/diethyl ether (6:4 to 3:7) as eluent, 70%) as a colourless oil ,
The organic layer was washed with a saturated aqueous solution of sodium sulphite (2 x 30 mL), water (15 mL) and brine (15 mL) The combined organic layers were dried over sodium sulphate prior to concentration. The crude product was recrystallised from methanol to afford pure 2,3-dichloro-4-iodo pyridine (4.54 g, 16.7 mmol, 82%). 1 H NMR in accordance with the literature, The reaction mixture was allowed to reach 25 °C before being diluted with diethyl ether ,
(s, N-CH3) ppm, NMR (CDCl3, 75 MHz 136.5 (t, CIVarom, 2 JC-F = 26.6 Hz) 83%) as a colourless liquid, pp.25-145 ,
25 °C): ? = 11, NMR (CDCl3, 300 MHz80 (t, 1H, JH-F = 54.7 Hz, CHF2) ppm ,