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Évaluation de l’alimentation en épidémiologie et étude de l’évolution de l’alimentation selon l’environnement socio-économique et la survenue de cancer.

Abstract : The number of cancer survivors is increasing worldwide. Several studies have demonstrated a potential beneficial impact of healthy lifestyle factors, including the diet, on cancer survival, but only a few studies have evaluated the influence of a cancer diagnosis on the long-term evolution of the diet, taking into account the socioeconomic environment of individuals as well as cancer characteristics such as the site and stage at diagnosis. Moreover, considering that the diet is one of the main determinants of health, an increasing number of epidemiological studies aim to collect dietary data but are limited by the fact that dietary data collection is very time-consuming for participants as well as for researchers. The objective of this project was 1) to better characterize the complex relations between diet and socio-economic environment among women who had cancer and 2) to develop and validate a short tool able to quickly assess the diet in several French population subgroups, and standardize dietary data collection at a national level. We used data from over 50 000 women in the prospective E3N-EPIC cohort study and considered fruit and vegetable consumption as a proxy for overall diet quality. Compared with healthy and non-cancer women, an increase in fruit and vegetable consumption was only observed in women who had an advanced stage of breast cancer (stages II-III-IV). This increase was also only observed in certain socioeconomic groups (e.g. women with high level of education and women living in the South of France). A short food frequency questionnaire (SFFQ) was also developed, both a paper and online version, to easily and quickly assess diet. Both versions were validated in a sample of 127 patients with chronic kidney disease and a sample of 92 adults selected among the general population, respectively. Our results help to understand the complex influence of the socioeconomic environment on the evolution of the diet among patients who had cancer. Further studies are required to better understand the factors that prevent cancer survivors from the adoption of healthy dietary patterns. Dietary guidelines should adapt to the socioeconomic environment of individuals, in order to reduce socioeconomic inequities in diet and cancer. Finally, within the framework of the present study, a standardized, validated, short and modern tool has been developed to quickly assess diet in French clinical and epidemiological studies. Diet and dietary patterns will therefore be comparable between several French population subgroups.
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https://tel.archives-ouvertes.fr/tel-01661480
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Submitted on : Tuesday, December 12, 2017 - 12:31:24 AM
Last modification on : Saturday, October 24, 2020 - 3:42:45 AM

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  • HAL Id : tel-01661480, version 1

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Aurélie Affret. Évaluation de l’alimentation en épidémiologie et étude de l’évolution de l’alimentation selon l’environnement socio-économique et la survenue de cancer.. Santé publique et épidémiologie. Université Paris Saclay (COmUE), 2017. Français. ⟨NNT : 2017SACLS414⟩. ⟨tel-01661480⟩

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