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La Banque Nationale de Données Alzheimer comme outil épidémiologique : état des lieux et perspectives

Abstract : The French Alzheimer database (BNA) is part of the third French plan against Alzheimer’s disease and related disorders. The objective of this database is to collect activity data of all French memory centers in order to help health authorities to organize the care offer and to generate epidemiologic knowledge on dementia. Administrative database have advantages and drawback in terms of medical research. It can gather data related to a large population, reflects the “real life” of patients and medical practices and allows longitudinal follow-up. On this other side some specific problems exists among them validity is a real concern. The objective of this work was to assess the BNA as an epidemiologic tool. We performed quality analyses and external validity studies in this perspective and initiated a research on posterior cortical atrophy to illustrate the potential of the database for the study of rare conditions. Our work shows that quality can be increased by the setup of a more structured quality program. The BNA is currently able to reproduce known published results and is sensitive to the environment. In this work we give some recommendations to increase the value of the BNA for epidemiological research.
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Submitted on : Friday, April 14, 2017 - 12:00:21 PM
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  • HAL Id : tel-01508529, version 1



Karim Tifratène. La Banque Nationale de Données Alzheimer comme outil épidémiologique : état des lieux et perspectives. Santé publique et épidémiologie. Université de Bordeaux, 2016. Français. ⟨NNT : 2016BORD0214⟩. ⟨tel-01508529⟩



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