Skip to Main content Skip to Navigation
Theses

Évaluation et compréhension des limitations fonctionnelles dans l'artériopathie oblitérante des membres inférieurs : validation du géo-positionnement par satellites pour l’étude de la dépense énergétique lors de la marche en extérieur & étude de l’effet de la durée de récupération sur la capacité de marche

Abstract : Lower-extremity peripheral artery disease (PAD) is a non-communicable disease that is associated with atherosclerosis and that leads, in most patients, to ischemia (mismatch between blood demand and blood supply) during exercise. Exercise-induced ischemia may lead to the occurrence of pain in the lower extremities during walking, thus limitingwalking capacity. Assessing walking capacity is an important step in the management of PAD patients. Thanks to the development of activity monitors such as global positioning system (GPS), it is possible to assess walking capacity under real-life conditions with measurements performed in outdoor settings. These GPS measurements have highlighted thefact that walking capacity seems variable and is likely to be influenced by the recovery duration between two symptoms-limited walks. However, this remains to be demonstrated in standardized conditions. Moreover, methodological advances are needed to standardize and express more adequately GPS data in order to better interpret walking capacity measurements. Therefore, the aim of the present thesis was two-fold: i) to validate a method for estimating walking energy expenditure (EE) in healthy subjects in outdoor setting, and that could be used in the future in PAD patients in order to compare walking capacity results obtained in outdoor setting; ii) to determine to which extent the duration of the recovery period that follows a first symptom-limited walk influences walking capacity measured during the subsequent walk in PADpatients. Our results show that GPS allows accurate estimations of walking EE in healthy subjects in outdoor setting and with various conditions of speed and grade. Moreover, our results clearly show that recovery duration influences walking capacity in PAD patients. The logarithmic shape of the relationship supports further analyses to determine a minimum recovery duration that could maximize patients walking capacity. This could have interesting implications for the development of new exercise walking programs in PAD and/or to help patients to better manage their pain during daily life.
Document type :
Theses
Complete list of metadata

https://tel.archives-ouvertes.fr/tel-01503233
Contributor : Abes Star :  Contact
Submitted on : Thursday, April 6, 2017 - 5:38:07 PM
Last modification on : Wednesday, November 3, 2021 - 6:58:46 AM
Long-term archiving on: : Friday, July 7, 2017 - 3:30:17 PM

File

2016theseMullenheimPYpartielle...
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-01503233, version 1

Citation

Pierre-Yves de Müllenheim. Évaluation et compréhension des limitations fonctionnelles dans l'artériopathie oblitérante des membres inférieurs : validation du géo-positionnement par satellites pour l’étude de la dépense énergétique lors de la marche en extérieur & étude de l’effet de la durée de récupération sur la capacité de marche. Médecine humaine et pathologie. Université Rennes 2, 2016. Français. ⟨NNT : 2016REN20053⟩. ⟨tel-01503233⟩

Share

Metrics

Record views

999

Files downloads

2020