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Détecteur liquide multipixellisé, pour l’imagerie médicale et préclinique

Abstract : The CALIPSO project (Calorimètre Liquide Ionisation Position Scintillation Organométallique) aims to develop a very efficient and very fast 511 keV γ detector for positron emission tomography. For this we use an organometallic liquid for the detection medium, the TMBi (TriMéthylBismuth). In TMBi, the interaction of a γ photon produces optical photons and electron-ion pairs.The aim of this thesis is to measure the ionization parameters of the liquid TMBi and build an efficient charge detector and its associated electronics.In order to detect the free electrons created by the ionization in the liquid, this liquid must be highly pure (which means free of any electronegative compound which could capture electrons and reduce the signal). This has been worked on using molecular sieves.The signals to be detected are very weak (fA, fC). Thus, the test setup and detector were developed for very low noise measurements (measured noise levels below 10 fA and 200 electrons).We measured the ionization yield (or Gfi) which quantifies the charge production yield in the liquid, the electrons mobility in the TMBi and the energy resolution of the detector. These are the main parameters to validate the use of TMBi for PET imaging.Future developments include the implementation of a pixelated detector and optimization of the detector energy resolution.
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Submitted on : Friday, January 20, 2017 - 11:15:07 AM
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  • HAL Id : tel-01441819, version 1

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Xavier Mancardi. Détecteur liquide multipixellisé, pour l’imagerie médicale et préclinique. Instrumentations et Détecteurs [physics.ins-det]. Université Paris Saclay (COmUE), 2016. Français. ⟨NNT : 2016SACLS236⟩. ⟨tel-01441819⟩

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