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J. Weaver, Y. Song, E. Yang, C. Ricordi, A. Pileggi et al., Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation, Tissue Engineering Part A, vol.21, issue.15-16, pp.15-16, 2015.
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J. Siepmann and N. Peppas, Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC), Advanced Drug Delivery Reviews, vol.64, pp.163-174, 2012.
DOI : 10.1016/j.addr.2012.09.028

J. Siepmann and A. Göpferich, Mathematical modeling of bioerodible, polymeric drug delivery systems, Advanced Drug Delivery Reviews, vol.48, issue.2-3, pp.229-247, 2001.
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J. Siepmann, F. Siepmann, and A. Florence, Local controlled drug delivery to the brain: Mathematical modeling of the underlying mass transport mechanisms, International Journal of Pharmaceutics, vol.314, issue.2, pp.101-119, 2006.
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J. Siepmann and F. Siepmann, Mathematical modeling of drug dissolution, International Journal of Pharmaceutics, vol.453, issue.1, pp.12-24, 2013.
DOI : 10.1016/j.ijpharm.2013.04.044

J. Siepmann, Y. Karrout, M. Gehrke, F. Penz, and F. Siepmann, Predicting drug release from HPMC/lactose tablets, International Journal of Pharmaceutics, vol.441, issue.1-2, pp.826-834, 2013.
DOI : 10.1016/j.ijpharm.2012.12.009

J. Siepmann and F. Siepmann, Mathematical modeling of drug delivery, International Journal of Pharmaceutics, vol.364, issue.2, pp.328-371, 2008.
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S. Karami, M. Imani, and F. Farahmandghavi, A novel image analysis approach for evaluation of mixing uniformity in drug-filled silicone rubber matrix, International Journal of Pharmaceutics, vol.460, issue.1-2, pp.1-2, 2014.
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B. Snorradóttir, F. Jónsdóttir, S. Sigurdsson, F. Thorsteinsson, and M. Másson, Numerical modelling and experimental investigation of drug release from layered silicone matrix systems, European Journal of Pharmaceutical Sciences, vol.49, issue.4, pp.671-678, 2013.
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E. Kaunisto, M. Marucci, P. Borgquist, and A. Axelsson, Mechanistic modelling of drug release from polymer-coated and swelling and dissolving polymer matrix systems, International Journal of Pharmaceutics, vol.418, issue.1, pp.54-77, 2011.
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B. Semmling, S. Nagel, K. Sternberg, W. Weitschies, and A. Seidlitz, Impact of different tissue-simulating hydrogel compartments on in vitro release and distribution from drug-eluting stents, European Journal of Pharmaceutics and Biopharmaceutics, vol.87, issue.3, pp.570-578, 2014.
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P. Nemati, M. Imani, F. Farahmandghavi, H. Mirzadeh, E. Marzban-rad et al., Dexamethasone-releasing cochlear implant coatings: application of artificial neural networks for modelling of formulation parameters and drug release profile, Journal of Pharmacy and Pharmacology, vol.55, issue.8, pp.1145-1157, 2013.
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P. Nemati, M. Imani, F. Farahmandghavi, H. Mirzadeh, E. Marzban-rad et al., Artificial neural networks for bilateral prediction of formulation parameters and drug release profiles from cochlear implant coatings fabricated as porous monolithic devices based on silicone rubber, Journal of Pharmacy and Pharmacology, vol.85, issue.428, pp.624-638, 2014.
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J. Siepmann, In-silico simulations of advanced drug delivery systems: What will the future offer?, International Journal of Pharmaceutics, vol.454, issue.1, pp.512-516, 2013.
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F. Siepmann, Ear Cubes for Local Controlled Drug Delivery to the Inner Ear, Int. J, 2016.

. A. Pharm, . Gehrke, . Sircoglou, C. Vincent, J. Siepmann et al., How to adjust dexamethasone mobility in silicone matrices: A quantitative treatment. Eur, J. Pharm, 2016.

J. Siepmann, Y. Karrout, . Gehrke, . Penz, and F. Siepmann, Predicting drug release from HPMC/lactose tablets, International Journal of Pharmaceutics, vol.441, issue.1-2, pp.826-834, 2013.
DOI : 10.1016/j.ijpharm.2012.12.009

M. Gehrke, C. Vincent, J. Siepmann, and F. Siepmann, Adjustment of drug release of dexamethasone from cochlear implants, th Pharmaceutical Solid State Cluster Annual Meeting, 2013.

. Poster-presentations-gehrke, J. Verin, . Gnansia, . Tourrel, C. Vincent et al., Hybrid Ear Cubes for Controlled Dexamethasone Delivery to the Inner Ear, 10 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2016.

M. Gehrke, J. Sircoglou, . Gnansia, . Tourrel, C. Vincent et al., Ear Cubes: A New Approach for Local Controlled Drug Delivery to the Inner Ear, 10 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2016.

J. Sircoglou, . Gehrke, . Tardivel, . Siepmann, . Siepmann et al., Insitu Forming Trans-Oval-Window Implants for Controlled Drug Delivery, 2016.

F. Siepmann, Y. Karrout, . Gehrke, . Penz, and J. Siepmann, Even in the Case of Freely Water-Soluble Drugs Limited Solubility Effects can Play a Major Role in the Control of Drug Release from HPMC Tablets, AAPS Annual Meeting and Exposition, 2015.

M. Gehrke, . Sircoglou, C. Vincent, J. Siepmann, and F. Siepmann, Importance of diffusion and limited drug solubility in silicone matrices for cochlear implants, st European Conference on Pharmaceutics: Drug Delivery, 2015.

M. Gehrke, C. Vincent, J. Siepmann, and F. Siepmann, How Dexamethasone release can be adjusted from silicone matrices, st International AMPTEC Conference (Advanced Materials and Pharmaceutical Technologies), 2014.

M. Gehrke, C. Vincent, J. Siepmann, and F. Siepmann, How Dexamethasone release can be adjusted from silicone matrices. 9 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014.

M. Gehrke, C. Vincent, J. Siepmann, and F. Siepmann, How to adjust desired drug release kinetics from cochlear implants. 3 rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery, 2013.

M. Gehrke, C. Vincent, J. Siepmann, and F. Siepmann, How to adjust desired drug release kinetics from cochlear implants. Forum du Prim, 2013.

F. Siepmann, Y. Karrout, . Gehrke, . Penz, and . Siepmann, J (2013) A simple mathematical model allowing for the prediction of drug release from HPMC/lactose-based controlled release matrix tablets, AAPS Annual Meeting and Exposition

M. Gehrke, . Krenzlin, C. Vincent, . Gnansia, J. Siepmann et al., In silico simulation of cochlear implants loaded with dexamethasone. 4 ème réunion annuelle de l'ITS, 2012.

F. Siepmann, Y. Karrout, . Gehrke, . Penz, and . Siepmann, J (2012) Modeling Drug Release From RetaLac ® Tablets: Impact of Drug Solubility, AAPS Annual Meeting and Exposition

F. In-berlin and . Subject?, Controlled Release of Dexamethasone to the Inner Ear from silicone-based Implants Supervisor: F. Siepmann, C. Vincent Laboratory: INSERM U1008 Controlled Drug Delivery Systems and Biomaterials 2012 License to practice in a Pharmacy 2011 Internship at the Pharmacy Prisma-Apotheke Preparation and characterization of controlled release matrices " Supervisor: F. Siepmann, Karrout Laboratory: INSERM U1008 Controlled Drug Delivery Systems and Biomaterials 2005 -2010 Pharmaceutical studies at the Ernst-Moritz-Arndt- High School Diploma at the Oberschule an der Weide, p.ENT specialist, 1985.