M. Yáñez-mó, P. Siljander, and Z. Andreu, Biological properties of extracellular vesicles and their physiological functions, Journal of Extracellular Vesicles, vol.40, issue.1, p.27066, 2015.
DOI : 10.1080/09687860600682536

G. Raposo and W. Stoorvogel, Extracellular vesicles: Exosomes, microvesicles, and friends, The Journal of Cell Biology, vol.3, issue.4, pp.373-383, 2013.
DOI : 10.1038/nrc2543

C. Thery, M. Ostrowski, and E. Segura, Membrane vesicles as conveyors of immune responses, Nature Reviews Immunology, vol.166, issue.8, pp.581-593, 2009.
DOI : 10.1038/nri2567

E. Cocucci, G. Racchetti, and J. Meldolesi, Shedding microvesicles: artefacts no more, Trends in Cell Biology, vol.19, issue.2, pp.43-51, 2009.
DOI : 10.1016/j.tcb.2008.11.003

M. Hulsmans and P. Holvoet, MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease, Cardiovascular Research, vol.100, issue.1, pp.7-18, 2013.
DOI : 10.1093/cvr/cvt161

S. El-andaloussi, Y. Lee, and S. Lakhal-littleton, Exosome-mediated delivery of siRNA in vitro and in vivo, Nature Protocols, vol.7, issue.12, pp.2112-2126, 2012.
DOI : 10.1016/j.nano.2011.04.003

S. Mathivanan, J. H. Simpson, and R. , Exosomes: Extracellular organelles important in intercellular communication, Journal of Proteomics, vol.73, issue.10, pp.1907-1920, 2010.
DOI : 10.1016/j.jprot.2010.06.006

S. Bruno and G. Camussi, Role of mesenchymal stem cell-derived microvesicles in tissue repair, Pediatric Nephrology, vol.25, issue.Suppl 1, pp.2249-2254, 2013.
DOI : 10.1007/s00467-013-2413-z

S. Gatti, S. Bruno, and M. Deregibus, Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury, Nephrology Dialysis Transplantation, vol.26, issue.5, pp.1474-1483, 2011.
DOI : 10.1093/ndt/gfr015

A. Bobrie, M. Colombo, and G. Raposo, Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses, Traffic, vol.103, issue.12, pp.1659-1668, 2011.
DOI : 10.1111/j.1600-0854.2011.01225.x

D. Conde, I. Shrimpton, C. Thiagarajan, and P. , Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation, Blood, vol.106, issue.5, pp.1604-1611, 2005.
DOI : 10.1182/blood-2004-03-1095

J. Ratajczak, K. Miekus, and M. Kucia, Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery, Leukemia, vol.8, issue.5, pp.847-856, 2006.
DOI : 10.1038/ncb1132

G. Camussi, M. Deregibus, and S. Bruno, Exosome/ microvesicle-mediated epigenetic reprogramming of cells, Am J Cancer Res, vol.1, pp.98-110, 2011.

J. Rak and A. Guha, Extracellular vesicles - vehicles that spread cancer genes, BioEssays, vol.108, issue.6, pp.489-497, 2012.
DOI : 10.1002/bies.201100169

S. Bellingham, B. Guo, and B. Coleman, Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?, Frontiers in Physiology, vol.3, p.124, 2012.
DOI : 10.3389/fphys.2012.00124

E. Emmanouilidou, K. Melachroinou, and T. Roumeliotis, Cell-Produced ??-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival, Journal of Neuroscience, vol.30, issue.20, pp.6838-6851, 2010.
DOI : 10.1523/JNEUROSCI.5699-09.2010

L. Vella and A. Hill, Generation of Cell Lines Propagating Infectious Prions and the Isolation and Characterization of Cell-derived Exosomes, Methods Mol Biol, vol.459, pp.69-82, 2008.
DOI : 10.1007/978-1-59745-234-2_5

L. Vella, R. Sharples, and V. Lawson, Packaging of prions into exosomes is associated with a novel pathway of PrP processing, The Journal of Pathology, vol.8, issue.5, pp.582-590, 2007.
DOI : 10.1002/path.2145

M. Mack, A. Kleinschmidt, and H. Brühl, Transfert of the chemokin receptor CCR5 between cells by membrane derived microparticles: A mechanism for cellular human immunodeficiency virus infection, Nature Medicine, vol.6, issue.7, pp.769-775, 2000.
DOI : 10.1038/77498

C. Arenaccio, S. Anticoli, and F. Manfredi, Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1, Retrovirology, vol.3, issue.3, p.87, 2015.
DOI : 10.1186/s12977-015-0216-y

B. György, M. Hung, and X. Breakefield, Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions, Annual Review of Pharmacology and Toxicology, vol.55, issue.1, pp.439-464, 2015.
DOI : 10.1146/annurev-pharmtox-010814-124630

N. Bradbury, Intracellular CFTR: Localization and function, Physiol Rev, vol.79, pp.175-191, 1999.

D. Sheppard and M. Welsh, Structure and function of the CFTR chloride channel, Physiol Rev, vol.79, pp.23-45, 1999.

Y. Chow, J. Plumb, and Y. Wen, Targeting Transgene Expression to Airway Epithelia and Submucosal Glands, Prominent Sites of Human CFTR Expression, Molecular Therapy, vol.2, issue.4, pp.359-367, 2000.
DOI : 10.1006/mthe.2000.0135

Y. Guo, M. Su, and M. Mcnutt, Expression and Distribution of Cystic Fibrosis Transmembrane Conductance Regulator in Neurons of the Human Brain, Journal of Histochemistry & Cytochemistry, vol.65, issue.1, pp.1113-1120, 2009.
DOI : 10.1126/science.2475911

A. Mohamed, D. Ferguson, and F. Seibert, Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells, Biochemical Journal, vol.322, issue.1, pp.259-265, 1997.
DOI : 10.1042/bj3220259

G. Gonzalez, C. Vituret, D. Pietro, and A. , Microparticle-Mediated Transfer of the Viral Receptors CAR and CD46, and the CFTR Channel in a CHO Cell Model Confers New Functions to Target Cells, PLoS ONE, vol.3, issue.12, p.52326, 2012.
DOI : 10.1371/journal.pone.0052326.s004

O. Granio, C. Norez, A. Excoffon, and K. , Cellular Localization and Activity of Ad-Delivered GFP-CFTR in Airway Epithelial and Tracheal Cells, American Journal of Respiratory Cell and Molecular Biology, vol.37, issue.6
DOI : 10.1165/rcmb.2007-0026TE
URL : https://hal.archives-ouvertes.fr/hal-00392684

O. Granio, A. Excoffon, K. Henning, and P. , Adenovirus 5???Fiber 35 Chimeric Vector Mediates Efficient Apical Correction of the Cystic Fibrosis Transmembrane Conductance Regulator Defect in Cystic Fibrosis Primary Airway Epithelia, Human Gene Therapy, vol.21, issue.3, pp.1-19, 2010.
DOI : 10.1089/hum.2009.056
URL : https://hal.archives-ouvertes.fr/hal-00580553

D. Gruenert, M. Willems, and J. Cassiman, Established cell lines used in cystic fibrosis research, Journal of Cystic Fibrosis, vol.3, pp.191-196, 2004.
DOI : 10.1016/j.jcf.2004.05.040

B. Shen, W. Finkbeiner, and J. Wine, Calu-3: A human airway epithelial cell line that shows cAMPdependent Cl-secretion, Am J Physiol, vol.266, pp.493-501, 1994.

D. Jefferson, J. Valentich, and F. Marini, Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines

L. Pizurki, M. Morris, and M. Chanson, Cystic Fibrosis Transmembrane Conductance Regulator Does Not Affect Neutrophil Migration across Cystic Fibrosis Airway Epithelial Monolayers, The American Journal of Pathology, vol.156, issue.4, pp.1407-1416, 2000.
DOI : 10.1016/S0002-9440(10)65009-2

S. Corjon, G. Gonzalez, and P. Henning, Cell Entry and Trafficking of Human Adenovirus Bound to Blood Factor X Is Determined by the Fiber Serotype and Not Hexon:Heparan Sulfate Interaction, PLoS ONE, vol.5, issue.5, p.18205, 2011.
DOI : 10.1371/journal.pone.0018205.g011

O. Granio, M. Porcherot, and S. Corjon, Improved Adenovirus Type 5 Vector-Mediated Transduction of Resistant Cells by Piggybacking on Coxsackie B-Adenovirus Receptor-Pseudotyped Baculovirus, Journal of Virology, vol.83, issue.12, pp.6048-6066, 2009.
DOI : 10.1128/JVI.00012-09

S. Dafonseca, A. Blommaert, and P. Coric, The 3- O-(3¢,3¢-dimethylsuccinyl) derivative of betulinic acid (DSB) inhibits the assembly of virus-like particles in HIV-1 Gag precursor-expressing cells, Antiviral Ther, vol.12, pp.1185-1203, 2007.

S. Dafonseca, P. Coric, and B. Gay, The inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain, Virology Journal, vol.5, issue.1, p.162, 2008.
DOI : 10.1186/1743-422X-5-162

L. Franqueville, P. Henning, and M. Magnusson, Protein Crystals in Adenovirus Type 5-Infected Cells: Requirements for Intranuclear Crystallogenesis, Structural and Functional Analysis, PLoS ONE, vol.116, issue.8, p.2894, 2008.
DOI : 10.1371/journal.pone.0002894.g013

S. Hong, M. Magnusson, and P. Henning, Adenovirus stripping: a versatile method to generate adenovirus vectors with new cell target specificity, Molecular Therapy, vol.7, issue.5, pp.692-699, 2003.
DOI : 10.1016/S1525-0016(03)00067-4
URL : https://hal.archives-ouvertes.fr/hal-00122756

N. Ftaich, C. Ciancia, and C. Viarouge, ABSTRACT, Journal of Virology, vol.89, issue.20, pp.10467-10481, 2015.
DOI : 10.1128/JVI.01541-15

M. Chanson, I. Scerri, and S. Suter, Defective regulation of gap junctional coupling in cystic fibrosis pancreatic duct cells, Journal of Clinical Investigation, vol.103, issue.12, pp.1677-1684, 1999.
DOI : 10.1172/JCI5645

K. Long and K. Walsh, Iodide efflux measurements with an iodide-selective electrode: A non-radioactive procedure for monitoring cellular chloride transport, Methods in Cell Science, vol.19, issue.3, pp.207-212, 1997.
DOI : 10.1023/A:1009766219974

A. Aleksandrov, P. Kota, and L. Aleksandrov, Regulatory Insertion Removal Restores Maturation, Stability and Function of ??F508 CFTR, Journal of Molecular Biology, vol.401, issue.2, pp.194-210, 2010.
DOI : 10.1016/j.jmb.2010.06.019

S. Sumarheni, S. Hong, and V. Josserand, Human Full-Length Coagulation Factor X and a GLA Domain-Derived 40-mer Polypeptide Bind to Different Regions of the Adenovirus Serotype 5 Hexon Capsomer, Human Gene Therapy, vol.25, issue.4, pp.339-349, 2014.
DOI : 10.1089/hum.2013.222
URL : https://hal.archives-ouvertes.fr/hal-01100391

Y. Zhu, A. Chidekel, and T. Shaffer, Cultured human airway apithelial cells (Calu-3): A model of human respiratory function, structure, and inflammatory responses, Crit Care Res Pract, vol.2010, p.394578, 2010.

M. Kesimer, M. Scull, and B. Brighton, Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense, The FASEB Journal, vol.23, issue.6, pp.1858-1868, 2009.
DOI : 10.1096/fj.08-119131

J. Webber and A. Clayton, How pure are your vesicles?, Journal of Extracellular Vesicles, vol.7, issue.1, 2013.
DOI : 10.3402/jev.v2i0.19861

S. Conner and S. Schmid, Regulated portals of entry into the cell, Nature, vol.277, issue.6927, pp.37-44, 2003.
DOI : 10.1038/nature01451

D. Dutta and J. Donaldson, Search for inhibitors of endocytosis, Cellular Logistics, vol.113, issue.4, pp.203-208, 2012.
DOI : 10.1016/0014-4827(86)90348-4

M. West, M. Bretscher, and C. Watts, Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells [published erratum appears in J Cell Biol 1990 Mar;110(3):859], The Journal of Cell Biology, vol.109, issue.6, pp.2731-2739, 1989.
DOI : 10.1083/jcb.109.6.2731

L. Mulcahy, R. Pink, and D. Carter, Routes and mechanisms of extracellular vesicle uptake, Journal of Extracellular Vesicles, vol.25, issue.1, p.24641, 2014.
DOI : 10.3402/jev.v3.24641

M. Kanada, M. Bachmann, and J. Hardy, Differential fates of biomolecules delivered to target cells via extracellular vesicles, Proceedings of the National Academy of Sciences, vol.112, pp.1433-1442, 2015.
DOI : 10.1073/pnas.1418401112

Y. Wang, H. Su, and Y. Yang, Systemic Delivery of Modified mRNA Encoding Herpes Simplex Virus 1 Thymidine Kinase for Targeted Cancer Gene Therapy, Molecular Therapy, vol.21, issue.2, pp.358-367, 2013.
DOI : 10.1038/mt.2012.250