Systèmes intégrés pour l'hybridation vivant-artificiel : modélisation et conception d'une chaine de détection analogique adaptative

Abstract : Bioelectronics is a transdisciplinary field which develops interconnection devices between biological systems presenting electrical activity and the world of electronics. This communication with living tissues implies to observe the electrical activity of the cells and therefore requires an electronic acquisition chain.The use of Multi / Micro Electrode Array leads to systems that acquire a large numberof parallel channels, thus consumption and congestion of acquisition circuits have a significant impact on the viability of the system to be implanted.This thesis proposes two reflections about these acquisition circuits. One of these reflections relates to amplifier circuits, their input impedance and consumption; the other concerns an analogue action potentials detector, its modeling and optimization.These theoretical work leading to concrete results, an ASIC was designed, manufactured, tested and characterized in this thesis. This eight-channel ASIC therefore includes amplifiers and analogue action potentials detector and is the main contribution of this thesis.
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François Rummens. Systèmes intégrés pour l'hybridation vivant-artificiel : modélisation et conception d'une chaine de détection analogique adaptative. Sciences de l'ingénieur [physics]. Université de Bordeaux, 2015. Français. ⟨NNT : 2015BORD0431⟩. ⟨tel-01294213⟩

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