Systèmes intégrés pour l'hybridation vivant-artificiel : modélisation et conception d'une chaîne de détection analogique adaptative

Abstract : Bioelectronics is a transdisciplinary field which develops interconnection devicesbetween biological systems presenting electrical activity and the world of electronics. Thiscommunication with living tissues implies to observe the electrical activity of the cells andtherefore requires an electronic acquisition chain.The use of Multi / Micro Electrode Array leads to systems that acquire a large numberof parallel channels, thus consumption and congestion of acquisition circuits have asignificant impact on the viability of the system to be implanted.This thesis proposes two reflections about these acquisition circuits. One of thesereflections relates to amplifier circuits, their input impedance and consumption; the otherconcerns an analogue action potentials detector, its modeling and optimization.These theoretical work leading to concrete results, an ASIC was designed,manufactured, tested and characterized in this thesis. This eight-channel ASIC thereforeincludes amplifiers and analogue action potentials detector and is the main contribution of thisthesis.
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François Rummens. Systèmes intégrés pour l'hybridation vivant-artificiel : modélisation et conception d'une chaîne de détection analogique adaptative. Electronique. Université de Bordeaux, 2015. Français. ⟨NNT : 2015BORD0431⟩. ⟨tel-01266670⟩

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