Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes, International Immunology, vol.8, issue.5, pp.765-772, 1996. ,
DOI : 10.1093/intimm/8.5.765
Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia, British Journal of Haematology, vol.207, issue.3, pp.360-370, 2013. ,
DOI : 10.1111/bjh.12401
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production, International Immunology, vol.19, issue.4, pp.345-354, 2007. ,
DOI : 10.1093/intimm/dxm014
2B4 (CD244) signaling via chimeric receptors costimulates tumor-antigen specific proliferation and in vitro expansion of human T cells, Cancer Immunology, Immunotherapy, vol.178, issue.12, 1991. ,
DOI : 10.1007/s00262-009-0704-9
A chemokine-driven positive feedback loop organizes lymphoid follicles, Nature, vol.406, pp.309-314, 2000. ,
Toll-like receptor 4???dependent contribution of the immune system to anticancer chemotherapy and radiotherapy, Nature Medicine, vol.289, issue.9, pp.1050-1059, 2007. ,
DOI : 10.1038/nm1622
URL : https://hal.archives-ouvertes.fr/hal-00316924
Characterization of CD4+ CTLs Ex Vivo, The Journal of Immunology, vol.168, issue.11, pp.5954-5958, 2002. ,
DOI : 10.4049/jimmunol.168.11.5954
B cell???intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans, The Journal of Experimental Medicine, vol.19, issue.1, pp.155-171, 2010. ,
DOI : 10.1182/blood-2006-10-054973
Cyclophosphamide (Cy)-facilitated adoptive immunotherapy of a Cy-resistant tumour. Evidence that Cy permits the expression of adoptive T-cell mediated immunity by removing suppressor T cells rather than by reducing tumour burden, Immunology, vol.65, pp.87-92, 1988. ,
Tumor Cell Death and ATP Release Prime Dendritic Cells and Efficient Anticancer Immunity, Cancer Research, vol.70, issue.3, pp.855-858, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-3566
Human Peripheral Blood T Regulatory Cells (Tregs), Functionally Primed CCR4+ Tregs and Unprimed CCR4- Tregs, Regulate Effector T Cells Using FasL, The Journal of Immunology, vol.178, issue.8, pp.4891-4900, 2007. ,
DOI : 10.4049/jimmunol.178.8.4891
CD4+CD25high Regulatory Cells in Human Peripheral Blood, The Journal of Immunology, vol.167, issue.3, pp.1245-1253, 2001. ,
DOI : 10.4049/jimmunol.167.3.1245
The Association Between Treatment-Related Lymphopenia and Survival in Newly Diagnosed Patients with Resected Adenocarcinoma of the Pancreas, Cancer Investigation, vol.22, issue.8, pp.571-576, 2012. ,
DOI : 10.1016/j.ijrobp.2004.12.085
Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse, Journal of Clinical Oncology, vol.24, issue.34, pp.5373-5380, 2006. ,
DOI : 10.1200/JCO.2006.05.9584
In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, whereas Mature Dendritic Cells Are Located in Peritumoral Areas, Journal of Experimental Medicine, vol.190, issue.10, pp.1417-1426, 1999. ,
DOI : 10.1084/jem.190.10.1417
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3, Nat Genet, vol.27, pp.20-21, 2001. ,
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine, Blood, vol.106, issue.6, pp.2018-2025, 2005. ,
DOI : 10.1182/blood-2005-02-0642
Primed Antigen-Specific CD4+ T Cells Are Required for NK Cell Activation In Vivo upon Leishmania major Infection, The Journal of Immunology, vol.185, issue.4, pp.2174-2181, 2010. ,
DOI : 10.4049/jimmunol.1001486
URL : https://hal.archives-ouvertes.fr/hal-00724243
Cytotoxic T lymphocytes specific for I region determinants do not require interactions with H-2K or D gene products, Journal of Experimental Medicine, vol.145, issue.5, pp.1387-1392, 1977. ,
DOI : 10.1084/jem.145.5.1387
Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function, Immunological Reviews, vol.108, issue.1, pp.82-101, 2012. ,
DOI : 10.1111/imr.12006
Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO, The Journal of Immunology, vol.184, issue.8, pp.4317-4326, 2010. ,
DOI : 10.4049/jimmunol.0903781
Aids-related malignancies, Nature Reviews Cancer, vol.2, issue.5, pp.373-382, 2002. ,
DOI : 10.1038/nrc797
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/???B7 family, Immunological Reviews, vol.355, issue.Suppl., pp.180-205, 2011. ,
DOI : 10.1111/j.1600-065X.2011.01011.x
A Role for CD40 Expression on CD8+ T Cells in the Generation of CD8+ T Cell Memory, Science, vol.297, issue.5589, pp.2060-2063, 2002. ,
DOI : 10.1126/science.1072615
Safety and Activity of Anti???PD-L1 Antibody in Patients with Advanced Cancer, New England Journal of Medicine, vol.366, issue.26, pp.2455-2465, 2012. ,
DOI : 10.1056/NEJMoa1200694
Anti-IL-17 phase II data for psoriasis: A review, Journal of Dermatological Treatment, vol.27, issue.1, 2014. ,
DOI : 10.1007/s12016-012-8307-1
The Concept of Immunological Surveillance, Prog Exp Tumor Res, vol.13, pp.1-27, 1970. ,
DOI : 10.1159/000386035
Optimal Germinal Center Responses Require??a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84, Immunity, vol.32, issue.2, pp.253-265, 2010. ,
DOI : 10.1016/j.immuni.2010.01.010
Vaccination of a Melanoma Patient with Mature Dendritic Cells Pulsed with MAGE-3 Peptides Triggers the Activity of Nonvaccine Anti-Tumor Cells, The Journal of Immunology, vol.180, issue.5, pp.3585-3593, 2008. ,
DOI : 10.4049/jimmunol.180.5.3585
T lymphocytes with cellular maturation, The Journal of Experimental Medicine, vol.151, issue.13, pp.2865-2877, 2006. ,
DOI : 10.1016/S0145-305X(02)00039-3
Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM+IgD+CD27+ B cells harbor the virus in X-linked lymphoproliferative disease patients, Blood, vol.112, issue.3, pp.672-679, 2008. ,
DOI : 10.1182/blood-2007-10-116269
Cancer in the Transplant Recipient, Cold Spring Harbor Perspectives in Medicine, vol.3, issue.7, 2013. ,
DOI : 10.1101/cshperspect.a015677
Live-cell assay to detect antigen-specific CD4+ T-cell responses by CD154 expression, Nature Protocols, vol.172, issue.1, pp.1-6, 2006. ,
DOI : 10.1038/nprot.2006.1
Chemoimmunotherapy: reengineering tumor immunity. Cancer immunology, immunotherapy : CII 62, pp.203-216, 2013. ,
DOI : 10.1007/s00262-012-1388-0
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608094
Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients, Lung Cancer, vol.69, issue.3, pp.348-354, 2010. ,
DOI : 10.1016/j.lungcan.2009.11.013
ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6, Immunity, vol.34, issue.6, pp.932-946, 2011. ,
DOI : 10.1016/j.immuni.2011.03.023
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions, Nature Medicine, vol.176, issue.8, pp.983-988, 2011. ,
DOI : 10.1038/ng0697-161
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151340
Model Predicting Survival in Stage I Melanoma Based on Tumor Progression, JNCI Journal of the National Cancer Institute, vol.81, issue.24, pp.1893-1904, 1989. ,
DOI : 10.1093/jnci/81.24.1893
Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cellsin vitro, International Journal of Cancer, vol.269, issue.4, 2003. ,
DOI : 10.1002/ijc.10969
T cell precursor, The Journal of Experimental Medicine, vol.94, issue.8, pp.1903-1916, 2008. ,
DOI : 10.1182/blood-2004-04-1667
Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells, International Journal of Cancer, vol.67, issue.2, pp.289-297, 1992. ,
DOI : 10.1002/ijc.2910500220
Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands, Immunological Reviews, vol.88, issue.1, pp.156-170, 2006. ,
DOI : 10.1016/0092-8674(89)90844-1
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs, The Journal of Experimental Medicine, vol.206, issue.1, pp.51-59, 2009. ,
DOI : 10.1093/nar/gkl006
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival, Nature Medicine, vol.165, issue.9, pp.942-949, 2004. ,
DOI : 10.1016/S0022-1759(01)00359-3
Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin, The Journal of Experimental Medicine, vol.163, issue.4, pp.743-755, 2013. ,
DOI : 10.4049/jimmunol.0901199
Tumor emergence is sensed by selfspecific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice, The Journal of clinical investigation, vol.119, pp.2648-2662, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00420216
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression, Nature, vol.170, issue.7109, pp.350-354, 2006. ,
DOI : 10.1126/science.274.5284.94
Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer, Cancer Research, vol.71, issue.20, pp.6391-6399, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0952
Advances in the understanding and management of angioimmunoblastic T-cell lymphoma, British Journal of Haematology, vol.9, issue.Suppl. 2, pp.673-689, 2010. ,
DOI : 10.1111/j.1365-2141.2009.08003.x
The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells, Blood, vol.109, issue.11, pp.4952-4963, 2007. ,
DOI : 10.1182/blood-2006-10-055145
Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?, Oncogene, vol.114, issue.15, pp.1869-1875, 2013. ,
DOI : 10.1038/onc.2012.281
The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature. Clinical cancer research : an official journal of the, pp.3022-3029, 2012. ,
Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy, Cancer Discovery, vol.1, issue.1, pp.54-67, 2011. ,
DOI : 10.1158/2159-8274.CD-10-0028
Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer, Journal of Clinical Oncology, vol.28, issue.1, pp.105-113, 2010. ,
DOI : 10.1200/JCO.2009.23.7370
Reversible Senescence in Human CD4+CD45RA+CD27- Memory T Cells, The Journal of Immunology, vol.187, issue.5, pp.2093-2100, 2011. ,
DOI : 10.4049/jimmunol.1100978
Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study, Annals of Oncology, vol.25, issue.3, pp.611-618, 2014. ,
DOI : 10.1093/annonc/mdt556
A Phase I Study of Nonmyeloablative Chemotherapy and Adoptive Transfer of Autologous Tumor Antigen-Specific T Lymphocytes in Patients With Metastatic Melanoma, Journal of Immunotherapy, vol.25, issue.3, pp.243-251, 2002. ,
DOI : 10.1097/00002371-200205000-00007
Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens, Journal of Clinical Oncology, vol.26, issue.32, pp.5233-5239, 2008. ,
DOI : 10.1200/JCO.2008.16.5449
CD127 and CD25 Expression Defines CD4+ T Cell Subsets That Are Differentially Depleted during HIV Infection, The Journal of Immunology, vol.180, issue.8, pp.5582-5592, 2008. ,
DOI : 10.4049/jimmunol.180.8.5582
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683429
Cancer immunoediting: from immunosurveillance to tumor escape, Nature Immunology, vol.3, issue.11, pp.991-998, 2002. ,
DOI : 10.1038/ni1102-991
Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs, Clinical Immunology, vol.140, issue.3, pp.218-222, 2011. ,
DOI : 10.1016/j.clim.2011.04.014
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance, Nature, vol.127, issue.7261, pp.282-286, 2009. ,
DOI : 10.1038/nature08296
High-throughput sequencing of T-cell receptors reveals a homogeneous repertoire of tumour-infiltrating lymphocytes in ovarian cancer, The Journal of Pathology, vol.39, issue.Suppl 1, pp.433-440, 2013. ,
DOI : 10.1002/path.4260
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells, Nature, vol.31, issue.7355, pp.226-230, 2011. ,
DOI : 10.1038/nature10169
Early Detection of Tumor Cells by Innate Immune Cells Leads to Treg Recruitment through CCL22 Production by Tumor Cells, Cancer Research, vol.71, issue.19, pp.6143-6152, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0573
URL : https://hal.archives-ouvertes.fr/hal-00811875
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nature Immunology, vol.4, issue.4, pp.330-336, 2003. ,
DOI : 10.1038/ni904
A function for interleukin 2 in Foxp3-expressing regulatory T cells, Nature Immunology, vol.171, issue.11, pp.1142-1151, 2005. ,
DOI : 10.1186/gb-2004-5-10-r80
gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory, Journal of Experimental Medicine, vol.180, issue.1, pp.157-163, 1994. ,
DOI : 10.1084/jem.180.1.157
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells, The Journal of Experimental Medicine, vol.63, issue.13, pp.3015-3029, 2009. ,
DOI : 10.1016/j.molimm.2007.08.013
regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients, International Journal of Cancer, vol.68, pp.2635-2643, 2010. ,
DOI : 10.1002/ijc.24989
The immune contexture in human tumours: impact on clinical outcome, Nature Reviews Cancer, vol.29, issue.4, pp.298-306, 2012. ,
DOI : 10.1038/nrc3245
Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response, Cancer Research, vol.71, issue.14, pp.4821-4833, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0950
Increased expression of interleukin 17 in inflammatory bowel disease, Gut, vol.52, issue.1, pp.65-70, 2003. ,
DOI : 10.1136/gut.52.1.65
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome, Science, vol.313, issue.5795, pp.1960-1964, 2006. ,
DOI : 10.1126/science.1129139
Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule, Breast Cancer Research, vol.266, issue.4, p.48, 2010. ,
DOI : 10.1001/jama.1991.03470120074036
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1?????dependent adaptive immunity against tumors, Nature Medicine, vol.7, issue.10, pp.1170-1178, 2009. ,
DOI : 10.1038/nm.2028
URL : https://hal.archives-ouvertes.fr/hal-00419823
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients, Cancer Immunology, Immunotherapy, vol.95, issue.5, pp.641-648, 2007. ,
DOI : 10.1007/s00262-006-0225-8
Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome, Cancer Research, vol.69, issue.5, 2000. ,
DOI : 10.1158/0008-5472.CAN-08-2360
Assessment of CD4+?? T cells specific for the tumor antigen SSX-1 in cancer-free individuals, Cancer Immunology, Immunotherapy, vol.117, issue.8, pp.1183-1192, 2007. ,
DOI : 10.1007/s00262-006-0269-9
Restoring Immune Function of Tumor-Specific CD4+ T Cells during Recurrence of Melanoma, The Journal of Immunology, vol.190, issue.9, pp.4899-4909, 2013. ,
DOI : 10.4049/jimmunol.1300271
Naive T Cells Transiently Acquire a Memory-like Phenotype during Homeostasis-Driven Proliferation, The Journal of Experimental Medicine, vol.161, issue.4, pp.557-564, 2000. ,
DOI : 10.1016/S1074-7613(00)80564-6
T Cells, The Journal of Experimental Medicine, vol.157, issue.12, pp.1515-1522, 2002. ,
DOI : 10.1084/jem.192.5.659
Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo, Proceedings of the National Academy of Sciences of the United States of America, pp.10468-10473, 2012. ,
DOI : 10.1073/pnas.1201131109
CD4+ follicular helper T cell infiltration predicts breast cancer survival, Journal of Clinical Investigation, vol.123, issue.7, pp.2873-2892, 2013. ,
DOI : 10.1172/JCI67428DS1
Human TH17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN-??-Secreting Cells as They Differentiate into Effector T Cells In Vivo, Cancer Research, vol.72, issue.5, pp.1059-1063, 2012. ,
DOI : 10.1158/0008-5472.CAN-11-3432
Blockade of B7-H1 (Programmed Death Ligand 1) Enhances Humoral Immunity by Positively Regulating the Generation of T Follicular Helper Cells, The Journal of Immunology, vol.186, issue.10, pp.5648-5655, 2011. ,
DOI : 10.4049/jimmunol.1003161
Hallmarks of Cancer: The Next Generation, Cell, vol.144, issue.5, pp.646-674, 2011. ,
DOI : 10.1016/j.cell.2011.02.013
Interleukin 17???producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages, Nature Immunology, vol.173, issue.11, pp.1123-1132, 2005. ,
DOI : 10.1016/S1074-7613(00)80470-7
Immune Suppression in Premalignant Respiratory Papillomas: Enriched Functional CD4+Foxp3+ Regulatory T Cells and PD-1/PD-L1/L2 Expression, Clinical cancer research : an official journal of the American Association for Cancer Research, pp.1925-1935, 2012. ,
DOI : 10.1158/1078-0432.CCR-11-2941
Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype, The Journal of experimental medicine, vol.209, pp.2113-2126, 2012. ,
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma, New England Journal of Medicine, vol.363, issue.8, pp.711-723, 2010. ,
DOI : 10.1056/NEJMoa1003466
Control of Regulatory T Cell Development by the Transcription Factor Foxp3, Science, vol.299, issue.5609, pp.1057-1061, 2003. ,
DOI : 10.1126/science.1079490
Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1, New England Journal of Medicine, vol.358, issue.25, pp.2698-2703, 2008. ,
DOI : 10.1056/NEJMoa0800251
Microbial Lipopeptides Induce the Production of IL-17 in Th Cells, The Journal of Immunology, vol.165, issue.11, pp.6107-6115, 2000. ,
DOI : 10.4049/jimmunol.165.11.6107
Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma: A Multicenter Phase II Study, Journal of Clinical Oncology, vol.30, issue.8, pp.837-842, 2012. ,
DOI : 10.1200/JCO.2011.37.3472
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death, EMBO J, vol.11, pp.3887-3895, 1992. ,
The Orphan Nuclear Receptor ROR??t Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells, Cell, vol.126, issue.6, pp.1121-1133, 2006. ,
DOI : 10.1016/j.cell.2006.07.035
Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens, Journal of immunology, vol.133, pp.754-757, 1984. ,
Adoptive T cell therapy for cancer in the clinic, Journal of Clinical Investigation, vol.117, issue.6, pp.1466-1476, 2007. ,
DOI : 10.1172/JCI32446
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice, Proceedings of the National Academy of Sciences of the United States of America 95, pp.7556-7561, 1998. ,
Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands., Proceedings of the National Academy of Sciences of the United States of America 91, pp.8462-8466, 1994. ,
DOI : 10.1073/pnas.91.18.8462
Helper activity is required for the in vivo generation of cytotoxic T lymphocytes, Journal of Experimental Medicine, vol.155, issue.3, pp.768-782, 1982. ,
DOI : 10.1084/jem.155.3.768
Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: A two-year prospective study (the DAMAGE study cohort), Arthritis & Rheumatism, vol.50, issue.4, pp.1122-1131, 2006. ,
DOI : 10.1002/art.21749
Transcriptional analysis of the B cell germinal center reaction, Proceedings of the National Academy of Sciences of the United States of America, pp.2639-2644, 2003. ,
DOI : 10.1073/pnas.0437996100
Characterization of effector functions of human peptide-specific CD4+ T-cell clones for an intracellular pathogen, Human Immunology, vol.69, issue.8, pp.475-483, 2008. ,
DOI : 10.1016/j.humimm.2008.05.008
Regulation of CD4+ T-cell polarization by suppressor of cytokine signalling proteins, Immunology, vol.281, issue.2, pp.101-111, 2012. ,
DOI : 10.1111/j.1365-2567.2011.03520.x
A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clinical cancer research : an official journal of the American Association for, Cancer Research, vol.16, pp.4583-4594, 2010. ,
Adaptive immunity maintains occult cancer in an equilibrium state, Nature, vol.410, issue.7171, pp.903-907, 2007. ,
DOI : 10.1038/nature06309
Phenotype of neoplastic cells in angioimmunoblastic T-cell lymphoma is consistent with activated follicular B helper T cells, Blood, vol.108, issue.3, pp.1110-1111, 2006. ,
DOI : 10.1182/blood-2006-01-0394
Cutting Edge: Murine Vascular Endothelium Activates and Induces the Generation of Allogeneic CD4+25+Foxp3+ Regulatory T Cells, The Journal of Immunology, vol.175, issue.10, pp.6265-6270, 2005. ,
DOI : 10.4049/jimmunol.175.10.6265
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments, Blood, vol.114, issue.6, pp.1141-1149, 2009. ,
DOI : 10.1182/blood-2009-03-208249
Induction of IL-17+ T Cell Trafficking and Development by IFN-??: Mechanism and Pathological Relevance in Psoriasis, The Journal of Immunology, vol.181, issue.7, pp.4733-4741, 2008. ,
DOI : 10.4049/jimmunol.181.7.4733
CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers, Cancer research, vol.65, pp.465-472, 2005. ,
Relationship between B7-H4, Regulatory T Cells, and Patient Outcome in Human Ovarian Carcinoma, Cancer Research, vol.67, issue.18, pp.8900-8905, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-1866
Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment, The Journal of Immunology, vol.178, issue.11, pp.6730-6733, 2007. ,
DOI : 10.4049/jimmunol.178.11.6730
Prognostic impact of B-cell density in cutaneous melanoma, Cancer Immunology, Immunotherapy, vol.4, issue.12, pp.1729-1738, 2011. ,
DOI : 10.1007/s00262-011-1071-x
Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating foxp3+ regulatory T cells. Clinical cancer research : an official journal of the American Association for, Cancer Research, vol.14, pp.2413-2420, 2008. ,
Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer. Cancer immunology, immunotherapy : CII 60, pp.909-918, 2011. ,
In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival, The Journal of Pathology, vol.5, issue.3, pp.389-400, 2011. ,
DOI : 10.1002/path.2866
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation, The Journal of Experimental Medicine, vol.71, issue.2, pp.233-240, 2005. ,
DOI : 10.1038/nri802
Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+???CD45RA+???CD27??? T cells: the potential involvement of interleukin-7 in this process, Immunology, vol.30, issue.3, pp.326-339, 2011. ,
DOI : 10.1111/j.1365-2567.2010.03386.x
Regulatory T cell development in the absence of functional Foxp3, Nature Immunology, vol.174, issue.4, pp.359-368, 2007. ,
DOI : 10.1186/gb-2004-5-10-r80
Effector/Memory but Not Naive Regulatory T Cells Are Responsible for the Loss of Concomitant Tumor Immunity, The Journal of Immunology, vol.182, issue.10, pp.6095-6104, 2009. ,
DOI : 10.4049/jimmunol.0803829
TCR repertoires of intratumoral T-cell subsets, Immunological Reviews, vol.10, issue.1, pp.72-82, 2014. ,
DOI : 10.1111/imr.12140
IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma, Biochemical and Biophysical Research Communications, vol.407, issue.2, pp.348-354, 2011. ,
DOI : 10.1016/j.bbrc.2011.03.021
The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer, Cancer Letters, vol.333, issue.2, pp.222-228, 2013. ,
DOI : 10.1016/j.canlet.2013.01.036
IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?, Cytokine, vol.41, issue.2, pp.84-91, 2008. ,
DOI : 10.1016/j.cyto.2007.09.014
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells, Journal of Clinical Investigation, vol.115, issue.4, pp.1049-1059, 2005. ,
DOI : 10.1172/JCI200523139
Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease, Journal of Clinical Investigation, vol.116, issue.2, pp.322-333, 2006. ,
DOI : 10.1172/JCI25720
Evidence for in situ amplification of cytotoxic T-lymphocytes with antitumor activity in a human regressive melanoma, Cancer research, vol.53, pp.3569-3573, 1993. ,
Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11, The Journal of Experimental Medicine, vol.154, issue.5, pp.871-876, 1999. ,
DOI : 10.1002/(SICI)1097-0215(19980130)75:3<384::AID-IJC10>3.0.CO;2-9
Orchestration of macrophage polarization, Blood, vol.114, issue.15, pp.3135-3136, 2009. ,
DOI : 10.1182/blood-2009-07-231795
T cell response, The Journal of Experimental Medicine, vol.2012, issue.8, pp.1603-1619, 2013. ,
DOI : 10.1089/omi.2009.0014
Regulation and Functions of Blimp-1 in T and B Lymphocytes, Annual Review of Immunology, vol.26, issue.1, pp.133-169, 2008. ,
DOI : 10.1146/annurev.immunol.26.021607.090241
Endosomal Proteases Influence the Repertoire of MAGE-A3 Epitopes Recognized In vivo by CD4+ T Cells, Cancer Research, vol.68, issue.5, pp.1555-1562, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-5233
CCL17 and CCL22 chemokines within tumor microenvironment are related to infiltration of regulatory T cells in esophageal squamous cell carcinoma, Diseases of the Esophagus, vol.23, pp.422-429, 2010. ,
DOI : 10.1111/j.1442-2050.2009.01029.x
Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer, Cancer Science, vol.13, issue.9, pp.1947-1954, 2010. ,
DOI : 10.1111/j.1349-7006.2010.01624.x
Interleukin-7 receptor expression: intelligent design, Nature Reviews Immunology, vol.18, issue.2, pp.144-154, 2007. ,
DOI : 10.1038/nri2023
THE PERIPHERAL BLOOD LEUKOCYTE PHENOTYPE IN PATIENTS WITH BREAST CANCER: EFFECT OF DOXORUBICIN/PACLITAXEL COMBINATION CHEMOTHERAPY, Immunopharmacology and Immunotoxicology, vol.14, issue.2, pp.163-173, 2001. ,
DOI : 10.1007/BF00682702
Follicular center helper T-cell (TFH) marker positive mycosis fungoides/Sezary syndrome, Modern Pathology, vol.1, issue.1, pp.32-43, 2013. ,
DOI : 10.1182/blood-2010-05-287664
Spontaneous and Homeostatic Proliferation of CD4 T Cells Are Regulated by Different Mechanisms, The Journal of Immunology, vol.174, issue.10, pp.6039-6044, 2005. ,
DOI : 10.4049/jimmunol.174.10.6039
Neutrophils recruit regulatory Tcells into tumors via secretion of CCL17-A new mechanism of impaired antitumor immunity, Z. G. Int J Cancer, 2014. ,
The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation, European Journal of Immunology, vol.227, issue.1, pp.18-27, 1971. ,
DOI : 10.1002/eji.1830010104
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor, Immunity, vol.30, issue.6, pp.899-911, 2009. ,
DOI : 10.1016/j.immuni.2009.03.019
The Role of the Basic Helix-Loop-Helix Transcription Factor Dec1 in the Regulatory T Cells, The Journal of Immunology, vol.185, issue.12, pp.7330-7339, 2010. ,
DOI : 10.4049/jimmunol.1001381
CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer, International Journal of Cancer, vol.31, issue.10, pp.2286-2293, 2008. ,
DOI : 10.1002/ijc.23392
Antigenspecific functions of a CD4+ subset of human T lymphocytes with granular morphology, Journal of immunology, vol.136, pp.2095-2102, 1986. ,
A distinct subset of human CD4+ cells with a limited alloreactive T cell receptor repertoire, Journal of immunology, vol.143, pp.2783-2789, 1989. ,
Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival, Targeted Oncology, vol.21, issue.10, pp.55-68, 2012. ,
DOI : 10.1007/s11523-012-0210-4
Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II???restricted cytotoxic T lymphocytes, Nature Immunology, vol.158, issue.3, pp.281-289, 2013. ,
DOI : 10.1016/S0022-1759(03)00265-5
LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice, Science, vol.255, issue.5051, pp.1576-1578, 1992. ,
DOI : 10.1126/science.1347959
A different immunologic profile characterizes patients with HER-2-overexpressing and HER-2-negative locally advanced breast cancer: implications for immune-based therapies, Breast Cancer Research, vol.10, issue.6, p.117, 2011. ,
DOI : 10.1158/1078-0432.CCR-1016-03
Lymphocyte subpopulations in patients with advanced breast cancer submitted to neoadjuvant chemotherapy, Tumori, vol.86, pp.403-407, 2000. ,
Functional subsets of CD4 T cells in rheumatoid synovitis, Arthritis & Rheumatism, vol.40, issue.12, pp.2108-2116, 1998. ,
DOI : 10.1002/1529-0131(199812)41:12<2108::AID-ART5>3.0.CO;2-Q
CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer, Clinical cancer research : an official journal of the American Association for Cancer Research, pp.3281-3292, 2012. ,
DOI : 10.1158/1078-0432.CCR-12-0234
Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor, Immunity, vol.11, issue.2, pp.141-151, 1999. ,
DOI : 10.1016/S1074-7613(00)80089-8
Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells, Journal of Experimental Medicine, vol.155, issue.4, pp.1063-1074, 1982. ,
DOI : 10.1084/jem.155.4.1063
Interleukin-17 promotes angiogenesis and tumor growth, Blood, vol.101, issue.7, pp.2620-2627, 2003. ,
DOI : 10.1182/blood-2002-05-1461
IL-17 Enhances the Net Angiogenic Activity and In Vivo Growth of Human Non-Small Cell Lung Cancer in SCID Mice through Promoting CXCR-2-Dependent Angiogenesis, The Journal of Immunology, vol.175, issue.9, pp.6177-6189, 2005. ,
DOI : 10.4049/jimmunol.175.9.6177
Bcl6 Mediates the Development of T Follicular Helper Cells, Science, vol.325, issue.5943, pp.1001-1005, 2009. ,
DOI : 10.1126/science.1176676
ERP57 Membrane Translocation Dictates the Immunogenicity of Tumor Cell Death by Controlling the Membrane Translocation of Calreticulin, The Journal of Immunology, vol.181, issue.4, pp.2533-2543, 2008. ,
DOI : 10.4049/jimmunol.181.4.2533
Calreticulin exposure dictates the immunogenicity of cancer cell death, Nature Medicine, vol.279, issue.1, pp.54-61, 2007. ,
DOI : 10.1038/nm1523
URL : https://hal.archives-ouvertes.fr/inserm-00451702
Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients, Breast Cancer Research and Treatment, vol.135, issue.Suppl 5, pp.107-116, 2012. ,
DOI : 10.1007/s10549-012-2245-8
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile, Nature Immunology, vol.105, issue.4, pp.405-411, 2012. ,
DOI : 10.1084/jem.20102065
Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors, Nature Reviews Immunology, vol.36, issue.11, pp.799-804, 2012. ,
DOI : 10.1038/nri3321
Cancer immunology???analysis of host and tumor factors for personalized medicine, Nature Reviews Clinical Oncology, vol.25, issue.12, pp.711-719, 2011. ,
DOI : 10.1038/nrclinonc.2011.122
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice, Nature Medicine, vol.9, issue.12, pp.1477-1483, 2003. ,
DOI : 10.1038/nm955
A Critical Role for IL-21 in Regulating Immunoglobulin Production, Science, vol.298, issue.5598, pp.1630-1634, 2002. ,
DOI : 10.1126/science.1077002
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17, Nature Immunology, vol.103, issue.11, pp.1133-1141, 2005. ,
DOI : 10.1038/35051100
The CD4+ T-cell subset lacking expression of the CD28 costimulatory molecule is expanded and shows a higher activation state in multiple sclerosis, Journal of Neuroimmunology, vol.243, issue.1-2, pp.1-11, 2012. ,
DOI : 10.1016/j.jneuroim.2011.11.008
DNA methylation controls Foxp3 gene expression, European Journal of Immunology, vol.175, issue.6, pp.1654-1663, 2008. ,
DOI : 10.1002/eji.200838105
T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts, The Journal of Experimental Medicine, vol.62, issue.3, pp.637-650, 2010. ,
DOI : 10.1084/jem.20062056
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839156
Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells, The Journal of Immunology, vol.192, issue.8, pp.3507-3517, 2014. ,
DOI : 10.4049/jimmunol.1302725
Follicular B helper T cell activity is confined to CXCR5hiICOShi CD4 T cells and is independent of CD57 expression, European Journal of Immunology, vol.2, issue.7, pp.1892-1903, 2006. ,
DOI : 10.1002/eji.200636136
Lymphopenia as a Prognostic Factor for Overall Survival in Advanced Carcinomas, Sarcomas, and Lymphomas, Cancer Research, vol.69, issue.13, pp.5383-5391, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-3845
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity, Nature Immunology, vol.175, issue.3, pp.271-280, 2013. ,
DOI : 10.1016/j.immuni.2008.05.010
A systematic review of humoral immune responses against tumor antigens. Cancer immunology, immunotherapy : CII 58, pp.1535-1544, 2009. ,
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell, Nature, vol.393, issue.6684, pp.474-478, 1998. ,
DOI : 10.1038/30989
Primary Cutaneous CD4+ Small/Medium-sized Pleomorphic T-cell Lymphoma Expresses Follicular T-cell Markers, The American Journal of Surgical Pathology, vol.33, issue.1, pp.81-90, 2009. ,
DOI : 10.1097/PAS.0b013e31818e52fe
Properties and origin of human Th17 cells, Molecular Immunology, vol.47, issue.1, pp.3-7, 2009. ,
DOI : 10.1016/j.molimm.2008.12.019
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level, European Journal of Immunology, vol.101, issue.6, pp.1681-1691, 2005. ,
DOI : 10.1002/eji.200526189
Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report, pp.1676-1680, 1988. ,
Immunologic selftolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25), 1995. ,
: Function, Generation, and Maintenance, Annual Review of Immunology, vol.22, issue.1, pp.745-763, 2004. ,
DOI : 10.1146/annurev.immunol.22.012703.104702
Cyclophosphamide "metronomic" chemotherapy for palliative treatment of a young patient with advanced epithelial ovarian cancer, BMC Cancer, vol.2, issue.11, p.65, 2007. ,
DOI : 10.1038/ncponc0342
Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype, International Immunology, vol.20, issue.3, pp.375-383, 2008. ,
DOI : 10.1093/intimm/dxm151
Cxc Chemokine Receptor 5 Expression Defines Follicular Homing T Cells with B Cell Helper Function, The Journal of Experimental Medicine, vol.162, issue.11, pp.1553-1562, 2000. ,
DOI : 10.4049/jimmunol.164.4.1653
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression, Nature immunology, vol.25, issue.3, pp.303-313, 2005. ,
DOI : 10.1046/j.1365-2141.1999.01233.x
The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer, Cancer Research, vol.68, issue.13, pp.5405-5413, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-5206
Prognostic impact of tumour-infiltrating Th2 and regulatory T cells in classical Hodgkin lymphoma, Hematological Oncology, vol.82, issue.3, pp.31-39, 2009. ,
DOI : 10.1002/hon.878
A MAGE-A3 peptide presented by HLA-DP4 is recognized on tumor cells by CD4+ cytolytic T lymphocytes, Cancer research, vol.60, pp.6272-6275, 2000. ,
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells, The Journal of Experimental Medicine, vol.66, issue.7, pp.1693-1700, 2006. ,
DOI : 10.1002/eji.200425763
IFN-?? Produced by Human Papilloma Virus-18 E6-Specific CD4+ T Cells Predicts the Clinical Outcome after Surgery in Patients with High-Grade Cervical Lesions, The Journal of Immunology, vol.179, issue.10, pp.7176-7183, 2007. ,
DOI : 10.4049/jimmunol.179.10.7176
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity, Nature, vol.410, issue.6832, pp.1107-1111, 2001. ,
DOI : 10.1038/35074122
Profound tumor-specific Th2 bias in patients with malignant glioma, BMC Cancer, vol.104, issue.3, p.561, 2012. ,
DOI : 10.1002/ijc.10964
B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity, Immunity, vol.18, issue.6, pp.849-861, 2003. ,
DOI : 10.1016/S1074-7613(03)00152-3
CD4+ Th2 Cell Recognition of HLA-DR-Restricted Epitopes Derived from CAMEL: A Tumor Antigen Translated in an Alternative Open Reading Frame, The Journal of Immunology, vol.170, issue.3, pp.1490-1497, 2003. ,
DOI : 10.4049/jimmunol.170.3.1490
Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer, Annals of Oncology, vol.25, issue.1, pp.100-106, 2014. ,
DOI : 10.1093/annonc/mdt427
Immunerelated gene signatures predict the outcome of neoadjuvant chemotherapy, 2014. ,
CD8+???CD28??? and CD8+???CD57+ T cells and their role in health and disease, Immunology, vol.6, issue.1, pp.17-32, 2011. ,
DOI : 10.1111/j.1365-2567.2011.03470.x
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans, Proceedings of the National Academy of Sciences of the United States of America, pp.17945-17950, 2013. ,
DOI : 10.1073/pnas.1316796110
Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help, Science, vol.300, issue.5617, pp.339-342, 2003. ,
DOI : 10.1126/science.1083317
Cytokine production and cytolytic mechanism of CD4+ cytotoxic T lymphocytes in ex vivo expanded therapeutic Epstein-Barr virus-specific T-cell cultures, Blood, vol.99, issue.9, pp.3302-3309, 2002. ,
DOI : 10.1182/blood.V99.9.3302
Radiochemotherapy induces a favourable tumour infiltrating inflammatory cell profile in head and neck cancer, Oral Oncology, vol.48, issue.7, pp.594-601, 2012. ,
DOI : 10.1016/j.oraloncology.2012.01.024
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells, The Journal of Immunology, vol.171, issue.7, pp.3348-3352, 2003. ,
DOI : 10.4049/jimmunol.171.7.3348
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice, Cancer research, vol.59, pp.3698-3704, 1999. ,
Carcinoembryonic Antigen-Specific but Not Antiviral CD4+ T Cell Immunity Is Impaired in Pancreatic Carcinoma Patients, The Journal of Immunology, vol.181, issue.9, pp.6595-6603, 2008. ,
DOI : 10.4049/jimmunol.181.9.6595
Immunogenic death of colon cancer cells treated with oxaliplatin, Oncogene, vol.177, issue.4, pp.482-491, 2010. ,
DOI : 10.1172/JCI35180
Interleukin-17 and Interferon-?? Synergize in the Enhancement of Proinflammatory Cytokine Production by Human Keratinocytes, Journal of Investigative Dermatology, vol.111, issue.4, pp.645-649, 1998. ,
DOI : 10.1046/j.1523-1747.1998.00347.x
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells, The Journal of Immunology, vol.184, issue.7, pp.3433-3441, 2010. ,
DOI : 10.4049/jimmunol.0904028
Safety, Activity, and Immune Correlates of Anti???PD-1 Antibody in Cancer, New England Journal of Medicine, vol.366, issue.26, pp.2443-2454, 2012. ,
DOI : 10.1056/NEJMoa1200690
Human CD4+ T cells specifically recognize a shared melanomaassociated antigen encoded by the tyrosinase gene, Proceedings of the National Academy of Sciences of the United States of America 91, pp.9461-9465, 1994. ,
Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer, Cancer Research, vol.71, issue.4, pp.1263-1271, 2011. ,
DOI : 10.1158/0008-5472.CAN-10-2907
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis, The American Journal of Pathology, vol.172, issue.1, pp.146-155, 2008. ,
DOI : 10.2353/ajpath.2008.070690
Trial watch: Chemotherapy with immunogenic cell death inducers, pp.179-188, 2012. ,
Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer, pp.271-278, 2012. ,
Cancer Incidence Before and After Kidney Transplantation, JAMA, vol.296, issue.23, pp.2823-2831, 2006. ,
DOI : 10.1001/jama.296.23.2823
A peripheral circulating compartment
of natural naive CD4+ Tregs, Journal of Clinical Investigation, vol.115, issue.7, pp.1953-1962, 2005. ,
DOI : 10.1172/JCI23963
Human RORgammat+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors, Proceedings of the National Academy of Sciences of the United States of America, pp.19402-19407, 2010. ,
Cyclophosphamide Induces Differentiation of Th17 Cells in Cancer Patients, Cancer Research, vol.71, issue.3, pp.661-665, 2011. ,
DOI : 10.1158/0008-5472.CAN-10-1259
Database of T cell-defined human tumor antigens: the 2013 update, Cancer Immun, vol.13, p.15, 2013. ,
5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity, Cancer Research, vol.70, issue.8, pp.3052-3061, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-3690
Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production, Blood, vol.114, issue.17, pp.3610-3614, 2009. ,
DOI : 10.1182/blood-2009-05-223768
Phenotype, effector function, and tissue localization of PD-1-expressing human follicular helper T cell subsets, BMC Immunology, vol.12, issue.1, p.53, 2011. ,
DOI : 10.1172/JCI11902
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells, European Journal of Immunology, vol.115, issue.1, pp.129-138, 2007. ,
DOI : 10.1002/eji.200636435
Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes, Proceedings of the National Academy of Sciences, vol.102, issue.33, pp.11823-11828, 2005. ,
DOI : 10.1073/pnas.0505497102
IL-17 can promote tumor growth through an IL-6???Stat3 signaling pathway, The Journal of Experimental Medicine, vol.206, issue.7, pp.1457-1464, 2009. ,
DOI : 10.1016/j.jhep.2008.12.033
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection, Immunity, vol.27, issue.4, pp.670-684, 2007. ,
DOI : 10.1016/j.immuni.2007.09.006
Development, cytokine profile and function of human interleukin 17???producing helper T cells, Nature Immunology, vol.176, issue.9, pp.950-957, 2007. ,
DOI : 10.1084/jem.194.4.519
Interleukin-17: A Promoter in Colorectal Cancer Progression, Clinical and Developmental Immunology, vol.26, issue.6, p.436307, 2013. ,
DOI : 10.4049/jimmunol.1003251
T cells differentiated in vivo eradicate established melanoma, The Journal of Experimental Medicine, vol.146, issue.3, pp.651-667, 2010. ,
DOI : 10.1038/nm1312
Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer, Human Pathology, vol.43, issue.10, pp.1688-1694, 2012. ,
DOI : 10.1016/j.humpath.2011.12.013
Treatment of Melanoma with 5-Fluorouracil or Dacarbazine In Vitro Sensitizes Cells to Antigen-Specific CTL Lysis through Perforin/Granzyme- and Fas-Mediated Pathways, The Journal of Immunology, vol.172, issue.7, pp.4599-4608, 2004. ,
DOI : 10.4049/jimmunol.172.7.4599
Generation and Differentiation of IL-17-Producing CD4+ T Cells in Malignant Pleural Effusion, The Journal of Immunology, vol.185, issue.10, pp.6348-6354, 2010. ,
DOI : 10.4049/jimmunol.1001728
CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function, Journal of immunology, vol.152, pp.598-608, 1994. ,
Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients, The Journal of Immunology, vol.186, issue.5, pp.2739-2749, 2011. ,
DOI : 10.4049/jimmunol.1002939
Higher levels of GATA3 predict better survival in women with breast cancer, Human Pathology, vol.41, issue.12, pp.1794-1801, 2010. ,
DOI : 10.1016/j.humpath.2010.06.010
The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment, Immunity, vol.31, issue.3, pp.457-468, 2009. ,
DOI : 10.1016/j.immuni.2009.07.002
Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150), The Journal of Immunology, vol.185, issue.1, pp.190-202, 2010. ,
DOI : 10.4049/jimmunol.0903505
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function, The Journal of Experimental Medicine, vol.393, issue.12, pp.2205-2213, 1998. ,
DOI : 10.1038/373123a0
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients, Journal of Hepatology, vol.50, issue.5, pp.980-989, 2009. ,
DOI : 10.1016/j.jhep.2008.12.033
Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy, Clinical Immunology, vol.129, issue.2, pp.219-229, 2008. ,
DOI : 10.1016/j.clim.2008.07.013
An obligate cell-intrinsic function for CD28 in Tregs, Journal of Clinical Investigation, vol.123, pp.580-593, 2013. ,
DOI : 10.1172/JCI65013DS1
Impaired primary, but not secondary, immune response in breast cancer patients under adjuvant chemotherapy, Cancer, vol.2, issue.8, pp.1648-1652, 1986. ,
DOI : 10.1002/1097-0142(19861015)58:8<1648::AID-CNCR2820580812>3.0.CO;2-E
A natural cytotoxic T cell response in a spontaneously regressing human melanoma targets a neoantigen resulting from a somatic point mutation, European Journal of Immunology, vol.287, issue.2, pp.592-601, 1999. ,
DOI : 10.1002/(SICI)1521-4141(199902)29:02<592::AID-IMMU592>3.0.CO;2-2
Inhibitory B7-family molecules in the tumour microenvironment, Nature Reviews Immunology, vol.106, issue.6, pp.467-477, 2008. ,
DOI : 10.1038/nri2326
TH17 cells in tumour immunity and immunotherapy, Nature Reviews Immunology, vol.8, issue.4, pp.248-256, 2010. ,
DOI : 10.1038/nri2742