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Étude et mise au point d'une plateforme de biodétection de micro-organismes couplant immunocapteur a ondes de love et dispositfs PDMS microfluidiques

Abstract : For several decades, biosensors are becoming increasingly developing through their areas of application. In this context, through a multidisciplinary approach, we designed a measuring cell and microfluidic chips of PDMS polymer, coupled with Love wave immunosensor, to provide a platform for the rapid detection of bio-organisms. This new platform allowed direct and specific antibodies and Escherichia Coli whole living bacteria detection. It also helped to significantly reduce the detection time (from several hours to a few minutes), simplify testing protocols, and introduce "dynamic behaviour" of biological phenomena. The specificity of the detection is based on the functionalization of the sensor surface, the platform can be adapted to the detection of a wide spectrum of bioorganisms compounds or in a liquid medium.
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https://tel.archives-ouvertes.fr/tel-00985746
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Submitted on : Wednesday, April 30, 2014 - 1:00:10 PM
Last modification on : Thursday, January 11, 2018 - 6:21:09 AM

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  • HAL Id : tel-00985746, version 1

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Hakim Tarbague. Étude et mise au point d'une plateforme de biodétection de micro-organismes couplant immunocapteur a ondes de love et dispositfs PDMS microfluidiques. Micro et nanotechnologies/Microélectronique. Université Sciences et Technologies - Bordeaux I, 2011. Français. ⟨tel-00985746⟩

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