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Analyse et optimisation des performances de la technique VMAT pour son utilisation en radiothérapie

Abstract : VMAT (Volumetric Modulated Arc Therapy) technique has been introduced in 2009, it combines advantage of arctherapy techniques with advantage of IMRT (Intensity Modulated Radio Therapy) techniques delivered with stationary beams. The purpose of the thesis is to optimise implementation conditions of VMAT for a Synergy/Elekta linear accelerator in order to secure the technique and to be able to benefit from potentially expected clinical improvement. From analysis of influence of various work flow parameters, we propose treatment optimisation factors both on dosimetric planning and on delivering control on the accelerator. We show that if optimisation quality depends on intrinsic accelerator characteristics, it also depends very much on configuration of treatment planning system (TPS). We highlight compared differences between Beam Modulateur (leaf width of 4 mm) and MLCi2 (leaf width of 10 mm) on dose distribution and on efficiency. We show that if differences of dose distributions are small for two major TPS (Pinnacle/Philips and Monao/Elekta), the differences of implemented methods affect dose distribution of healthy tissues. We suggest quality control set for accelerators, for treatment plans and for treatment delivery. In order to provide a high safety level on delivered dose, we suggest an evaluation method of the real fluence provided during treatment delivery by analysing accelerator parameters. We establish that optimised process of VMAT treatment provides better performance than RCMI techniques delivered with stationary beams for the four major cancer cases that has been studied.
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Contributor : Caroline Lafond <>
Submitted on : Friday, December 20, 2013 - 6:09:25 PM
Last modification on : Friday, January 15, 2021 - 3:33:48 AM
Long-term archiving on: : Friday, March 21, 2014 - 9:36:16 AM


  • HAL Id : tel-00921677, version 1



Caroline Lafond. Analyse et optimisation des performances de la technique VMAT pour son utilisation en radiothérapie. Traitement du signal et de l'image [eess.SP]. Université Rennes 1, 2013. Français. ⟨tel-00921677⟩



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