M. Karas, D. Bachmann, U. Bahr, and F. Hillenkamp, Matrix-assisted ultraviolet laser desorption of non-volatile compounds, International Journal of Mass Spectrometry and Ion Processes, vol.78, p.53, 1987.
DOI : 10.1016/0168-1176(87)87041-6

H. Tanaka, Y. Waki, S. Ido, Y. Akita, T. Yoshida et al., Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, vol.12, issue.8, p.151, 1988.
DOI : 10.1002/rcm.1290020802

B. Fenn and J. , Ion formation from charged droplets: roles of geometry, energy, and time, Journal of the American Society for Mass Spectrometry, vol.4, issue.7, p.524, 1993.
DOI : 10.1016/1044-0305(93)85014-O

J. M. Takats, B. Wiseman, R. G. Gologan, and . Cooks, Electrosonic Spray Ionization. A Gentle Technique for Generating Folded Proteins and Protein Complexes in the Gas Phase and for Studying Ion???Molecule Reactions at Atmospheric Pressure, Analytical Chemistry, vol.76, issue.14, p.4050, 2004.
DOI : 10.1021/ac049848m

J. M. Takats, R. G. Wiseman, and . Cooks, Ambient mass spectrometry using desorption electrospray ionization (DESI): instrumentation, mechanisms and applications in forensics, chemistry, and biology, Journal of Mass Spectrometry, vol.76, issue.2, p.1261, 2005.
DOI : 10.1002/jms.922

H. Andersen and H. L. Bay, Nonlinear effects in heavy???ion sputtering, Journal of Applied Physics, vol.33, issue.14, p.953, 1974.
DOI : 10.1080/00337577008235616

H. Andersen and H. L. Bay, Heavy???ion sputtering yields of gold: Further evidence of nonlinear effects, Journal of Applied Physics, vol.13, issue.10, pp.2416-2422, 1975.
DOI : 10.1016/0022-3115(74)90248-7

B. Postawa, M. Czerwinski, E. J. Szewczyk, N. Smiley, B. J. Winograd et al., versus Ga Bombardment of Ag{111} As Explored by Molecular Dynamics Simulations, Analytical Chemistry, vol.75, issue.17, pp.4402-4407, 2003.
DOI : 10.1021/ac034387a

M. Novikov, S. Caroff, J. Della-negra, M. Depauw, Y. L. Fallavier et al., The Aun cluster probe in secondary ion mass spectrometry: influence of the projectile size and energy on the desorption/ionization rate from biomolecular solids, Rapid Communications in Mass Spectrometry, vol.2, issue.204, pp.1851-1857, 2005.
DOI : 10.1002/rcm.1995

URL : https://hal.archives-ouvertes.fr/in2p3-00024292

J. Della-negra, C. Depauw, E. A. Guillermier, and . Schweikert, Massive clusters: Secondary emission from qkeV to qMeV. New emission processes? New SIMS probe?, Surface and Interface Analysis, vol.140, issue.1-2, pp.62-65, 2011.
DOI : 10.1002/sia.3416

URL : https://hal.archives-ouvertes.fr/in2p3-00465039

J. Della-negra, J. Arianer, S. V. Depauw, E. A. Verkhoturov, and . Schweikert, The Pegase project, a new solid surface probe: focused massive cluster ion beams, Surface and Interface Analysis, vol.231, issue.232, pp.66-69, 2011.
DOI : 10.1002/sia.3478

URL : https://hal.archives-ouvertes.fr/in2p3-00577202

B. Slodzian, F. Daigne, F. Girard, F. Boust, and . Hillion, Scanning secondary ion analytical microscopy with parallel detection, Biology of the Cell, vol.74, issue.1, p.43, 1992.
DOI : 10.1016/0248-4900(92)90007-N

I. S. Gilmore, Role of operating conditions in TOF-SIMS Surface Analysis by Mass Spectrometry, second Edition

J. Cheng and N. Winograd, Probe, Analytical Chemistry, vol.77, issue.11, p.3651, 2005.
DOI : 10.1021/ac048131w

X. A. Fletcher, J. C. Conlan, N. P. Vickerman, and . Lockyer, Molecular depth profiling of organic and biological materials, Applied Surface Science, vol.252, issue.19, pp.6513-6516, 2006.
DOI : 10.1016/j.apsusc.2006.02.213

B. Mine, J. Douhard, L. Brison, and . Houssiau, Molecular depth-profiling of polycarbonate with low-energy Cs+ ions, Rapid Communications in Mass Spectrometry, vol.6, issue.220, pp.2680-2684, 2007.
DOI : 10.1002/rcm.3135

L. Wehbe and . Houssiau, 10052. 61 Method for surface treatment with extra-low-speed ion beam. European Patent Application EP0516480, Kind Code: A2. 62 I, Anal. Chem. Yamada, T. Takag, NIM B, vol.82, issue.21, pp.120-123, 1987.

K. Ninomiya, H. Ichiki, Y. Yamada, . T. Nakata, T. Seki et al., Precise and fast secondary ion mass spectrometry depth profiling of polymer materials with large Ar cluster ion beams, Rapid Communications in Mass Spectrometry, vol.6, issue.11, pp.1601-1606, 2009.
DOI : 10.1002/rcm.4046

L. S. Lee, S. Ninomiya, J. Matsuo, I. S. Gilmore, M. P. Seah et al., Organic Depth Profiling of a Nanostructured Delta Layer Reference Material Using Large Argon Cluster Ions, Analytical Chemistry, vol.82, issue.1, pp.98-105, 2010.
DOI : 10.1021/ac901045q

J. Toyoda, T. Matsuo, I. Aoki, D. B. Yamada, and . Fenner, Secondary ion mass spectrometry with gas cluster ion beams, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, vol.190, issue.1-4, pp.860-864, 2002.
DOI : 10.1016/S0168-583X(02)00463-9

K. Tanaka, T. Moritani, N. Hirota, I. Toyoda, N. Yamada et al., Enhanced surface sensitivity in secondary ion mass spectrometric analysis of organic thin films using size-selected Ar gas-cluster ion projectiles, Rapid Communications in Mass Spectrometry, vol.12, issue.232, pp.1405-1410, 2010.
DOI : 10.1002/rcm.4529

M. Mochiji, K. Hashinokuchi, N. Moritani, and . Toyoda, Matrix-free detection of intact ions from proteins in argon-cluster secondary ion mass spectrometry, Rapid Communications in Mass Spectrometry, vol.232, issue.413, pp.648-652, 2009.
DOI : 10.1002/rcm.3922

L. S. Lee, M. P. Seah, and I. S. Gilmore, Artifacts in the sputtering of inorganics by C60n+, Applied Surface Science, vol.255, issue.4, pp.934-937, 2008.
DOI : 10.1016/j.apsusc.2008.05.163

L. Toutain and A. Bousquet-melou, Bioavailability and its assessment, Journal of Veterinary Pharmacology and Therapeutics, vol.6, issue.6, pp.455-466, 2004.
DOI : 10.1016/S0304-4017(03)00008-6

URL : https://hal.archives-ouvertes.fr/hal-00517568

H. S. Chow, N. Anavy, D. Salazar, H. D. Frank, and D. S. Albert, Determination of celecoxib in human plasma using solid-phase extraction and high-performance liquid chromatography, Journal of Pharmaceutical and Biomedical Analysis, vol.34, issue.1, p.167, 2004.
DOI : 10.1016/j.japna.2003.08.018

K. Srinivasu, C. L. Narayana, D. S. Rao, and G. O. Reddy, A validated LC method for the quantitative determination of celecoxib in pharmaceutical dosage forms and purity evaluation in bulk drugs, Journal of Pharmaceutical and Biomedical Analysis, vol.22, issue.6, p.949, 2000.
DOI : 10.1016/S0731-7085(00)00303-4

N. Saha, C. P. Sajeev, S. P. Jadhav, N. Patil, and . Srinivasan, Determination of celecoxib in pharmaceutical formulations using UV spectrophotometry and liquid chromatography, Journal of Pharmaceutical and Biomedical Analysis, vol.28, issue.3-4, p.741, 2002.
DOI : 10.1016/S0731-7085(01)00678-1

M. Ghoneim and A. M. Beltagi, Adsorptive stripping voltammetric determination of the anti-inflammatory drug celecoxib in pharmaceutical formulation and human serum, Talanta, vol.60, issue.5, p.911, 2003.
DOI : 10.1016/S0039-9140(03)00151-6

S. El-desoky, E. M. Ghoneim, and M. M. Ghoneim, Voltammetric behavior and assay of the antibiotic drug cefazolin sodium in bulk form and pharmaceutical formulation at a mercury electrode, Journal of Pharmaceutical and Biomedical Analysis, vol.39, issue.5, pp.1051-1056, 2005.
DOI : 10.1016/j.jpba.2005.05.020

B. Decomminck and . Lvan-oystaeyon, High resolution depth profiling of F, Ne and Na in materials, Nuclear Instruments and Methods in Physics Research, vol.218, issue.1-3, p.165, 1983.
DOI : 10.1016/0167-5087(83)90974-2

K. Nsouli, A. Zahraman, S. Bejjani, F. Assi, M. El-yazibi et al., On the direct quantification of celecoxib in commercial solid drugs using the TT-PIXE and TT-PIGE techniques, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, vol.249, issue.1-2, pp.692-696, 2006.
DOI : 10.1016/j.nimb.2006.03.119

A. Nsouli, S. Bejjani, A. Della-negra, J. P. Gardon, and . Thomas, Ion Beam Analysis and PD-MS As New Analytical Tools for Quality Control of Pharmaceuticals: Comparative Study from Fluphenazine in Solid Dosage Forms, Analytical Chemistry, vol.82, issue.17, pp.7309-7318, 2010.
DOI : 10.1021/ac101247d

. Apport, analyse élémentaire (IBA) et moléculaire (ToF-SIMS) par faisceaux d'ions a l'étude de matériaux d'intérêt environnemental et pharmaceutique-Alice Bejjani-N° d, pp.302-2009

C. Duprat, M. Engrand, and . Maurette, Micrometeorites from Central Antarctic snow: The CONCORDIA collection, Advances in Space Research, vol.39, issue.4, pp.605-61, 2007.
DOI : 10.1016/j.asr.2006.05.029

I. Matter, 97 NASA?s Origins Program, 1999.

J. Grossemy, Z. Borg, A. Djouadi, L. Simionovici, D. Lemelle et al., In-situ Fe XANES of extraterrestrial grains trapped in aerogel collectors: An analytical test for the interpretation of Stardust samples analyses, Planetary and Space Science, vol.55, issue.7-8, p.966, 2007.
DOI : 10.1016/j.pss.2006.11.004

URL : https://hal.archives-ouvertes.fr/hal-00291541

M. M. Caro, E. Dartois, and K. Nakamura-messenger, Characterization of the carbon component in cometary Stardust samples by means of infrared and Raman spectroscopy, Astronomy and Astrophysics, vol.485, issue.3, p.743, 2008.
DOI : 10.1051/0004-6361:20078879

G. M. Dartois, D. Caro, G. Deboffle, and L. Montagnac, Ultraviolet photoproduction of ISM dust, Astronomy & Astrophysics, vol.432, issue.3, pp.895-908, 2005.
DOI : 10.1051/0004-6361:20042094

K. Bajt, Micro-PIXE measurements in meteorites as a source of new information, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, vol.54, issue.1-3, p.317, 1991.
DOI : 10.1016/0168-583X(91)95532-I

G. W. Pizzarello, G. J. Cooper, and . Flynn, The nature and distribution of the organic material in carbonaceous chondrites and interplanetary dust particles, Meteorites and the Early Solar System II, pp.625-651, 2006.

J. M. Hayes, Organic constituents of meteorites???a review, Geochimica et Cosmochimica Acta, vol.31, issue.9, pp.1395-1440, 1967.
DOI : 10.1016/0016-7037(67)90019-1

J. R. Cronin, S. Pizzarello, and D. P. Et-cruikshank, Organic matter in carbonaceous chondrites, planetary satellites, asteroids and comets. Dans Meteorites and the early solar system, pp.819-852, 1988.

J. R. Cronin and S. Chang, Organic matter in meteorites : molecular and isotopic analysis of the Murchison meteorite. The chemistry of life's origins, pp.209-258, 1993.

S. Gilmour, G. W. Pizzarello, G. J. Cooper, and . Flynn, The nature and distribution of the organic material in carbonaceous chondrites and interplanetary dust particles, Meteorites and the early solar system II, pp.625-651, 2003.

C. M. Busemann, . O-'d, L. R. Alexander, and . Nittler, Characterization of insoluble organic matter in primitive meteorites by microRaman spectroscopy, Meteoritics & Planetary Science, vol.61, issue.2, pp.1387-1416, 2007.
DOI : 10.1111/j.1945-5100.2007.tb00581.x