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L. Ms-des-extraits-de and C. , micranthum (figure 28) et M. scaber (figure 29) a indiqué une faible différence entre les lots de chaque drogue végétale. En effet, les scores des différents échantillons sont proches, même si on observe une distinction entre certains lots : le cas des lots CM2, pp.1-2

L. Htgc, MS permet de distinguer les différents lots en fonction des dates d'obtention donc des variations liées à la conservation des échantillons. Par contre la NARP-LC/MS permet de séparer les lots de drogues végétales en fonction des différentes sources d'obtention et

H. Ms and N. , MS) proposées dans le cadre de nos travaux de thèse permettent de détecter plusieurs classes de métabolites secondaires apolaires phytochimiques (figures 23 et 24) : terpènes, stérols, quinones et phénols, III.3. IDENTIFICATION DES COMPOSES Les deux méthodes chromatographiques

L. Deux-méthodes-chromatographiques-(-htgc-/ and N. Ms, MS) proposées ont permis de caractériser la majorité des métabolites secondaires apolaires identifiés dans les feuilles de C

W. Jones and A. Kinghorn, Extraction of plant secondary metabolites, Natural Products Isolation Methods in Biotechnology, vol.20, pp.323-351, 2005.

A. Kamboj, Analytical evaluation of herbal drugs Drug Discovery Research in Pharmacognosy, 2012.

Z. Yongyu, S. Shujun, D. Jianye, W. Wenyu, C. Huijuan et al., Quality Control Method for Herbal Medicine - Chemical Fingerprint Analysis, pp.171-194, 2011.
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C. Welch, Chemistry and pharmacology of Kinkéliba (Combretum micranthum), a west African medicinal plant. Ph D Graduate Program in Medicinal Chemistry, 2010.