Abstract : The research work presented in this thesis belongs to the fields of interactive applications generation and content personalization. This thesis proposes an MDA (Model Driven Architecture) approach, independent of the domain application, allowing the design and the semi-automatic generation of personalized content interactive applications. This generation relies on context information and the domain ontology. This approach implements two content personalization methods ; namely the forms auto-filling and the automatic queries enrichment. To achieve this goal, we developed the technical solution allowing the design, the models transformations as well as the generation of the final HCI (Human-Computer Interface).