15 2.2.1 Evènements favorisant un blocage de différenciation 16 a. Exemple des LAM à Core Binfing Factor (CBF) 16 b. Autres anomalies responsables d'un blocage de différentiation 17 2.2.2 Evènements conférant aux cellules un avantage prolifératif 18 a, p.24 ,
29 c. Substrats impliqués dans l'autophagie, 27 b. eIF4E Binding Proteins (4E-BPs) et rôle de mTOR dans la synthèse, p.37 ,
42 3.4.1 Rétrocontrôle négatif de mTORC1 sur la voie PI3K, ., p.43 ,
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