H. Merzendorfer and L. Zimoch, Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases, Journal of Experimental Biology, vol.206, issue.24, pp.4393-412, 2003.
DOI : 10.1242/jeb.00709

B. D. Lindahl, Spatial separation of litter decomposition and mycorrhizal nitrogen uptake in a boreal forest, New Phytologist, vol.151, issue.3, pp.611-631, 2007.
DOI : 10.1111/j.1469-8137.2006.01936.x

J. M. Barea, Microbial co-operation in the rhizosphere, Journal of Experimental Botany, vol.56, issue.417, pp.1761-78, 2005.
DOI : 10.1093/jxb/eri197

D. N. Quang, T. Hashimoto, and Y. Asakawa, Inedible mushrooms: a good source of biologically active substances, The Chemical Record, vol.56, issue.2, pp.79-99, 2006.
DOI : 10.1002/tcr.20074

J. Frisvad, Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium, STUDIES IN MYCOLOGY, vol.49, pp.201-241, 2004.

D. Vieira and F. , Biological activities of the fermentation extract of the endophytic fungus Alfernaria alternata isolated from Coffea arabica L, p.45, 2009.

J. K. Liu, Secondary metabolites from higher fungi in China and their biological activity, Drug Discov Ther, vol.1, issue.2, pp.94-103, 2007.

D. L. Hawksworth, The fungal dimension of biodiversity: magnitude, significance, and conservation, Mycological Research, vol.95, issue.6, pp.641-655, 1991.
DOI : 10.1016/S0953-7562(09)80810-1

A. J. Whalley and R. L. Edwards, The Xylariaceae: A Case Study in Biological and Chemical Diversity, 1999.

D. S. Hibbett, A higher-level phylogenetic classification of the Fungi, Mycological Research, vol.111, issue.5, pp.509-556, 2007.
DOI : 10.1016/j.mycres.2007.03.004

P. M. Kirk, Dictionary of the Fungi 10th ed. Wallingford: CABI, p.55, 2008.

Y. M. Ju and R. J. , A Revision of the Genus Hypoxylon, 1996.

D. Lonsdale, M. Pautasso, and O. Holdenrieder, Wood-decaying fungi in the forest: conservation needs and management options, European Journal of Forest Research, vol.172, issue.Suppl 6, pp.1-22, 2008.
DOI : 10.1007/s10342-007-0182-6

A. Y. Rossman and M. E. Palm-hernandez, Systematics of Plant Pathogenic Fungi: Why It Matters, Plant Disease, vol.92, issue.10, pp.92-1376, 2008.
DOI : 10.1094/PDIS-92-10-1376

A. M. Tang, R. Jeewon, and K. D. Hyde, A re-evaluation of the evolutionary relationships within the Xylariaceae based on ribosomal and protein-coding gene sequences, Fungal divers, vol.34, pp.127-155, 2009.

J. D. Rogers, Xylaria bulbosa, Xylaria curta, and Xylaria longipes in Continental United States, Mycologia, vol.75, issue.3, pp.457-467, 1983.
DOI : 10.2307/3792687

M. Stadler, J. Fournier, A. Granmo, and E. Beltran-tejera, The "red Hypoxylons" of the temperate and subtropical Northern hemisphere, North American Fungi, vol.3, issue.7, pp.73-125, 2008.
DOI : 10.2509/naf2008.003.0075

L. Boddy and A. D. Rayner, ORIGINS OF DECAY IN LIVING DECIDUOUS TREES: THE ROLE OF MOISTURE CONTENT AND A RE-APPRAISAL OF THE EXPANDED CONCEPT OF TREE DECAY, New Phytologist, vol.68, issue.4, pp.623-641, 1983.
DOI : 10.1146/annurev.py.11.090173.001213

S. B. Pointing, M. M. Parungao, and K. D. Hyde, Production of wood-decay enzymes, mass loss and lignin solubilization in wood by tropical Xylariaceae, Mycological Research, vol.107, issue.2, pp.231-236, 2003.
DOI : 10.1017/S0953756203007329

S. B. Pointing, Screening of basidiomycetes and xylariaceous fungi for lignin peroxidase and laccase gene-specific sequences, Mycological Research, vol.109, issue.1, pp.115-139, 2005.
DOI : 10.1017/S0953756204001376

S. Shary, S. A. Ralph, and K. E. Hammel, New Insights into the Ligninolytic Capability of a Wood Decay Ascomycete, Applied and Environmental Microbiology, vol.73, issue.20, pp.73-6691, 2007.
DOI : 10.1128/AEM.01361-07

E. C. Davis, Endophytic Xylaria (Xylariaceae) among liverworts and angiosperms: phylogenetics, distribution, and symbiosis, American Journal of Botany, vol.90, issue.11, pp.90-1661, 2003.
DOI : 10.3732/ajb.90.11.1661

P. Müller and . Und-ascomyceten, Untersuchungen aus Brasilien, A monograph of the world species of Hypoxylon Athens, 1901.

A. J. Whalley, Numerical taxonomy of some species of hypoxylon, Mycopathologia, vol.64, issue.3, pp.155-161, 1976.
DOI : 10.1007/BF00627877

M. Stadler and H. Wollweber, Secondary metabolite profiling, genetic fingerprints and taxonomy of Daldinia and allies, Mycotaxon, vol.77, pp.379-429, 2001.

M. Stadler, Changes in secondary metabolism during stromatal ontogeny of Hypoxylon fragiforme, Mycological Research, vol.110, issue.7, pp.811-831, 2006.
DOI : 10.1016/j.mycres.2006.03.013

M. Stadler, Y. M. Ju, and J. D. Rogers, Chemotaxonomy of Entonaema, Rhopalostroma and other Xylariaceae, Mycological Research, vol.108, issue.3, pp.239-56, 2004.
DOI : 10.1017/S0953756204009347

M. Stadler and N. P. Keller, Paradigm shifts in fungal secondary metabolite research, Mycological Research, vol.112, issue.2, pp.127-157, 2008.
DOI : 10.1016/j.mycres.2007.12.002

M. Stadler and J. Fournier, Pigment chemistry, taxonomy and phylogeny of the Hypoxyloideae (Xylariaceae), Revista Iberoamericana de Micolog??a, vol.23, issue.3, pp.160-70, 2006.
DOI : 10.1016/S1130-1406(06)70037-7

. Stadler, Molecular chemotaxonomy of Daldinia and other Xylariaceae, Mycological Research, vol.105, issue.10, pp.1191-1205, 2001.
DOI : 10.1016/S0953-7562(08)61990-5

N. Radulovic, Novi azafiloni, steroidi i terfenili iz gljiva Creosphearia sassafras, Hypoxylon Multiforme i Theleophora terrestris. Doctoral disertation, 2006.

V. Hellwig, Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling, Mycological Progress, vol.51, issue.Suppl.1, pp.39-54, 2005.
DOI : 10.1007/s11557-006-0108-6

H. M. Hsieh, Y. M. Ju, and J. D. Rogers, and closely related genera, Mycologia, vol.97, issue.4, pp.844-65, 2005.
DOI : 10.1080/15572536.2006.11832776

J. Webster and R. W. Weber, Teaching Techniques for Mycology: 23. Eclosion of Hypoxylon fragiforme ascospores as a prelude to germination, Mycologist, vol.18, issue.4, pp.18-170, 2004.
DOI : 10.1017/S0269915X04004070

V. Betina, Structure-activity relationships among mycotoxins, Chemico-Biological Interactions, vol.71, issue.2-3, pp.105-146, 1989.
DOI : 10.1016/0009-2797(89)90030-6

S. Brase, Chemistry and Biology of Mycotoxins and Related Fungal Metabolites, Chemical Reviews, vol.109, issue.9, pp.3903-90, 2009.
DOI : 10.1021/cr050001f

. Chang, )-Concentricolide, The Journal of Organic Chemistry, vol.76, issue.10, 2011.
DOI : 10.1021/jo2004132

. Fange, ChemInform Abstract: First Synthesis of Racemic Concentricolide, an anti-HIV-1 Agent Isolated from the Fungus Daldinia concentrica., ChemInform, vol.78, issue.51, pp.782107-2113, 2009.
DOI : 10.1002/chin.200951208

H. Nagasawa, Apoptosis induction in HCT116 cells by cytochalasins isolated from the fungus Daldinia vernicosa, Phytomedicine, vol.6, issue.6, pp.403-412, 2000.
DOI : 10.1016/S0944-7113(00)80067-7

D. N. Quang, Cyclic azaphilones daldinins E and F from the ascomycete fungus Hypoxylon fuscum (Xylariaceae), Phytochemistry, vol.65, issue.4, pp.469-73, 2004.
DOI : 10.1016/j.phytochem.2003.09.022

. Gil, Progress in the Chemistry of Organic Natural Products, p.51, 1987.

D. N. Quang, Cohaerins A and B, azaphilones from the fungus Hypoxylon cohaerens, and comparison of HPLC-based metabolite profiles in Hypoxylon sect, Annulata. Phytochemistry, issue.7, pp.66-797, 2005.

D. Ngoc and Q. , Sassafrins A-D, new antimicrobial azaphilones from the fungus Creosphaeria sassafras, Tetrahedron, issue.7, pp.61-1743, 2005.

D. N. Quang, Inhibition of Nitric Oxide Production in RAW 264.7 Cells by Azaphilones from Xylariaceous Fungi, Biological & Pharmaceutical Bulletin, vol.29, issue.1, pp.34-41, 2006.
DOI : 10.1248/bpb.29.34

. Quang, Cohaerins C-F, four azaphilones from the xylariaceous fungus Annulohypoxylon cohaerens, Tetrahedron, issue.26, pp.62-6349, 2006.

T. Kimura, Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp, Bioorg Med Chem, issue.8, pp.16-4594, 2008.

X. Zou, Helotialins A?C, Anti-HIV Metabolites from a Helotialean Ascomycete, Chinese J. Nat. Med, issue.7, pp.140-144, 2009.

. Powell, Survey of the chemistry of the azaphilones to that date. Chemical Society Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum, FEMS Microbiol Lett, issue.2, pp.252-309, 1956.

D. A. Hopwood, The Leeuwenhoek lecture Towards an understanding of gene switching in Streptomyces, the basis of sporulation and antibiotic production, Proc R Soc Lond B Biol Sci, pp.235-121, 1279.

R. A. Maplestone, M. J. Stone, and D. H. Williams, The evolutionary role of secondary metabolites ??? a review, Gene, vol.115, issue.1-2, pp.1-2, 1992.
DOI : 10.1016/0378-1119(92)90553-2

J. D. Bu-'lock, Intermediary metabolism and antibiotic synthesis, Adv Appl Microbiol, issue.3, pp.293-342, 1961.

J. Sekiguchi and G. M. Gaucher, Conidiogenesis and secondary metabolism in Penicillium urticae

A. M. Calvo, Relationship between Secondary Metabolism and Fungal Development, Microbiology and Molecular Biology Reviews, vol.66, issue.3, pp.447-59, 2002.
DOI : 10.1128/MMBR.66.3.447-459.2002

J. Kronstad, Signaling via cAMP in fungi: interconnections with mitogen-activated protein kinase pathways, Archives of Microbiology, vol.170, issue.6, pp.395-404, 1998.
DOI : 10.1007/s002030050659

J. H. Yu and N. Keller, Regulation of Secondary Metabolism in Filamentous Fungi, Annual Review of Phytopathology, vol.43, issue.1, pp.437-58, 2005.
DOI : 10.1146/annurev.phyto.43.040204.140214

E. K. Shwab and N. P. Keller, Regulation of secondary metabolite production in filamentous ascomycetes, Mycological Research, vol.112, issue.2, pp.225-255, 2008.
DOI : 10.1016/j.mycres.2007.08.021

N. P. Keller, G. Turner, and J. W. Bennett, Fungal secondary metabolism ??? from biochemistry to genomics, Nature Reviews Microbiology, vol.70, issue.12, pp.937-984, 2005.
DOI : 10.1038/nrmicro1286

D. W. Brown, Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans., Proceedings of the National Academy of Sciences, vol.93, issue.4, pp.1418-1440, 1996.
DOI : 10.1073/pnas.93.4.1418

M. Fernandes, N. P. Keller, and T. H. Adams, Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis, Molecular Microbiology, vol.81, issue.6, pp.28-1355, 1998.
DOI : 10.1007/s002940050084

D. Hoffmeister and N. P. Keller, Natural products of filamentous fungi: enzymes, genes, and their regulation, Nat. Prod. Rep., vol.56, issue.69, pp.393-416, 2007.
DOI : 10.1039/B603084J

. Osmanova, Azaphilones: a class of fungal metabolites with diverse biological activities, Phytochemistry Reviews, vol.7, issue.2, pp.315-342, 2010.
DOI : 10.1007/s11101-010-9171-3

E. Mylonakis, A. Casadevall, and F. M. Ausubel, Exploiting Amoeboid and Non-Vertebrate Animal Model Systems to Study the Virulence of Human Pathogenic Fungi, PLoS Pathogens, vol.112, issue.7, p.101, 2007.
DOI : 0021-9738(2003)112[1080:IOAAAR]2.0.CO;2

E. M. Fox and B. J. Howlett, Secondary metabolism: regulation and role in fungal biology, Current Opinion in Microbiology, vol.11, issue.6, pp.481-487, 2008.
DOI : 10.1016/j.mib.2008.10.007

. Stadler, Chemotaxonomy of the Xylariaceae and remarkable bioactive compounds from Xylariales and their associated asexual stages, Phytochemistry, issue.9, 2005.

J. Ying, Icons of medicinal fungi from China, 1987.

H. P. Molitoris, Pilze in Medizin, Folklore und Religion, Feddes Repertorium, vol.113, issue.1-2, pp.165-182, 2002.
DOI : 10.1002/1522-239X(200205)113:1/2%3C165::AID-FEDR165%3E3.0.CO;2-M

C. Hobbs, Medicinal mushrooms: an exploration of tradition, health and culture. Botanica press Pigments of fungi (Macromycetes), Fortschr Chem Org Naturst, issue.51, pp.1-317, 1987.

W. Steglich, B. Fugmann, and L. S. , Encyclopedia natural products Thieme Verlag Mikrobialna produkcia farbnych azaphilonovych metabolitov, Chem Listy, vol.94, pp.105-110, 2000.

J. Dong, New nematicidal azaphilones from the aquatic fungus Pseudohalonectria adversaria Microbiol Lett, pp.65-74, 2006.

M. Stadler, Novel Bioactive Azaphilones from Fruit Bodies and Mycelial Cultures of the Ascomycete Bulgaria inquinans (Fr.) Natural Product Letters, pp.7-14, 1995.

. Akihisa, Anti-Tumor-Initiating Effects of Monascin, an Azaphilonoid Pigment from the Extract ofMonascus pilosus Fermented Rice (Red-Mold Rice), Chemistry & Biodiversity, vol.51, issue.10, pp.1305-1314, 2005.
DOI : 10.1002/cbdv.200590101

S. J. Duncan, sp., Journal of the American Chemical Society, vol.123, issue.4, pp.554-560, 2001.
DOI : 10.1021/ja002940p

J. Zhu, A. R. Germain, and J. A. Porco, Synthesis of Azaphilones and Related Molecules by Employing Cycloisomerization of o-Alkynylbenzaldehydes., ChemInform, vol.43, issue.28, pp.43-1239, 2004.
DOI : 10.1002/chin.200428221

. Park, Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum. FEMS microbiology letters, pp.309-313, 2005.

. Hajjaj, Medium-chain fatty acids affect citrinin production in the filamentous fungus Monascus tuber, p.66, 2000.

. Velisek, Biosynthesis of Food Constituents: Natural Pigments. Part 2 -a Review, Czech journal of food sciences, vol.26, issue.2, pp.73-98, 2008.

J. Veli?ek, C. K. Turner, W. B. Aldridge, and D. C. , Pigments of higher fungi -a review Fungal metabolites, Czech Journal of Food Science, vol.87, 1971.

W. Graf, Biosynthesis of the Cytochalasans. Part III.13C-NMR. of cytochalasin B (phomin) and cytochalasin D. Incorporation of [1-13C]- and [2-13C]-sodium acetate, Helvetica Chimica Acta, vol.56, issue.6, pp.57-1801, 1974.
DOI : 10.1002/hlca.19740570630

G. R. Birchall, The chemistry of fungi. Part LX. The synthesis of tetrahydrosclerotioramine, tetrahydrosclerotoquinone, and tetrahydrosclerotiorin, Journal of the Chemical Society C: Organic, pp.3559-3566, 1971.
DOI : 10.1039/j39710003559

R. Chong, R. R. King, and W. B. Whalley, The synthesis of sclerotiorin and of an analogue of rotiorin, Journal of the Chemical Society D: Chemical Communications, vol.24, issue.24, pp.1512-1513, 1969.
DOI : 10.1039/c29690001512

T. Suzuki, -isochromene-6,8-dione and its analogues, Journal of Heterocyclic Chemistry, vol.75, issue.6, pp.38-1409, 2001.
DOI : 10.1002/jhet.5570380625
URL : https://hal.archives-ouvertes.fr/in2p3-00409176

J. Zhu, Synthesis of the Azaphilones Using Copper-Mediated Enantioselective Oxidative Dearomatization, Journal of the American Chemical Society, vol.127, issue.26, pp.9342-9343, 2005.
DOI : 10.1021/ja052049g

J. Zhu and J. A. Porco, Asymmetric Syntheses of (â?')-Mitorubrin and Related Azaphilone Natural Products, Organic Letters, issue.822, pp.5169-5171, 2006.

W. Wei and Z. Yao, Synthesis Studies toward Chloroazaphilone and Vinylogous ??-Pyridones:?? Two Common Natural Product Core Structures, The Journal of Organic Chemistry, vol.70, issue.12, pp.70-4585, 2005.
DOI : 10.1021/jo050414g

. Juzlova, Secondary metabolites of the fungus Monascus : a review, Journal of Industrial Microbiology Biotechnology, vol.16, issue.3, 1996.

. Frisvad, Analysis and screening for mycotoxins and other secondary metabolites in fungal cultures by thin-layer chromatography and high-performance liquid chromatography, Archives of Environmental Contamination and Toxicology, vol.3, issue.3, pp.331-335, 1989.
DOI : 10.1007/BF01062357

C. J. Frisvad, High-performance liquid chromatographic determination of profiles of mycotoxines and other secondary metabolites, Journal of Chromatography A, vol.392, pp.333-347, 1987.
DOI : 10.1016/S0021-9673(01)94277-3

C. J. Frisvad, The use of high-performance liquid chromatography and diode array detection in fungal chemotaxonomy based on profiles of secondary metabolites, Botanical Journal of the Linnean Society, vol.99, issue.1, pp.81-95, 1989.
DOI : 10.1111/j.1095-8339.1989.tb00393.x

. Nielsen, Fungal metabolite screening: database of 474 mycotoxins and fungal metabolites for dereplication by standardised liquid chromatography???UV???mass spectrometry methodology, Journal of Chromatography A, vol.1002, issue.1-2, pp.509-512, 2010.
DOI : 10.1016/S0021-9673(03)00490-4

K. F. Nielsen, Chemical Identification of Fungi, p.6, 2004.
DOI : 10.1201/9780203913369.ch2

. Smedsgaard, Using direct electrospray mass spectrometry in taxonomy and secondary metabolite profiling of crude fungal extracts, Journal of Microbiological Methods, vol.25, issue.1, pp.5-17, 1996.
DOI : 10.1016/0167-7012(95)00073-9

J. Smedsgaard, T. Penicillia-smedsgaard, J. R. Frisvad, and J. C. , Terverticillate penicillia studied by direct electrospray mass spectrometric profiling of crude extracts. I. Chemosystematics, Biochemical Systematics and Ecology, vol.25, issue.1, pp.65-71, 1997.
DOI : 10.1016/S0305-1978(96)00088-9

J. Smedsgaard, Classification of terverticillate Penicillia by electrospray mass spectrometric profiling, Studies in Mycology, vol.49, pp.243-251, 2004.

J. C. Frisvad and S. R. , Polyphasic taxonomy of Penicillium subgenus Penicillium. A guide to identification of the food and air-borne terverticillate Penicillia and their mycotoxins, Studies in Mycology, issue.173, pp.49-50, 2004.

. Bitzer, Accelerated Dereplication of Natural Products, Supported by Reference Libraries, CHIMIA International Journal for Chemistry, vol.61, issue.6, pp.61-332, 2007.
DOI : 10.2533/chimia.2007.332

. Novakova, A review of current trends and advances in modern bio-analytical methods: Chromatography and sample preparation, Analytica Chimica Acta, vol.656, issue.1-2, pp.8-35, 2009.
DOI : 10.1016/j.aca.2009.10.004

H. Kataoka, New trends in sample preparation for clinical and pharmaceutical analysis, TrAC Trends in Analytical Chemistry, vol.22, issue.4, pp.232-244, 2003.
DOI : 10.1016/S0165-9936(03)00402-3

. Herrera, Ultrasound-assisted extraction of phenolic compounds from strawberries prior to liquid chromatographic separation and photodiode array ultraviolet detection, Journal of Chromatography A, vol.1100, issue.1, pp.1100-1101, 2005.
DOI : 10.1016/j.chroma.2005.09.021

I. D. Wilson, HPLC-MS-based methods for the study of metabonomics, Journal of Chromatography B, vol.817, issue.1, pp.67-76, 2005.
DOI : 10.1016/j.jchromb.2004.07.045

C. C. Leandro, Comparison of ultra-performance liquid chromatography and high-performance liquid chromatography for the determination of priority pesticides in baby foods by tandem quadrupole mass spectrometry, Journal of Chromatography A, vol.1103, issue.1, pp.94-101, 2006.
DOI : 10.1016/j.chroma.2005.10.077

R. P. Scott, Chromatographic detectors, Design, Function and Operation, Chromatographic Science Series, vol.73, p.180

G. E. Martin and R. C. Crouch, Inverse-Detected Two-Dimensional Nmr Methods: Applications in Natural Products Chemistry, Journal of Natural Products, vol.54, issue.1, pp.1-70, 1991.
DOI : 10.1021/np50073a001

M. I. Atta-ur-rahman and . Choudhary, Solving Problems with NMR Spectroscopy, 1996.

V. Exarchou, LC-NMR coupling technology: recent advancements and applications in natural products analysis. Magnetic Resonance Chemistry, pp.681-688, 2005.

C. G. Huber and H. Oberacher, Analysis of nucleic acids by on-line liquid chromatography-Mass spectrometry, Mass Spectrometry Reviews, vol.88, issue.5, pp.310-353, 2001.
DOI : 10.1002/mas.10011

E. N. Il-'ina and V. M. Govorun, Mass spectrometry of nucleic acids in molecular medicine, Bioorg Khim, vol.35, issue.2, pp.149-64, 2009.

G. Mamone, Analysis of food proteins and peptides by mass spectrometry-based techniques, Journal of Chromatography A, vol.1216, issue.43, pp.1216-7130, 2009.
DOI : 10.1016/j.chroma.2009.07.052

J. A. Rodrigues, Mass Spectrometry of Carbohydrates: Newer Aspects, Adv Carbohydr Chem Biochem, vol.61, pp.59-141, 2007.
DOI : 10.1016/S0065-2318(07)61003-8

A. N. Hoofnagle and J. W. Heinecke, Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins, The Journal of Lipid Research, vol.50, issue.10, pp.50-1967, 2009.
DOI : 10.1194/jlr.R900015-JLR200

. Tanaka, Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry, Rapid Communications in Mass Spectrometry, vol.12, issue.8, pp.60-2299, 1988.
DOI : 10.1002/rcm.1290020802

G. Buchi, J. D. White, and G. N. Wogan, The Structures of Mitorubrin and Mitorubrinol, Journal of the American Chemical Society, vol.87, issue.15, pp.3484-3489, 1965.
DOI : 10.1021/ja01093a036

J. S. Gaskell and E. , Electrospray: Principles and Practice, Journal of Mass Spectrometry, vol.32, issue.7, pp.677-688, 1997.
DOI : 10.1002/(SICI)1096-9888(199707)32:7<677::AID-JMS536>3.0.CO;2-G

C. M. Whitehouse, Electrospray interface for liquid chromatographs and mass spectrometers, Analytical Chemistry, vol.57, issue.3, pp.675-684, 1985.
DOI : 10.1021/ac00280a023

P. Kebarle and L. Tang, From ions in solution to ions in the gas phase - the mechanism of electrospray mass spectrometry, Analytical Chemistry, vol.65, issue.22, pp.65-972, 1993.
DOI : 10.1021/ac00070a001

M. S. Wilm and M. Mann, Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?, International Journal of Mass Spectrometry and Ion Processes, vol.136, issue.2-3, pp.136-167, 1994.
DOI : 10.1016/0168-1176(94)04024-9

B. J. Fenn, Ion formation from charged droplets: roles of geometry, energy, and time, Journal of the American Society for Mass Spectrometry, vol.4, issue.7, pp.524-535, 1993.
DOI : 10.1016/1044-0305(93)85014-O

M. M. Dole, Molecular Beams of Macroions, The Journal of Chemical Physics, vol.49, issue.5, p.9, 1968.
DOI : 10.1063/1.1670391

J. V. Iribarne and B. A. Thomson, On the evaporation of small ions from charged droplets, The Journal of Chemical Physics, vol.64, issue.6, pp.2287-2294, 1976.
DOI : 10.1063/1.432536

R. Cole, Electrospray and MALDI mass spectrometry : fundamentals, instrumentation, practicalities, and biological applications, p.9, 2010.
DOI : 10.1002/9780470588901

E. De-rijke, Analytical separation and detection methods for flavonoids, Journal of Chromatography A, vol.1112, issue.1-2, pp.31-63, 2006.
DOI : 10.1016/j.chroma.2006.01.019

E. D. Hoffmann, . Ltd, and . Chichester, Mass spectrometry Principles and applications, pp.33-39, 2002.

S. Kazuno, Mass spectrometric identification and quantification of glycosyl flavonoids, including dihydrochalcones with neutral loss scan mode, Analytical Biochemistry, vol.347, issue.2, pp.182-92, 2005.
DOI : 10.1016/j.ab.2005.09.020

E. Hvattum and D. Ekeberg, Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionization tandem quadrupole mass spectrometry, Journal of Mass Spectrometry, vol.10, issue.1, pp.43-52, 2003.
DOI : 10.1002/jms.398

P. Longevialle, Ion-neutral complexes in the unimolecular reactivity of organic cations in the gas phase, Mass Spectrometry Reviews, vol.27, issue.3, pp.157-192, 1992.
DOI : 10.1002/mas.1280110302

P. Longevialle and R. Botter, Electron impact mass spectra of bifunctional steroids. The interaction between ionic and neutral fragments derived from the same parent ion. Organic Mass Spectrometry, pp.1-8, 1983.

P. Longevialle and R. Botter, Evidence for intramolecular interaction between ionic and neutral fragments in the mass spectrometer, Journal of the Chemical Society, Chemical Communications, vol.17, issue.17, pp.823-825, 1980.
DOI : 10.1039/c39800000823

R. D. Bowen, R. G. Cooks, J. T. Koskinen, and P. D. Thomas, Reactions of isolated organic ions Alkene loss from the immonium ions CH3CH[double bond, length half m-dash]N+HC2H5 and CH3CH[double bond, length half m-dash]N+HC3H7 The kinetic method of making thermochemical determinations, Journal of the Chemical Society, Perkin Transactions J mass spectrom, vol.2, issue.342, pp.913-918, 1989.

R. E. Jianhua, G. Patel, and . Chirag, Determination of the gas-phase acidity of methylthioacetic acid-using the cooks' kinetic method, J Am Soc Mass Spectrom, vol.16, issue.4, pp.535-541, 2005.

D. Hunt, C. Mcewen, and R. Upham, Determination of active hydrogen in organic compounds by chemical ionization mass spectrometry, Analytical Chemistry, vol.44, issue.7, pp.44-1292, 1972.
DOI : 10.1021/ac60315a055

R. Mohamed, Mass spectral characterization of ergot alkaloids by electrospray ionization, hydrogen/deuterium exchange, and multiple stage mass spectrometry: usefulness of precursor ion scan experiments, Rapid Communications in Mass Spectrometry, vol.13, issue.19, pp.20-2787, 2006.
DOI : 10.1002/rcm.2648

M. E. Hemling, Gas phase hydrogen / deuterium exchange in electrospray ionization mass spectrometry as a practical tool for structure elucidation, Journal of the American Society for Mass Spectrometry, vol.20, issue.5, pp.434-442, 1994.
DOI : 10.1016/1044-0305(94)85059-3

Z. Takàts, G. Schlosser, and K. Vékey, Hydrogen/deuterium exchange of electrosprayed ions in the atmospheric interface of a commercial triple???quadrupole mass spectrometer, International Journal of Mass Spectrometry, vol.228, issue.2-3, pp.729-741, 2003.
DOI : 10.1016/S1387-3806(03)00234-3

S. Campbell, Structural and Energetic Constraints on Gas Phase Hydrogen/Deuterium Exchange Reactions of Protonated Peptides with D2O, CD3OD, CD3CO2D, and ND3, Journal of the American Chemical Society, vol.116, issue.21, pp.116-9765, 1994.
DOI : 10.1021/ja00100a058

. Campbell, Deuterium Exchange Reactions as a Probe of Biomolecule Structure. Fundamental Studies of Gas Phase H/D Exchange Reactions of Protonated Glycine Oligomers with D2O, CD3OD, CD3CO2D, and ND3, Journal of the American Chemical Society, vol.117, issue.51, pp.12840-12854, 1995.
DOI : 10.1021/ja00156a023

D. F. Hunt and S. K. Sethi, Gas-phase ion/molecule isotope-exchange reactions: methodology for counting hydrogen atoms in specific organic structural environments by chemical ionization mass spectrometry, Journal of the American Chemical Society, vol.102, issue.23, pp.102-6953, 1980.
DOI : 10.1021/ja00543a009

E. Gard, Gas-phase hydrogen/deuterium exchange as a molecular probe for the interaction of methanol and protonated peptides, Journal of the American Society for Mass Spectrometry, vol.28, issue.7, pp.623-631, 1994.
DOI : 10.1016/1044-0305(94)85003-8

J. Ni and A. G. Harrison, Reactive collisions in quadrupole cells. 2. H/D exchange reactions of enolate ions with CH3od and C2H5OD, Journal of the American Society for Mass Spectrometry, vol.17, issue.8, pp.853-858, 1992.
DOI : 10.1016/1044-0305(92)80009-A

R. Asoka, Selective isotopic exchange of polyfunctional ions in tandem mass spectrometry : methodology, applications and mechanism. Organic mass spectrometry, pp.77-88, 1992.

J. B. Fenn, Electrospray ionization for mass spectrometry of large biomolecules, Science, vol.246, issue.4926, pp.64-71, 1989.
DOI : 10.1126/science.2675315

. Cech, Practical implications of some recent studies in electrospray ionization fundamentals, Mass Spectrometry Reviews, vol.52, issue.6, pp.362-387, 2001.
DOI : 10.1002/mas.10008

. Leinonen, Liquid chromatography/mass spectrometry in anabolic steroid analysis?optimization and comparison of three ionization techniques: electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization, Journal of Mass Spectrometry, vol.8, issue.7, pp.693-698, 2002.
DOI : 10.1002/jms.328

. Dams, Matrix effect in bio-analysis of illicit drugs with LC-MS/MS: Influence of ionization type, sample preparation, and biofluid, Journal of the American Society for Mass Spectrometry, vol.65, issue.11, pp.14-1290, 2003.
DOI : 10.1016/S1044-0305(03)00574-9

. Niessen, Matrix effects in quantitative pesticide analysis using liquid chromatography???mass spectrometry, Mass Spectrometry Reviews, vol.378, issue.6, pp.8818-99, 2006.
DOI : 10.1002/mas.20097

H. U. Qizhi, The orbitrap : a new mass spectrometer, J Mass Spectrom, vol.40, issue.4, pp.430-473, 2005.

L. L. Lopez, Automated strategies for obtaining standardized collisionally induced dissociation spectra on a benchtop ion trap mass spectrometer, Rapid Communications in Mass Spectrometry, vol.64, issue.8, pp.13-663, 1999.
DOI : 10.1002/(SICI)1097-0231(19990430)13:8<663::AID-RCM538>3.0.CO;2-H

S. Baumgarten, The Role of Water in Platinum-Catalyzed Cycloisomerization of 1,6-Enynes: A Combined Experimental and Theoretical Gas Phase Study, ChemCatChem, vol.76, issue.1, pp.138-143, 2009.
DOI : 10.1002/cctc.200900003

M. J. Frisch, Gaussian 09, Revision B.01, Gaussian 09, Revision B.01, 2009.

C. T. Lee and R. G. Parr, Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density, Physical Review B, vol.37, issue.2, pp.785-789, 1988.
DOI : 10.1103/PhysRevB.37.785

A. D. Becke, Density???functional thermochemistry. III. The role of exact exchange, The Journal of Chemical Physics, vol.98, issue.7, pp.98-5648, 1993.
DOI : 10.1063/1.464913

F. Weigend and R. Ahlrichs, Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy, Physical Chemistry Chemical Physics, vol.110, issue.16, pp.3297-3305, 2005.
DOI : 10.1039/b508541a

L. Svilar, Distinctive gas-phase fragmentation pathway of the mitorubramines, novel secondary metabolites from Hypoxylon fragiforme, Rapid Communication in Mass Spectrometry, p.2012

. Stadler, Identification of alkaloids and polyketides in an Actinomycete by high-performance liquid chromatography with mass spectrometric and UV???Visible detection, Journal of Chromatography A, vol.818, issue.2, pp.187-195, 1998.
DOI : 10.1016/S0021-9673(98)00548-2

L. Li, A New Azaphilone, Kasanosin C, from an Endophytic Talaromyces sp. T1BF, Molecules, vol.15, issue.6, pp.3993-3997, 2010.
DOI : 10.3390/molecules15063993

T. H. Morton, Ion-molecule complexes in unimolecular fragmentations of gaseous cations. Alkyl phenyl ether molecular ions, Journal of the American Chemical Society, vol.102, issue.5, pp.1596-1602, 1980.
DOI : 10.1021/ja00525a022

R. D. Bowen and D. H. Williams, Unimolecular reactions of isolated organic ions. The importance of ion-dipole interactions, Journal of the American Chemical Society, vol.102, issue.8, pp.102-2752, 1980.
DOI : 10.1021/ja00528a038

C. R. Moylan and J. I. Brauman, Mechanistic information from infrared multiple photon decomposition. The ethylisopropylamine proton-transfer system, Journal of the American Chemical Society, vol.107, issue.4, pp.761-765, 1985.
DOI : 10.1021/ja00290a004

Z. Garver-jm-fau-yang, Gas phase reactions of 1,3,5-triazine: proton transfer, hydride transfer, and anionic sigma-adduct formation, p.1260, 2011.

. Tutar, Bromination of an N-carbethoxy-7-aza-2,3-benzonorbornadiene and synthesis of N-carbethoxy-7-aza-2,3-dibromo-5,6-benzonorbornadiene: high temperature bromination. Part 14, Tetrahedron, vol.58, issue.44, pp.58-8979, 2002.
DOI : 10.1016/S0040-4020(02)01150-X

. Nikitina, First synthesis of 6-spiro[5-aza-2-oxatricyclo[6.2.1.0[3], pp.130-131, 2003.

V. Morlender, The role of hydrogen migration in the mechanism of alcohol elimination from MH+ ions of ethers upon chemical ionization, Journal of Mass Spectrometry, vol.32, issue.10, pp.32-1124, 1997.
DOI : 10.1002/(SICI)1096-9888(199711)32:10<1124::AID-JMS570>3.0.CO;2-7

. Kuzmenkov, Role of hydrogen migration in the mechanism of acetic acid elimination from MH+ ions of acetates on chemical ionization and collision-induced dissociation, Journal of Mass Spectrometry, vol.27, issue.8, pp.797-803, 1999.
DOI : 10.1002/(SICI)1096-9888(199908)34:8<797::AID-JMS834>3.0.CO;2-X

C. Fiolhais, F. Nogueira, M. A. Marques, S. Jongrungruangchok, P. Kittakoop et al., A Primer in Density Functional Theory. Lecture Notes in Physics Azaphilone Pigments From a Yellow Mutant of the Fungus Monascus kaoliang, Phytochemistry, vol.620, issue.65, p.2569, 2003.

M. Stadler, D. N. Quang, A. Tomita, T. Hashimoto, and Y. Asakawa, Changes in secondary metabolism during stromatal ontogeny of Hypoxylon fragiforme, Mycological Research, vol.110, issue.7, p.811, 2006.
DOI : 10.1016/j.mycres.2006.03.013

D. N. Quang, T. Hashimoto, M. Tanaka, M. Stadler, and Y. Asakawa, Cyclic azaphilones daldinins E and F from the ascomycete fungus Hypoxylon fuscum (Xylariaceae), Phytochemistry, vol.65, issue.4, p.469, 2004.
DOI : 10.1016/j.phytochem.2003.09.022

L. Svilar, High-resolution mass spectrometry and hydrogen/deuterium exchange study of mitorubrin azaphilones and nitrogenized analogues, Journal of Mass Spectrometry, vol.117, issue.8, pp.969-977, 2012.
DOI : 10.1002/jms.3044

D. N. Quang, T. Hashimoto, and Y. Asakawa, Inedible mushrooms: a good source of biologically active substances, The Chemical Record, vol.56, issue.2, p.79, 2006.
DOI : 10.1002/tcr.20074

M. Stadler and N. Keller, Paradigm shifts in fungal secondary metabolite research, Mycological Research, vol.112, issue.2, p.127, 2008.
DOI : 10.1016/j.mycres.2007.12.002

J. C. Frisvad, B. Andersen, and U. Thrane, The use of secondary metabolite profiling in chemotaxonomy of filamentous fungi, Mycological Research, vol.112, issue.2, p.231, 2008.
DOI : 10.1016/j.mycres.2007.08.018

L. Wu, D. Liu, and A. Kord, Gas-phase Meerwein reaction of epoxides with protonated acetonitrile generated by atmospheric pressure ionizations, Journal of the American Society for Mass Spectrometry, vol.1217, issue.10, p.1802, 2010.
DOI : 10.1016/j.jasms.2010.06.017

A. Germain, D. Bruggemeyer, J. Zhu, C. Genet, P. O-'brien et al., -Methylsclerotiorinamine Utilizing (+)-Sparteine Surrogates in Copper-Mediated Oxidative Dearomatization, The Journal of Organic Chemistry, vol.76, issue.8, pp.76-2577, 2011.
DOI : 10.1021/jo102448n
URL : https://hal.archives-ouvertes.fr/hal-00309497

N. Osmanova, W. Schultze, and N. Ayoub, Azaphilones: a class of fungal metabolites with diverse biological activities, Phytochemistry Reviews, vol.7, issue.2, p.315, 2010.
DOI : 10.1007/s11101-010-9171-3

V. Hellwig, Y. M. Ju, J. D. Rogers, J. Fournier, and M. Stadler, Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling, Mycological Progress, vol.51, issue.Suppl.1, 2005.
DOI : 10.1007/s11557-006-0108-6

J. Bitzer, B. Kopcke, M. Stadler, V. Hellwig, Y. M. Ju et al., Accelerated Dereplication of Natural products, Chimia, pp.61-332, 2007.

M. Stadler and H. Wollweber, Secondary Metabolite Profiles, Genetic Fingerprints and Taxonomy of Daldinia and Allies, Mycotaxon, vol.77, p.379, 2001.

J. Zhu, A. Germain, and J. Porco, Synthesis of Azaphilones and Related Molecules by Employing Cycloisomerization of o-alkynylbenzaldehide

L. Musso, S. Dallavalle, L. Merlini, A. Bava, G. Nasini et al., Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors, Bioorganic & Medicinal Chemistry, vol.18, issue.16, p.6031, 2010.
DOI : 10.1016/j.bmc.2010.06.068

A. Ranasinghe, G. Cooks, and S. Sethi, Selective isotopic exchange of polyfimctional ions in tandem mass spectrometry: Methodology, applications and mechanism, Organic Mass Spectrometry, vol.38, issue.2, p.77, 1992.
DOI : 10.1002/oms.1210270203

J. Ni and A. Harrison, Reactive collisions in quadrupole cells. 2. H/D exchange reactions of enolate ions with CH3od and C2H5OD, Journal of the American Society for Mass Spectrometry, vol.17, issue.8
DOI : 10.1016/1044-0305(92)80009-A

M. Hemling, J. Conboy, M. Bean, M. Mentzer, and S. Carr, Gas phase hydrogen / deuterium exchange in electrospray ionization mass spectrometry as a practical tool for structure elucidation, Journal of the American Society for Mass Spectrometry, vol.20, issue.5, p.434, 1994.
DOI : 10.1016/1044-0305(94)85059-3

S. Campbell, M. Rodgers, E. Marzluff, and J. Beauchamp, Structural and Energetic Constraints on Gas Phase Hydrogen/Deuterium Exchange Reactions of Protonated Peptides with D2O, CD3OD, CD3CO2D, and ND3, Journal of the American Chemical Society, vol.116, issue.21, p.9765, 1994.
DOI : 10.1021/ja00100a058

Q. Hu, R. Noll, H. Li, A. Makarov, M. Hardman et al., The Orbitrap: a new mass spectrometer, Journal of Mass Spectrometry, vol.15, issue.57, pp.40-430, 2005.
DOI : 10.1002/jms.856

L. Lopez, P. Tiller, M. Senko, and J. Schwartz, Automated strategies for obtaining standardized collisionally induced dissociation spectra on a benchtop ion trap mass spectrometer, Rapid Communications in Mass Spectrometry, vol.64, issue.8, p.663, 1999.
DOI : 10.1002/(SICI)1097-0231(19990430)13:8<663::AID-RCM538>3.0.CO;2-H

T. Liu, M. Belov, N. Jaitly, W. Qian, and R. Smith, Accurate Mass Measurements in Proteomics, Chem. Rev, issue.8, pp.107-3621, 2007.

R. Cole and J. Tabet, Stereospecific Ion-Molecule Reactions of Nucleophilic Gas-phase Reagents with Protonated Bifunctional Tetracyclic Terpene Epimers in the Triple Quadrupole Collision Cell, Journal of Mass Spectrometry, vol.32, issue.4
DOI : 10.1002/(SICI)1096-9888(199704)32:4<413::AID-JMS496>3.0.CO;2-C

S. Baumgarten, D. Lesage, V. Gandon, J. Goddard, M. Malacria et al., The Role of Water in Platinum-Catalyzed Cycloisomerization of 1,6-Enynes: A Combined Experimental and Theoretical Gas Phase Study, ChemCatChem, vol.76, issue.1, p.138, 2009.
DOI : 10.1002/cctc.200900003

S. Gronert, A. Fagin, and K. Okamoto, Stereoselectivity in the collision-activated reactions of gas phase salt complexes, Journal of the American Society for Mass Spectrometry, vol.6, issue.10, p.1509, 2004.
DOI : 10.1016/j.jasms.2004.07.013

M. Kinter and M. Bursey, Ion/molecule reactions of ammonia with two translationally excited C2H5O+ isomers, Journal of the American Chemical Society, vol.108, issue.8, p.1797, 1986.
DOI : 10.1021/ja00268a015

C. T. Lee, W. T. Yang, and R. G. Parr, Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density, Physical Review B, vol.37, issue.2, p.785, 1988.
DOI : 10.1103/PhysRevB.37.785

A. D. Becke, Density???functional thermochemistry. III. The role of exact exchange, The Journal of Chemical Physics, vol.98, issue.7, pp.98-5648, 1993.
DOI : 10.1063/1.464913

J. Garver, Z. Yang, S. Kato, W. Wren, K. Vogelhuber et al., Gas Phase Reactions of 1,3,5-Triazine: Proton Transfer, Hydride Transfer, and Anionic ??-Adduct Formation, Journal of The American Society for Mass Spectrometry, vol.2, issue.7, p.1260, 2011.
DOI : 10.1007/s13361-011-0133-9

S. Campbell, T. M. Rodgers, M. E. Marzluff, and J. L. Beauchamp, Deuterium Exchange Reactions as a Probe of Biomolecule Structure. Fundamental Studies of Gas Phase H/D Exchange Reactions of Protonated Glycine Oligomers with D2O, CD3OD, CD3CO2D, and ND3, Journal of the American Chemical Society, vol.117, issue.51, p.12840, 1995.
DOI : 10.1021/ja00156a023

F. Mitorubrin-azaphilones-by, J. Ms-&-h-/-d-exchange, . Mass, and . Spectrom, Ltd. wileyonlinelibrary.com/journal/jms * Correspondence to: V. Stankov-Jovanovic, University of Nis, Faculty of Science and Mathematics, Department of Chemistry , Visegradska33, 18000 Nis, Serbia. E-mail: sjvesna@pmf.ni.ac.rs ** Correspondence to, pp.969-977, 2012.

M. Stadler, H. Wollweber, A. Muhlbauer, T. Henkel, H. Wollweber et al., Secondary metabolite profiles, genetic fingerprints and taxonomy of Daldinia and allies, Mycotaxon, vol.77, p.379, 2001.

W. Steglich, M. Klaar, and W. Furtner, (+)-Mitorubrin derivatives from Hypoxylon fragiforme, Phytochemistry, vol.13, issue.12, p.2874, 1974.
DOI : 10.1016/0031-9422(74)80262-1

M. Stadler, J. Fournier, A. Granmo, and E. Beltran-tejera, The "red Hypoxylons" of the temperate and subtropical Northern hemisphere, North American Fungi, vol.3, p.73, 2008.
DOI : 10.2509/naf2008.003.0075

V. Hellwig, Y. Ju, J. D. Rogers, J. Fournier, and M. Stadler, Hypomiltin, a novel azaphilone from Hypoxylon hypomiltum, and chemotypes in Hypoxylon sect. Hypoxylon as inferred from analytical HPLC profiling. Mycolog, Macrocarpones, novel metabolites from stromata of Hypoxylon macrocarpum, and new evidence on the chemotaxonomy of Hypoxylon species. Mycolog, 2002.

M. Stadler, D. Quang, A. Tomita, T. Hashimoto, and Y. Asakawa, Changes in secondary metabolism during stromatal ontogeny of Hypoxylon fragiforme, Mycological Research, vol.110, issue.7, p.811, 2006.
DOI : 10.1016/j.mycres.2006.03.013

N. Arai, K. Shiomi, H. Tomoda, N. Tabata, D. Yang et al., Isochromophilones III -VI, Inhibitors of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium multicolor FO-3216., The Journal of Antibiotics, vol.48, issue.7, p.696, 1995.
DOI : 10.7164/antibiotics.48.696

T. Akihisa, H. Tokuda, K. Yasukawa, M. Ukiya, A. Kiyota et al., -Fermented Rice (Red-Mold Rice) and Their Chemopreventive Effects, Journal of Agricultural and Food Chemistry, vol.53, issue.3, p.562, 2005.
DOI : 10.1021/jf040199p
URL : https://hal.archives-ouvertes.fr/hal-00641566

H. Ge, W. Zhang, G. Ding, P. Saparpakorn, Y. Song et al., Chaetoglobins A and B, two unusual alkaloids from endophytic Chaetomium globosum culture, Chem. Commun, p.5978, 2008.

G. Buchi, J. White, and G. Wogan, The Structures of Mitorubrin and Mitorubrinol, Journal of the American Chemical Society, vol.87, issue.15, 1965.
DOI : 10.1021/ja01093a036

J. Bitzer, B. Kopcke, M. Stadler, V. Hellwig, Y. Ju et al., Accelerated Dereplication of Natural Products, Supported by Reference Libraries, CHIMIA International Journal for Chemistry, vol.61, issue.6, p.332, 2007.
DOI : 10.2533/chimia.2007.332

T. Larsen, J. Smedsgaard, K. Nielsen, M. Hansen, and J. Frisvad, Phenotypic taxonomy and metabolite profiling in microbial drug discovery, Natural Product Reports, vol.39, issue.1, p.672, 2005.
DOI : 10.1039/b404943h

Q. Hu, R. Noll, H. Li, A. Makarov, M. Hardman et al., The Orbitrap: a new mass spectrometer, Journal of Mass Spectrometry, vol.15, issue.57, pp.40-430, 2005.
DOI : 10.1002/jms.856

J. Olsen, L. De-godoy, G. Li, B. Macek, P. Mortensen et al., Parts per Million Mass Accuracy on an Orbitrap Mass Spectrometer via Lock Mass Injection into a C-trap, Molecular & Cellular Proteomics, vol.4, issue.12, p.12, 2011.
DOI : 10.1074/mcp.T500030-MCP200

A. Tutara and M. Balci, Bromination of an N-carbethoxy-7-aza-2,3-benzonorbornadiene and synthesis of N-carbethoxy-7-aza-2,3-dibromo-5,6-benzonorbornadiene: high temperature bromination. Part 14, Tetrahedron, vol.58, issue.44, pp.58-8979, 2002.
DOI : 10.1016/S0040-4020(02)01150-X

E. Nikitina, A. Safronova, A. Varlamov, F. Zubkov, G. Aleksandrov et al., First synthesis of 6-spiro [5-aza-2-oxatricyclo[6.2.1.03,9]undec-3-ene-6,1'-cyclo- hexane], Chem. Heterocycl. Compd, pp.39-130, 2003.

N. Morlender-vais and A. Mandelbaum, The role of hydrogen migration in the mechanism of alcohol elimination from MH+ ions of ethers upon chemical ionization, Journal of Mass Spectrometry, vol.32, issue.10, pp.31-1124, 1997.
DOI : 10.1002/(SICI)1096-9888(199711)32:10<1124::AID-JMS570>3.0.CO;2-7

I. Kuzmenkov, A. Etinger, and A. Mandelbaum, Role of hydrogen migration in the mechanism of acetic acid elimination from MH+ ions of acetates on chemical ionization and collision-induced dissociation, Journal of Mass Spectrometry, vol.27, issue.8, p.797, 1999.
DOI : 10.1002/(SICI)1096-9888(199908)34:8<797::AID-JMS834>3.0.CO;2-X