. Vilégié-en-europe, Les équipes de recherche en informatique biomédicale cherchent activement des solutions innovantes afin d'interconnecter les systèmes de santé pour encore mieux connecter les hommes et leurs connaissances Le domaine de la santé est un monde ouvert où l'information se doit de circuler entre professionnels, mais aussi entre professionnels et patients. Fluidifier les échanges électroniques permettra , nous l'espérons, de donner aux professionnels de santé l'information dont ils ont besoin

A. Einstein, Les machines un jour pourront résoudre tous les problèmes, mais jamais aucune d'entre elles ne pourra en poser un

. Bibliographie, Data Semantics. IFIP Working Conference of Data Base Management, pp.1-60, 1974.

. Antonioletti, R. Atkinson, . Baxter, and . Borley, The design and implementation of Grid database services in OGSA-DAI. Concurrency and Computation : Practice & Experience, 1983.

. Dgt-arts, G. Nf-de-keizer, and . Scheffer, Defining and Improving Data Quality in Medical Registries: A Literature Review, Case Study, and Generic Framework, Journal of the American Medical Informatics Association, vol.9, issue.6, pp.600-645, 2002.
DOI : 10.1197/jamia.M1087

Z. Baril and . Bellahsène, Designing and Managing an XML Warehouse. XML Data Management : Native XML and XML-Enabled Database Systems, pp.455-474, 2003.
URL : https://hal.archives-ouvertes.fr/lirmm-00269662

R. Victor, G. Basili, H. Caldiera, and . Dieter-rombach, Encyclopedia of Software Engineering, Experience Factory, p.45, 2002.

]. Beneventano, S. Bergamaschi, F. Guerra, and M. Vincini, The MOMIS approach to Information Integration, 2001.

. Berners-lee, Scientific publishing on the semantic web, Nature, vol.33, p.59, 2001.

[. Berti-equille and F. Moussouni, Quality-aware integration and warehousing of genomic data, Proceedings of the 10th international conference on, 1944.

R. Bizer and . Cyganiak, D2RQ-Lessons Learned, Proceedings of the W3C Workshop on, 0122.

M. Bourigault and . Slodzian, Pour une terminologie textuelle, Terminologies Nouvelles, p.108, 1999.

N. Bourigault and . Aussenac-gilles, Construction de ressources terminologiques ou ontologiques ?? partir de textes Un cadre unificateur pour trois ??tudes de cas, Revue d'intelligence artificielle, vol.18, issue.1, p.35, 2004.
DOI : 10.3166/ria.18.87-110

P. Bracchi, G. Paolini, and . Pelagatti, Binary Logical Associations in Data Modelling, IFIP Working Conference on Modelling in data Base Management Systems, pp.125-148, 1976.

. Broekstra, . Broekstra, . Kampman, and . Van-harmelen, Sesame : A generic architecture for storing and querying rdf and rdf schema. The Semantic Web?ISWC, 0122.

. Pjb-brown and . Sonksen, Evaluation of the Quality of Information Retrieval of Clinical Findings from a Computerized Patient Database Using a Semantic Terminological Model, Journal of the American Medical Informatics Association, vol.7, issue.4, pp.392-403, 2000.
DOI : 10.1136/jamia.2000.0070392

D. Choquet, M. Kalra, and . Jaulent, Specification of an Inter- Operability Platform for the integration and exploitation of distributed clinical data. American Medical Informatics Association Annual Conference, pp.1-1, 2009.

R. Choquet, D. Karlsson, D. Schober, P. Daumke, P. Ruch et al., Exchanging biomedical information at large scale using the Semantic Web, XXIII International Conference of the European Federation for Medical Informatics (MIE), p.159, 2011.

. Codd, A relational model of data for large shared data banks, Communications of the ACM, 1970.

. Codd, Extending the database relational model to capture more meaning, ACM Transactions on Database Systems, vol.4, issue.4, 1979.
DOI : 10.1145/320107.320109

M. Coloma, G. Schuemie, and . Trifiro, Combining electronic healthcare databases in Europe to allow for largescale drug safety monitoring : the EUADR Project, Pharmacoepidemiology and Drug Safety, 1998.

]. S. Davidson, C. Overton, V. Tannen, and L. Wong, BioKleisli : A Digital Library for Biomedical Researchers, p.83, 1996.

D. Roo, Euler proof mechanism, Internet, p.40, 2002.

F. De and S. , Writings in general linguistics. books.google.com, 1916.

]. Deen, R. Amin, and M. Taylor, Data Integration in Distributed Databases, IEEE Transactions on Software Engineering, vol.13, issue.7, pp.860-864, 1987.
DOI : 10.1109/TSE.1987.233497

. Deming, Out of the Crisis, 1944.

D. Valentin and P. Nadkarni, Guidelines for the effective use of entity-attribute-value modeling for biomedical databases, International Journal of Medical Informatics, vol.76, pp.11-12, 2007.

. Dittrich and . Dittrich, Object-oriented database systems (extended abstract) : the notions and the issues. OODBS : international workshop on Objectoriented database systems, pp.2-4, 1920.

. Gacia, Perspectives in Semantic Interoperability, p.181, 2011.

[. Garcia-molina, Y. Papakonstantinou, D. Quass, A. Rajaraman, Y. Sagiv et al., The TSIMMIS Approach to Mediation : Data Models and Languages, Journal of Intelligent Information Systems, vol.8, issue.2, pp.117-132, 1997.
DOI : 10.1023/A:1008683107812

F. Goasdoué and M. Rousset, The Use of CARIN Language And Algorithms For Information Integration, 1999.

A. Goldberg, . Niemierko, and . Turchin, Analysis of Data Errors in Clinical Research Databases, AMIA Annual Symposium Proceedings, pp.242-287, 2008.

. Gomez-perez, A Gomez-Perez et M Fernández-López. Ontological engineering, p.41, 2004.

A. Gorman and . Tolk, Next generation data interoperability : it's all about metadata. . . . of Fall Simulation Interoperability, p.80, 2006.

. Gruber, A translation approach to portable ontology specifications . Knowledge acquisition, p.37, 1993.

. Guarino and . Guarino, Formal ontology in information systems, p.41, 1998.

J. Hanke, G. Lehmann, P. Bork, G. Jens, and . Reich, Associative database of protein sequences, Bioinformatics, vol.15, issue.9, pp.741-748, 1926.
DOI : 10.1093/bioinformatics/15.9.741

. Hümmer, G. Bauer, and . Harde, XCube : XML for data warehouses, 6th ACM international workshop on Data warehousing and OLAP (DOLAP), pp.33-40, 1923.

R. Ikeda and . Mizoguchi, A causal time ontology for qualitative reasoning, JOINT CONFERENCE ON, p.42, 1997.

. Kerr, R. Norris, and . Stockdale, Data Quality Information and Decision Making : A Healthcare Case Study, Proc. 18th Australasian Conference on Information Systems, 1945.

K. and K. Strehlo, Why decision support fails and how to fix it, ACM SIGMOD Record, 1921.

K. and M. Ross, The data warehouse toolkit, 21 dies in health technology and informatics, pp.802-806, 2002.

]. Schulz, D. Schober, C. Daniel, and M. Jaulent, Bridging the semantics gap between terminologies, ontologies, and information models, Studies in health technology and informatics, vol.160, pp.1000-1004, 2010.

L. Cynthia and . Sears, A dynamic partnership : celebrating our gut flora, 2005.

]. Shah, Y. Huang, T. Xu, M. Yuen, J. Ling et al., Atlas -a data warehouse for integrative bioinformatics, 2005.

J. Sheth and . Larson, Federated database systems for managing distributed, heterogeneous, and autonomous databases, ACM Computing Surveys, vol.22, issue.3, 1957.
DOI : 10.1145/96602.96604

Y. Ep-shironoshita, . Jean-mary, M. Bradley, and . Kabuka, semCDI: A Query Formulation for Semantic Data Integration in caBIG, Journal of the American Medical Informatics Association, vol.15, issue.4, pp.559-84, 2008.
DOI : 10.1197/jamia.M2732

S. Barry and W. Ceusters, HL7 RIM : an incoherent standard, Studies in health technology and informatics, vol.124, pp.133-138, 2006.

. Spackman and . Spackman, Examining SNOMED from the perspective of formal ontological principles : Some preliminary analysis and observations. Whistler, p.105, 2004.

]. R. Stevens, P. G. Baker, S. Bechhofer, G. Ng, A. Jacoby et al., TAMBIS: Transparent Access to Multiple Bioinformatics Information Sources, Bioinformatics, vol.16, issue.2, pp.184-186, 2000.
DOI : 10.1093/bioinformatics/16.2.184

. Stolba, M. Stolba, . Banek, and . Tjoa, The security issue of federated data warehouses in the area of evidence-based medicine, First International Conference on Availability, Reliability and Security (ARES'06), 1983.
DOI : 10.1109/ARES.2006.132

. Stonebraker and . Moore, Object relationnal dbms, the next great ware, 1996.

. Vn-stroetmann, P. Kalra, J. Lewalle, and . Rodrigues, Semantic interoperability for better health and safer healthcare. . . . Commission (available at, p.80, 2009.

. Taylor, Patient-centred records, p.75, 2006.

. Thalhammer, Active data warehouses: complementing OLAP with analysis rules, Data & Knowledge Engineering, vol.39, issue.3, 2001.
DOI : 10.1016/S0169-023X(01)00042-8

. Töpel, . Töpel, . Kormeier, and . Klassen, BioDWH : A data warehouse kit for life science data integration, Journal of Integrative, 1982.

. Uschold, Towards a methodology for building ontologies. Workshop on basic ontological issues in knowledge, p.38, 1995.

V. Heijst and . Schreiber, Using explicit ontologies in KBS development, International Journal of Human-Computer Studies, vol.46, issue.2-3, p.41, 1997.
DOI : 10.1006/ijhc.1996.0090

M. Vicente, J. Hodgson, O. Massidda, T. Tonjum, B. Henriques-normark et al., The fallacies of hope : will we discover new antibiotics to combat pathogenic bacteria in time ? FEMS microbiology reviews, pp.841-852, 2006.

Y. Richard and . Wang, Anchoring data quality dimensions in ontological foundations, Commun. ACM, vol.39, pp.86-95, 1996.

. Wang, A product perspective on total data quality management, Communications of the ACM, vol.41, issue.2, p.108, 1943.
DOI : 10.1145/269012.269022

. Weikum, Towards guaranteed quality and dependability of information systems, Proc. of the Conf. Datenbanksysteme inB*uro, Technik und Wissenschaft, p.44, 1999.

. Williams, The associative model of data, Journal of Database Marketing & Customer Strategy Management, vol.8, issue.4, 1925.
DOI : 10.1057/palgrave.jdm.3240049

. Wisniewski, . Kieszkowski, . Zagorski, . Trick, R. Sommers et al., Development of a Clinical Data Warehouse for Hospital Infection Control, Journal of the American Medical Informatics Association, vol.10, issue.5, pp.454-462, 2003.
DOI : 10.1197/jamia.M1299

. Zweigenbaum, Encoder l'information médicale : des terminologies aux systèmes de représentation des connaissances. Innovation Stratégique en, p.35, 1999.

R. Choquet, C. Daniel, O. Boussaid, and M. Jaulent, Etude méthodologique comparative de solutions d'entreposage de données de santé à des fins décisionnelles. 9ème Conférence internationale sur la science des systèmes de santé, 2008.

C. Lovis, Integration of biomedical data using federated databases. Proceedings of the 22th conference of swiss medical informatics, 2009.

R. Choquet, D. Kalra, and M. Jaulent, Specification of an Inter-Operability Platform for the integration and exploitation of distributed clinical data. American Medical Informatics Association Annual Conference, 2009.

D. Schober, M. Boeker, J. Bullenkamp, C. Huszka, K. Depraetere et al., The DebugIT core ontology : semantic integration of antibiotics resistance patterns.. Studies in health technology and informatics, pp.1060-1064, 2010.

D. Ouagne, N. Nadah, D. Schober, R. Choquet, D. Teodoro et al., Ensuring HL7-based information model requirements within an ontology framework.. Studies in health technology and informatics, pp.912-918, 2010.

R. Choquet, S. Qouiyd, E. Pasche, C. Daniel, O. Boussaïd et al., Un modèle de connaissances pour mesurer la qualité d'une source d'information, 2010.

A. Assele, G. Mels, R. Choquet, and M. Jaulent, Utilisation d'une ontologie comme source de données pour répondre à des questions cliniques, 2010.

C. Daniel, R. Choquet, A. Assele, F. Enders, P. Daumke et al., Comparing the DebugIT dashboards to national surveillance systems Poster, International Conference on Prevention and Infection Control, 2011.

D. Teodoro, R. Choquet, D. Schober, G. Mels, E. Pasche et al., Interoperability driven integration of biomedical data sources, XXIII International Conference of the European Federation for Medical Informatics (MIE), 2011.

R. Choquet, C. Daniel, P. Grohs, N. Douali, and M. Jaulent, Monitoring the emergence of antibiotic resistance using the technology ot the DebugIT platform in the HEGP context, BMC Proceedings, vol.5, issue.Suppl 6, 2011.
DOI : 10.1186/1753-6561-5-S6-P320
URL : https://hal.archives-ouvertes.fr/inserm-00604641