Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors, The Journal of Experimental Medicine, vol.1, issue.8, pp.1867-1873, 2006. ,
DOI : 10.1038/nri1778
All Hematopoietic Cells Develop from Hematopoietic Stem Cells through Flk2/Flt3-Positive Progenitor Cells, Cell Stem Cell, vol.9, issue.1, pp.64-73, 2011. ,
DOI : 10.1016/j.stem.2011.04.021
Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells, Proceedings of the National Academy of Sciences, vol.98, issue.25, pp.14541-14546, 2001. ,
DOI : 10.1073/pnas.261562798
Heterogeneity of Flt3-Expressing Multipotent Progenitors in Mouse Bone Marrow, The Journal of Immunology, vol.175, issue.8, pp.5016-5023, 2005. ,
DOI : 10.4049/jimmunol.175.8.5016
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow, Cell, vol.91, issue.5, pp.661-672, 1997. ,
DOI : 10.1016/S0092-8674(00)80453-5
Identification of a bone marrow precursor of the earliest thymocytes in adult mouse, Proceedings of the National Academy of Sciences, vol.104, issue.15, pp.6311-6316, 2007. ,
DOI : 10.1073/pnas.0609608104
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages, Blood, vol.111, issue.12, pp.5562-5570, 2008. ,
DOI : 10.1182/blood-2007-11-126219
Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands, The Journal of Experimental Medicine, vol.158, issue.8, pp.1977-1984, 2006. ,
DOI : 10.1073/pnas.96.17.9797
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis, Blood, vol.113, issue.4, pp.807-815, 2009. ,
DOI : 10.1182/blood-2008-08-173682
Thymopoiesis independent of common lymphoid progenitors, Nature Immunology, vol.4, issue.2, pp.168-174, 2003. ,
DOI : 10.1038/ni878
Generation of intestinal T cells from progenitors residing in gut cryptopatches Characterization of T cell differentiation in the murine gut Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus, Science. J Exp Med. J Immunol, vol.280195175, issue.147, pp.275-278437, 1998. ,
Major T Cell Progenitor Activity in Bone Marrow???derived Spleen Colonies, The Journal of Experimental Medicine, vol.189, issue.7, pp.919-929, 2002. ,
DOI : 10.1084/jem.20011475
Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse Identification of an IL-7-dependent pre-T committed population in the spleen, J Immunol. J Immunol, vol.174179, issue.175, pp.1980-19882925, 2005. ,
Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation, Blood, vol.107, issue.9, pp.3511-3519, 2006. ,
DOI : 10.1182/blood-2005-08-3454
Gene coexpression analysis in single cells indicates lymphomyeloid copriming in short-term hematopoietic stem cells and multipotent progenitors Quantification of multiple gene expression in individual cells CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus, J Immunol. Genome Res. Blood, vol.18414115, issue.21, pp.4907-49171938, 2004. ,
Complex regulation of CCR9 at multiple discrete stages of T???cell development, European Journal of Immunology, vol.274, issue.1, pp.73-81, 2006. ,
DOI : 10.1002/eji.200535203
Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages, Blood. Immunol Today, vol.8920, issue.254, pp.3636-3643184, 1997. ,
E2A proteins promote development of lymphoid-primed multipotent progenitors Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)-mice Two waves of recombinase gene expression in developing thymocytes, Immunity. J Exp Med. J Exp Med, vol.29194179, issue.284, pp.217-2271141, 1994. ,
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination, Immunity, vol.11, issue.3, pp.299-308, 1999. ,
DOI : 10.1016/S1074-7613(00)80105-3
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1, Immunity, vol.10, issue.5, pp.547-558, 1999. ,
DOI : 10.1016/S1074-7613(00)80054-0
GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry Bhandoola A. The earliest thymic progenitors for T cells possess myeloid lineage potential, Blood. Bell JJ Nature, vol.119452, issue.327188, pp.2242-2251764, 2008. ,
Adult T-cell progenitors retain myeloid potential, Nature, vol.194, issue.7188, pp.768-772, 2008. ,
DOI : 10.1038/nature06839
In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors, Blood, vol.117, issue.9, pp.2618-2624, 2011. ,
DOI : 10.1182/blood-2010-05-287102
Transcription from the RAG1 Locus Marks the Earliest Lymphocyte Progenitors in Bone Marrow, Immunity, vol.17, issue.2, pp.117-130, 2002. ,
DOI : 10.1016/S1074-7613(02)00366-7
Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus, The Journal of Immunology, vol.185, issue.1, pp.284-293, 2010. ,
DOI : 10.4049/jimmunol.1000679
Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation, Blood, vol.93, issue.8, pp.2431-2448, 1999. ,
Upregulation of Flt3 Expression within the Bone Marrow Lin???Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity, Immunity, vol.15, issue.4, pp.659-669, 2001. ,
DOI : 10.1016/S1074-7613(01)00220-5
Circulating hematopoietic progenitors with T lineage potential, Nature Immunology, vol.90, issue.9, pp.953-960, 2004. ,
DOI : 10.1038/23287
Live imaging of emerging hematopoietic stem cells and early thymus colonization, Blood, vol.111, issue.3, pp.1147-56, 2008. ,
DOI : 10.1182/blood-2007-07-099499
Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus, Nature Reviews Immunology, vol.3, issue.11, pp.859-66, 2003. ,
DOI : 10.1038/nri1223
Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25, The Journal of Experimental Medicine, vol.96, issue.4, pp.761-78, 2009. ,
DOI : 10.1161/01.ATV.0000237569.95046.b9
Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1, Nature Immunology, vol.84, issue.6, pp.626-660, 2005. ,
DOI : 10.1093/nar/30.9.e36
The Importation of Hematogenous Precursors by the Thymus Is a Gated Phenomenon in Normal Adult Mice, The Journal of Experimental Medicine, vol.232, issue.3, pp.365-74, 2001. ,
DOI : 10.1084/jem.126.4.715
Journey through the thymus: stromal guides for T-cell development and selection, Nature Reviews Immunology, vol.168, issue.2, pp.127-162, 2006. ,
DOI : 10.1038/nri1781
Acute graft-versus-host disease transiently impairs thymic output in young patients after allogeneic hematopoietic stem cell transplantation, Blood, vol.113, issue.25, pp.6477-84, 2009. ,
DOI : 10.1182/blood-2008-09-176594
The generation and fate of thymocytes, Semin Immunol, vol.2, pp.3-12, 1990. ,
Control points in early T-cell development, Immunology Today, vol.14, issue.11, pp.547-53, 1993. ,
DOI : 10.1016/0167-5699(93)90186-O
Thymopoiesis independent of common lymphoid progenitors, Nature Immunology, vol.4, issue.2, pp.168-74, 2003. ,
DOI : 10.1038/ni878
Zoned Out: Functional Mapping of Stromal Signaling Microenvironments in the Thymus, Annual Review of Immunology, vol.25, issue.1, pp.649-79, 2007. ,
DOI : 10.1146/annurev.immunol.23.021704.115715
DEVELOPMENT OF HUMAN LYMPHOID CELLS, Annual Review of Immunology, vol.24, issue.1, pp.287-320, 2006. ,
DOI : 10.1146/annurev.immunol.24.021605.090612
The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential, Blood, vol.105, issue.5, pp.1930-1936, 2005. ,
DOI : 10.1182/blood-2004-08-3087
A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision, The Journal of Experimental Medicine, vol.126, issue.1, pp.21-31, 2005. ,
DOI : 10.1016/S1074-7613(00)80268-X
The earliest thymic progenitors for T cells possess myeloid lineage potential, Nature, vol.20, issue.7188, pp.764-771, 2008. ,
DOI : 10.1038/nature06840
Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny, Journal of Experimental Medicine, vol.184, issue.3, pp.903-914, 1996. ,
DOI : 10.1084/jem.184.3.903
Kinetics of T cell receptor ??, ??, and ?? rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44+CD25+ Pro-T thymocytes, Proceedings of the National Academy of Sciences, vol.95, issue.21, pp.12522-12529, 1998. ,
DOI : 10.1073/pnas.95.21.12522
Characterization of TCR gene rearrangements during adult murine T cell development, J Immunol, vol.162, pp.2575-80, 1999. ,
Developmental and Molecular Characterization of Emerging ??- and ????-Selected Pre-T Cells in the Adult Mouse Thymus, Immunity, vol.24, issue.1, pp.53-64, 2006. ,
DOI : 10.1016/j.immuni.2005.11.012
Reprogramming of Committed T Cell Progenitors to Macrophages and Dendritic Cells by C/EBP?? and PU.1 Transcription Factors, Immunity, vol.25, issue.5, pp.731-775, 2006. ,
DOI : 10.1016/j.immuni.2006.09.011
Notch/Delta signaling constrains reengineering of pro-T cells by PU.1, Proceedings of the National Academy of Sciences, vol.103, issue.32, pp.11993-12001, 2006. ,
DOI : 10.1073/pnas.0601188103
Differentiation of cloned populations of immature B cells after transformation with abelson murine leukemia virus, Cell, vol.32, issue.3, pp.903-914, 1983. ,
DOI : 10.1016/0092-8674(83)90075-2
In vitromodels of T cell development, Seminars in Immunology, vol.11, issue.1, pp.3-12, 1999. ,
DOI : 10.1006/smim.1998.0151
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination, Immunity, vol.11, issue.3, pp.299-308, 1999. ,
DOI : 10.1016/S1074-7613(00)80105-3
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1, Immunity, vol.10, issue.5, pp.547-58, 1999. ,
DOI : 10.1016/S1074-7613(00)80054-0
Involvement of the c-kit receptor in the adhesion of hematopoietic stem cells to stromal cells, Exp Hematol, vol.22, pp.979-84, 1994. ,
Generation of Lytic Natural Killer 1.1+, Ly-49- Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Developmental Intermediates, Journal of Experimental Medicine, vol.158, issue.1, pp.1609-1623, 1997. ,
DOI : 10.1016/S0065-2776(08)60664-1
Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro, Immunity, vol.17, issue.6, pp.749-56, 2002. ,
DOI : 10.1016/S1074-7613(02)00474-0
Hierarchy of Notch???Delta interactions promoting T cell lineage commitment and maturation, The Journal of Experimental Medicine, vol.5, issue.2, pp.331-374, 2007. ,
DOI : 10.1006/meth.2000.1022
Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes, The Journal of Immunology, vol.185, issue.2, pp.867-76, 2010. ,
DOI : 10.4049/jimmunol.1000782
Human bone marrow CD34+ progenitor cells mature to T cells on OP9-DL1 stromal cell line without thymus microenvironment, Blood Cells, Molecules, and Diseases, vol.33, issue.3, pp.227-259, 2004. ,
DOI : 10.1016/j.bcmd.2004.08.007
Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro, Blood, vol.105, issue.4, pp.1431-1440, 2005. ,
DOI : 10.1182/blood-2004-04-1293
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development, Nature Immunology, vol.161, issue.3, pp.235-276, 2001. ,
DOI : 10.1038/85294
Regulation of ????/???? T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling, Immunity, vol.20, issue.5, pp.611-633, 2004. ,
DOI : 10.1016/S1074-7613(04)00109-8
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment, The Journal of Experimental Medicine, vol.105, issue.11, pp.2515-2538, 2008. ,
DOI : 10.1038/71540
Delta-like 4 is indispensable in thymic environment specific for T cell development, The Journal of Experimental Medicine, vol.18, issue.11, pp.2507-2520, 2008. ,
DOI : 10.1006/scdb.1998.0266
Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation, Nature Medicine, vol.103, issue.9, pp.1039-1086, 2006. ,
DOI : 10.1038/nm1463
Gene therapy progress and prospects: Novel gene therapy approaches for AIDS, Gene Therapy, vol.12, issue.6, pp.467-76, 2005. ,
DOI : 10.1038/sj.gt.3302488
Reconstitution of anti-HIV effector functions of primary human CD8 T?lymphocytes by transfer of HIV-specific ???TCR genes, European Journal of Immunology, vol.33, issue.12, pp.3379-88, 2004. ,
DOI : 10.1002/eji.200425568
Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling Strategies to enhance T-cell reconstitution in immunocompromised patients, Cancer Research Nature Reviews, vol.67, issue.4, pp.2425-2434, 2004. ,
Pax5: the guardian of B cell identity and function, Nature Immunology, vol.306, issue.5, pp.463-70, 2007. ,
DOI : 10.1038/ni1454
Gene Coexpression Analysis in Single Cells Indicates Lymphomyeloid Copriming in Short-Term Hematopoietic Stem Cells and Multipotent Progenitors, The Journal of Immunology, vol.184, issue.9, pp.4907-4924, 2010. ,
DOI : 10.4049/jimmunol.0902184
The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal, Science, vol.327, issue.5967, pp.879-83, 2010. ,
DOI : 10.1126/science.1182378
Notch Signaling: Cell Fate Control and Signal Integration in Development, Science, vol.284, issue.5415, pp.770-776, 1999. ,
DOI : 10.1126/science.284.5415.770
Surface Expression of Notch1 on Thymocytes: Correlation with the Double-Negative to Double-Positive Transition, The Journal of Immunology, vol.171, issue.5, pp.2296-304, 2003. ,
DOI : 10.4049/jimmunol.171.5.2296
Characterization of the transcriptional expression of Notch-1 signaling pathway members, Deltex and HES-1, in developing mouse thymocytes, Developmental & Comparative Immunology, vol.26, issue.6, pp.575-88, 2002. ,
DOI : 10.1016/S0145-305X(01)00095-7
Inactivation of Notch1 Impairs VDJ?? Rearrangement and Allows pre-TCR-Independent Survival of Early ???? Lineage Thymocytes, Immunity, vol.16, issue.6, pp.869-79, 2002. ,
DOI : 10.1016/S1074-7613(02)00330-8
Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation, The Journal of Immunology, vol.172, issue.9, pp.5230-5239, 2004. ,
DOI : 10.4049/jimmunol.172.9.5230
Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor???Ligand Interactions, The Journal of Experimental Medicine, vol.13, issue.4, pp.469-79, 2004. ,
DOI : 10.1084/jem.194.2.127
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A, Genes & Development, vol.23, issue.14, pp.1665-76, 2009. ,
DOI : 10.1101/gad.1793709
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment, The Journal of Experimental Medicine, vol.113, issue.5, pp.1329-1371, 2006. ,
DOI : 10.1038/ni923
p53 regulates thymic Notch1 activation, European Journal of Immunology, vol.34, issue.3, pp.726-760, 2004. ,
DOI : 10.1002/eji.200324772
Role for Hes1-Induced Phosphorylation in Groucho-Mediated Transcriptional Repression, Molecular and Cellular Biology, vol.22, issue.2, pp.389-99, 2002. ,
DOI : 10.1128/MCB.22.2.389-399.2002
The bHLH gene Hes1 is essential for expansion of early T cell precursors, Genes & Development, vol.13, issue.9, pp.1203-1213, 1999. ,
DOI : 10.1101/gad.13.9.1203
Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations, Oncogene, vol.21, issue.24, pp.3855-63, 2002. ,
DOI : 10.1038/sj.onc.1205487
Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes, PLoS ONE, vol.317, issue.8, p.6678, 2009. ,
DOI : 10.1371/journal.pone.0006678.t001
Homozygous deletions and point mutations of the Rit1/Bcl11b gene in ??-ray induced mouse thymic lymphomas, Biochemical and Biophysical Research Communications, vol.301, issue.2, pp.598-603, 2003. ,
DOI : 10.1016/S0006-291X(02)03069-3
Involvement of V(D)J recombinase in the generation of intragenic deletions in the Rit1/Bcl11b tumor suppressor gene in ??-ray-induced thymic lymphomas and in normal thymus of the mouse, Carcinogenesis, vol.25, issue.6, pp.1069-75, 2004. ,
DOI : 10.1093/carcin/bgh094
The cardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35. 1;q32. 2), Cancer Research, vol.63, pp.5329-5363, 2003. ,
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL, Leukemia, vol.19, issue.2, pp.201-209, 2005. ,
DOI : 10.1038/sj.leu.2403619
BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter, Oncogene, vol.983, issue.45, pp.6753-64, 2005. ,
DOI : 10.1101/GAD.13.18.2388
Evolution of Genetic Networks Underlying the Emergence of Thymopoiesis in Vertebrates, Journal of End-to-End-testing, vol.138, issue.1, pp.186-97, 2009. ,
DOI : 10.1016/S9999-9994(09)20360-6
Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion, Science, vol.329, issue.5987, pp.85-94, 2010. ,
DOI : 10.1126/science.1188063
An Essential Developmental Checkpoint for Production of the T Cell Lineage, Science, vol.329, issue.5987, pp.93-99, 2010. ,
DOI : 10.1126/science.1188995
WNT signalling and haematopoiesis: a WNT???WNT situation, Nature Reviews Immunology, vol.169, issue.1, pp.21-30, 2005. ,
DOI : 10.1101/gad.1249504
Critical involvement of Tcf-1 in expansion of thymocytes, J Immunol, vol.161, pp.3984-91, 1998. ,
Wnt signalling: variety at the core, Journal of Cell Science, vol.120, issue.3, pp.385-93, 2007. ,
DOI : 10.1242/jcs.03363
Diversity of LEF/TCF action in development and disease, Oncogene, vol.176, issue.57, pp.7492-504, 2006. ,
DOI : 10.1128/MCB.20.12.4238-4252.2000
Wnt Target Genes Identified by DNA Microarrays in Immature CD34+ Thymocytes Regulate Proliferation and Cell Adhesion, The Journal of Immunology, vol.172, issue.2, pp.1099-108, 2004. ,
DOI : 10.4049/jimmunol.172.2.1099
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1, Nature Genetics, vol.93, issue.1, pp.27-37, 2006. ,
DOI : 10.1038/ng1679
Early hematopoietic lineage restrictions directed by Ikaros, Nature Immunology, vol.99, issue.4, pp.382-91, 2006. ,
DOI : 10.1038/ni1314
The ikaros gene is required for the development of all lymphoid lineages, Cell, vol.79, issue.1, pp.143-56, 1994. ,
DOI : 10.1016/0092-8674(94)90407-3
Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development, Molecular and Cellular Biology, vol.28, issue.24, pp.7465-75, 2008. ,
DOI : 10.1128/MCB.00715-08
URL : https://hal.archives-ouvertes.fr/inserm-00350904
The zinc finger transcription factor Growth factor independence 1 (Gfi1), The International Journal of Biochemistry & Cell Biology, vol.37, issue.3, pp.541-547, 2005. ,
DOI : 10.1016/j.biocel.2004.08.011
The Transcriptional Repressor Gfi1 Controls STAT3-Dependent Dendritic Cell Development and Function, Immunity, vol.22, issue.6, pp.717-745, 2005. ,
DOI : 10.1016/j.immuni.2005.04.007
Intrinsic Requirement for Zinc Finger Transcription Factor Gfi-1 in Neutrophil Differentiation, Immunity, vol.18, issue.1, pp.109-129, 2003. ,
DOI : 10.1016/S1074-7613(02)00501-0
T Cell Progenitors and CD4/CD8 Lineage Decision in the Thymus, The Journal of Experimental Medicine, vol.18, issue.7, pp.831-875, 2003. ,
DOI : 10.1084/jem.190.11.1605
Growth Factor Independence-1B Expression Leads to Defects in T Cell Activation, IL-7 Receptor ?? Expression, and T Cell Lineage Commitment, The Journal of Immunology, vol.170, issue.5, pp.2356-66, 2003. ,
DOI : 10.4049/jimmunol.170.5.2356
The Transcriptional Repressor GFI-1 Antagonizes PU.1 Activity through Protein-Protein Interaction, Journal of Biological Chemistry, vol.282, issue.9, pp.6473-83, 2007. ,
DOI : 10.1074/jbc.M607613200
Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1, Science, vol.288, issue.5470, pp.1439-1480, 2000. ,
DOI : 10.1126/science.288.5470.1439
PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors, Immunity, vol.16, issue.2, pp.297-309, 2002. ,
DOI : 10.1016/S1074-7613(02)00269-8
T cell development in PU. 1-deficient mice, J Immunol, vol.163, pp.2681-2688, 1999. ,
Targeted disruption of the PU. 1 gene results in multiple hematopoietic abnormalities, The EMBO Journal, vol.15, pp.5647-58, 1996. ,
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages, Science, vol.265, issue.5178, pp.1573-1580, 1994. ,
DOI : 10.1126/science.8079170
Notch signaling controls the generation and differentiation of early T lineage progenitors, Nature Immunology, vol.165, issue.7, pp.663-70, 2005. ,
DOI : 10.1084/jem.163.1.1
Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection ,
Subversion of T lineage commitment by PU.1 in a clonal cell line system, Developmental Biology, vol.280, issue.2, pp.448-66, 2005. ,
DOI : 10.1016/j.ydbio.2005.01.027
Inhibition of EBF function by active Notch signaling reveals a novel regulatory pathway in early B-cell development, Blood, vol.106, issue.6, pp.1995-2001, 2005. ,
DOI : 10.1182/blood-2004-12-4744
Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow, Proceedings of the National Academy of Sciences, vol.96, issue.25, pp.14493-14501, 1999. ,
DOI : 10.1073/pnas.96.25.14493
Stepwise Development of Committed Progenitors in the Bone Marrow That Generate Functional T Cells in the Absence of the Thymus, The Journal of Immunology, vol.175, issue.7 ,
DOI : 10.4049/jimmunol.175.7.4363
Major T Cell Progenitor Activity in Bone Marrow???derived Spleen Colonies, The Journal of Experimental Medicine, vol.189, issue.7, pp.919-948, 2002. ,
DOI : 10.1084/jem.20011475
Extrathymic Hemopoietic Progenitors Committed to T Cell Differentiation in the Adult Mouse, The Journal of Immunology, vol.174, issue.4 ,
DOI : 10.4049/jimmunol.174.4.1980
Identification of an IL-7-Dependent Pre-T Committed Population in the Spleen, The Journal of Immunology, vol.179, issue.5, pp.2925-2960, 2007. ,
DOI : 10.4049/jimmunol.179.5.2925
Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization, The EMBO Journal, vol.13, pp.4229-4269, 1994. ,
Identification of a T Lineage-Committed Progenitor in Adult Blood, Immunity, vol.26, issue.1, pp.105-121, 2007. ,
DOI : 10.1016/j.immuni.2006.12.004
Regulation of Extrathymic T Cell Development and Turnover by Oncostatin M, The Journal of Immunology, vol.164, issue.11, pp.5713-5733, 2000. ,
DOI : 10.4049/jimmunol.164.11.5713
Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches, Science, vol.280, issue.5361, pp.275-283, 1998. ,
DOI : 10.1126/science.280.5361.275
The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs, Nature Immunology, vol.195, issue.1, pp.76-82, 2006. ,
DOI : 10.1038/ni1293
Role of the gut as a primary lymphoid organ, Immunology Letters, vol.140, issue.1-2 ,
DOI : 10.1016/j.imlet.2011.05.009
Thymic microvascular system, Microscopy Research and Technique, vol.206, issue.3, pp.287-99, 1997. ,
DOI : 10.1002/(SICI)1097-0029(19970801)38:3<287::AID-JEMT9>3.0.CO;2-J
Jumping to rafts: gatekeeper role of bilayer elasticity, Trends in Biochemical Sciences, vol.29, issue.6, pp.325-355, 2004. ,
DOI : 10.1016/j.tibs.2004.04.002
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1, Nature, vol.427, issue.6972, pp.355-60, 2004. ,
DOI : 10.1038/nature02284
Sphingosine-1-phosphate receptors and the development of the vascular system, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1582, issue.1-3, pp.222-229, 2002. ,
DOI : 10.1016/S1388-1981(02)00175-0
Neural Crest-Derived Pericytes Promote Egress of Mature Thymocytes at the Corticomedullary Junction, Science, vol.328, issue.5982, pp.1129-1164, 2010. ,
DOI : 10.1126/science.1188222
Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients, Science, vol.309, issue.5741, pp.1735-1744, 2005. ,
DOI : 10.1126/science.1113640
Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies, The Journal of Immunology, vol.183, issue.11, pp.7212-7234, 2009. ,
DOI : 10.4049/jimmunol.0902432
URL : https://hal.archives-ouvertes.fr/hal-00433541
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision, International Immunology, vol.14, issue.6, pp.637-682, 2002. ,
DOI : 10.1093/intimm/dxf030
Helix-loop-helix proteins and lymphocyte development, Nature Immunology, vol.220, issue.11, pp.1079-86, 2005. ,
DOI : 10.1038/nrc1673
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines., Molecular and Cellular Biology, vol.13, issue.9, pp.5620-5628, 1993. ,
DOI : 10.1128/MCB.13.9.5620
The pT?? promoter and enhancer are direct targets for transactivation by E box-binding proteins, European Journal of Immunology, vol.32, issue.3, pp.911-931, 2002. ,
DOI : 10.1002/1521-4141(200203)32:3<911::AID-IMMU911>3.0.CO;2-H
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype, Blood, vol.106, issue.2, pp.494-504, 2005. ,
DOI : 10.1182/blood-2004-08-3280
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells, The Journal of Experimental Medicine, vol.2, issue.8, pp.1945-57, 2007. ,
DOI : 10.1016/j.immuni.2005.03.011
Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors., Molecular and Cellular Biology, vol.14, issue.1, pp.473-83, 1994. ,
DOI : 10.1128/MCB.14.1.473
Ikaros DNA-Binding Proteins Direct Formation of Chromatin Remodeling Complexes in Lymphocytes, Immunity, vol.10, issue.3, pp.345-55, 1999. ,
DOI : 10.1016/S1074-7613(00)80034-5
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis, Proceedings of the National Academy of Sciences, vol.100, issue.13, pp.7731-7737, 2003. ,
DOI : 10.1073/pnas.1232420100
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development, Cell, vol.111, issue.5, pp.621-654, 2002. ,
DOI : 10.1016/S0092-8674(02)01111-X
A cis element in the recombination activating gene locus regulates gene expression by counteracting a distant silencer, Nature Immunology, vol.5, issue.4, pp.443-50, 2004. ,
DOI : 10.1038/ni1053
Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival, Blood, vol.106, issue.5, pp.1726-1759, 2005. ,
DOI : 10.1182/blood-2005-01-0337
Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates, Cell, vol.126, issue.4, pp.755-66, 2006. ,
DOI : 10.1016/j.cell.2006.06.052
Roles of EBF and Pax-5 in B lineage commitment and development, Seminars in Immunology, vol.14, issue.6, pp.415-437, 2002. ,
DOI : 10.1016/S1044532302000763
The CD8?? Gene Locus Is Regulated by the Ikaros Family of Proteins, Molecular Cell, vol.10, issue.6, pp.1403-1418, 2002. ,
DOI : 10.1016/S1097-2765(02)00711-6
Upregulation of Flt3 Expression within the Bone Marrow Lin???Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity, Immunity, vol.15, issue.4, pp.659-669, 2001. ,
DOI : 10.1016/S1074-7613(01)00220-5
Identification of Flt3+ Lympho-Myeloid Stem Cells Lacking Erythro-Megakaryocytic Potential, Cell, vol.121, issue.2, pp.295-306, 2005. ,
DOI : 10.1016/j.cell.2005.02.013
An attempt to produce ???pre-T??? cell hybridomas and to identify their antigens, European Journal of Immunology, vol.156, issue.11, pp.1391-1399, 1986. ,
DOI : 10.1002/eji.1830161113
Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor???Deficient Mice, Cell, vol.89, issue.7, pp.1033-1041, 1997. ,
DOI : 10.1016/S0092-8674(00)80291-3
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages, Nature, vol.362, issue.6774, pp.193-197, 2000. ,
DOI : 10.1038/35004599
Thymopoiesis independent of common lymphoid progenitors, Nature Immunology, vol.4, issue.2, pp.168-174, 2003. ,
DOI : 10.1038/ni878
Definition of Regulatory Network Elements for T Cell Development by Perturbation Analysis with PU.1 and GATA-3, Developmental Biology, vol.246, issue.1, pp.103-121, 2002. ,
DOI : 10.1006/dbio.2002.0674
Extrathymic Hemopoietic Progenitors Committed to T Cell Differentiation in the Adult Mouse, The Journal of Immunology, vol.174, issue.4, 1980. ,
DOI : 10.4049/jimmunol.174.4.1980
Hierarchy of Notch???Delta interactions promoting T cell lineage commitment and maturation, The Journal of Experimental Medicine, vol.5, issue.2, pp.331-343, 2007. ,
DOI : 10.1006/meth.2000.1022
Notch signalling: a simple pathway becomes complex, Nature Reviews Molecular Cell Biology, vol.281, issue.9, pp.678-689, 2006. ,
DOI : 10.1016/S1534-5807(04)00097-8
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells, Cell Stem Cell, vol.6, issue.3, pp.251-264, 2010. ,
DOI : 10.1016/j.stem.2010.02.001
GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells, Blood, vol.118, issue.5, pp.1291-1293, 2011. ,
DOI : 10.1182/blood-2011-02-338046
Osteoblastic cells regulate the haematopoietic stem cell niche, Nature, vol.425, issue.6960, pp.841-846, 2003. ,
DOI : 10.1038/nature02040
Early Defect Prethymic in Bone Marrow T Cell Progenitors in Athymic nu/nu Mice, The Journal of Immunology, vol.171, issue.3, pp.1207-1215, 2003. ,
DOI : 10.4049/jimmunol.171.3.1207
Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells, Proceedings of the National Academy of Sciences, vol.98, issue.25, pp.14541-14546, 2001. ,
DOI : 10.1073/pnas.261562798
Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway, Proceedings of the National Academy of Sciences, vol.98, issue.13, pp.7455-7460, 2001. ,
DOI : 10.1073/pnas.131559798
Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow, Proceedings of the National Academy of Sciences, vol.96, issue.25, pp.14493-14498, 1999. ,
DOI : 10.1073/pnas.96.25.14493
PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors, Immunity, vol.16, issue.2, pp.297-309, 2002. ,
DOI : 10.1016/S1074-7613(02)00269-8
Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1, Science, vol.288, issue.5470, pp.1439-1441, 2000. ,
DOI : 10.1126/science.288.5470.1439
E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors, Immunity, vol.29, issue.2, pp.217-227, 2008. ,
DOI : 10.1016/j.immuni.2008.05.015
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance, Nature Immunology, vol.126, issue.3, pp.314-322, 2005. ,
DOI : 10.1111/j.1600-0609.2004.00268.x
The location and cellular composition of the hemopoietic stem cell niche, Cytotherapy, vol.14, issue.2, pp.135-143, 2012. ,
DOI : 10.3109/14653249.2011.630729
THE FUNCTION OF E- AND ID PROTEINS IN LYMPHOCYTE DEVELOPMENT, Nature Reviews Immunology, vol.94, issue.3, pp.193-199, 2001. ,
DOI : 10.1084/jem.192.12.1775
Stepwise Development of Committed Progenitors in the Bone Marrow That Generate Functional T Cells in the Absence of the Thymus, The Journal of Immunology, vol.175, issue.7, pp.4363-4373, 2005. ,
DOI : 10.4049/jimmunol.175.7.4363
Identification of an IL-7-Dependent Pre-T Committed Population in the Spleen, The Journal of Immunology, vol.179, issue.5, pp.2925-2935, 2007. ,
DOI : 10.4049/jimmunol.179.5.2925
Gene Coexpression Analysis in Single Cells Indicates Lymphomyeloid Copriming in Short-Term Hematopoietic Stem Cells and Multipotent Progenitors, The Journal of Immunology, vol.184, issue.9, pp.4907-4917, 2010. ,
DOI : 10.4049/jimmunol.0902184
A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4- CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression, J Immunol, vol.150, pp.4244-4252, 1993. ,
Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25, The Journal of Experimental Medicine, vol.96, issue.4, pp.761-778, 2009. ,
DOI : 10.1161/01.ATV.0000237569.95046.b9
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow, Journal of Experimental Medicine, vol.173, issue.5, pp.1213-1225, 1991. ,
DOI : 10.1084/jem.173.5.1213
GATA-3 is required for early T lineage progenitor development, The Journal of Experimental Medicine, vol.19, issue.13, pp.2987-3000, 2009. ,
DOI : 10.1038/ni1128
Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment, Blood, vol.110, issue.5, pp.1420-1428, 2007. ,
DOI : 10.1182/blood-2007-02-071761
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment, The Journal of Experimental Medicine, vol.113, issue.5, pp.1329-1342, 2006. ,
DOI : 10.1038/ni923
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation., Proceedings of the National Academy of Sciences, vol.89, issue.4, pp.1502-1506, 1992. ,
DOI : 10.1073/pnas.89.4.1502
Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop, Journal of Experimental Medicine, vol.184, issue.4, pp.1449-1459, 1996. ,
DOI : 10.1084/jem.184.4.1449
SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells, Cell, vol.121, issue.7, pp.1109-1121, 2005. ,
DOI : 10.1016/j.cell.2005.05.026
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines, Nature, vol.407, issue.6802, pp.383-386, 2000. ,
DOI : 10.1038/35030112
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow, Cell, vol.91, issue.5, pp.661-672, 1997. ,
DOI : 10.1016/S0092-8674(00)80453-5
Identification of a T Lineage-Committed Progenitor in Adult Blood, Immunity, vol.26, issue.1, pp.105-116, 2007. ,
DOI : 10.1016/j.immuni.2006.12.004
CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus, Blood, vol.115, issue.10, pp.1906-1912, 2010. ,
DOI : 10.1182/blood-2009-07-235721
GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry, Blood, vol.119, issue.10, pp.2242-2251, 2012. ,
DOI : 10.1182/blood-2011-07-366070
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311255
Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors, The Journal of Experimental Medicine, vol.1, issue.8, pp.1867-1873, 2006. ,
DOI : 10.1038/nri1778
T and B lymphocyte differentiation from hematopoietic stem cell, Seminars in Immunology, vol.20, issue.4, pp.207-212, 2008. ,
DOI : 10.1016/j.smim.2008.05.002
Heterogeneity of Flt3-Expressing Multipotent Progenitors in Mouse Bone Marrow, The Journal of Immunology, vol.175, issue.8, pp.5016-5023, 2005. ,
DOI : 10.4049/jimmunol.175.8.5016
Pertussis toxin-sensitive G proteins regulate lymphoid lineage specification in multipotent hematopoietic progenitors, Blood, vol.113, issue.23, pp.5757-5764, 2009. ,
DOI : 10.1182/blood-2009-01-201939
Reprogramming of Committed T Cell Progenitors to Macrophages and Dendritic Cells by C/EBP?? and PU.1 Transcription Factors, Immunity, vol.25, issue.5, pp.731-744, 2006. ,
DOI : 10.1016/j.immuni.2006.09.011
The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs, Nature Immunology, vol.195, issue.1, pp.76-82, 2006. ,
DOI : 10.1038/ni1293
Characterization of T Cell Differentiation in the Murine Gut, The Journal of Experimental Medicine, vol.5, issue.4, pp.437-449, 2002. ,
DOI : 10.1002/eji.1830270229
Major T Cell Progenitor Activity in Bone Marrow???derived Spleen Colonies, The Journal of Experimental Medicine, vol.189, issue.7, pp.919-929, 2002. ,
DOI : 10.1084/jem.20011475
The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages, Immunology Today, vol.20, issue.4, pp.184-189, 1999. ,
DOI : 10.1016/S0167-5699(99)01442-5
Regulation of B Versus T Lymphoid Lineage Fate Decision by the Proto-Oncogene LRF, Science, vol.316, issue.5826, pp.860-866, 2007. ,
DOI : 10.1126/science.1140881
Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation, Blood, vol.107, issue.9, pp.3511-3519, 2006. ,
DOI : 10.1182/blood-2005-08-3454
The diverse functions of histone lysine methylation, Nature Reviews Molecular Cell Biology, vol.15, issue.11, pp.838-849, 2005. ,
DOI : 10.1016/S1535-6108(02)00234-9
lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif, Cell, vol.58, issue.1, pp.77-83, 1989. ,
DOI : 10.1016/0092-8674(89)90404-2
Thymic T Cell Development and Progenitor Localization Depend on CCR7, The Journal of Experimental Medicine, vol.127, issue.4, pp.481-491, 2004. ,
DOI : 10.1023/A:1015320321511
RAG-1-deficient mice have no mature B and T lymphocytes, Cell, vol.68, issue.5, pp.869-877, 1992. ,
DOI : 10.1016/0092-8674(92)90030-G
Identification of a lineage of multipotent hematopoietic progenitors, Development, vol.124, pp.1929-1939, 1997. ,
The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype, Immunity, vol.1, issue.8, pp.661-673, 1994. ,
DOI : 10.1016/1074-7613(94)90037-X
Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow, Blood, vol.117, issue.24, pp.6552-6561, 2011. ,
DOI : 10.1182/blood-2010-12-323113
URL : https://hal.archives-ouvertes.fr/hal-00611505
Microenvironmental niches in the bone marrow required for B-cell development, Nature Reviews Immunology, vol.10, issue.2, pp.107-116, 2006. ,
DOI : 10.1038/nri1780
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor, Science, vol.262, issue.5141, pp.1877-1880, 1993. ,
DOI : 10.1126/science.8266077
Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment, Science, vol.333, issue.6039, pp.218-221, 2011. ,
DOI : 10.1126/science.1201219
The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche, Immunity, vol.33, issue.3, pp.387-399, 2010. ,
DOI : 10.1016/j.immuni.2010.08.017
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis, Nature Genetics, vol.19, issue.1, pp.40-44, 1995. ,
DOI : 10.1038/336348a0
Role of the gut as a primary lymphoid organ, Immunology Letters, vol.140, issue.1-2, pp.93-101, 2011. ,
DOI : 10.1016/j.imlet.2011.05.009
Quantification of Multiple Gene Expression in Individual Cells, Genome Research, vol.14, issue.10a, pp.1938-1947, 2004. ,
DOI : 10.1101/gr.2890204
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination, Immunity, vol.11, issue.3, pp.299-308, 1999. ,
DOI : 10.1016/S1074-7613(00)80105-3
Notch Signaling in the Immune System, Immunity, vol.32, issue.1, pp.14-27, 2010. ,
DOI : 10.1016/j.immuni.2010.01.004
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1, Immunity, vol.10, issue.5, pp.547-558, 1999. ,
DOI : 10.1016/S1074-7613(00)80054-0
A role for Wnt signalling in self-renewal of haematopoietic stem cells, Nature, vol.72, issue.6938, pp.409-414, 2003. ,
DOI : 10.1038/74546
Extrathymic T cell differentiation, Current Opinion in Immunology, vol.7, issue.2, pp.235-242, 1995. ,
DOI : 10.1016/0952-7915(95)80008-5
Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis, Blood, vol.106, issue.2, pp.477-484, 2005. ,
DOI : 10.1182/blood-2004-08-2989
Launching the T-cell-lineage developmental programme, Nature Reviews Immunology, vol.8, issue.1, pp.9-21, 2008. ,
DOI : 10.1038/nri2232
Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches, Science, vol.280, issue.5361, pp.275-278, 1998. ,
DOI : 10.1126/science.280.5361.275
Multiple extrathymic precursors contribute to T-cell development with different kinetics, Blood, vol.115, issue.6, pp.1137-1144, 2010. ,
DOI : 10.1182/blood-2009-07-230821
The relationship between the spleen colony-forming cell and the haemopoietic stem cell, Blood Cells, vol.4, pp.7-25, 1978. ,
Circulating hematopoietic progenitors with T lineage potential, Nature Immunology, vol.90, issue.9, pp.953-960, 2004. ,
DOI : 10.1038/23287
Early B Cell Factor Promotes B Lymphopoiesis with Reduced Interleukin 7 Responsiveness in the Absence of E2A, The Journal of Experimental Medicine, vol.15, issue.12, pp.1689-1700, 2004. ,
DOI : 10.1084/jem.194.5.645
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis, Blood, vol.113, issue.4, pp.807-815, 2009. ,
DOI : 10.1182/blood-2008-08-173682
T cell development in PU.1-deficient mice, J Immunol, vol.163, pp.2681-2687, 1999. ,
Purification and characterization of mouse hematopoietic stem cells, Science, vol.241, issue.4861, pp.58-62, 1988. ,
DOI : 10.1126/science.2898810
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome, Blood, vol.99, issue.7, pp.2369-2378, 2002. ,
DOI : 10.1182/blood.V99.7.2369
Expression of Functional P-Selectin Glycoprotein Ligand 1 on Hematopoietic Progenitors Is Developmentally Regulated, The Journal of Immunology, vol.188, issue.9, pp.4385-4393, 2012. ,
DOI : 10.4049/jimmunol.1101116
The Role of Osteoblasts in the Hematopoietic Microenvironment, Stem Cells, vol.159, issue.1, pp.7-15, 1998. ,
DOI : 10.1002/stem.160007
A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells, Radiation Research, vol.14, issue.2, pp.213-222, 1961. ,
DOI : 10.2307/3570892
Transcription factor GATA-3 is required for development of the T-cell lineage, Nature, vol.384, issue.6608, pp.474-478, 1996. ,
DOI : 10.1038/384474a0
An early haematopoietic defect in mice lacking the transcription factor
GATA-2, Nature, vol.371, issue.6494, pp.221-226, 1994. ,
DOI : 10.1038/371221a0
Adult T-cell progenitors retain myeloid potential, Nature, vol.194, issue.7188, pp.768-772, 2008. ,
DOI : 10.1038/nature06839
Two waves of recombinase gene expression in developing thymocytes, Journal of Experimental Medicine, vol.179, issue.4, pp.1355-1360, 1994. ,
DOI : 10.1084/jem.179.4.1355
Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gamma delta + gut intraepithelial lymphocytes, Blood, vol.98, issue.9, pp.2626-2632, 2001. ,
DOI : 10.1182/blood.V98.9.2626
Identification of Lin-Sca1+kit+CD34+Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients, Blood, vol.105, issue.7, pp.2717-2723, 2005. ,
DOI : 10.1182/blood-2004-06-2159
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A, Genes & Development, vol.23, issue.14, pp.1665-1676, 2009. ,
DOI : 10.1101/gad.1793709
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization, Nature, vol.400, pp.682-687, 1999. ,
Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus, The Journal of Immunology, vol.185, issue.1, pp.284-293, 2010. ,
DOI : 10.4049/jimmunol.1000679
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB., Molecular and Cellular Biology, vol.16, issue.6, pp.2-2, 1996. ,
DOI : 10.1128/MCB.16.6.2898
The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors, Nature Immunology, vol.17, issue.8, pp.761-769, 2012. ,
DOI : 10.1101/gad.1836009