M. J. Ackerman, S. G. Priori, S. Willems, C. Berul, R. Brugada et al., HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies, HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA), pp.1308-1339, 2011.
DOI : 10.1016/j.hrthm.2011.05.020

M. J. Ackerman, B. L. Siu, W. Q. Sturner, D. J. Tester, C. R. Valdivia et al., Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome, ACC Current Journal Review, vol.11, issue.2, pp.2264-2269, 2001.
DOI : 10.1016/S1062-1458(02)00588-3

M. J. Ackerman, D. J. Tester, and D. J. Driscoll, Molecular Autopsy of Sudden Unexplained Death in the Young, The American Journal of Forensic Medicine and Pathology, vol.22, issue.2, pp.105-111, 2001.
DOI : 10.1097/00000433-200106000-00001

M. J. Ackerman, D. J. Tester, C. J. Porter, and W. D. Edwards, Molecular Diagnosis of the Inherited Long-QT Syndrome in a Woman Who Died after Near-Drowning, New England Journal of Medicine, vol.341, issue.15, pp.1121-1125, 1999.
DOI : 10.1056/NEJM199910073411504

A. Akane, K. Matsubara, H. Nakamura, S. Takahashi, and K. Kimura, Identification of the Heme Compound Copurified with Deoxyribonucleic Acid (DNA) from Bloodstains, a Major Inhibitor of Polymerase Chain Reaction (PCR) Amplification, Journal of Forensic Sciences, vol.39, issue.2, pp.362-372, 1994.
DOI : 10.1520/JFS13607J

C. Allegue, Estudio genetico de la muerte subita cardiaca:Miocardioptia hipertrofica familiar y sindrome de QT largo, 2010.

C. Allegue, R. Gil, A. Blanco-verea, M. Santori, M. Rodriguez-calvo et al., Prevalence of HCM and long QT syndrome mutations in young sudden cardiac death-related cases, International Journal of Legal Medicine, vol.203, issue.1???3, pp.565-572, 2011.
DOI : 10.1007/s00414-011-0572-7

C. Allegue, R. Gil, P. Sanchez-diz, M. Torres, I. Quintela et al., A new approach to long QT syndrome mutation detection by Sequenom MassARRAY?? system, ELECTROPHORESIS, vol.2, issue.10, pp.1648-1655, 2010.
DOI : 10.1002/elps.201000022

M. Allouis, V. Probst, P. Jaafar, J. J. Schott, and H. L. Marec, Unusual clinical presentation in a family with catecholaminergic polymorphic ventricular tachycardia due to a G14876A ryanodine receptor gene mutation, The American Journal of Cardiology, vol.95, issue.5, pp.700-702, 2005.
DOI : 10.1016/j.amjcard.2004.10.057

S. E. Antonarakis, Recommendations for a nomenclature system for human gene mutations, Human Mutation, vol.8, issue.1, pp.1-3, 1998.
DOI : 10.1002/(SICI)1098-1004(1998)11:1<1::AID-HUMU1>3.0.CO;2-O

C. Antzelevitch, P. Brugada, M. Borggrefe, J. Brugada, R. Brugada et al., Brugada Syndrome: Report of the Second Consensus Conference: Endorsed by the Heart Rhythm Society and the European Heart Rhythm Association, Circulation, vol.111, issue.5, pp.659-670, 2005.
DOI : 10.1161/01.CIR.0000152479.54298.51

M. Arnestad, L. Crotti, T. O. Rognum, R. Insolia, M. Pedrazzini et al., Prevalence of Long-QT Syndrome Gene Variants in Sudden Infant Death Syndrome, Circulation, vol.115, issue.3, pp.361-367, 2007.
DOI : 10.1161/CIRCULATIONAHA.106.658021

A. Aydin, S. Bahring, S. Dahm, U. P. Guenther, R. Uhlmann et al., Single nucleotide polymorphism map of five long-QT genes, Journal of Molecular Medicine, vol.109, issue.2, pp.159-165, 2005.
DOI : 10.1007/s00109-004-0595-3

C. Basso, M. Burke, P. Fornes, P. J. Gallagher, R. H. De-gouveia et al., Guidelines for autopsy investigation of sudden cardiac death, Virchows Archiv, vol.104, issue.1, pp.11-18, 2008.
DOI : 10.1007/s00428-007-0505-5

C. Basso, F. Calabrese, D. Corrado, and G. Thiene, Postmortem diagnosis in sudden cardiac death victims: macroscopic, microscopic and molecular findings, Cardiovascular Research, vol.50, issue.2, pp.290-300, 2001.
DOI : 10.1016/S0008-6363(01)00261-9

R. Bastiaenen and E. R. Behr, Sudden death and ion channel disease: pathophysiology and implications for management, Heart, vol.97, issue.17, pp.1365-1372, 2011.
DOI : 10.1136/hrt.2011.223883

C. Bellocq, A. C. Van-ginneken, C. R. Bezzina, M. Alders, D. Escande et al., Mutation in the KCNQ1 Gene Leading to the Short QT-Interval Syndrome, Circulation, vol.109, issue.20, pp.2394-2397, 2004.
DOI : 10.1161/01.CIR.0000130409.72142.FE

G. Berecki, J. G. Zegers, Z. A. Bhuiyan, A. O. Verkerk, R. Wilders et al., Long-QT syndrome-related sodium channel mutations probed by the dynamic action potential clamp technique, The Journal of Physiology, vol.278, issue.Suppl. 1, pp.237-250, 2006.
DOI : 10.1113/jphysiol.2005.096578

K. E. Berge, K. H. Haugaa, A. Fruh, O. G. Anfinsen, K. Gjesdal et al., Molecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers, Scandinavian Journal of Clinical and Laboratory Investigation, vol.79, issue.1, pp.362-368, 2008.
DOI : 10.1016/j.hrthm.2005.07.012

J. Bloch, P. Denis, and D. Jezewski-serra, Enqu??te nationale sur les morts inattendues des nourrissons de moins de 2 ans, Archives de P??diatrie, vol.18, issue.5, p.56, 2007.
DOI : 10.1016/S0929-693X(11)71026-0

M. S. Bray, E. Boerwinkle, and P. A. Doris, High-throughput multiplex SNP genotyping with MALDI-TOF mass spectrometry: Practice, problems and promise, Human Mutation, vol.51, issue.4, pp.296-304, 2001.
DOI : 10.1002/humu.27

P. Brugada and J. Brugada, Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome, Journal of the American College of Cardiology, vol.20, issue.6, pp.1391-1396, 1992.
DOI : 10.1016/0735-1097(92)90253-J

R. Brugada, K. Hong, R. Dumaine, J. Cordeiro, F. Gaita et al., Sudden Death Associated With Short-QT Syndrome Linked to Mutations in HERG, Circulation, vol.109, issue.1, pp.30-35, 2004.
DOI : 10.1161/01.CIR.0000109482.92774.3A

W. Cao, M. Hashibe, J. Y. Rao, H. Morgenstern, and Z. F. Zhang, Comparison of methods for DNA extraction from paraffin-embedded tissues and buccal cells, Cancer Detection and Prevention, vol.27, issue.5, pp.397-404, 2003.
DOI : 10.1016/S0361-090X(03)00103-X

E. Carturan, D. J. Tester, B. C. Brost, C. Basso, G. Thiene et al., Postmortem Genetic Testing for Conventional Autopsy???Negative Sudden Unexplained Death, American Journal of Clinical Pathology, vol.129, issue.3, pp.391-397, 2008.
DOI : 10.1309/VLA7TT9EQ05FFVN4

M. Cerrone, B. Colombi, M. Bloise, C. Memmi, D. Monclavo et al., Clinical and molecular characterization of a large cohort of patients affected with catecholaminergic polymorphic ventricular tachycardia, pp.110-552, 2004.

G. Choi, L. J. Kopplin, D. J. Tester, M. L. Will, C. M. Haglund et al., Spectrum and Frequency of Cardiac Channel Defects in Swimming-Triggered Arrhythmia Syndromes, Circulation, vol.110, issue.15, pp.2119-2124, 2004.
DOI : 10.1161/01.CIR.0000144471.98080.CA

S. S. Chugh, O. Senashova, A. Watts, P. T. Tran, Z. Zhou et al., Postmortem molecular screening in unexplained sudden death, Journal of the American College of Cardiology, vol.43, issue.9, pp.1625-1629, 2004.
DOI : 10.1016/j.jacc.2003.11.052

S. D. Cohle and B. A. Sampson, The negative autopsy: Sudden cardiac death or other?, Cardiovascular Pathology, vol.10, issue.5, pp.219-222, 2001.
DOI : 10.1016/S1054-8807(01)00093-X

D. Corrado, C. Basso, and G. Thiene, Sudden cardiac death in young people with apparently normal heart, Cardiovascular Research, vol.50, issue.2, pp.399-408, 2001.
DOI : 10.1016/S0008-6363(01)00254-1

R. Coura, J. C. Prolla, L. Meurer, and P. Ashton-prolla, An alternative protocol for DNA extraction from formalin fixed and paraffin wax embedded tissue, Journal of Clinical Pathology, vol.58, issue.8, pp.894-895, 2005.
DOI : 10.1136/jcp.2004.021352

W. Creighton, R. Virmani, R. Kutys, and A. Burke, Identification of Novel Missense Mutations of Cardiac Ryanodine Receptor Gene in Exercise-Induced Sudden Death at Autopsy, The Journal of Molecular Diagnostics, vol.8, issue.1, pp.62-67, 2006.
DOI : 10.2353/jmoldx.2006.050081

L. Crotti, G. Celano, F. Dagradi, and P. J. Schwartz, Congenital long QT syndrome, Orphanet Journal of Rare Diseases, vol.3, issue.1, p.18, 2008.
DOI : 10.1186/1750-1172-3-18

J. J. De-vreede-swagemakers, A. P. Gorgels, W. I. Dubois-arbouw, J. W. Van-ree, M. J. Daemen et al., Out-of-Hospital Cardiac Arrest in the 1990s: A Population-Based Study in the Maastricht Area on Incidence, Characteristics and Survival, Journal of the American College of Cardiology, vol.30, issue.6, pp.1500-1505, 1997.
DOI : 10.1016/S0735-1097(97)00355-0

I. Denjoy, A. Maltret, and V. Probst, Syndrome du QT long cong??nital, tachycardie ventriculaire cat??cholergique, syndrome de Brugada et mort subite inexpliqu??e en p??diatrie, Archives of Cardiovascular Diseases Supplements, vol.4, issue.2, pp.179-192, 2012.
DOI : 10.1016/S1878-6480(12)70829-7
URL : http://doi.org/10.1016/s1878-6480(12)70829-7

D. Paolo, M. , D. Luchini, R. Bloise, and S. G. Priori, Postmortem Molecular Analysis in Victims of Sudden Unexplained Death, The American Journal of Forensic Medicine and Pathology, vol.25, issue.2, pp.182-184, 2004.
DOI : 10.1097/01.paf.0000127406.20447.8a

H. Do and A. Dobrovic, Limited copy number - high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies, Molecular Cancer, vol.8, issue.1, p.82, 2009.
DOI : 10.1186/1476-4598-8-82

H. Do and A. Dobrovic, Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase., Oncotarget, vol.3, issue.5, pp.546-558, 2012.
DOI : 10.18632/oncotarget.503

H. Do, M. Krypuy, P. L. Mitchell, S. B. Fox, and A. Dobrovic, High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies, BMC Cancer, vol.12, issue.8, p.142, 2008.
DOI : 10.1158/1078-0432.CCR-05-2845

H. Do, P. L. Solomon, S. B. Mitchell, A. Fox, and . Dobrovic, Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting, BMC Research Notes, vol.1, issue.1, p.14, 2008.
DOI : 10.1186/1756-0500-1-14

A. Doolan, N. Langlois, C. Chiu, J. Ingles, J. M. Lind et al., Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians, International Journal of Cardiology, vol.127, issue.1, pp.138-141, 2008.
DOI : 10.1016/j.ijcard.2007.05.001

A. Doolan, N. Langlois, and C. Semsarian, Causes of sudden cardiac death in young Australians, Med J Aust, vol.180, issue.3, pp.110-112, 2004.

Y. Drory, Y. Turetz, Y. Hiss, B. Lev, E. Z. Fisman et al., Sudden unexpected death in persons <40 years of age, The American Journal of Cardiology, vol.68, issue.13, pp.1388-1392, 1991.
DOI : 10.1016/0002-9149(91)90251-F

A. Farrugia and B. Ludes, Rôle de l'activité médico-légale dans la connaissance des morts violentes dans le Bas Rhin au cours de l'année, Numéro thématique « Médecine légale et santé publique : quelques éléments d'illustration, pp.40-41, 2008.

I. Ferrer, J. Armstrong, S. Capellari, P. Parchi, T. Arzberger et al., Effects of Formalin Fixation, Paraffin Embedding, and Time of Storage on DNA Preservation in Brain Tissue: A BrainNet Europe Study, Brain Pathology, vol.49, issue.3, pp.297-303, 2007.
DOI : 10.1097/00019606-200606000-00009

S. Gabriel, L. Ziaugra, and D. Tabbaa, SNP Genotyping Using the Sequenom MassARRAY iPLEX Platform, Curr Protoc Hum Genet Chapter, vol.357, issue.2, p.12, 2009.
DOI : 10.1002/0471142905.hg0212s60

M. T. Gilbert, A. J. Hansen, E. Willerslev, L. Rudbeck, I. Barnes et al., Characterization of Genetic Miscoding Lesions Caused by Postmortem Damage, The American Journal of Human Genetics, vol.72, issue.1, pp.48-61, 2003.
DOI : 10.1086/345379

M. T. Gilbert, T. Haselkorn, M. Bunce, J. J. Sanchez, S. B. Lucas et al., The Isolation of Nucleic Acids from Fixed, Paraffin-Embedded Tissues???Which Methods Are Useful When?, PLoS ONE, vol.35, issue.6, p.537, 2007.
DOI : 10.1371/journal.pone.0000537.s002

P. A. Gladding, C. A. Evans, J. Crawford, S. K. Chung, A. Vaughan et al., Posthumous diagnosis of long QT syndrome from neonatal screening cards, Heart Rhythm, vol.7, issue.4, pp.481-486, 2010.
DOI : 10.1016/j.hrthm.2009.12.023

S. E. Goelz, S. R. Hamilton, and B. Vogelstein, Purification of DNA from formaldehyde fixed and paraffin embedded human tissue, Biochemical and Biophysical Research Communications, vol.130, issue.1, pp.118-126, 1985.
DOI : 10.1016/0006-291X(85)90390-0

L. Gouas, V. Nicaud, M. Berthet, A. Forhan, L. Tiret et al., Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population, European Journal of Human Genetics, vol.103, issue.11, pp.1213-1222, 2005.
DOI : 10.1016/j.humimm.2003.08.347

W. G. Guntheroth and P. S. Spiers, The Triple Risk Hypotheses in Sudden Infant Death Syndrome, PEDIATRICS, vol.110, issue.5, p.64, 2002.
DOI : 10.1542/peds.110.5.e64

I. Gussak, P. Brugada, J. Brugada, R. S. Wright, S. L. Kopecky et al., Idiopathic Short QT Interval:A New Clinical Syndrome?, Cardiology, vol.94, issue.2, pp.99-102, 2000.
DOI : 10.1159/000047299

A. Hansen, E. Willerslev, C. Wiuf, T. Mourier, and P. Arctander, Statistical Evidence for Miscoding Lesions in Ancient DNA Templates, Molecular Biology and Evolution, vol.18, issue.2, pp.262-265, 2001.
DOI : 10.1093/oxfordjournals.molbev.a003800

P. L. Hedley, P. Jorgensen, S. Schlamowitz, R. Wangari, J. Moolman-smook et al., The genetic basis of long QT and short QT syndromes: A mutation update, Human Mutation, vol.281, issue.11, pp.1486-1511, 2009.
DOI : 10.1002/humu.21106

D. A. Heideman, F. B. Thunnissen, M. Doeleman, D. Kramer, H. M. Verheul et al., A panel of high resolution melting (HRM) technology-based assays with direct sequencing possibility for effective mutation screening of EGFR and K-ras genes, Cell Oncol, vol.31, issue.5, pp.329-333, 2009.

J. S. Hermida, J. L. Lemoine, F. B. Aoun, G. Jarry, J. L. Rey et al., Prevalence of the Brugada syndrome in an apparently healthy population, The American Journal of Cardiology, vol.86, issue.1, pp.91-94, 2000.
DOI : 10.1016/S0002-9149(00)00835-3

M. Hofreiter, V. Jaenicke, D. Serre, A. Haeseler-av, and S. Paabo, DNA sequences from multiple amplifications reveal artifacts induced by cytosine deamination in ancient DNA, Nucleic Acids Research, vol.29, issue.23, pp.4793-4799, 2001.
DOI : 10.1093/nar/29.23.4793

H. Horn, C. Pott, J. Kalla, M. Dreyling, A. Rosenwald et al., A multiplex MALDI-TOF MS approach facilitates genotyping of DNA from formalin-fixed paraffin-embedded tumour specimens, Pharmacogenetics and Genomics, vol.20, issue.10, pp.598-604, 2010.
DOI : 10.1097/FPC.0b013e32833deb16

H. Iwasa, I. T. Nagai, R. Nakamura, Y. Tanaka, and T. , Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population, Journal of Human Genetics, vol.45, issue.3, pp.182-183, 2000.
DOI : 10.1007/s100380050207

D. P. Jackson, F. A. Lewis, G. R. Taylor, A. W. Boylston, and P. Quirke, Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction., Journal of Clinical Pathology, vol.43, issue.6, pp.499-504, 1990.
DOI : 10.1136/jcp.43.6.499

A. Jervell and F. Lange-nielsen, Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval, and sudden death, American Heart Journal, vol.54, issue.1, pp.59-68, 1957.
DOI : 10.1016/0002-8703(57)90079-0

R. Jongbloed, C. Marcelis, C. Velter, P. Doevendans, J. Geraedts et al., DHPLC analysis of potassium ion channel genes in congenital long QT syndrome, Human Mutation, vol.17, issue.5, pp.382-391, 2002.
DOI : 10.1002/humu.10131

X. Jouven and D. Escande, [Sudden cardiac death: toward the identification of susceptibity genes], Arch Mal Coeur Vaiss, vol.99, issue.9, pp.806-812, 2006.

J. D. Kapplinger, D. J. Tester, M. Alders, B. Benito, M. Berthet et al., An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing, Heart Rhythm, vol.7, issue.1, pp.33-46, 2010.
DOI : 10.1016/j.hrthm.2009.09.069

S. Kauferstein, N. Kiehne, D. Erkapic, J. Schmidt, C. W. Hamm et al., A novel mutation in the cardiac ryanodine receptor gene (RyR2) in a patient with an unequivocal LQTS, International Journal of Cardiology, vol.146, issue.2, pp.249-250, 2011.
DOI : 10.1016/j.ijcard.2010.10.062

D. I. Keller, J. Grenier, G. Christe, F. Dubouloz, S. Osswald et al., Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures, Canadian Journal of Cardiology, vol.25, issue.8, pp.455-462, 2009.
DOI : 10.1016/S0828-282X(09)70117-5
URL : https://hal.archives-ouvertes.fr/inserm-00409709

C. Keyser-tracqui and B. Ludes, Methods for the Study of Ancient DNA, Methods Mol Biol, vol.297, pp.253-264, 2005.
DOI : 10.1385/1-59259-867-6:253

E. C. Klaver, G. M. Versluijs, and R. Wilders, Cardiac ion channel mutations in the sudden infant death syndrome, International Journal of Cardiology, vol.152, issue.2, pp.162-170, 2011.
DOI : 10.1016/j.ijcard.2010.12.051

A. Koop, P. Goldmann, S. R. Chen, R. Thieleczek, and M. Varsanyi, ARVC-Related Mutations in Divergent Region 3 Alter Functional Properties of the Cardiac Ryanodine Receptor, Biophysical Journal, vol.94, issue.12, pp.4668-4677, 2008.
DOI : 10.1529/biophysj.107.122382

H. F. Krous, J. B. Beckwith, R. W. Byard, T. O. Rognum, T. Bajanowski et al., Sudden Infant Death Syndrome and Unclassified Sudden Infant Deaths: A Definitional and Diagnostic Approach, PEDIATRICS, vol.114, issue.1, pp.234-238, 2004.
DOI : 10.1542/peds.114.1.234

M. Krypuy, A. A. Ahmed, D. Etemadmoghadam, S. J. Hyland, and G. , High resolution melting for mutation scanning of TP53exons 5???8, BMC Cancer, vol.47, issue.1-2, p.168, 2007.
DOI : 10.1016/S0165-022X(00)00153-6

B. N. Kudryavtsev, M. V. Kudryavtseva, G. A. Sakuta, and G. I. Stein, Human hepatocyte polyploidization kinetics in the course of life cycle, Virchows Archiv B Cell Pathology Including Molecular Pathology, vol.74, issue.1, pp.387-393, 1993.
DOI : 10.1007/BF02915139

H. C. Kung, D. L. Hoyert, J. Xu, and S. L. Murphy, Deaths, Veterinary Record, vol.171, issue.22, pp.1-120, 2005.
DOI : 10.1136/vr.e8087

H. Lahat, E. Pras, T. Olender, N. Avidan, E. Ben-asher et al., A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine-Induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel, The American Journal of Human Genetics, vol.69, issue.6, pp.1378-1384, 2001.
DOI : 10.1086/324565

L. P. Lai, Y. N. Su, F. J. Hsieh, F. T. Chiang, J. M. Juang et al., Denaturing high-performance liquid chromatography screening of the long QT syndrome-related cardiac sodium and potassium channel genes and identification of novel mutations and single nucleotide polymorphisms, Journal of Human Genetics, vol.12, issue.9, pp.490-496, 2005.
DOI : 10.1007/s10038-005-0283-3

P. J. Laitinen, K. M. Brown, K. Piippo, H. Swan, J. M. Devaney et al., Mutations of the Cardiac Ryanodine Receptor (RyR2) Gene in Familial Polymorphic Ventricular Tachycardia, Circulation, vol.103, issue.4, pp.485-490, 2001.
DOI : 10.1161/01.CIR.103.4.485

W. Lawler, The negative coroner's necropsy: a personal approach and consideration of difficulties., Journal of Clinical Pathology, vol.43, issue.12, pp.977-980, 1990.
DOI : 10.1136/jcp.43.12.977

M. Lee, H. R. Johnson, L. Feinberg, and A. , Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements, Nature Genetics, vol.384, issue.2, pp.181-185, 1997.
DOI : 10.1038/ng0297-181

A. Leenhardt, V. Lucet, I. Denjoy, F. Grau, D. D. Ngoc et al., Catecholaminergic Polymorphic Ventricular Tachycardia in Children : A 7-Year Follow-up of 21 Patients, Circulation, vol.91, issue.5, pp.1512-1519, 1995.
DOI : 10.1161/01.CIR.91.5.1512

R. R. Liberthson, Sudden Death from Cardiac Causes in Children and Young Adults, New England Journal of Medicine, vol.334, issue.16, pp.1039-1044, 1996.
DOI : 10.1056/NEJM199604183341607

T. Lindahl, Instability and decay of the primary structure of DNA, Nature, vol.362, issue.6422, pp.709-715, 1993.
DOI : 10.1038/362709a0

R. Loire, Mort subite, EMC - Cardiologie, vol.2, issue.3, 2007.
DOI : 10.1016/S1166-4568(07)45093-8

G. Lorin-de-la-grandmaison, I. Sibille, and M. Durigon, La levée de corps peut-elle être un substitut de principe à l'autopsie médico-légale, J Méd Lég Droit Méd, vol.44, pp.271-274, 2001.

E. S. Ma, C. L. Wong, F. B. Law, W. K. Chan, and D. Siu, Detection of KRAS mutations in colorectal cancer by high-resolution melting analysis, Journal of Clinical Pathology, vol.62, issue.10, pp.886-891, 2009.
DOI : 10.1136/jcp.2008.063677

B. J. Maron, Sudden Death in Young Athletes, New England Journal of Medicine, vol.349, issue.11, pp.1064-1075, 2003.
DOI : 10.1056/NEJMra022783

B. J. Maron, C. E. Clark, R. E. Goldstein, and S. E. Epstein, Potential role of QT interval prolongation in sudden infant death syndrome, Circulation, vol.54, issue.3, pp.423-430, 1976.
DOI : 10.1161/01.CIR.54.3.423

A. Medeiros-domingo, Z. A. Bhuiyan, D. J. Tester, N. Hofman, H. Bikker et al., The RYR2-Encoded Ryanodine Receptor/Calcium Release Channel in Patients Diagnosed Previously With Either Catecholaminergic Polymorphic Ventricular Tachycardia or Genotype Negative, Exercise-Induced Long QT Syndrome, Journal of the American College of Cardiology, vol.54, issue.22, pp.2065-2074, 2009.
DOI : 10.1016/j.jacc.2009.08.022

F. Mendisco, C. Keyser, C. Hollard, V. Seldes, A. E. Nielsen et al., Application of the iPLEX Gold SNP genotyping method for the analysis of Amerindian ancient DNA samples: benefits for ancient population studies, Electrophoresis, vol.32, pp.3-4, 2011.

K. Michaud, P. Mangin, and B. S. Elger, Genetic analysis of sudden cardiac death victims: a survey of current forensic autopsy practices, International Journal of Legal Medicine, vol.3, issue.1, pp.359-366, 2011.
DOI : 10.1007/s00414-010-0474-0

F. Miething, S. Hering, B. Hanschke, and J. Dressler, Effect of Fixation to the Degradation of Nuclear and Mitochondrial DNA in Different Tissues, Journal of Histochemistry & Cytochemistry, vol.17, issue.3, pp.371-374, 2006.
DOI : 10.1101/gr.1.1.46

G. Millat, V. Chanavat, H. Crehalet, and R. Rousson, Development of a high resolution melting method for the detection of genetic variations in Long QT Syndrome, Clinica Chimica Acta, vol.412, issue.1-2, pp.203-207, 2011.
DOI : 10.1016/j.cca.2010.09.013

G. Millat, V. Chanavat, C. Rodriguez-lafrasse, and R. Rousson, Rapid, sensitive and inexpensive detection of SCN5A genetic variations by high resolution melting analysis, Clinical Biochemistry, vol.42, issue.6, pp.491-499, 2009.
DOI : 10.1016/j.clinbiochem.2008.10.014

G. Millat, B. Kugener, P. Chevalier, M. Chahine, H. Huang et al., Contribution of Long-QT Syndrome Genetic Variants in Sudden Infant Death Syndrome, Pediatric Cardiology, vol.143, issue.4, pp.502-509, 2009.
DOI : 10.1007/s00246-009-9417-2

H. Milting, N. Lukas, B. Klauke, R. Korfer, A. Perrot et al., Composite polymorphisms in the ryanodine receptor 2 gene associated with arrhythmogenic right ventricular cardiomyopathy, Cardiovascular Research, vol.71, issue.3, pp.496-505, 2006.
DOI : 10.1016/j.cardiores.2006.04.004

A. Moretti, M. Bellin, A. Welling, C. B. Jung, J. T. Lam et al., Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome, New England Journal of Medicine, vol.363, issue.15, pp.1397-1409, 2010.
DOI : 10.1056/NEJMoa0908679

H. Morita, J. Wu, and D. P. Zipes, The QT syndromes: long and short, The Lancet, vol.372, issue.9640, pp.750-763, 2008.
DOI : 10.1016/S0140-6736(08)61307-0

C. Napolitano, S. G. Priori, P. J. Schwartz, R. Bloise, E. Ronchetti et al., Genetic Testing in the Long QT Syndrome, JAMA, vol.294, issue.23, pp.2975-2980, 2005.
DOI : 10.1001/jama.294.23.2975

L. Ning, A. Moss, W. Zareba, J. Robinson, S. Rosero et al., Denaturing High-Performance Liquid Chromatography Quickly and Reliably Detects Cardiac Ion Channel Mutations in Long QT Syndrome, Genetic Testing, vol.7, issue.3, pp.249-253, 2003.
DOI : 10.1089/109065703322537287

H. Nishio, M. Iwata, and K. Suzuki, Postmortem Molecular Screening for Cardiac Ryanodine Receptor Type 2 Mutations in Sudden Unexplained Death, Circulation Journal, vol.70, issue.11, pp.1402-1406, 2006.
DOI : 10.1253/circj.70.1402

H. Nishio, M. Kuwahara, H. Tsubone, Y. Koda, T. Sato et al., Identification of an ethnic-specific variant (V207M) of the KCNQ1 cardiac potassium channel gene in sudden unexplained death and implications from a knock-in mouse model, International Journal of Legal Medicine, vol.70, issue.3, pp.253-257, 2009.
DOI : 10.1007/s00414-009-0321-3

T. Otagiri, K. Kijima, M. Osawa, K. Ishii, N. Makita et al., Cardiac Ion Channel Gene Mutations in Sudden Infant Death Syndrome, Pediatric Research, vol.67, issue.5, pp.482-487, 2008.
DOI : 10.1203/PDR.0b013e3181841eca

L. D. Plant, P. N. Bowers, Q. Liu, T. Morgan, T. Zhang et al., A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y, Journal of Clinical Investigation, vol.116, issue.2, pp.430-435, 2006.
DOI : 10.1172/JCI25618DS1

F. Plenat, K. Montagne, N. Weinbreck, S. Corby, J. Champigneulle et al., Les cons??quences mol??culaires de la fixation et de l???inclusion: exemple des acides nucl??iques et des prot??ines, Annales de Pathologie, vol.26, issue.1, pp.8-21, 2006.
DOI : 10.1016/S0242-6498(06)70655-1

A. V. Postma, I. Denjoy, J. Kamblock, M. Alders, J. M. Lupoglazoff et al., Catecholaminergic polymorphic ventricular tachycardia: RYR2 mutations, bradycardia, and follow up of the patients, Journal of Medical Genetics, vol.42, issue.11, pp.863-870, 2005.
DOI : 10.1136/jmg.2004.028993

S. G. Priori and S. R. Chen, Inherited Dysfunction of Sarcoplasmic Reticulum Ca2+ Handling and Arrhythmogenesis, Circulation Research, vol.108, issue.7, pp.871-883, 2011.
DOI : 10.1161/CIRCRESAHA.110.226845

S. G. Priori, C. Napolitano, M. Memmi, B. Colombi, F. Drago et al., Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia, Circulation, vol.106, issue.1, pp.69-74, 2002.
DOI : 10.1161/01.CIR.0000020013.73106.D8

S. G. Priori, C. Napolitano, and P. J. Schwartz, Low Penetrance in the Long-QT Syndrome : Clinical Impact, Circulation, vol.99, issue.4, pp.529-533, 1999.
DOI : 10.1161/01.CIR.99.4.529

S. G. Priori, P. J. Schwartz, C. Napolitano, R. Bloise, E. Ronchetti et al., Risk Stratification in the Long-QT Syndrome, New England Journal of Medicine, vol.348, issue.19, pp.1866-1874, 2003.
DOI : 10.1056/NEJMoa022147

V. Probst, M. Allouis, F. Sacher, S. Pattier, D. Babuty et al., Progressive Cardiac Conduction Defect is the Prevailing Phenotype in Carriers of a Brugada Syndrome SCN5A Mutation, Journal of Cardiovascular Electrophysiology, vol.14, issue.3, pp.270-275, 2006.
DOI : 10.1161/01.CIR.0000160853.19867.61
URL : https://hal.archives-ouvertes.fr/hal-00750431

V. Probst, S. Evain, V. Gournay, A. Marie, J. J. Schott et al., Monomorphic Ventricular Tachycardia Due to Brugada Syndrome Successfully Treated by Hydroquinidine Therapy in a 3-Year-Old Child, Journal of Cardiovascular Electrophysiology, vol.23, issue.1, pp.97-100, 2006.
DOI : 10.1046/j.1460-9592.2002.01537.x

R. Puranik, C. K. Chow, J. A. Duflou, M. J. Kilborn, and M. A. Mcguire, Sudden death in the young, Heart Rhythm, vol.2, issue.12, pp.1277-1282, 2005.
DOI : 10.1016/j.hrthm.2005.09.008

N. Quach, M. F. Goodman, and D. Shibata, In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR, BMC Clinical Pathology, vol.155, issue.1, p.1, 2004.
DOI : 10.1016/S0002-9440(10)65461-2

G. Quatrehomme and D. Rouge, La recommandation N°R99(3) du Comité des ministres aux Etats membres du Conseil de l'Europe relatives à l'harmonisation des règles en matière d'autopsie légale, J Méd Lég Droit Méd, vol.46, pp.249-260, 2003.

C. Rambaud and M. C. Imbert, [Autopsy protocol in the sudden infant death syndrome (SIDS)], Ann Pathol, vol.13, issue.2, pp.131-134, 1993.

C. Romano, G. Gemme, and R. Pongiglione, [Rare Cardiac Arrythmias of the Pediatric Age. Ii. Syncopal Attacks Due to Paroxysmal Ventricular Fibrillation. (Presentation of 1st Case in Italian Pediatric Literature, Clin Pediatr, vol.45, pp.656-683, 1963.

N. Roux-buisson, M. Cacheux, A. Fourest-lieuvin, J. Fauconnier, J. Brocard et al., Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human, Human Molecular Genetics, vol.21, issue.12, pp.2759-2767, 2012.
DOI : 10.1093/hmg/dds104
URL : https://hal.archives-ouvertes.fr/inserm-00763211

J. E. Saffitz, Structural Heart Disease, SCN5A Gene Mutations, and Brugada Syndrome: A Complex Menage a Trois, Circulation, vol.112, issue.24, pp.3672-3674, 2005.
DOI : 10.1161/CIRCULATIONAHA.105.587147

R. Schimpf, U. Bauersfeld, F. Gaita, and C. Wolpert, Short QT syndrome, Cardiovascular Research, vol.67, issue.3, pp.416-417, 2005.
DOI : 10.1016/j.cardiores.2005.03.026

P. J. Schwartz, Cardiac sympathetic innervation and the sudden infant death syndrome, The American Journal of Medicine, vol.60, issue.2, pp.167-172, 1976.
DOI : 10.1016/0002-9343(76)90425-3

P. J. Schwartz, The congenital long QT syndromes from genotype to phenotype: clinical implications, Journal of Internal Medicine, vol.26, issue.1, pp.39-47, 2006.
DOI : 10.1161/01.CIR.0000125524.34234.13

P. J. Schwartz, S. G. Priori, R. Bloise, C. Napolitano, E. Ronchetti et al., Molecular diagnosis in a child with sudden infant death syndrome, The Lancet, vol.358, issue.9290, pp.1342-1343, 2001.
DOI : 10.1016/S0140-6736(01)06450-9

P. J. Schwartz, S. G. Priori, R. Dumaine, C. Napolitano, C. Antzelevitch et al., A Molecular Link between the Sudden Infant Death Syndrome and the Long-QT Syndrome, New England Journal of Medicine, vol.343, issue.4, pp.262-267, 2000.
DOI : 10.1056/NEJM200007273430405

P. J. Schwartz, S. G. Priori, C. Spazzolini, A. J. Moss, G. M. Vincent et al., Genotype-Phenotype Correlation in the Long-QT Syndrome : Gene-Specific Triggers for Life-Threatening Arrhythmias, Circulation, vol.103, issue.1, pp.89-95, 2001.
DOI : 10.1161/01.CIR.103.1.89

J. R. Skinner, J. Crawford, W. Smith, D. Aitken, C. A. Heaven et al., Prospective, population-based long QT molecular autopsy study of postmortem negative sudden death in 1 to 40 year olds, Heart Rhythm, vol.8, issue.3, pp.412-419, 2011.
DOI : 10.1016/j.hrthm.2010.11.016

L. M. Smith, J. Z. Sanders, R. J. Kaiser, P. Hughes, C. Dodd et al., Fluorescence detection in automated DNA sequence analysis, Nature, vol.13, issue.6071, pp.674-679, 1986.
DOI : 10.1038/321674a0

I. Splawski, J. Shen, K. W. Timothy, M. H. Lehmann, S. Priori et al., Spectrum of W, 2000.

O. C. Ward, A New Familial Cardiac Syndrome in Children, J Ir Med Assoc, vol.54, pp.103-106, 1964.

H. Wedekind, T. Bajanowski, P. Friederich, G. Breithardt, T. Wulfing et al., Sudden infant death syndrome and long QT syndrome: an epidemiological and genetic study, International Journal of Legal Medicine, vol.151, issue.suppl II, pp.129-137, 2006.
DOI : 10.1007/s00414-005-0019-0

E. Willerslev and A. Cooper, Review Paper. Ancient DNA, Proceedings of the Royal Society B: Biological Sciences, vol.272, issue.1558, pp.3-16, 1558.
DOI : 10.1098/rspb.2004.2813

C. Williams, F. Ponten, C. Moberg, P. Soderkvist, M. Uhlen et al., A High Frequency of Sequence Alterations Is Due to Formalin Fixation of Archival Specimens, The American Journal of Pathology, vol.155, issue.5, pp.1467-1471, 1999.
DOI : 10.1016/S0002-9440(10)65461-2

C. H. Wong, S. H. Koo, G. Q. She, P. Chui, and E. J. Lee, Genetic variability of RyR2 and CASQ2 genes in an Asian population, Forensic Science International, vol.192, issue.1-3, pp.1-3, 2009.
DOI : 10.1016/j.forsciint.2009.07.019

T. Yang, S. K. Chung, W. Zhang, J. G. Mullins, C. H. Mcculley et al., Biophysical Properties of 9 KCNQ1 Mutations Associated With Long-QT Syndrome, Circulation: Arrhythmia and Electrophysiology, vol.2, issue.4, pp.417-426, 2009.
DOI : 10.1161/CIRCEP.109.850149

W. Zareba, A. J. Moss, P. J. Schwartz, G. M. Vincent, J. L. Robinson et al., Influence of the Genotype on the Clinical Course of the Long-QT Syndrome, New England Journal of Medicine, vol.339, issue.14, pp.960-965, 1998.
DOI : 10.1056/NEJM199810013391404

D. P. Zipes and H. J. Wellens, Sudden Cardiac Death, Circulation, vol.98, issue.21, pp.2334-2351, 1998.
DOI : 10.1161/01.CIR.98.21.2334