Evaluation et prise en charge des processus de récupération en mémoire dans la maladie d’Alzheimer

Abstract : The main objective of this thesis was to evaluate retrieval memory processes in Alzheimer’s disease in order to develop innovative cognitive interventions. The first two studies focused on the characterization of these processes through performance evaluation of patients with Alzheimer’s disease in recognition memory tasks. The next two studies became interested in development of cognitive intervention programs aimed at reducing cognitive impairment and their impact. One tries to improve impaired cognitive processes from a cognitive training using the repetition-lag procedure and the other one uses different cognitive rehabilitation techniques that involve preserved cognitive processes to learn to resort to the use of external aids. The results showed a selective deficit in recognition processes in patients with a mild stage of Alzheimer’s disease, recollection would be particularly affected as familiarity remains preserved. In addition, source recognition deficit could be explained by a specific alteration of source recognition strategic processes whereas associative processes should remain preserved. Secondly, the experimental cognitive training program was effective, cognitive gains were objectified in transfer tasks. Similarly, the cognitive rehabilitation program using spaced retrieval technique and errorless learning has reduced the impact of cognitive impairment in everyday life
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Benjamin Boller. Evaluation et prise en charge des processus de récupération en mémoire dans la maladie d’Alzheimer. Psychologie. Université René Descartes - Paris V, 2012. Français. ⟨NNT : 2012PA05H113⟩. ⟨tel-00799712⟩

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