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Etude anatomique et fonctionnelle de l’innervation pelvipérinéale de la femme : cartographie tridimensionnelle de l’expression de la forme neurale de l’enzyme de synthèse de l’oxyde nitrique (nNOS)

Abstract : Anatomical knowledge is required for the development of surgical techniques,but little is known about the anatomy and physiology of innervation in the pelvic/perinealarea. The origin, perivisceral trajectory, anatomical relationships to organs and neighbouringvessels and of the endings of these nerves in the organs they control has not, to date, beeneasy to determine precisely by classical anatomical techniques based on the macroscopicdissection of cadavers. In the domain of pelvic cancer surgery, improvements in the quality oflife of patients are dependent on the preservation of these nervous system structures; themaintenance of function cannot be dissociated from oncological imperatives. Indeed, theintegrity of these nerves is essential for sphincter continence and sexual functions. Moststudies have focused on the functional sequelae of surgery in men. Very few studies havefocused exclusively on women, in whom sexual problems are more difficult to identify. Thereduction of such postsurgical functional problems thus requires a more completeunderstanding of the anatomy of the pelvic/perineal nervous system. This may be possiblethrough the use of new investigative techniques
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David Moszkowicz. Etude anatomique et fonctionnelle de l’innervation pelvipérinéale de la femme : cartographie tridimensionnelle de l’expression de la forme neurale de l’enzyme de synthèse de l’oxyde nitrique (nNOS). Médecine humaine et pathologie. Université Paris Sud - Paris XI, 2012. Français. ⟨NNT : 2012PA114836⟩. ⟨tel-00775860⟩

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