P. Adams, P. Afonine, G. Bunkoczi, V. Chen, I. Davis et al., : a comprehensive Python-based system for macromolecular structure solution, Acta Crystallographica Section D Biological Crystallography, vol.64, issue.2, pp.213-221, 2010.
DOI : 10.1107/S0907444909052925

B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts et al., Molecular biology of the cell: Garland Science, 2008.

G. Altenberg, The Engine of ABC Proteins, Physiology, vol.18, issue.5, pp.191-195, 2003.
DOI : 10.1152/nips.01445.2003

S. Amundsen and G. Smith, Interchangeable Parts of the Escherichia coli Recombination Machinery, Cell, vol.112, issue.6, pp.741-744, 2003.
DOI : 10.1016/S0092-8674(03)00197-1

A. Anderson, H. Nordan, R. Cain, G. Parrish, and D. Duggan, Studies on a Radio- Resistant Micrococcus .1. Isolation, Morphology, Cultural Characteristics, and Resistance to Gamma Radiation, Food Technology, vol.10, issue.12, pp.575-578, 1956.

N. Assenmacher and K. Hopfner, MRE11/RAD50/NBS1: complex activities, Chromosoma, vol.113, issue.4, pp.157-166, 2004.
DOI : 10.1007/s00412-004-0306-4

E. Aubert and C. Lecomte, Illustrated Fourier transforms for crystallography, Journal of Applied Crystallography, vol.40, issue.6, pp.1153-1165, 2007.
DOI : 10.1107/S0021889807043622

A. Bauermeister, R. Moeller, G. Reitz, S. Sommer, and P. Rettberg, Effect of Relative Humidity on Deinococcus radiodurans??? Resistance to Prolonged Desiccation, Heat, Ionizing, Germicidal, and Environmentally Relevant UV Radiation, Microbial Ecology, vol.46, issue.3, pp.715-722, 2011.
DOI : 10.1007/s00248-010-9785-4

URL : https://hal.archives-ouvertes.fr/hal-00574245

A. Baykov, O. Evtushenko, and S. Avaeva, A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay, Analytical Biochemistry, vol.171, issue.2, pp.266-270, 1988.
DOI : 10.1016/0003-2697(88)90484-8

E. Bentchikou, P. Servant, G. Coste, and S. Sommer, A Major Role of the RecFOR Pathway in DNA Double-Strand-Break Repair through ESDSA in Deinococcus radiodurans, PLoS Genetics, vol.184, issue.1, 2010.
DOI : 10.1371/journal.pgen.1000774.s004

URL : https://hal.archives-ouvertes.fr/hal-00506306

V. Bhaskara, A. Dupre, B. Lengsfeld, B. Hopkins, A. Chan et al., Rad50 Adenylate Kinase Activity Regulates DNA Tethering by Mre11/Rad50 Complexes, Molecular Cell, vol.25, issue.5, pp.647-661, 2007.
DOI : 10.1016/j.molcel.2007.01.028

URL : http://doi.org/10.1016/j.molcel.2007.01.028

M. Blasius, S. Sommer, and U. Hubscher, : What Belongs to the Survival Kit?, Critical Reviews in Biochemistry and Molecular Biology, vol.5, issue.3, pp.221-238, 2008.
DOI : 10.1046/j.1365-2958.2001.02479.x

S. Mcfarlan, J. Fredrickson, K. Minton, M. Zhai, L. Wackett et al., Outline of Crystallography for Biologist Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments, Nat Biotechnol, vol.18, issue.1, pp.85-90, 2000.

S. Burma, B. Chen, and D. Chen, Role of non-homologous end joining (NHEJ) in maintaining genomic integrity, DNA Repair, vol.5, issue.9-10, pp.9-10, 2006.
DOI : 10.1016/j.dnarep.2006.05.026

W. Burmeister, Structural changes in a cryo-cooled protein crystal owing to radiation damage, Acta Crystallographica Section D Biological Crystallography, vol.56, issue.3, pp.328-341, 2000.
DOI : 10.1107/S0907444999016261

P. Cardenas, T. Carzaniga, S. Zangrossi, F. Briani, E. Garcia-tirado et al., Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins, Nucleic Acids Research, vol.39, issue.21, pp.9250-9261, 2011.
DOI : 10.1093/nar/gkr635

URL : http://doi.org/10.1093/nar/gkr635

D. Carvin, S. Islam, M. Sternberg, and T. Blundell, The preparation of heavy-atom derivatives of protein crystals for use in multiple isomorphous replacement and anomalous scattering In International tables for Crystallography Protein crystallization: from purified protein to diffractionquality crystal, Crystallography of Biological macromolecules" E. RMaA Dordrecht: Kluwer Academic Chayen NE, Saridakis E Nat Methods, vol.5, issue.2, pp.247-262, 2001.

V. Chen, W. Arendall, J. Headd, D. Keedy, R. Immormino et al., : all-atom structure validation for macromolecular crystallography, Acta Crystallographica Section D Biological Crystallography, vol.285, issue.1, pp.12-21, 2010.
DOI : 10.1107/S0907444909042073

K. Chow and J. Courcelle, RecBCD and RecJ/RecQ Initiate DNA Degradation on Distinct Substrates in UV-Irradiated Escherichia coli, Radiation Research, vol.168, issue.4, pp.499-506, 2007.
DOI : 10.1667/RR1033.1

A. Ciccia and S. Elledge, The DNA Damage Response: Making It Safe to Play with Knives, Molecular Cell, vol.40, issue.2, pp.179-204, 2010.
DOI : 10.1016/j.molcel.2010.09.019

N. Cobbe and M. Heck, The Evolution of SMC Proteins: Phylogenetic Analysis and Structural Implications, Molecular Biology and Evolution, vol.21, issue.2, pp.332-347, 2004.
DOI : 10.1093/molbev/msh023

P. Coppens, The structure factor, International Tables for Crystallography, pp.10-24, 2006.

K. Cowtan, software for automated model building. 1. Tracing protein chains, Acta Crystallographica Section D Biological Crystallography, vol.62, issue.9, pp.1002-1011, 2006.
DOI : 10.1107/S0907444906022116

K. Cowtan, Recent developments in classical density modification, Acta Crystallographica Section D Biological Crystallography, vol.277, issue.4, pp.470-478, 2010.
DOI : 10.1107/S090744490903947X/ba5136sup1.txt

K. Cowtan and K. Zhang, Density modification for macromolecular phase improvement, Progress in Biophysics and Molecular Biology, vol.72, issue.3, 1999.
DOI : 10.1016/S0079-6107(99)00008-5

M. Cox, Motoring along with the bacterial RecA protein, Nature Reviews Molecular Cell Biology, vol.35, issue.2, pp.127-138, 2007.
DOI : 10.1038/nrm2099

M. Cox and J. Battista, Deinococcus radiodurans ??? the consummate survivor, Nature Reviews Microbiology, vol.47, issue.11, pp.882-892, 2005.
DOI : 10.1007/s007920050121

M. Cox, J. Keck, and J. Battista, Rising from the Ashes: DNA Repair in Deinococcus radiodurans, PLoS Genetics, vol.26, issue.1, 2010.
DOI : 10.1371/journal.pgen.1000815.g001

D. Amours and S. Jackson, The mre11 complex: at the crossroads of dna repair and checkpoint signalling, Nature Reviews Molecular Cell Biology, vol.3, issue.5, pp.317-327, 2002.
DOI : 10.1038/nrm805

M. Daly and K. Minton, Interchromosomal recombination in the extremely radioresistant bacterium Deinococcus radiodurans., Journal of Bacteriology, vol.177, issue.19, pp.5495-5505, 1995.
DOI : 10.1128/jb.177.19.5495-5505.1995

M. Daly and K. Minton, Recombination between a resident plasmid and the chromosome following irradiation of the radioresistant bacterium Deinococcus radiodurans, Gene, vol.187, issue.2, pp.225-229, 1997.
DOI : 10.1016/S0378-1119(96)00755-X

A. Davidson, E. Dassa, C. Orelle, and J. Chen, Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems, Microbiology and Molecular Biology Reviews, vol.72, issue.2, pp.317-364, 2008.
DOI : 10.1128/MMBR.00031-07

URL : https://hal.archives-ouvertes.fr/hal-00319506

D. Bont, R. Van-larebeke, and N. , Endogenous DNA damage in humans: a review of quantitative data, Mutagenesis, vol.19, issue.3, pp.169-185, 2004.
DOI : 10.1093/mutage/geh025

P. Debye, Molecular-weight Determination by Light Scattering., The Journal of Physical and Colloid Chemistry, vol.51, issue.1, pp.18-32, 1947.
DOI : 10.1021/j150451a002

M. Della, P. Palmbos, H. Tseng, L. Tonkin, J. Daley et al., Mycobacterial Ku and Ligase Proteins Constitute a Two-Component NHEJ Repair Machine, Science, vol.306, issue.5696, pp.683-685, 2004.
DOI : 10.1126/science.1099824

M. Dillingham, S. Kowalczykowski, D. Flot, F. Dupeux, and J. Marquez, RecBCD enzyme and the repair of doublestranded DNA breaks Expression, crystallization and X-ray data collection from microcrystals of the extracellular domain of the human inhibitory receptor expressed on myeloid cells IREM-1, Microbiol Mol Biol Rev Acta Crystallogr Sect F Struct Biol Cryst Commun, vol.72, issue.63, pp.642-671, 2007.

T. Dolinsky, P. Czodrowski, H. Li, J. Nielsen, J. Jensen et al., PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations, Nucleic Acids Research, vol.35, issue.Web Server, pp.522-525, 2007.
DOI : 10.1093/nar/gkm276

S. Doublie, [29] Preparation of selenomethionyl proteins for phase determination, Methods Enzymol, vol.276, pp.523-530, 1997.
DOI : 10.1016/S0076-6879(97)76075-0

A. Dupre, L. Boyer-chatenet, and J. Gautier, Two-step activation of ATM by DNA and the Mre11???Rad50???Nbs1 complex, Nature Structural & Molecular Biology, vol.1, issue.5, pp.451-457, 2006.
DOI : 10.1038/nsmb1090

P. Edman, Method for Determination of the Amino Acid Sequence in Peptides., Acta Chemica Scandinavica, vol.4, issue.3, p.475, 1949.
DOI : 10.3891/acta.chem.scand.04-0283

F. Elder, A. Gurewitsch, R. Langmuir, and H. Pollock, Radiation from Electrons in a Synchrotron, Physical Review, vol.71, issue.11, pp.829-830, 1947.
DOI : 10.1103/PhysRev.71.829.5

P. Emsley and K. Cowtan, : model-building tools for molecular graphics, Acta Crystallographica Section D Biological Crystallography, vol.60, issue.12, pp.2126-2132, 2004.
DOI : 10.1107/S0907444904019158

P. Evans, Scaling and assessment of data quality, Acta Crystallographica Section D Biological Crystallography, vol.62, issue.1, pp.72-82, 2006.
DOI : 10.1107/S0907444905036693

P. Evans and A. Mccoy, An introduction to molecular replacement, Acta Crystallographica Section D Biological Crystallography, vol.64, issue.1, pp.1-10, 2008.
DOI : 10.1107/S0907444907051554

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394790

K. Feeney, C. Wasson, and J. Parish, Cohesin: a regulator of genome integrity and gene expression, Biochemical Journal, vol.16, issue.2, pp.147-161, 2010.
DOI : 10.1093/hmg/ddn116

D. Flot, T. Mairs, T. Giraud, M. Guijarro, M. Lesourd et al., The ID23-2 structural biology microfocus beamline at the ESRF, Journal of Synchrotron Radiation, vol.5, issue.1, pp.107-118, 2010.
DOI : 10.1107/S0909049509041168

G. Friedel, The crystalline symmetries that can reveal the diffraction of Rontgen rays, Cr Hebd Acad Sci, vol.157, pp.1533-1536, 1913.

T. Funayama, I. Narumi, M. Kikuchi, S. Kitayama, H. Watanabe et al., Identification and disruption analysis of the recN gene in the extremely radioresistant bacterium Deinococcus radiodurans, Mutation Research/DNA Repair, vol.435, issue.2, pp.151-161, 1999.
DOI : 10.1016/S0921-8777(99)00044-0

J. Fuss and P. Cooper, DNA Repair: Dynamic Defenders against Cancer and Aging, PLoS Biology, vol.102, issue.6, p.203, 2006.
DOI : 10.1371/journal.pbio.0040203.t001

URL : http://doi.org/10.1371/journal.pbio.0040203

E. Garman and C. Nave, Radiation damage in protein crystals examined under various conditions by different methods, Journal of Synchrotron Radiation, vol.16, issue.2, pp.129-132, 2009.
DOI : 10.1107/S0909049509005238

E. Garman and R. Owen, Cryocooling and radiation damage in macromolecular crystallography, Acta Crystallographica Section D Biological Crystallography, vol.62, issue.1, pp.32-47, 2006.
DOI : 10.1107/S0907444905034207

R. Gentleman and R. Ihaka, Lexical Scope and Statistical Computing, Journal of Computational and Graphical Statistics, vol.5, issue.3, pp.491-508, 2000.
DOI : 10.1080/10618600.2000.10474895

D. Goodsell, The Molecular Perspective: Ultraviolet Light and Pyrimidine Dimers, Stem Cells, vol.286, issue.4, pp.348-349, 2001.
DOI : 10.1634/stemcells.19-4-348

P. Gouet, E. Courcelle, D. Stuart, and F. Metoz, ESPript: analysis of multiple sequence alignments in PostScript, Bioinformatics, vol.15, issue.4, pp.305-308, 1999.
DOI : 10.1093/bioinformatics/15.4.305

URL : https://hal.archives-ouvertes.fr/hal-00314288

M. Goujon, H. Mcwilliam, W. Li, F. Valentin, S. Squizzato et al., A new bioinformatics analysis tools framework at EMBL-EBI, Nucleic Acids Research, vol.38, issue.Web Server, pp.695-699, 2010.
DOI : 10.1093/nar/gkq313

P. Graumann and T. Knust, Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair, Chromosome Research, vol.18, issue.2, pp.265-275, 2009.
DOI : 10.1007/s10577-008-9014-x

J. Griese and K. Hopfner, Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain, Proteins: Structure, Function, and Bioinformatics, vol.16, issue.Pt 26, pp.558-568, 2011.
DOI : 10.1002/prot.22903

J. Griese, G. Witte, and K. Hopfner, Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins, Nucleic Acids Research, vol.38, issue.10, pp.3454-3465, 2010.
DOI : 10.1093/nar/gkq038

J. Grove, S. Wood, G. Briggs, N. Oldham, and R. Lloyd, A soluble RecN homologue provides means for biochemical and genetic analysis of DNA double-strand break repair in Escherichia coli, DNA Repair, vol.8, issue.12, pp.1434-1443, 2009.
DOI : 10.1016/j.dnarep.2009.09.015

S. Gruber, C. Haering, and K. Nasmyth, Chromosomal Cohesin Forms a Ring, Cell, vol.112, issue.6, pp.765-777, 2003.
DOI : 10.1016/S0092-8674(03)00162-4

C. Haering, D. Schoffnegger, T. Nishino, W. Helmhart, K. Nasmyth et al., Structure and Stability of Cohesin's Smc1-Kleisin Interaction, Molecular Cell, vol.15, issue.6, pp.951-964, 2004.
DOI : 10.1016/j.molcel.2004.08.030

P. Hanson and S. Whiteheart, AAA+ proteins: have engine, will work, Nature Reviews Molecular Cell Biology, vol.87, issue.7, pp.519-529, 2005.
DOI : 10.1074/jbc.274.37.26225

J. Harper and S. Elledge, The DNA Damage Response: Ten Years After, Molecular Cell, vol.28, issue.5, pp.739-745, 2007.
DOI : 10.1016/j.molcel.2007.11.015

S. Hauf, E. Roitinger, B. Koch, C. Dittrich, K. Mechtler et al., Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2, PLoS Biology, vol.376, issue.3, p.69, 2005.
DOI : 10.1371/journal.pbio.0030069.sg003

T. Helleday, E. Petermann, C. Lundin, B. Hodgson, and R. Sharma, DNA repair pathways as targets for cancer therapy, Nature Reviews Cancer, issue.8, pp.193-204, 2008.

J. Helliwell, Macromolecular crystallography with synchrotron radiation, 1992.
DOI : 10.1017/cbo9780511524264

W. Heyer, K. Ehmsen, and J. Liu, Regulation of Homologous Recombination in Eukaryotes, Annual Review of Genetics, vol.44, issue.1, pp.113-139, 2010.
DOI : 10.1146/annurev-genet-051710-150955

M. Hirano, D. Anderson, H. Erickson, and T. Hirano, Bimodal activation of SMC ATPase by intra- and inter-molecular interactions, The EMBO Journal, vol.20, issue.12, pp.3238-3250, 2001.
DOI : 10.1093/emboj/20.12.3238

M. Hirano and T. Hirano, ATP-dependent aggregation of single-stranded DNA by a bacterial SMC homodimer, The EMBO Journal, vol.76, issue.23, pp.7139-7148, 1998.
DOI : 10.1093/emboj/17.23.7139

M. Hirano and T. Hirano, Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA, The EMBO Journal, vol.21, issue.21, pp.5733-5744, 2002.
DOI : 10.1093/emboj/cdf575

M. Hirano and T. Hirano, Positive and negative regulation of SMC???DNA interactions by ATP and accessory proteins, The EMBO Journal, vol.13, issue.13, pp.2664-2673, 2004.
DOI : 10.1016/S0960-9822(02)00719-4

T. Hirano, The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair, Genes & Development, vol.16, issue.4, pp.399-414, 2002.
DOI : 10.1101/gad.955102

T. Hirano, SMC proteins and chromosome mechanics: from bacteria to humans, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.12, issue.6, pp.507-514, 1455.
DOI : 10.1016/S0960-9822(02)00719-4

T. Hirano, At the heart of the chromosome: SMC proteins in action, Nature Reviews Molecular Cell Biology, vol.16, issue.5, pp.311-322, 2006.
DOI : 10.1038/nrm1909

J. Hoeijmakers, Genome maintenance mechanisms for preventing cancer, Nature, vol.411, issue.6835, pp.366-374, 2001.
DOI : 10.1038/35077232

J. Hoeijmakers, DNA Damage, Aging, and Cancer, New England Journal of Medicine, vol.361, issue.15, pp.1475-1485, 2009.
DOI : 10.1056/NEJMra0804615

I. Holland and M. Blight, ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans, Journal of Molecular Biology, vol.293, issue.2, pp.381-399, 1999.
DOI : 10.1006/jmbi.1999.2993

K. Hollenstein, R. Dawson, and K. Locher, Structure and mechanism of ABC transporter proteins, Current Opinion in Structural Biology, vol.17, issue.4, pp.412-418, 2007.
DOI : 10.1016/j.sbi.2007.07.003

R. Holliday, A mechanism for gene conversion in fungi, Genetical Research, vol.3, issue.02, pp.282-304, 1964.
DOI : 10.1038/1911125b0

L. Holm, S. Kaariainen, P. Rosenstrom, and A. Schenkel, Searching protein structure databases with DaliLite v.3, Bioinformatics, vol.24, issue.23, pp.2780-2781, 2008.
DOI : 10.1093/bioinformatics/btn507

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639270

K. Hopfner, L. Craig, G. Moncalian, R. Zinkel, T. Usui et al., The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair, Nature, vol.150, issue.6897, pp.562-566, 2002.
DOI : 10.1016/S1097-2765(01)00270-2

K. Hopfner, A. Karcher, L. Craig, T. Woo, J. Carney et al., Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase, Cell, vol.105, issue.4, pp.473-485, 2001.
DOI : 10.1016/S0092-8674(01)00335-X

K. Hopfner, A. Karcher, D. Shin, L. Craig, L. Arthur et al., Structural Biology of Rad50 ATPase, Cell, vol.101, issue.7, pp.789-800, 2000.
DOI : 10.1016/S0092-8674(00)80890-9

K. Hopfner and J. Tainer, Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures, Current Opinion in Structural Biology, vol.13, issue.2, pp.249-255, 2003.
DOI : 10.1016/S0959-440X(03)00037-X

P. Huyghe, Conan the bacterium, Sciences-New York, vol.38, issue.4, pp.16-19, 1998.

J. Inoue, M. Honda, S. Ikawa, T. Shibata, and T. Mikawa, The process of displacing the single-stranded DNA-binding protein from single-stranded DNA by RecO and RecR proteins, Nucleic Acids Research, vol.36, issue.1, pp.94-109, 2008.
DOI : 10.1093/nar/gkm1004

A. Jackson, R. Chen, and L. Loeb, Induction of microsatellite instability by oxidative DNA damage, Proceedings of the National Academy of Sciences, vol.95, issue.21, pp.12468-12473, 1998.
DOI : 10.1073/pnas.95.21.12468

P. Jones and A. George, The ABC transporter structure and mechanism: perspectives on recent research, Cellular and Molecular Life Sciences (CMLS), vol.61, issue.6, pp.682-699, 2004.
DOI : 10.1007/s00018-003-3336-9

W. Kabsch, Integration, scaling, space-group assignment and post-refinement, Acta Crystallographica Section D Biological Crystallography, vol.34, issue.2, pp.133-144, 2010.
DOI : 10.1107/S0907444909047374

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815666

R. Kanaar and C. Wyman, DNA Repair by the MRN Complex: Break It to Make It, Cell, vol.135, issue.1, pp.14-16, 2008.
DOI : 10.1016/j.cell.2008.09.027

D. Kashchiev, Nucleation: basic theory with applications, 2000.

D. Kidane, H. Sanchez, J. Alonso, and P. Graumann, Visualization of DNA double-strand break repair in live bacteria reveals dynamic recruitment of Bacillus subtilis RecF, RecO and RecN proteins to distinct sites on the nucleoids, Molecular Microbiology, vol.4, issue.6, pp.1627-1639, 2004.
DOI : 10.1111/j.1365-2958.2004.04102.x

K. Kiianitsa, J. Solinger, and W. Heyer, NADH-coupled microplate photometric assay for kinetic studies of ATP-hydrolyzing enzymes with low and high specific activities, Analytical Biochemistry, vol.321, issue.2, pp.266-271, 2003.
DOI : 10.1016/S0003-2697(03)00461-5

J. Kim and M. Cox, The RecA proteins of Deinococcus radiodurans and Escherichia coli promote DNA strand exchange via inverse pathways, Proceedings of the National Academy of Sciences, vol.99, issue.12, pp.7917-7921, 2002.
DOI : 10.1073/pnas.122218499

E. Kinoshita, E. Van-der-linden, H. Sanchez, and C. Wyman, RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?, Chromosome Research, vol.11, issue.2, pp.277-288, 2009.
DOI : 10.1007/s10577-008-9018-6

P. Konarev, V. Volkov, A. Sokolova, M. Koch, and D. Svergun, : a Windows PC-based system for small-angle scattering data analysis, Journal of Applied Crystallography, vol.36, issue.5, pp.1277-1282, 2003.
DOI : 10.1107/S0021889803012779

O. Koroleva, N. Makharashvili, C. Courcelle, J. Courcelle, and S. Korolev, Structural conservation of RecF and Rad50: implications for DNA recognition and RecF function, The EMBO Journal, vol.433, issue.3, pp.867-877, 2007.
DOI : 10.1038/sj.emboj.7601537

M. Kozin and D. Svergun, Automated matching of high- and low-resolution structural models, Journal of Applied Crystallography, vol.34, issue.1, pp.33-41, 2001.
DOI : 10.1107/S0021889800014126

O. Kratky and G. Porod, Diffuse small-angle scattering of x-rays in colloid systems, Journal of Colloid Science, vol.4, issue.1, pp.35-70, 1949.
DOI : 10.1016/0095-8522(49)90032-X

A. Lammens, A. Schele, and K. Hopfner, Structural Biochemistry of ATP-Driven Dimerization and DNA-Stimulated Activation of SMC ATPases, Current Biology, vol.14, issue.19, pp.1778-1782, 2004.
DOI : 10.1016/j.cub.2004.09.044

K. Lammens, D. Bemeleit, C. Mockel, E. Clausing, A. Schele et al., The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair, Cell, vol.145, issue.1, pp.54-66, 2011.
DOI : 10.1016/j.cell.2011.02.038

G. Langer, S. Cohen, V. Lamzin, and A. Perrakis, Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7, Nature Protocols, vol.60, issue.7, pp.1171-1179, 2008.
DOI : 10.1038/nprot.2008.91

C. Lawrence, A. Borden, S. Banerjee, and J. Leclerc, Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector, Nucleic Acids Research, vol.18, issue.8, pp.2153-2157, 1990.
DOI : 10.1093/nar/18.8.2153

G. Li, Y. Xiang, Y. Zhang, and D. Wang, A simple and efficient innovation of the vapor-diffusion method for controlling nucleation and growth of large protein crystals, Journal of Applied Crystallography, vol.34, issue.3, pp.388-391, 2001.
DOI : 10.1107/S0021889801004666

Y. Li, A. Schoeffler, J. Berger, and M. Oakley, The Crystal Structure of the Hinge Domain of the Escherichia coli Structural Maintenance of Chromosomes Protein MukB, Journal of Molecular Biology, vol.395, issue.1, pp.11-19, 2010.
DOI : 10.1016/j.jmb.2009.10.040

H. Lim, J. Kim, Y. Park, G. Gwon, and Y. Cho, Crystal structure of the Mre11-Rad50-ATP??S complex: understanding the interplay between Mre11 and Rad50, Genes & Development, vol.25, issue.10, pp.1091-1104, 2011.
DOI : 10.1101/gad.2037811

M. Lisby, J. Barlow, R. Burgess, and R. Rothstein, Choreography of the DNA Damage Response, Cell, vol.118, issue.6, pp.699-713, 2004.
DOI : 10.1016/j.cell.2004.08.015

L. Liu, D. Hawkins, S. Ghosh, and S. Young, Robust singular value decomposition analysis of microarray data, Proceedings of the National Academy of Sciences, vol.100, issue.23, pp.13167-13172, 2003.
DOI : 10.1073/pnas.1733249100

M. Longhese, D. Bonetti, N. Manfrini, and M. Clerici, Mechanisms and regulation of DNA end resection, The EMBO Journal, vol.9, issue.17, pp.2864-2874, 2010.
DOI : 10.1534/genetics.104.027904

A. Losada and T. Hirano, Intermolecular DNA interactions stimulated by the cohesin complex in vitro, Current Biology, vol.11, issue.4, pp.268-272, 2001.
DOI : 10.1016/S0960-9822(01)00066-5

J. Lowe, S. Cordell, and F. Van-den-ent, Crystal structure of the SMC head domain: an ABC ATPase with 900 residues antiparallel coiled-coil inserted11Edited by R. Huber, Journal of Molecular Biology, vol.306, issue.1, pp.25-35, 2001.
DOI : 10.1006/jmbi.2000.4379

S. Lusetti and M. Cox, The Bacterial RecA Protein and the Recombinational DNA Repair of Stalled Replication Forks, Annual Review of Biochemistry, vol.71, issue.1, pp.71-100, 2002.
DOI : 10.1146/annurev.biochem.71.083101.133940

V. Mattimore and J. Battista, Radioresistance of Deinococcus radiodurans: functions necessary to survive ionizing radiation are also necessary to survive prolonged desiccation., Journal of Bacteriology, vol.178, issue.3, pp.633-637, 1996.
DOI : 10.1128/jb.178.3.633-637.1996

A. Mccarthy, S. Brockhauser, D. Nurizzo, P. Theveneau, T. Mairs et al., A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF, Journal of Synchrotron Radiation, vol.16, issue.6, pp.803-812, 2009.
DOI : 10.1107/S0909049509035377

A. Mccoy, R. Grosse-kunstleve, P. Adams, M. Winn, L. Storoni et al., crystallographic software, Journal of Applied Crystallography, vol.40, issue.4, pp.658-674, 2007.
DOI : 10.1107/S0021889807021206

C. Mockel, K. Lammens, A. Schele, and K. Hopfner, ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex, Nucleic Acids Research, vol.40, issue.2, 2011.
DOI : 10.1093/nar/gkr749

J. Moore and J. Haber, Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.16, issue.5, pp.2164-2173, 1996.
DOI : 10.1128/MCB.16.5.2164

F. Moreno-herrero, M. De-jager, N. Dekker, R. Kanaar, C. Wyman et al., Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA, Nature, vol.437, issue.7057, pp.440-443, 2005.
DOI : 10.1038/nature03927

K. Morimatsu and S. Kowalczykowski, RecFOR Proteins Load RecA Protein onto Gapped DNA to Accelerate DNA Strand Exchange, Molecular Cell, vol.11, issue.5, pp.1337-1347, 2003.
DOI : 10.1016/S1097-2765(03)00188-6

URL : http://doi.org/10.1016/s1097-2765(03)00188-6

Y. Murayama, Y. Kurokawa, K. Mayanagi, and H. Iwasaki, Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases, Nature, vol.5, issue.7181, pp.1018-1021, 2008.
DOI : 10.1038/nature06609

G. Murshudov, P. Skubak, A. Lebedev, N. Pannu, R. Steiner et al., 5 for the refinement of macromolecular crystal structures, Acta Crystallographica Section D Biological Crystallography, vol.57, issue.4, pp.355-367, 2011.
DOI : 10.1107/S0907444911001314

G. Murshudov, A. Vagin, and E. Dodson, Refinement of Macromolecular Structures by the Maximum-Likelihood Method, Acta Crystallographica Section D Biological Crystallography, vol.53, issue.3, pp.240-255, 1997.
DOI : 10.1107/S0907444996012255

J. Nakamura and J. Swenberg, Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues, Cancer Res, vol.59, issue.11, pp.2522-2526, 1999.

K. Nasmyth, C. Haering, J. Lowe, and A. Hochwagen, Molecular architecture of SMC proteins and the yeast cohesin complex, Molecular Cell, vol.9, issue.4, pp.773-788, 2002.

H. Niki, R. Imamura, M. Kitaoka, K. Yamanaka, T. Ogura et al., E.coli MukB protein involved in chromosome partition forms a homodimer with a rod-and-hinge structure having DNA binding and ATP/GTP binding activities, EMBO J, vol.11, issue.13, pp.5101-5109, 1992.

U. Nobbman, M. Connah, B. Fish, P. Varley, C. Gee et al., Dynamic light scattering as a relative tool for assessing the molecular integrity and stability of monoclonal antibodies, Biotechnology and Genetic Engineering Reviews, vol.27, issue.1, pp.117-128, 2007.
DOI : 10.1080/02648725.2007.10648095

D. Nurizzo, T. Mairs, M. Guijarro, V. Rey, J. Meyer et al., The ID23-1 structural biology beamline at the ESRF, Journal of Synchrotron Radiation, vol.13, issue.3, pp.227-238, 2006.
DOI : 10.1107/S0909049506004341

P. Ordoukhanian and J. Taylor, Caged Single and Double Strand Breaks, Bioconjugate Chemistry, vol.11, issue.1, pp.94-103, 2000.
DOI : 10.1021/bc9900993

J. Painter and E. Merritt, Optimal description of a protein structure in terms of multiple groups undergoing TLS motion, Acta Crystallographica Section D Biological Crystallography, vol.62, issue.4, pp.439-450, 2006.
DOI : 10.1107/S0907444906005270/sx5049sup1.pdf

S. Panjikar, V. Parthasarathy, V. Lamzin, M. Weiss, and P. Tucker, : an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment, Acta Crystallographica Section D Biological Crystallography, vol.61, issue.4, pp.449-457, 2005.
DOI : 10.1107/S0907444905001307

T. Paull, G. Moncalian, B. Lengsfeld, V. Bhaskara, K. Hopfner et al., The Rad50 signature motif: Essential to ATP binding and biological function, Journal of Molecular Biology, vol.335, issue.4, pp.937-951, 2004.

S. Pellegrino, D. De-sanctis, S. Mcsweeney, and J. Timmins, Expression, purification and preliminary structural analysis of the coiled-coil domain of Deinococcus radiodurans RecN, Acta Crystallogr F, 2011.

S. Pellegrino, D. De-sanctis, S. Mcsweeney, and J. Timmins, RecN, Acta Crystallographica Section F Structural Biology and Crystallization Communications, vol.36, issue.2, pp.218-221, 2012.
DOI : 10.1107/S1744309111055187

URL : https://hal.archives-ouvertes.fr/tel-00769957

S. Pellegrino, J. Radzimanowski, D. De-sanctis, S. Mcsweeney, and J. Timmins, submitted) Structural and functional characterization of RecN: New insights into double-strand break repair, Nucleic Acids Res, 2012.

S. Pellegrino, J. Radzimanowski, S. Mcsweeney, and J. Timmins, Expression, purification and preliminary structural analysis of the head domain of Deinococcus radiodurans RecN, 2012.

S. Pellegrino, J. Radzimanowski, S. Mcsweeney, and J. Timmins, RecN, Acta Crystallographica Section F Structural Biology and Crystallization Communications, vol.584, issue.1, pp.81-84, 2012.
DOI : 10.1107/S1744309111048743

URL : https://hal.archives-ouvertes.fr/tel-00769957

P. Pernot, P. Theveneau, T. Giraud, R. Fernandes, D. Nurizzo et al., New beamline dedicated to solution scattering from biological macromolecules at the ESRF, Xiv International Conference on Small-Angle Scattering, p.247, 2010.
DOI : 10.1088/1742-6596/247/1/012009

M. Petoukhov, P. Konarev, A. Kikhney, and D. Svergun, 2.1 ??? towards automated and web-supported small-angle scattering data analysis, Journal of Applied Crystallography, vol.40, issue.s1, pp.223-228, 2007.
DOI : 10.1107/S0021889807002853

URL : https://hal.archives-ouvertes.fr/hal-00326457

C. Putnam, M. Hammel, G. Hura, and J. Tainer, X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution, Quarterly Reviews of Biophysics, vol.52, issue.03, pp.191-285, 2007.
DOI : 10.1016/j.str.2007.02.007

M. Radman, D. Slade, A. Lindner, and G. Paul, Recombination and Replication in DNA Repair of Heavily Irradiated Deinococcus radiodurans, Cell, vol.136, issue.6, pp.1044-1055, 2009.

S. Rao and M. Rossmann, Comparison of super-secondary structures in proteins, Journal of Molecular Biology, vol.76, issue.2, p.241, 1973.
DOI : 10.1016/0022-2836(73)90388-4

R. Ravelli and S. Mcsweeney, The ???fingerprint??? that X-rays can leave on structures, Structure, vol.8, issue.3, pp.315-328, 2000.
DOI : 10.1016/S0969-2126(00)00109-X

D. Rees, E. Johnson, and O. Lewinson, ABC transporters: the power to change, Nature Reviews Molecular Cell Biology, vol.41, issue.3, pp.218-227, 2009.
DOI : 10.1038/nrm2646

E. Reyes, P. Patidar, L. Uranga, A. Bortoletto, and S. Lusetti, RecN Is a Cohesin-like Protein That Stimulates Intermolecular DNA Interactions in Vitro, Journal of Biological Chemistry, vol.285, issue.22, pp.16521-16529, 2010.
DOI : 10.1074/jbc.M110.119164

E. Rocha, E. Cornet, and B. Michel, Comparative and Evolutionary Analysis of the Bacterial Homologous Recombination Systems, PLoS Genetics, vol.188, issue.2, p.15, 2005.
DOI : 0378-1097(2000)188[0209:COGAGC]2.0.CO;2

A. Royant, P. Carpentier, J. Ohana, J. Mcgeehan, B. Paetzold et al., Advances in spectroscopic methods for biological crystals. 1. Fluorescence lifetime measurements, Journal of Applied Crystallography, vol.40, issue.6, pp.1105-1112, 2007.
DOI : 10.1107/S0021889807044196

S. Russi, D. Juers, J. Sanchez-weatherby, E. Pellegrini, E. Mossou et al., Inducing phase changes in crystals of macromolecules: Status and perspectives for controlled crystal dehydration, Journal of Structural Biology, vol.175, issue.2, pp.236-243, 2011.
DOI : 10.1016/j.jsb.2011.03.002

K. Saikrishnan, B. Powell, N. Cook, M. Webb, and D. Wigley, Mechanistic Basis of 5???-3??? Translocation in SF1B Helicases, Cell, vol.137, issue.5, pp.849-859, 2009.
DOI : 10.1016/j.cell.2009.03.036

A. Sakai and M. Cox, RecFOR and RecOR as Distinct RecA Loading Pathways, Journal of Biological Chemistry, vol.284, issue.5, pp.3264-3272, 2009.
DOI : 10.1074/jbc.M807220200

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631980

J. Sambrook, E. Fritsch, and T. Maniatis, Molecular Cloning: A Laboratory Manual, 1989.

H. Sanchez and J. Alonso, Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP, Nucleic Acids Research, vol.33, issue.7, pp.2343-2350, 2005.
DOI : 10.1093/nar/gki533

Y. Savir and T. Tlusty, RecA-Mediated Homology Search as a Nearly Optimal Signal Detection System, Molecular Cell, vol.40, issue.3, pp.388-396, 2010.
DOI : 10.1016/j.molcel.2010.10.020

D. Schatz and E. Spanopoulou, Biochemistry of V(D)J Recombination, Curr Top Microbiol Immunol, vol.290, pp.49-85, 2005.
DOI : 10.1007/3-540-26363-2_4

M. Schwartz, L. Shapiro, G. Sharples, S. Ingleston, and R. Lloyd, An SMC ATPase mutant disrupts chromosome segregation in Caulobacter Holliday junction processing in bacteria: Insights from the evolutionary conservation of RuVABC, RecG, and RusA, Mol Microbiol Journal of Bacteriology, vol.181, issue.18, pp.5543-5550, 1999.

G. Sheldrick, : combining chain tracing with density modification, Acta Crystallographica Section D Biological Crystallography, vol.46, issue.4, pp.479-485, 2010.
DOI : 10.1107/S0907444909038360

K. Shintomi and T. Hirano, How are cohesin rings opened and closed?, Trends in Biochemical Sciences, vol.32, issue.4, pp.154-157, 2007.
DOI : 10.1016/j.tibs.2007.02.002

S. Shuman and M. Glickman, Bacterial DNA repair by non-homologous end joining, Nature Reviews Microbiology, vol.189, issue.11, pp.852-861, 2007.
DOI : 10.1038/nrmicro1768

M. Singleton, M. Dillingham, M. Gaudier, S. Kowalczykowski, and D. Wigley, Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks, Nature, vol.54, issue.7014, pp.187-193, 2004.
DOI : 10.1016/S0076-6879(97)77028-9

R. Sinha and D. Hader, UV-induced DNA damage and repair: a review, Photochemical & Photobiological Sciences, vol.1, issue.4, pp.225-236, 2002.
DOI : 10.1039/b201230h

D. Slade and M. Radman, Oxidative Stress Resistance in Deinococcus radiodurans, Microbiology and Molecular Biology Reviews, vol.75, issue.1, pp.133-191, 2011.
DOI : 10.1128/MMBR.00015-10

M. Spies, S. Kowalczykowski, . Jm, and J. Harper, Homologous recombination by RecBCD and RecF pathways GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution, Bacterial Chromosomes, pp.389-403, 2004.

D. Svergun, C. Barberato, and M. Koch, ??? a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates, Journal of Applied Crystallography, vol.28, issue.6, pp.768-773, 1995.
DOI : 10.1107/S0021889895007047

D. Svergun, Determination of the regularization parameter in indirect-transform methods using perceptual criteria, Journal of Applied Crystallography, vol.25, issue.4, pp.495-503, 1992.
DOI : 10.1107/S0021889892001663

D. Svergun, Restoring Low Resolution Structure of Biological Macromolecules from Solution Scattering Using Simulated Annealing, Biophysical Journal, vol.76, issue.6, pp.2896-2896, 1999.
DOI : 10.1016/S0006-3495(99)77443-6

D. Svergun, P. Konarev, and M. Petoukhov, MASSHA -a graphics system for rigidbody modelling of macromolecular complexes against solution scattering data, J Appl Crystallogr, vol.34, pp.527-532, 2001.

D. Svergun and M. Kozin, Automated matching of high-and low-resolution structural models, J Appl Crystallogr, vol.34, pp.33-41, 2001.

D. Svergun, M. Petoukhov, and M. Koch, Determination of Domain Structure of Proteins from X-Ray Solution Scattering, Biophysical Journal, vol.80, issue.6, pp.2946-2953, 2001.
DOI : 10.1016/S0006-3495(01)76260-1

M. Tanaka, A. Earl, H. Howell, M. Park, J. Eisen et al., Analysis of Deinococcus radiodurans's Transcriptional Response to Ionizing Radiation and Desiccation Reveals Novel Proteins That Contribute to Extreme Radioresistance, Genetics, vol.168, issue.1, pp.21-33, 2004.
DOI : 10.1534/genetics.104.029249

A. Taylor and G. Smith, Regulation of homologous recombination: Chi inactivates RecBCD enzyme by disassembly of the three subunits, Genes & Development, vol.13, issue.7, pp.890-900, 1999.
DOI : 10.1101/gad.13.7.890

G. Taylor, The phase problem, Acta Crystallographica Section D Biological Crystallography, vol.59, issue.11, pp.1881-1890, 2003.
DOI : 10.1107/S0907444903017815

G. Taylor, Introduction to phasing, Acta Crystallographica Section D Biological Crystallography, vol.59, issue.4, pp.325-338, 2010.
DOI : 10.1107/S0907444910006694

T. Terwilliger, Maximum-likelihood density modification, Acta Crystallographica Section D Biological Crystallography, vol.56, issue.8, pp.965-972, 2000.
DOI : 10.1107/S0907444900005072

T. Terwilliger, Automated main-chain model building by template matching and iterative fragment extension, Acta Crystallographica Section D Biological Crystallography, vol.59, issue.1, pp.38-44, 2003.
DOI : 10.1107/S0907444902018036

T. Terwilliger, P. Adams, R. Read, A. Mccoy, N. Moriarty et al., wizard, Acta Crystallographica Section D Biological Crystallography, vol.65, issue.6, pp.582-601, 2009.
DOI : 10.1107/S0907444909012098

T. Terwilliger, R. Grosse-kunstleve, P. Afonine, N. Moriarty, P. Zwart et al., wizard, Acta Crystallographica Section D Biological Crystallography, vol.64, issue.1, pp.61-69, 2008.
DOI : 10.1107/S090744490705024X

J. Timmins, E. Gordon, C. S. Leonard, G. Acajjaoui, S. Kuo et al., Structural and Mutational Analyses of Deinococcus radiodurans UvrA2 Provide Insight into DNA Binding and Damage Recognition by UvrAs, Structure, vol.17, issue.4, pp.547-558, 2009.
DOI : 10.1016/j.str.2009.02.008

A. Tomkinson, L. Chen, K. Trujillo, S. Van-komen, D. Roh et al., Effect of amino acid substitutions in the Rad50 ATP binding domain on DNA double strand break repair in yeast, Journal of Biological Chemistry, vol.280, issue.4, pp.2620-2627, 2005.

A. Vagin and A. Teplyakov, : an Automated Program for Molecular Replacement, Journal of Applied Crystallography, vol.30, issue.6, pp.1022-1025, 1997.
DOI : 10.1107/S0021889897006766

J. Van-noort, T. Van-der-heijden, M. De-jager, C. Wyman, R. Kanaar et al., The coiled-coil of the human Rad50 DNA repair protein contains specific segments of increased flexibility, Proceedings of the National Academy of Sciences, vol.100, issue.13, pp.7581-7586, 2003.
DOI : 10.1073/pnas.1330706100

V. Volkov and D. Svergun, shape determination in small-angle scattering, Journal of Applied Crystallography, vol.36, issue.3, pp.860-864, 2003.
DOI : 10.1107/S0021889803000268

S. Wakatsuki, H. Belrhali, E. Mitchell, W. Burmeister, S. Mcsweeney et al., ID14 `Quadriga', a Beamline for Protein Crystallography at the ESRF, Journal of Synchrotron Radiation, vol.5, issue.3, pp.215-221, 1998.
DOI : 10.1107/S0909049597018785

J. Walker, M. Saraste, M. Runswick, and N. Gay, Distantly related sequences in the alphaand beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold, EMBO J, vol.1, issue.8, pp.945-951, 1982.

H. Wang, A. Perrault, Y. Takeda, W. Qin, and G. Iliakis, Biochemical evidence for Ku-independent backup pathways of NHEJ, Nucleic Acids Research, vol.31, issue.18, pp.5377-5388, 2003.
DOI : 10.1093/nar/gkg728

E. Watrin and J. Peters, Cohesin and DNA damage repair, Experimental Cell Research, vol.312, issue.14, pp.2687-2693, 2006.
DOI : 10.1016/j.yexcr.2006.06.024

J. Watson and F. Crick, Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid, Nature, vol.9, issue.4356, pp.737-738, 1953.
DOI : 10.1016/0006-3002(53)90232-7

O. White, J. Eisen, J. Heidelberg, E. Hickey, J. Peterson et al., Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1, Science, vol.286, issue.5444, pp.1571-1577, 1999.
DOI : 10.1126/science.286.5444.1571

M. Wilkins, E. Gasteiger, A. Bairoch, J. Sanchez, K. Williams et al., Protein Identification and Analysis Tools in the ExPASy Server, Methods Mol Biol, vol.112, pp.531-552, 1999.
DOI : 10.1385/1-59259-584-7:531

G. Williams, R. Williams, J. Williams, G. Moncalian, A. Arvai et al., ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair, Nature Structural & Molecular Biology, vol.66, issue.4, pp.423-454, 2011.
DOI : 10.1016/S0378-1119(03)00402-5

R. Williams, G. Moncalian, J. Williams, Y. Yamada, O. Limbo et al., Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair, Cell, vol.135, issue.1, pp.97-109, 2008.
DOI : 10.1016/j.cell.2008.08.017

M. Williamson, The structure and function of proline-rich regions in proteins, Biochemical Journal, vol.297, issue.2, pp.249-260, 1994.
DOI : 10.1042/bj2970249

R. Wong, An update on cohesin function as a ???molecular glue??? on chromosomes and spindles, Cell Cycle, vol.9, issue.9, pp.1754-1758, 2010.
DOI : 10.4161/cc.9.9.11806

C. Wyman, E. Kinoshita, E. Van-der-linden, and H. Sanchez, RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?, Chromosome Res, vol.17, issue.2, pp.277-288, 2009.

C. Wyman, D. Ristic, and R. Kanaar, Homologous recombination-mediated double-strand break repair, DNA Repair, vol.3, issue.8-9, pp.8-9, 2004.
DOI : 10.1016/j.dnarep.2004.03.037

J. Xie, L. Wang, N. Wu, A. Brock, G. Spraggon et al., The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination, Nature Biotechnology, vol.10, issue.10, pp.1297-1301, 2004.
DOI : 10.1016/S1093-3263(97)00021-1

M. Yabuki, M. Fujii, and N. Maizels, The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions, Nature Immunology, vol.13, issue.7, pp.730-736, 2005.
DOI : 10.1016/S0960-9822(99)80427-8

K. Zahradka, D. Slade, A. Bailone, S. Sommer, D. Averbeck et al., Reassembly of shattered chromosomes in Deinococcus radiodurans, Nature, vol.268, issue.7111, pp.569-573, 2006.
DOI : 10.1038/nature05160

URL : https://hal.archives-ouvertes.fr/hal-00195137

J. Zimmerman and R. Battista, A ring-like nucleoid is not necessary for radioresistance in the Deinococcaceae, BMC Microbiology, vol.5, issue.17, 2005.