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Recalage et fusion d'informations multimodales pour l'optimisation de la thérapie de resynchronisation cardiaque

Abstract : This work is based on the registration and the fusion of multi-modality data for cardiac resynchronization therapy (CRT) optimization. Local descriptors of the electro-mechanical coupling of the heart are extracted from anatomical, functional and mechanical data acquired from CT-scan volumes (CT), speckle tracking echocardiography (STE) and electro-anatomical mapping (EAM). The proposed approach is based on the registration of multi-modality data on a 3D+t model of the left ventricle (LV) computed from CT segmented surfaces. It consists in two steps : (1) the semi-interactive registration of EAM data and CT images ; (2) the registration of STE data on the dynamic model for which two automatic methods (one static, the other dynamic) have been developed. These step consider a radial based projection and an interpolation (radial basis function) of the electrical data on the proposed model as well as the synchronization and matching (by dynamic time warping) of temporal instants between the EAM and STE data. These methods allow the possibility to compute, under different cardiac stimulation modes, local activation times, voltage maps, mechanical delays and local electro-mechanical delays. The vizualisation (by 3D and 2D maps) of these descriptors gives the means to characterize the intra-segments electro-mechanical coupling of the LV. These methods have been applied on simulated and real data. They show the feasibility of extracting local descriptors of the cardiac function that are significant for the optimization of stimulation probes implantation in CRT.
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https://tel.archives-ouvertes.fr/tel-00756323
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Submitted on : Thursday, November 22, 2012 - 5:47:27 PM
Last modification on : Wednesday, September 14, 2022 - 10:20:04 AM
Long-term archiving on: : Saturday, February 23, 2013 - 3:46:18 AM

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  • HAL Id : tel-00756323, version 1

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François Tavard. Recalage et fusion d'informations multimodales pour l'optimisation de la thérapie de resynchronisation cardiaque. Traitement du signal et de l'image [eess.SP]. Université Rennes 1, 2012. Français. ⟨NNT : 2012REN1S043⟩. ⟨tel-00756323⟩

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