Skip to Main content Skip to Navigation
Theses

Etude de l'émission de particules chargées secondaires dans l'optique d'un monitorage faisceau et de la dosimétrie en ligne en hadronthérapie

Abstract : This work is devoted to the feasibility study of interaction vertex imaging (IVI) for real-time quality assurance in hadrontherapy treatments with carbon ion beams. Nuclear interaction vertex detection is based on secondary particle detection: a device allows us to spatially detect charged particles (tracker), thus we can reconstruct the trajectories of particles emerging from the patient and then extrapolate their emission point (vertex). In our study, the vertex position is determined by two ways: either by calculating the intersection of the trajectory of an emerging fragment with the trajectory of the incident ion (measured by means of a beam hodoscope upstream of the patient), or with the intersection of two emerging particles trajectories detected in coincidence. Our feasibility study of this technique relies on the GEANT4 simulation tool. The first part of the study aimed to validate this tool with experiments performed at GANIL (Caen) and GSI (Darmstadt) using carbon ion beams at various energies and in various targets (water or PMMA). Secondly, the comparison of two different technics for secondary particles detection showed that the technique using the hodoscope is the most efficient. Finally, after the parameters optimization of this technique, a realistic simulation shows that it is possible to measure ion paths within millimeter precision during each energy slices. A control of each beam spot may also be possible.
Complete list of metadata

Cited literature [70 references]  Display  Hide  Download

https://tel.archives-ouvertes.fr/tel-00712778
Contributor : Sylvie Flores <>
Submitted on : Thursday, June 28, 2012 - 10:05:00 AM
Last modification on : Friday, October 23, 2020 - 4:51:24 PM
Long-term archiving on: : Thursday, December 15, 2016 - 7:30:44 PM

Identifiers

  • HAL Id : tel-00712778, version 1

Collections

Citation

Pierre Henriquet. Etude de l'émission de particules chargées secondaires dans l'optique d'un monitorage faisceau et de la dosimétrie en ligne en hadronthérapie. Physique Médicale [physics.med-ph]. Université Claude Bernard - Lyon I, 2011. Français. ⟨tel-00712778⟩

Share

Metrics

Record views

1213

Files downloads

2146