Indexing of HSQC spectra and FMRI images for biomarker identification

Akram Belghith 1
1 Laboratoire des sciences de l'image, de l'informatique et de la télédétection (Strasbourg)
LSIIT / ICPS - Laboratoire de Sciences de l'Image, de l'Informatique et de la Télédétection, équipe ICPS
Abstract : The medical signal acquisition techniques are constantly evolving in recent years and providing an increasing amount of data which should be then analyzed. In this context, automatic signal processing methods are regularly proposed to assist the expert in the qualitative and quantitative analysis of these images in order to facilitate their interpretation. These methods should take into account the physics of signal acquisition, the a priori we have on the signal formation and the amount of data to analyze for a more accurate and reliable interpretation. In this thesis, we focus on the two-dimensional 2D Heteronuclear Single Quantum Coherence HSQC spectra obtained by High-Resolution Magic Angle Spinning HR-MAS NMR for biological tissue analysis and the functional Magnetic Resonance Imaging fMRI images for functional brain activities analysis. Each processed medical information will be characterized by a set of objects that we seek to extract, align, and code. The clustering of these objects by measuring their similarity will allow their classification and then the identification of biomarkers. It is this global content-based object indexing and retrieval scheme that we propose. We are interested in this thesis to properly model and integrate the a priori knowledge we have on these biological signal allowing us to propose thereafter appropriate methods to each indexing step and each type of signal.
Document type :
Theses
Other. Université de Strasbourg, 2012. English. <NNT : 2012STRAD001>


https://tel.archives-ouvertes.fr/tel-00712070
Contributor : Abes Star <>
Submitted on : Friday, July 6, 2012 - 11:37:47 AM
Last modification on : Wednesday, October 29, 2014 - 1:22:14 PM

File

Belghith_Akram_2012_ED269.pdf
fileSource_public_star

Identifiers

  • HAL Id : tel-00712070, version 1

Collections

Citation

Akram Belghith. Indexing of HSQC spectra and FMRI images for biomarker identification. Other. Université de Strasbourg, 2012. English. <NNT : 2012STRAD001>. <tel-00712070>

Export

Share

Metrics

Consultation de
la notice

355

Téléchargement du document

135