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The Dynamics of Mammalian P Body Transport, Assembly, and Disassembly In Vivo, Molecular Biology of the Cell, vol.19, issue.10, pp.4154-4166, 2008. ,
DOI : 10.1091/mbc.E08-05-0513
Clustering and conservation patterns of human microRNAs, Nucleic Acids Research, vol.33, issue.8, pp.2697-2706, 2005. ,
DOI : 10.1093/nar/gki567
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies, RNA, vol.11, issue.5, pp.717-727, 2005. ,
DOI : 10.1261/rna.2340405
In Vivo Kinetics of mRNA Splicing and Transport in Mammalian Cells, Molecular and Cellular Biology, vol.22, issue.19, pp.6706-6718, 2002. ,
DOI : 10.1128/MCB.22.19.6706-6718.2002
Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein, Genes Dev, vol.24, pp.904-915, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00788111
The impact of microRNAs on protein output, Nature, vol.35, issue.7209, pp.64-71, 2008. ,
DOI : 10.1038/nature07242
Control of developmental timing by small temporal RNAs: a paradigm for RNA-mediated regulation of gene expression, BioEssays, vol.286, issue.2, pp.119-129, 2002. ,
DOI : 10.1002/bies.10046
Northern blot normalization with a 28S rRNA olinucleotide probe, Nucleic Acids Research, vol.17, issue.17, p.7115, 1989. ,
DOI : 10.1093/nar/17.17.7115
MicroRNAs: Target Recognition and Regulatory Functions, Cell, vol.136, issue.2, pp.215-233, 2009. ,
DOI : 10.1016/j.cell.2009.01.002
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1, p.2, 2006. ,
Role for a bidentate ribonuclease in the initiation step of RNA interference, Nature, vol.409, issue.6818, pp.363-366, 2001. ,
DOI : 10.1038/35053110
AGO1 defines a novel locus of Arabidopsis controlling leaf development, The EMBO Journal, vol.17, issue.1, pp.170-180, 1998. ,
DOI : 10.1093/emboj/17.1.170
RNA polymerase III transcribes human microRNAs, Nature Structural & Molecular Biology, vol.13, issue.12, pp.1097-1101, 2006. ,
DOI : 10.1038/nsmb1167
RNA interference can target pre-mRNA: consequences for gene expression in a Caenorhabditis elegans operon, Genetics, vol.153, pp.1245-1256, 1999. ,
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila, Cell, vol.113, issue.1, pp.25-36, 2003. ,
DOI : 10.1016/S0092-8674(03)00231-9
Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing, RNA, vol.17, issue.10, pp.1858-1869, 2011. ,
DOI : 10.1261/rna.2778911
Widespread Translational Inhibition by Plant miRNAs and siRNAs, Science, vol.320, issue.5880, pp.1185-1190, 2008. ,
DOI : 10.1126/science.1159151
Revisiting the principles of microRNA target recognition and mode of action, Nature Reviews Molecular Cell Biology, vol.125, issue.2, pp.141-148, 2009. ,
DOI : 10.1038/nrm2619
URL : https://hal.archives-ouvertes.fr/hal-00370008
Tethering RITS to a Nascent Transcript Initiates RNAi- and Heterochromatin-Dependent Gene Silencing, Cell, vol.125, issue.5, pp.873-886, 2006. ,
DOI : 10.1016/j.cell.2006.04.025
URL : https://hal.archives-ouvertes.fr/inserm-00332367
Antisense RNA Stabilization Induces Transcriptional Gene Silencing via Histone Deacetylation in S. cerevisiae, Cell, vol.131, issue.4, pp.706-717, 2007. ,
DOI : 10.1016/j.cell.2007.09.014
Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells, Molecular Therapy, vol.12, issue.1, pp.179-183, 2005. ,
DOI : 10.1016/j.ymthe.2005.03.003
A micrococcal nuclease homologue in RNAi effector complexes, Nature, vol.425, issue.6956, pp.411-414, 2003. ,
DOI : 10.1038/nature01956
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells, Current Opinion in Cell Biology, vol.21, issue.3, pp.452-460, 2009. ,
DOI : 10.1016/j.ceb.2009.04.009
Ago???TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps, Nature Structural & Molecular Biology, vol.59, issue.11, pp.1160-1166, 2009. ,
DOI : 10.1093/emboj/17.12.3461
MicroRNA silencing through RISC recruitment of eIF6, Nature, vol.23, issue.7146, pp.823-828, 2007. ,
DOI : 10.1038/nature05841
Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter, Nucleic Acids Research, vol.38, issue.21, pp.7736-7748, 2010. ,
DOI : 10.1093/nar/gkq648
The Reality of Pervasive Transcription, PLoS Biology, vol.25, issue.7, p.1000625, 2011. ,
DOI : 10.1371/journal.pbio.1000625.s008
Cytoplasmic foci are sites of mRNA decay in human cells, The Journal of Cell Biology, vol.115, issue.1, pp.31-40, 2004. ,
DOI : 10.1016/S0962-8924(01)01982-1
Processing of primary microRNAs by the Microprocessor complex, Nature, vol.432, issue.7014, pp.231-235, 2004. ,
DOI : 10.1016/0014-4827(86)90560-4
The Developmental Timing Regulator AIN-1 Interacts with miRISCs and May Target the Argonaute Protein ALG-1 to Cytoplasmic P Bodies in C. elegans, Molecular Cell, vol.19, issue.4, pp.437-447, 2005. ,
DOI : 10.1016/j.molcel.2005.07.013
Antiviral Immunity Directed by Small RNAs, Cell, vol.130, issue.3, pp.413-426, 2007. ,
DOI : 10.1016/j.cell.2007.07.039
URL : https://hal.archives-ouvertes.fr/hal-00176625
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing, Genes & Development, vol.19, issue.19, pp.2301-2306, 2005. ,
DOI : 10.1101/gad.344205
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240039
A Parsimonious Model for Gene Regulation by miRNAs, Science, vol.331, issue.6017, 2011. ,
DOI : 10.1126/science.1191138
Specificity of microRNA target selection in translational repression, Genes & Development, vol.18, issue.5, 2004. ,
DOI : 10.1101/gad.1184404
Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components, Genes Dev, vol.21, pp.2539-2544, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00198842
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells, Nature, vol.411, issue.6836, pp.494-498, 2001. ,
DOI : 10.1038/35078107
P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing, Molecular and Cellular Biology, vol.27, issue.11, pp.3970-3981, 2007. ,
DOI : 10.1128/MCB.00128-07
GW182 interaction with Argonaute is essential for Bibliographie 183, 2008. ,
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing, Genes & Development, vol.21, issue.20, pp.2558-2570, 2007. ,
DOI : 10.1101/gad.443107
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing, Nucleic Acids Research, vol.37, issue.9, pp.2974-2983, 2009. ,
DOI : 10.1093/nar/gkp173
The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing, RNA, vol.15, issue.8, pp.1433-1442, 2009. ,
DOI : 10.1261/rna.1703809
A Phosphorylated Cytoplasmic Autoantigen, GW182, Associates with a Unique Population of Human mRNAs within Novel Cytoplasmic Speckles, Molecular Biology of the Cell, vol.13, issue.4, pp.1338-1351, 2002. ,
DOI : 10.1091/mbc.01-11-0544
The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and, 2003. ,
Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation, Molecular Cell, vol.35, issue.6, pp.868-880, 2009. ,
DOI : 10.1016/j.molcel.2009.08.004
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans, Nature, vol.391, issue.6669, pp.806-811, 1998. ,
DOI : 10.1038/35888
Chapter 23 Tethering Assays to Investigate Nonsense???Mediated mRNA Decay Activating Proteins, Methods Enzymol, vol.448, pp.467-482, 2008. ,
DOI : 10.1016/S0076-6879(08)02623-2
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity, Nature Cell Biology, vol.110, issue.9, pp.1143-1149, 2009. ,
DOI : 10.1016/S0168-9525(03)00140-9
URL : https://hal.archives-ouvertes.fr/hal-00423288
Viral Protein Inhibits RISC Activity by Argonaute Binding through Conserved WG/GW Motifs, PLoS Pathogens, vol.142, issue.7, p.1000996, 2010. ,
DOI : 10.1371/journal.ppat.1000996.s003
Accumulation of mature mRNA in the nuclear fraction of mammalian cells, FEBS Letters, vol.110, issue.3, pp.324-328, 1999. ,
DOI : 10.1016/S0014-5793(99)01175-8
The Microprocessor complex mediates the genesis of microRNAs, Nature, vol.12, issue.7014, pp.235-240, 2004. ,
DOI : 10.1038/nature03120
Transcription and RNA interference in the formation of heterochromatin, Nature, vol.282, issue.7143, pp.399-406, 2007. ,
DOI : 10.1038/nature05914
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways, Nature, vol.78, issue.7092, pp.537-541, 2006. ,
DOI : 10.1038/nature04791
Transcriptional silencing of a transgene by RNAi in the soma of C. elegans, Genes & Development, vol.19, issue.6, pp.683-696, 2005. ,
DOI : 10.1101/gad.1247705
Mammalian microRNAs predominantly act to decrease target mRNA levels, Nature, vol.5, issue.7308, pp.835-840, 2010. ,
DOI : 10.1038/nature09267
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing, EMBO reports, vol.3, issue.10, 2005. ,
DOI : 10.1038/9684
A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants, Science, vol.286, issue.5441, pp.950-952, 1999. ,
DOI : 10.1126/science.286.5441.950
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells, Nature, vol.404, pp.293-296, 2000. ,
Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi, Science, vol.293, issue.5532, pp.1146-1150, 2001. ,
DOI : 10.1126/science.1064023
Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells, Proceedings of the National Academy of Sciences, vol.104, issue.30, pp.12422-12427, 2007. ,
DOI : 10.1073/pnas.0701635104
A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon, EMBO J, vol.12, pp.3297-3304, 1993. ,
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells, Nucleic Acids Research, vol.37, issue.9, pp.2984-2995, 2009. ,
DOI : 10.1093/nar/gkp127
MicroRNAs: small RNAs with a big role in gene regulation, Nature Reviews Genetics, vol.1, issue.7, pp.522-531, 2004. ,
DOI : 10.1038/nature02363
A microRNA polycistron as a potential human oncogene, Nature, vol.435, pp.828-833, 2005. ,
Proteomic and functional analysis of Argonaute-containing mRNA???protein complexes in human cells, EMBO reports, vol.4, issue.11, pp.1052-1060, 2007. ,
DOI : 10.1126/science.1111444
Mitochondria Associate with P-bodies and Modulate MicroRNA-mediated RNA Interference, Journal of Biological Chemistry, vol.286, issue.27, pp.24219-24230, 2011. ,
DOI : 10.1074/jbc.M111.240259
Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing, The EMBO Journal, vol.11, issue.24, pp.4146-4160, 2010. ,
DOI : 10.1261/rna.1448009
siRNA-Mediated Heterochromatin Establishment Requires HP1 and Is Associated with Antisense Transcription, Molecular Cell, vol.31, issue.2, pp.178-189, 2008. ,
DOI : 10.1016/j.molcel.2008.07.003
Argonaute Slicing Is Required for Heterochromatic Silencing and Spreading, Science, vol.313, issue.5790, pp.1134-1137, 2006. ,
DOI : 10.1126/science.1128813
Involvement of AGO1 and AGO2 in mammalian transcriptional silencing, Nature Structural & Molecular Biology, vol.1, issue.9, pp.787-792, 2006. ,
DOI : 10.1038/nature02519
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs, Nature Chemical Biology, vol.60, issue.3, pp.166-173, 2007. ,
DOI : 10.1073/pnas.0607015103
RAS Is Regulated by the let-7 MicroRNA Family, Cell, vol.120, issue.5, pp.635-647, 2005. ,
DOI : 10.1016/j.cell.2005.01.014
MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS, Annual Review of Plant Biology, vol.57, issue.1, pp.19-53, 2006. ,
DOI : 10.1146/annurev.arplant.57.032905.105218
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells, Nature, vol.6, issue.7005, pp.211-217, 2004. ,
DOI : 10.1016/S0960-9822(02)00792-3
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling, The Journal of Cell Biology, vol.20, issue.6, pp.871-884, 2005. ,
DOI : 10.1242/jcs.01477
Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway, Cell, vol.95, issue.7, pp.1017-1026, 1998. ,
DOI : 10.1016/S0092-8674(00)81725-0
Functional siRNAs and miRNAs Exhibit Strand Bias, Cell, vol.115, issue.2, pp.209-216, 2003. ,
DOI : 10.1016/S0092-8674(03)00801-8
MicroRNA-directed transcriptional gene silencing in mammalian cells, Proceedings of the National Academy of Sciences, vol.105, issue.42, pp.16230-16235, 2008. ,
DOI : 10.1073/pnas.0808830105
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells, Nature Structural & Molecular Biology, vol.251, issue.9, pp.793-797, 2006. ,
DOI : 10.1016/j.cell.2006.01.036
Small RNAs: classification, biogenesis, and function, Mol Cells, vol.19, pp.1-15, 2005. ,
An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation, Cell, vol.129, issue.6, pp.1141-1151, 2007. ,
DOI : 10.1016/j.cell.2007.05.016
Listening to the silent genes: transgene silencing, gene regulation and pathogen control, Trends in Plant Science, vol.4, issue.9, pp.340-347, 1999. ,
DOI : 10.1016/S1360-1385(99)01467-3
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins, RNA, vol.15, issue.6, pp.1059-1066, 2009. ,
DOI : 10.1261/rna.1606309
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, Cell, vol.75, issue.5, pp.843-854, 1993. ,
DOI : 10.1016/0092-8674(93)90529-Y
URL : https://hal.archives-ouvertes.fr/in2p3-00597159
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules, Proceedings of the National Academy of Sciences, vol.103, issue.48, pp.18125-18130, 2006. ,
DOI : 10.1073/pnas.0608845103
Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2, Proceedings of the National Academy of Sciences, vol.75, issue.3, pp.1121-1125, 1978. ,
DOI : 10.1073/pnas.75.3.1121
Small dsRNAs induce transcriptional activation in human cells, Proceedings of the National Academy of Sciences, vol.103, issue.46, pp.17337-17342, 2006. ,
DOI : 10.1073/pnas.0607015103
Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing, Journal of Cell Science, vol.121, issue.24, pp.4134-4144, 2008. ,
DOI : 10.1242/jcs.036905
The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing, RNA, vol.15, issue.5, pp.804-813, 2009. ,
DOI : 10.1261/rna.1229409
Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3??? Trailers, PLoS ONE, vol.13, issue.5, p.10563, 2010. ,
DOI : 10.1371/journal.pone.0010563.s012
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs, Nature, vol.22, issue.7027, pp.769-773, 2005. ,
DOI : 10.1016/S0092-8674(00)00015-5
The role of RNA interference in heterochromatic silencing, Nature, vol.161, issue.7006, pp.364-370, 2004. ,
DOI : 10.1016/0092-8674(94)90119-8
Argonaute2 Is the Catalytic Engine of Mammalian RNAi, Science, vol.305, issue.5689, pp.1437-1441, 2004. ,
DOI : 10.1126/science.1102513
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies, Nature Cell Biology, vol.7, issue.7, pp.719-723, 2005. ,
DOI : 10.1261/rna.2340405
Nuclear Export of MicroRNA Precursors, Science, vol.303, issue.5654, pp.95-98, 2004. ,
DOI : 10.1126/science.1090599
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F, Science, vol.317, pp.1764-1767, 2007. ,
Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes, Cell, vol.123, issue.4, pp.607-620, 2005. ,
DOI : 10.1016/j.cell.2005.08.044
RNAi-mediated pathways in the nucleus, Nature Reviews Genetics, vol.269, issue.1, pp.24-35, 2005. ,
DOI : 10.1006/excr.1996.0186
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation, Science, vol.315, issue.5818, pp.1576-1579, 2007. ,
DOI : 10.1126/science.1137999
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs, Molecular Cell, vol.15, issue.2, pp.185-197, 2004. ,
DOI : 10.1016/j.molcel.2004.07.007
URL : http://doi.org/10.1016/j.molcel.2004.07.007
Transcriptional silencing and promoter methylation triggered by double-stranded RNA, The EMBO Journal, vol.101, issue.19, pp.5194-5201, 2000. ,
DOI : 10.1093/emboj/19.19.5194
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC302106
A direct role for Hsp90 in pre-RISC formation in Drosophila, Nature Structural & Molecular Biology, vol.15, issue.8, pp.1024-1026, 2010. ,
DOI : 10.1021/jm980403y
Small RNAs in transcriptional gene silencing and genome defence, Nature, vol.21, issue.7228, pp.413-420, 2009. ,
DOI : 10.1038/nature07756
Structure and activity of putative intronic miRNA promoters, RNA, vol.16, issue.3, pp.495-505, 2010. ,
DOI : 10.1261/rna.1731910
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans, Proceedings of the National Academy of Sciences, vol.95, issue.26, pp.15502-15507, 1998. ,
DOI : 10.1073/pnas.95.26.15502
Small Interfering RNA-Induced Transcriptional Gene Silencing in Human Cells, Science, vol.305, issue.5688, pp.1289-1292, 2004. ,
DOI : 10.1126/science.1101372
Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells, PLoS Genetics, vol.102, issue.11, p.1000258, 2008. ,
DOI : 10.1371/journal.pgen.1000258.s006
Two RNAi Complexes, RITS and RDRC, Physically Interact and Localize to Noncoding Centromeric RNAs, Cell, vol.119, issue.6, pp.789-802, 2004. ,
DOI : 10.1016/j.cell.2004.11.034
URL : https://hal.archives-ouvertes.fr/inserm-00332373
Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans, THE PLANT CELL ONLINE, vol.2, issue.4, pp.279-289, 1990. ,
DOI : 10.1105/tpc.2.4.279
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells, The EMBO Journal, vol.28, issue.12, pp.1708-1719, 2009. ,
DOI : 10.1073/pnas.0503853102
Synthesis and Modification of Nuclear Proteins in Serum-Stimulated 3T3 Cells, Biochemical Society Transactions, vol.5, issue.4, p.940, 1977. ,
DOI : 10.1042/bst0050940
A High-Resolution Structure of the Pre-microRNA Nuclear Export Machinery, Science, vol.326, issue.5957, pp.1275-1279, 2009. ,
DOI : 10.1126/science.1178705
miR-19 is a key oncogenic component of mir-17-92, Genes & Development, vol.23, issue.24, pp.2839-2849, 2009. ,
DOI : 10.1101/gad.1861409
The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation, Developmental Biology, vol.216, issue.2, pp.671-680, 1999. ,
DOI : 10.1006/dbio.1999.9523
MicroRNA-10a Binds the 5???UTR of Ribosomal Protein mRNAs and Enhances Their Translation, Molecular Cell, vol.30, issue.4, pp.460-471, 2008. ,
DOI : 10.1016/j.molcel.2008.05.001
Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies, Molecular Biology of the Cell, vol.20, issue.14, pp.3273-3284, 2009. ,
DOI : 10.1091/mbc.E09-01-0082
Argonaute: a scaffold for the function of short regulatory RNAs, Trends in Biochemical Sciences, vol.31, issue.11, pp.622-630, 2006. ,
DOI : 10.1016/j.tibs.2006.09.010
Conservation of the sequence and temporal expression of let-7, 2000. ,
CCR4-NOT Deadenylates mRNA Associated with RNA-Induced Silencing Complexes in Human Cells, Molecular and Cellular Biology, vol.30, issue.6, pp.1486-1494, 2010. ,
DOI : 10.1128/MCB.01481-09
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis, RNA, vol.10, issue.10, pp.1518-1525, 2004. ,
DOI : 10.1261/rna.7131604
MicroRNA-373 induces expression of genes with complementary promoter sequences, Proceedings of the National Academy of Sciences, vol.105, issue.5, pp.1608-1613, 2008. ,
DOI : 10.1073/pnas.0707594105
Defining Features and Exploring Chemical Modifications to Manipulate RNAa Activity, Current Pharmaceutical Biotechnology, vol.11, issue.5, pp.518-526, 2010. ,
DOI : 10.2174/138920110791591463
Small Interfering RNA Directed Reversal of Urokinase Plasminogen Activator Demethylation Inhibits Prostate Tumor Growth and Metastasis, Cancer Research, vol.67, issue.14, pp.6637-6646, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-0751
Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity, Proceedings of the National Academy of Sciences, vol.101, issue.40, pp.14385-14389, 2004. ,
DOI : 10.1073/pnas.0405913101
Purified Argonaute2 and an siRNA form recombinant human RISC, Nature Structural & Molecular Biology, vol.17, issue.4, pp.340-349, 2005. ,
DOI : 10.1107/S0907444994006396
Specific and potent RNAi in the nucleus of human cells, Nature Structural & Molecular Biology, vol.9, issue.2, pp.133-137, 2005. ,
DOI : 10.1038/nbt936
Genomic analysis of human microRNA transcripts, Proceedings of the National Academy of Sciences, vol.104, issue.45, pp.17719-17724, 2007. ,
DOI : 10.1073/pnas.0703890104
The Oligo(A) Tail on Histone mRNA Plays an Active Role in Translational Silencing of Histone mRNA during Xenopus Oogenesis, Molecular and Cellular Biology, vol.24, issue.6, pp.2513-2525, 2004. ,
DOI : 10.1128/MCB.24.6.2513-2525.2004
MicroRNAs in Development and Disease, Physiological Reviews, vol.91, issue.3, pp.827-887, 2011. ,
DOI : 10.1152/physrev.00006.2010
development, The Journal of Cell Biology, vol.104, issue.3, pp.349-358, 2006. ,
DOI : 10.1242/jcs.01477
URL : https://hal.archives-ouvertes.fr/halshs-01073909
The RNA-Induced Silencing Complex Is a Mg2+-Dependent Endonuclease, Current Biology, vol.14, issue.9, pp.787-791, 2004. ,
DOI : 10.1016/j.cub.2004.03.008
Widespread changes in protein synthesis induced by microRNAs, Nature, vol.4, issue.7209, pp.58-63, 2008. ,
DOI : 10.1038/nature07228
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies, Nature Cell Biology, vol.7, issue.6, pp.633-636, 2005. ,
DOI : 10.1016/j.cell.2004.12.038
mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage, Differentiation, vol.73, issue.6, pp.287-293, 2005. ,
DOI : 10.1111/j.1432-0436.2005.00029.x
GW body disassembly triggered by siRNAs independently of their silencing activity, Nucleic Acids Research, vol.35, issue.14, pp.4715-4727, 2007. ,
DOI : 10.1093/nar/gkm491
The Coming of Age for Piwi Proteins, Molecular Cell, vol.26, issue.5, pp.603-609, 2007. ,
DOI : 10.1016/j.molcel.2007.05.021
Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies, Science, vol.300, issue.5620, pp.805-808, 2003. ,
DOI : 10.1126/science.1082320
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity, Science, vol.305, issue.5689, pp.1434-1437, 2004. ,
DOI : 10.1126/science.1102514
Unravelling the ultrastructure of Bibliographie 191, 2009. ,
Mammalian hyperplastic discs Homolog EDD Regulates miRNA-Mediated Gene Silencing, Molecular Cell, vol.43, issue.1, pp.97-109, 2011. ,
DOI : 10.1016/j.molcel.2011.06.013
URL : http://doi.org/10.1016/j.molcel.2011.06.013
GERp95 Belongs to a Family of Signal-transducing Proteins and Requires Hsp90 Activity for Stability and Golgi Localization, Journal of Biological Chemistry, vol.276, issue.46, pp.43294-43299, 2001. ,
DOI : 10.1074/jbc.M107808200
Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer, EMBO reports, vol.5, issue.2, pp.189-194, 2004. ,
DOI : 10.1038/sj.embor.7400070
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation, Nature, vol.280, issue.7216, pp.1124-1128, 2008. ,
DOI : 10.1038/nature07299
A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain, Nature Structural & Molecular Biology, vol.74, issue.10, pp.897-903, 2007. ,
DOI : 10.1038/nsmb1302
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation, Nature Genetics, vol.89, issue.8, pp.906-910, 2005. ,
DOI : 10.1038/ng1611
Gene expression: Long-term gene silencing by RNAi, Nature, vol.441, issue.7105, p.882, 2006. ,
DOI : 10.1038/442882a
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2, Cell, vol.128, issue.6, pp.1105-1118, 2007. ,
DOI : 10.1016/j.cell.2007.01.038
Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation, Science, vol.318, issue.5858, pp.1931-1934, 2007. ,
DOI : 10.1126/science.1149460
Post-transcriptional gene silencing in plants, J Cell Sci, vol.114, pp.3083-3091, 2001. ,
URL : https://hal.archives-ouvertes.fr/hal-01001529
Transcriptional gene silencing in plants: targets, inducers and regulators, Trends in Genetics, vol.17, issue.1, pp.29-35, 2001. ,
DOI : 10.1016/S0168-9525(00)02166-1
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi, Science, vol.297, issue.5588, pp.1833-1837, 2002. ,
DOI : 10.1126/science.1074973
An Unconventional Human Ccr4-Caf1 Deadenylase Complex in Nuclear Cajal Bodies, Molecular and Cellular Biology, vol.27, issue.5, pp.1686-1695, 2007. ,
DOI : 10.1128/MCB.01483-06
Recapitulation of Short RNA-Directed Translational Gene Silencing In Vitro, Molecular Cell, vol.22, issue.4, pp.553-560, 2006. ,
DOI : 10.1016/j.molcel.2006.03.034
RNA-directed de novo methylation of genomic sequences in plants, Cell, vol.76, issue.3, pp.567-576, 1994. ,
DOI : 10.1016/0092-8674(94)90119-8
A model for RNA-mediated gene silencing in higher plants, Plant Molecular Biology, vol.37, issue.2, pp.349-362, 1998. ,
DOI : 10.1023/A:1005946720438
Mature mRNAs accumulated in the nucleus are neither the molecules in transit to the cytoplasm nor constitute a stockpile for gene expression, RNA, vol.6, issue.7, pp.962-975, 2000. ,
DOI : 10.1017/S1355838200000479
RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2., Molecular and Cellular Biology, vol.10, issue.11, pp.5865-5875, 1990. ,
DOI : 10.1128/MCB.10.11.5865
An RNA targeted to the HIV-1 LTR promoter modulates indiscriminate off-target gene activation, Nucleic Acids Research, vol.35, issue.21, pp.7303-7312, 2007. ,
DOI : 10.1093/nar/gkm847
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells, RNA, vol.12, issue.2, pp.256-262, 2006. ,
DOI : 10.1261/rna.2235106
Specific interference with gene function by double-stranded RNA in early mouse development, Nature Cell Biology, vol.126, issue.2, pp.70-75, 2000. ,
DOI : 10.1101/GAD.13.22.3015
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development., Genes & Development, vol.5, issue.10, pp.1813-1824, 1991. ,
DOI : 10.1101/gad.5.10.1813
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans, Cell, vol.75, issue.5, pp.855-862, 1993. ,
DOI : 10.1016/0092-8674(93)90530-4
MicroRNAs direct rapid deadenylation of mRNA, Proceedings of the National Academy of Sciences, vol.103, issue.11, pp.4034-4039, 2006. ,
DOI : 10.1073/pnas.0510928103
Specific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells, Molecular and Cellular Biology, vol.21, issue.22, pp.7807-7816, 2001. ,
DOI : 10.1128/MCB.21.22.7807-7816.2001
Divergent GW182 functional domains in the regulation of translational silencing, Nucleic Acids Research, vol.39, issue.7, pp.2534-2547, 2011. ,
DOI : 10.1093/nar/gkq1099
MicroRNA-Directed Cleavage of HOXB8 mRNA, Science, vol.304, issue.5670, pp.594-596, 2004. ,
DOI : 10.1126/science.1097434
MicroRNAs in the Hox network: an apparent link to posterior prevalence, Nature Reviews Genetics, vol.5, issue.10, pp.789-796, 2008. ,
DOI : 10.1038/nrg2400
MicroRNAs and their roles in mammalian stem cells, Journal of Cell Science, vol.124, issue.11, pp.1775-1783, 2011. ,
DOI : 10.1242/jcs.069104
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs, Genes & Development, vol.17, issue.24, pp.3011-3016, 2003. ,
DOI : 10.1101/gad.1158803
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA, Nature, vol.290, issue.7175, pp.202-206, 2008. ,
DOI : 10.1038/nature06468
The Silencing Domain of GW182 Interacts with PABPC1 To Promote Translational Repression and Degradation of MicroRNA Targets and Is Required for Target Release, Molecular and Cellular Biology, vol.29, issue.23, pp.6220-6231, 2009. ,
DOI : 10.1128/MCB.01081-09
Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies, Biochemical Journal, vol.413, issue.3, pp.429-436, 2008. ,
DOI : 10.1042/BJ20080599
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression, RNA, vol.15, issue.5, pp.781-793, 2009. ,
DOI : 10.1261/rna.1448009