D. Charnock-jones, P. Kaufmann, and T. Mayhew, Aspects of Human Fetoplacental Vasculogenesis and Angiogenesis. I. Molecular Regulation, Placenta, vol.25, issue.2-3, pp.103-116, 2004.
DOI : 10.1016/j.placenta.2003.10.004

E. Jauniaux, A. Watson, J. Hempstock, Y. Bao, J. Skepper et al., Onset of Maternal Arterial Blood Flow and Placental Oxidative Stress, The American Journal of Pathology, vol.157, issue.6, pp.2111-2133, 2000.
DOI : 10.1016/S0002-9440(10)64849-3

I. Caniggia, J. Winter, S. Lye, and M. Post, Oxygen and Placental Development During the First Trimester: Implications for the Pathophysiology of Pre-eclampsia, Placenta, vol.21, pp.25-30, 2000.
DOI : 10.1053/plac.1999.0522

B. Sibai, G. Dekker, and M. Kupferminc, Pre-eclampsia, The Lancet, vol.365, issue.9461, pp.785-99, 2005.
DOI : 10.1016/S0140-6736(05)71003-5

G. Neufeld, T. Cohen, S. Gengrinovitch, and Z. Poltorak, Vascular endothelial growth factor (VEGF) and its receptors, Faseb J, vol.13, pp.9-22, 1999.

G. Yancopoulos, M. Klagsbrun, and J. Folkman, Vasculogenesis, Angiogenesis, and Growth Factors: Ephrins Enter the Fray at the Border, Cell, vol.93, issue.5, pp.661-665, 1998.
DOI : 10.1016/S0092-8674(00)81426-9

S. Smith, Angiogenesis and implantation, Hum Reprod, vol.15, issue.6, pp.59-66, 2000.

D. Charnock-jones, A. Sharkey, C. Boocock, A. Ahmed, R. Plevin et al., Vascular Endothelial Growth Factor Receptor Localization and Activation in Human Trophoblast and Choriocarcinoma Cells1, Biology of Reproduction, vol.51, issue.3, pp.524-554, 1994.
DOI : 10.1095/biolreprod51.3.524

A. Athanassiades and P. Lala, Role of placenta prowth factor (PIGF) in human extravillous trophoblast proliferation, migration and invasiveness, Placenta, vol.19, issue.7, pp.465-73, 1998.
DOI : 10.1016/S0143-4004(98)91039-6

R. Levine, S. Maynard, C. Qian, K. Lim, L. England et al., Circulating Angiogenic Factors and the Risk of Preeclampsia, New England Journal of Medicine, vol.350, issue.7, pp.672-83, 2004.
DOI : 10.1056/NEJMoa031884

R. Taylor, J. Grimwood, R. Taylor, M. Mcmaster, S. Fisher et al., Longitudinal serum concentrations of placental growth factor: Evidence for abnormal placental angiogenesis in pathologic pregnancies, American Journal of Obstetrics and Gynecology, vol.188, issue.1, pp.177-82, 2003.
DOI : 10.1067/mob.2003.111

Y. Zhou, M. Mcmaster, K. Woo, M. Janatpour, J. Perry et al., Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome, The American Journal of Pathology, vol.160, issue.4, pp.1405-1428, 2002.
DOI : 10.1016/S0002-9440(10)62567-9

M. Ziche, D. Maglione, D. Ribatti, L. Morbidelli, C. Lago et al., Persico MG 1997 Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic, Lab Invest, vol.76, pp.517-548

M. Dellian, B. Witwer, H. Salehi, F. Yuan, and R. Jain, Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment, Am J Pathol, vol.149, pp.59-71, 1996.

G. Palade, M. Simionescu, and N. Simionescu, Structural aspects of the permeability of the microvascular endothelium, Acta Physiol Scand, vol.463, pp.11-32, 1979.

W. Roberts, J. Delaat, M. Nagane, S. Huang, W. Cavenee et al., Host Microvasculature Influence on Tumor Vascular Morphology and Endothelial Gene Expression, The American Journal of Pathology, vol.153, issue.4, pp.1239-1287, 1998.
DOI : 10.1016/S0002-9440(10)65668-4

P. Stewart and M. Wiley, Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras, Developmental Biology, vol.84, issue.1, pp.183-92, 1981.
DOI : 10.1016/0012-1606(81)90382-1

J. Lecouter, J. Kowalski, J. Foster, P. Hass, Z. Zhang et al., Identification of an Angiogenic Mitogen Selective for Endocrine Gland Endothelium, Obstetrical and Gynecological Survey, vol.57, issue.1, pp.877-84, 2001.
DOI : 10.1097/00006254-200201000-00018

J. Lecouter, R. Lin, and N. Ferrara, Endocrine gland???derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis, Nature Medicine, vol.127, issue.9, pp.913-920, 2002.
DOI : 10.1038/417405a

J. Lecouter, R. Lin, M. Tejada, G. Frantz, F. Peale et al., The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells, Proceedings of the National Academy of Sciences, vol.100, issue.5, pp.2685-90, 2003.
DOI : 10.1073/pnas.0337667100

D. Lin, C. Bullock, F. Ehlert, J. Chen, H. Tian et al., Identification and Molecular Characterization of Two Closely Related G Protein-coupled Receptors Activated by Prokineticins/Endocrine Gland Vascular Endothelial Growth Factor, Journal of Biological Chemistry, vol.277, issue.22, pp.19276-80, 2002.
DOI : 10.1074/jbc.M202139200

H. Kliman, J. Nestler, E. Sermasi, J. Sanger, and J. Strauss, Differentiation of Cytotrophoblasts from Human Term Placentae*, Endocrinology, vol.118, issue.4, pp.1567-82, 1986.
DOI : 10.1210/endo-118-4-1567

A. Tarrade, L. Kuen, R. Malassine, A. Tricottet, V. Blain et al., Characterization of Human Villous and Extravillous Trophoblasts Isolated from First Trimester Placenta, Laboratory Investigation, vol.81, issue.9, pp.1199-211
DOI : 10.1038/labinvest.3780334

E. Alsat, V. Mirlesse, C. Fondacci, and M. Dodeur, Parathyroid Hormone Increases Epidermal Growth Factor Receptors in Cultured Human Trophoblastic Cells from Early and Term Placenta, The Journal of Clinical Endocrinology & Metabolism, vol.73, issue.2, pp.288-95
DOI : 10.1210/jcem-73-2-288

D. Torry, M. Hinrichs, and R. Torry, Determinants of Placental Vascularity, American Journal of Reproductive Immunology, vol.122, issue.4, pp.257-68, 2004.
DOI : 10.1093/emboj/18.4.934

A. Kaser, M. Winklmayr, G. Lepperdinger, and G. Kreil, The AVIT protein family: Secreted cysteine-rich vertebrate proteins with diverse functions, EMBO reports, vol.4, issue.5, pp.469-73, 2003.
DOI : 10.1038/sj.embor.embor830

J. Chung, Y. Song, Y. Wang, R. Magness, and J. Zheng, Differential Expression of Vascular Endothelial Growth Factor (VEGF), Endocrine Gland Derived-VEGF, and VEGF Receptors in Human Placentas from Normal and Preeclamptic Pregnancies, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.5, pp.2484-90, 2004.
DOI : 10.1210/jc.2003-031580

S. Battersby, H. Critchley, K. Morgan, R. Millar, and H. Jabbour, Expression and Regulation of the Prokineticins (Endocrine Gland-Derived Vascular Endothelial Growth Factor and Bv8) and Their Receptors in the Human Endometrium across the Menstrual Cycle, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.5, pp.2463-2472, 2004.
DOI : 10.1210/jc.2003-032012

C. Wulff, M. Weigand, R. Kreienberg, and H. Fraser, Angiogenesis during primate placentation in health and disease, Reproduction, vol.126, issue.5, pp.569-77, 2003.
DOI : 10.1530/rep.0.1260569

C. Wulff, H. Wilson, S. Dickson, S. Wiegand, and H. Fraser, Hemochorial Placentation in the Primate: Expression of Vascular Endothelial Growth Factor, Angiopoietins, and Their Receptors Throughout Pregnancy1, Biology of Reproduction, vol.66, issue.3, pp.802-814, 2002.
DOI : 10.1095/biolreprod66.3.802

R. Lin, J. Lecouter, J. Kowalski, and N. Ferrara, Characterization of Endocrine Gland-derived Vascular Endothelial Growth Factor Signaling in Adrenal Cortex Capillary Endothelial Cells, Journal of Biological Chemistry, vol.277, issue.10, pp.8724-8733, 2002.
DOI : 10.1074/jbc.M110594200

Y. Masuda, Y. Takatsu, Y. Terao, S. Kumano, Y. Ishibashi et al., Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors, Biochemical and Biophysical Research Communications, vol.293, issue.1, pp.396-402, 2002.
DOI : 10.1016/S0006-291X(02)00239-5

T. Soga, S. Matsumoto, T. Oda, T. Saito, H. Hiyama et al., Molecular cloning and characterization of prokineticin receptors, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1579, issue.2-3, pp.173-182, 2002.
DOI : 10.1016/S0167-4781(02)00546-8

T. Kisliouk, N. Levy, A. Hurwitz, and R. Meidan, Presence and Regulation of Endocrine Gland Vascular Endothelial Growth Factor/Prokineticin-1 and Its Receptors in Ovarian Cells, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.8, pp.3700-3707, 2003.
DOI : 10.1210/jc.2003-030492

A. Ahmed, C. Dunk, S. Ahmad, and A. Khaliq, Regulation of Placental Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PlGF) and Soluble Flt-1 by Oxygen??? A Review, Placenta, vol.21, pp.16-24, 2000.
DOI : 10.1053/plac.1999.0524

J. Kingdom and P. Kaufmann, Oxygen and Placental Vascular Development, Adv Exp Med Biol, vol.474, pp.259-75, 1999.
DOI : 10.1007/978-1-4615-4711-2_20

L. Schaffer, A. Scheid, P. Spielmann, C. Breymann, R. Zimmermann et al., Oxygen-regulated Expression of TGF-??3, a Growth Factor Involved in Trophoblast Differentiation, Placenta, vol.24, issue.10, pp.941-50, 2003.
DOI : 10.1016/S0143-4004(03)00166-8

H. Li, B. Gu, Y. Zhang, D. Lewis, and Y. Wang, Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta, Placenta, vol.26, issue.2-3, pp.210-217, 2005.
DOI : 10.1016/j.placenta.2004.05.004

T. Nagamatsu, T. Fujii, M. Kusumi, L. Zou, T. Yamashita et al., Cytotrophoblasts Up-Regulate Soluble Fms-Like Tyrosine Kinase-1 Expression under Reduced Oxygen: An Implication for the Placental Vascular Development and the Pathophysiology of Preeclampsia, Endocrinology, vol.145, issue.11, pp.4838-4883, 2004.
DOI : 10.1210/en.2004-0533

G. J. Burton and E. Jauniaux, Placental oxidative stress: From miscarriage to preeclampsia, Journal of the Society for Gynecologic Investigation, vol.11, issue.6, pp.342-52, 2004.
DOI : 10.1016/j.jsgi.2004.03.003

V. Chaddha, Developmental biology of the placenta and the origins of placental insufficiency, Seminars in Fetal and Neonatal Medicine, vol.9, issue.5, pp.357-69, 2004.
DOI : 10.1016/j.siny.2004.03.006

G. Neufeld, Vascular endothelial growth factor (VEGF) and its receptors, Faseb J, vol.13, issue.1, pp.9-22, 1999.

W. Risau, Mechanisms of angiogenesis, Nature, vol.386, issue.6626, pp.671-675, 1997.

G. D. Yancopoulos, M. Klagsbrun, and J. Folkman, Vasculogenesis, Angiogenesis, and Growth Factors: Ephrins Enter the Fray at the Border, Cell, vol.93, issue.5, pp.93-661, 1998.
DOI : 10.1016/S0092-8674(00)81426-9

R. J. Levine, Circulating Angiogenic Factors and the Risk of Preeclampsia, New England Journal of Medicine, vol.350, issue.7, pp.672-83, 2004.
DOI : 10.1056/NEJMoa031884

R. N. Taylor, Longitudinal serum concentrations of placental growth factor: Evidence for abnormal placental angiogenesis in pathologic pregnancies, American Journal of Obstetrics and Gynecology, vol.188, issue.1, pp.177-82, 2003.
DOI : 10.1067/mob.2003.111

Y. Zhou, Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome, The American Journal of Pathology, vol.160, issue.4, pp.1405-1428, 2002.
DOI : 10.1016/S0002-9440(10)62567-9

M. Ziche, Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic, Lab Invest, vol.76, issue.4, pp.517-548, 1997.

J. Lecouter, Identification of an Angiogenic Mitogen Selective for Endocrine Gland Endothelium, Obstetrical and Gynecological Survey, vol.57, issue.1, pp.412-877, 2001.
DOI : 10.1097/00006254-200201000-00018

J. Lecouter, R. Lin, and N. Ferrara, Endocrine gland???derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis, Nature Medicine, vol.127, issue.9, pp.913-920, 2002.
DOI : 10.1038/417405a

J. Lecouter, The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells, Proceedings of the National Academy of Sciences, vol.100, issue.5, pp.2685-90, 2003.
DOI : 10.1073/pnas.0337667100

P. Hoffmann, J. J. Feige, and N. Alfaidy, Expression and Oxygen Regulation of Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 and Its Receptors in Human Placenta during Early Pregnancy, Endocrinology, vol.147, issue.4, pp.1675-84, 2006.
DOI : 10.1210/en.2005-0912
URL : https://hal.archives-ouvertes.fr/inserm-00375826

P. Georgiades, A. C. Ferguson-smith, and G. J. Burton, Comparative Developmental Anatomy of the Murine and Human Definitive Placentae, Placenta, vol.23, issue.1, pp.3-19, 2002.
DOI : 10.1053/plac.2001.0738

A. Malassine, J. L. Frendo, and D. , Evain-Brion, A comparison of placental development and endocrine functions between the human and mouse model, Hum Reprod Update, issue.96, pp.531-540, 2003.

J. Rossant and J. C. Cross, PLACENTAL DEVELOPMENT: LESSONS FROM MOUSE MUTANTS, Nature Reviews Genetics, vol.2, issue.7, pp.538-586, 2001.
DOI : 10.1038/35080570

N. Alfaidy, Oxygen Regulation of Placental 11??-Hydroxysteroid Dehydrogenase 2: Physiological and Pathological Implications, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.10, pp.4797-805, 2002.
DOI : 10.1210/jc.2002-020310

R. H. Adams and G. A. Wilkinson, Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis, Genes & Development, vol.13, issue.3, pp.295-306, 1999.
DOI : 10.1101/gad.13.3.295

R. Agrawal and H. Jacobs, Concentration of vascular endothelial growth factor released by cultured human luteinized granulosa cells is higher in women with polycystic ovaries than in women with normal ovaries, Fertility and Sterility, vol.78, issue.6, pp.1164-1173, 2002.
DOI : 10.1016/S0015-0282(02)04242-5

S. Ahmad and A. Ahmed, Antiangiogenic Effect of Soluble Vascular Endothelial Growth Factor Receptor-1 in Placental Angiogenesis, Endothelium, vol.8, issue.1-2, pp.89-95, 2005.
DOI : 10.1016/S0029-7844(99)00565-7

A. Ahmed and C. Dunk, Regulation of Placental Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PlGF) and Soluble Flt-1 by Oxygen??? A Review, Placenta, vol.21, pp.16-24, 2000.
DOI : 10.1053/plac.1999.0524

N. Alfaidy and S. Gupta, Oxygen Regulation of Placental 11??-Hydroxysteroid Dehydrogenase 2: Physiological and Pathological Implications, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.10, pp.4797-805, 2002.
DOI : 10.1210/jc.2002-020310

N. Alfaidy and W. Li, Late Gestation Increase in 11??-Hydroxysteroid Dehydrogenase 1 Expression in Human Fetal Membranes: A Novel Intrauterine Source of Cortisol, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.10, pp.5033-5041, 2003.
DOI : 10.1210/jc.2002-021915

E. Alsat and V. Mirlesse, Parathyroid Hormone Increases Epidermal Growth Factor Receptors in Cultured Human Trophoblastic Cells from Early and Term Placenta, The Journal of Clinical Endocrinology & Metabolism, vol.73, issue.2, pp.288-95, 1991.
DOI : 10.1210/jcem-73-2-288

J. D. Aplin, Molecular and Cellular Aspects of Peri-implantation Processes, Placenta, vol.15, issue.161, pp.109-120, 1994.

A. Athanassiades and G. S. Hamilton, Vascular Endothelial Growth Factor Stimulates Proliferation but Not Migration or Invasiveness in Human Extravillous Trophoblast1, Biology of Reproduction, vol.59, issue.3, pp.643-54, 1998.
DOI : 10.1095/biolreprod59.3.643

A. Athanassiades and P. K. Lala, Role of placenta prowth factor (PIGF) in human extravillous trophoblast proliferation, migration and invasiveness, Placenta, vol.19, issue.7, pp.465-73, 1998.
DOI : 10.1016/S0143-4004(98)91039-6

M. Autiero and J. Waltenberger, Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1, Nature Medicine, vol.9, issue.7, pp.936-979, 2003.
DOI : 10.1038/nm884

J. S. Babischkin and D. L. Suresch, Differential Expression of Placental Villous Angiopoietin-1 and -2 During Early, Mid and Late Baboon Pregnancy, Placenta, vol.28, issue.2-3, 2006.
DOI : 10.1016/j.placenta.2006.02.003

S. Battersby and H. O. Critchley, Expression and Regulation of the Prokineticins (Endocrine Gland-Derived Vascular Endothelial Growth Factor and Bv8) and Their Receptors in the Human Endometrium across the Menstrual Cycle, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.5, pp.2463-2472, 2004.
DOI : 10.1210/jc.2003-032012

M. Ben-zimra and M. Koler, Uterine and placental expression of steroidogenic genes during rodent pregnancy, Molecular and Cellular Endocrinology, vol.187, issue.1-2, pp.223-254, 2002.
DOI : 10.1016/S0303-7207(01)00713-4

E. Berra and A. Ginouves, The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling, EMBO reports, vol.56, issue.1, pp.41-46, 2006.
DOI : 10.1074/jbc.M211058200
URL : https://hal.archives-ouvertes.fr/hal-00321549

J. Boisbouvier and J. P. Albrand, A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis, Journal of Molecular Biology, vol.283, issue.1, pp.205-224, 1998.
DOI : 10.1006/jmbi.1998.2057

T. D. Burrows and A. King, Expression of adhesion molecules by endovascular trophoblast and decidual endothelial cells: Implications for vascular invasion during implantation, Placenta, vol.15, issue.1, pp.21-33, 1994.
DOI : 10.1016/S0143-4004(05)80233-4

G. J. Burton and E. Jauniaux, Placental oxidative stress: From miscarriage to preeclampsia, Journal of the Society for Gynecologic Investigation, vol.11, issue.6, pp.342-52, 2004.
DOI : 10.1016/j.jsgi.2004.03.003

G. J. Burton and E. Jauniaux, Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: The Boyd Collection revisited, American Journal of Obstetrics and Gynecology, vol.181, issue.3, pp.718-742, 1999.
DOI : 10.1016/S0002-9378(99)70518-1

G. J. Burton and J. N. Skepper, A Reappraisal of the Contrasting Morphological Appearances of Villous Cytotrophoblast Cells During Early Human Pregnancy; Evidence for Both Apoptosis and Primary Necrosis, Placenta, vol.24, issue.4, pp.297-305, 2003.
DOI : 10.1053/plac.2002.0882

I. Caniggia and S. Grisaru-gravnosky, Inhibition of TGF-??3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies, Journal of Clinical Investigation, vol.103, issue.12, pp.1641-50, 1999.
DOI : 10.1172/JCI6380

I. Caniggia and H. Mostachfi, Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGF??3, Journal of Clinical Investigation, vol.105, issue.5, pp.577-87, 2000.
DOI : 10.1172/JCI8316

I. Caniggia and J. Winter, Oxygen and Placental Development During the First Trimester: Implications for the Pathophysiology of Pre-eclampsia, Placenta, vol.21, pp.25-30, 2000.
DOI : 10.1053/plac.1999.0522

L. Carbillon and M. Uzan, Prospective Evaluation of Uterine Artery Flow Velocity Waveforms at 12???14 and 22???24 Weeks of Gestation in Relation to Pregnancy Outcome and Birth Weight, Fetal Diagnosis and Therapy, vol.19, issue.4, pp.381-385, 2004.
DOI : 10.1159/000077971

M. Castellucci and G. Kosanke, Villous sprouting: fundamental mechanisms of human placental development, Human Reproduction Update, vol.6, issue.5, pp.485-94, 2000.
DOI : 10.1093/humupd/6.5.485

V. Chaddha and S. Viero, Developmental biology of the placenta and the origins of placental insufficiency, Seminars in Fetal and Neonatal Medicine, vol.9, issue.5, pp.357-69, 2004.
DOI : 10.1016/j.siny.2004.03.006

J. C. Challier and S. Uzan, Le placenta humain et ses pathologies : l???oxyg??ne en question, m??decine/sciences, vol.19, issue.11, pp.1111-1131, 2003.
DOI : 10.1051/medsci/200319111111
URL : http://www.erudit.org/revue/ms/2003/v19/n11/007284ar.pdf

D. S. Charnock-jones and P. Kaufmann, Aspects of Human Fetoplacental Vasculogenesis and Angiogenesis. I. Molecular Regulation, Placenta, vol.25, issue.2-3, pp.103-116, 2004.
DOI : 10.1016/j.placenta.2003.10.004

D. S. Charnock-jones and A. M. Sharkey, Vascular Endothelial Growth Factor Receptor Localization and Activation in Human Trophoblast and Choriocarcinoma Cells1, Biology of Reproduction, vol.51, issue.3, pp.524-554, 1994.
DOI : 10.1095/biolreprod51.3.524

M. Y. Cheng and C. M. Bullock, Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus, Nature, vol.417, issue.6887, pp.405-415, 2002.
DOI : 10.1038/417405a

M. Y. Cheng and F. M. Leslie, Expression of prokineticins and their receptors in the adult mouse brain, The Journal of Comparative Neurology, vol.132, issue.6, pp.796-809, 2006.
DOI : 10.1002/cne.21087

C. S. Chennakesava and S. D. Santo, Differential Expression of the Receptor Tyrosine Kinase EphB4 and Its Ligand Ephrin-B2 During Human Placental Development, Placenta, vol.27, issue.9-10, pp.9-10, 2006.
DOI : 10.1016/j.placenta.2005.10.008

J. Y. Chung and Y. Song, Differential Expression of Vascular Endothelial Growth Factor (VEGF), Endocrine Gland Derived-VEGF, and VEGF Receptors in Human Placentas from Normal and Preeclamptic Pregnancies, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.5, pp.2484-90, 2004.
DOI : 10.1210/jc.2003-031580

D. E. Clark and S. K. Smith, A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1, Biology of Reproduction, vol.59, issue.6, pp.1540-1548, 1998.
DOI : 10.1095/biolreprod59.6.1540

G. Collo and M. S. Pepper, Endothelial cell integrin alpha5beta1 expression is modulated by cytokines and during migration in vitro, J Cell Sci, vol.112, pp.569-78, 1999.

M. Coppens and P. Loquet, Longitudinal evaluation of uteroplacental and umbilical blood flow changes in normal early pregnancy, Ultrasound in Obstetrics and Gynecology, vol.7, issue.2, pp.114-135, 1996.
DOI : 10.1046/j.1469-0705.1996.07020114.x

C. H. Damsky and M. L. Fitzgerald, Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo., Journal of Clinical Investigation, vol.89, issue.1, pp.210-232, 1992.
DOI : 10.1172/JCI115565

R. L. Davisson and D. S. Hoffmann, Discovery of a Spontaneous Genetic Mouse Model of Preeclampsia, Hypertension, vol.39, issue.2, pp.337-379, 2002.
DOI : 10.1161/hy02t2.102904

D. Wolf, F. , and W. B. Robertson, The ultrastructure of acute atherosis in hypertensive pregnancy, American Journal of Obstetrics and Gynecology, vol.123, issue.2, pp.164-74, 1975.
DOI : 10.1016/0002-9378(75)90522-0

G. A. Dekker and B. M. Sibai, Etiology and Pathogenesis of Preeclampsia, Obstetric Anesthesia Digest, vol.19, issue.1, pp.1359-75, 1998.
DOI : 10.1097/00132582-199903000-00010

M. Dellian and B. P. Witwer, Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment, Am J Pathol, vol.149, issue.1, pp.59-71, 1996.

R. Demir and U. A. Kayisli, Sequential Expression of VEGF and its Receptors in Human Placental Villi During Very Early Pregnancy: Differences Between Placental Vasculogenesis and Angiogenesis, Placenta, vol.25, issue.6, pp.560-72, 2004.
DOI : 10.1016/j.placenta.2003.11.011

A. Dokras and D. S. Hoffmann, Severe Feto-Placental Abnormalities Precede the Onset of Hypertension and Proteinuria in a Mouse Model of Preeclampsia, Biol Reprod, 2006.

F. Dominguez and M. Yanez-mo, Embryonic implantation and leukocyte transendothelial migration: different processes with similar players?, The FASEB Journal, vol.19, issue.9, pp.1056-60, 2005.
DOI : 10.1096/fj.05-3781hyp

M. Dorsch and Y. Qiu, PK1/EG-VEGF induces monocyte differentiation and activation, Journal of Leukocyte Biology, vol.78, issue.2, pp.426-460, 2005.
DOI : 10.1189/jlb.0205061

C. Dunk and M. Shams, Angiopoietin-1 and Angiopoietin-2 Activate Trophoblast Tie-2 to Promote Growth and Migration during Placental Development, The American Journal of Pathology, vol.156, issue.6, pp.2185-99, 2000.
DOI : 10.1016/S0002-9440(10)65089-4

A. Eichmann and L. Yuan, Vascular development: from precursor cells to branched arterial and venous networks, The International Journal of Developmental Biology, vol.49, issue.2-3, pp.259-67, 2005.
DOI : 10.1387/ijdb.041941ae

V. Eremina and M. Sood, Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases, Journal of Clinical Investigation, vol.111, issue.5, pp.707-723, 2003.
DOI : 10.1172/JCI17423

N. Ferrara and G. Frantz, Differential Expression of the Angiogenic Factor Genes Vascular Endothelial Growth Factor (VEGF) and Endocrine Gland-Derived VEGF in Normal and Polycystic Human Ovaries, The American Journal of Pathology, vol.162, issue.6, pp.1881-93, 2003.
DOI : 10.1016/S0002-9440(10)64322-2

R. A. Ferriani and A. Ahmed, Colocalization of Acidic and Basic Fibroblast Growth Factor (FGF) in Human Placenta and the Cellular Effects of bFGF in Trophoblast Cell Line JEG-3, Growth Factors, vol.137, issue.4, pp.259-68, 1994.
DOI : 10.1083/jcb.109.1.1

J. M. Foidart and J. Hustin, The human placenta becomes haemochorial at the 13th week of pregnancy, Int J Dev Biol, vol.36, issue.3, pp.451-454, 1992.

H. M. Fraser and J. Bell, Localization and Quantification of Cyclic Changes in the Expression of Endocrine Gland Vascular Endothelial Growth Factor in the Human Corpus Luteum, The Journal of Clinical Endocrinology & Metabolism, vol.90, issue.1, pp.427-461, 2005.
DOI : 10.1210/jc.2004-0843

K. Fukushima and S. Miyamoto, Tumor Necrosis Factor and Vascular Endothelial Growth Factor Induce Endothelial Integrin Repertories, Regulating Endovascular Differentiation and Apoptosis in a Human Extravillous Trophoblast Cell Line1, Biology of Reproduction, vol.73, issue.1, pp.172-181, 2005.
DOI : 10.1095/biolreprod.104.039479

O. Genbacev and R. Joslin, Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia., Journal of Clinical Investigation, vol.97, issue.2, pp.540-50, 1996.
DOI : 10.1172/JCI118447

O. Genbacev and Y. Zhou, Regulation of Human Placental Development by Oxygen Tension, Science, vol.277, issue.5332, pp.1669-72, 1997.
DOI : 10.1126/science.277.5332.1669

P. Georgiades and A. C. Ferguson-smith, Comparative Developmental Anatomy of the Murine and Human Definitive Placentae, Placenta, vol.23, issue.1, pp.3-19, 2002.
DOI : 10.1053/plac.2001.0738

S. S. Gerety and H. U. Wang, Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development, Molecular Cell, vol.4, issue.3, pp.403-417, 1999.
DOI : 10.1016/S1097-2765(00)80342-1

G. Gerretsen and H. J. Huisjes, MORPHOLOGICAL CHANGES OF THE SPIRAL ARTERIES IN THE PLACENTAE BED IN RELATION TO PRE-ECLAMPSIA AND FETAL GROWTH RETARDATION, BJOG: An International Journal of Obstetrics and Gynaecology, vol.117, issue.9, pp.876-81, 1981.
DOI : 10.1016/0028-2243(75)90130-6

E. Geva and D. G. Ginzinger, Human Placental Vascular Development: Vasculogenic and Angiogenic (Branching and Nonbranching) Transformation Is Regulated by Vascular Endothelial Growth Factor-A, Angiopoietin-1, and Angiopoietin-2, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.9, pp.4213-4237, 2002.
DOI : 10.1210/jc.2002-020195

D. S. Goldman-wohl and I. Ariel, Tie-2 and angiopoietin-2 expression at the fetal-maternal interface: a receptor ligand model for vascular remodelling, Molecular Human Reproduction, vol.6, issue.1, pp.81-88, 2000.
DOI : 10.1093/molehr/6.1.81

H. He and V. J. Venema, Vascular Endothelial Growth Factor Signals Endothelial Cell Production of Nitric Oxide and Prostacyclin through Flk-1/KDR Activation of c-Src, Journal of Biological Chemistry, vol.274, issue.35, pp.25130-25135, 1999.
DOI : 10.1074/jbc.274.35.25130

Y. He and S. K. Smith, Alternative Splicing of Vascular Endothelial Growth Factor (VEGF)-R1 (FLT-1) pre-mRNA Is Important for the Regulation of VEGF Activity, Molecular Endocrinology, vol.13, issue.4, pp.537-582, 1999.
DOI : 10.1210/mend.13.4.0265

G. P. Heckel and C. E. Tobin, Arteriovenous shunts in the myometrium, American Journal of Obstetrics and Gynecology, vol.71, issue.1, pp.199-205, 1956.
DOI : 10.1016/0002-9378(56)90695-0

J. Hempstock and T. Cindrova-davies, Endometrial glands as a source of nutrients, growth factors and cytokines during the first trimester of human pregnancy: a morphological and immunohistochemical study, Reproductive Biology and Endocrinology, vol.2, issue.1, p.58, 2004.
DOI : 10.1186/1477-7827-2-58

M. Heroult and F. Schaffner, Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression, Experimental Cell Research, vol.312, issue.5, pp.642-50, 2006.
DOI : 10.1016/j.yexcr.2005.10.028

S. Hiratsuka and O. Minowa, Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice, Proceedings of the National Academy of Sciences, vol.95, issue.16, pp.95-9349, 1998.
DOI : 10.1073/pnas.95.16.9349

P. Hoffmann and J. J. Feige, Expression and Oxygen Regulation of Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 and Its Receptors in Human Placenta during Early Pregnancy, Endocrinology, vol.147, issue.4, pp.1675-84, 2006.
DOI : 10.1210/en.2005-0912
URL : https://hal.archives-ouvertes.fr/inserm-00375826

J. Holash and S. J. Wiegand, New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF, Oncogene, vol.18, issue.38, pp.5356-62, 1999.
DOI : 10.1038/sj.onc.1203035

M. R. Jackson and E. W. Carney, Localization of two angiogenic growth factors (PDECGF and VEGF) in human placentae throughout gestation, Placenta, vol.15, issue.4, pp.341-53, 1994.
DOI : 10.1016/0143-4004(94)90002-7

E. Jauniaux and N. Greenwold, Comparison of ultrasonographic and Doppler mapping of the intervillous circulation in normal and abnormal early pregnancies, Fertility and Sterility, vol.79, issue.1, pp.100-106, 2003.
DOI : 10.1016/S0015-0282(02)04568-5

E. Jauniaux and J. Hempstock, Trophoblastic Oxidative Stress in Relation to Temporal and Regional Differences in Maternal Placental Blood Flow in Normal and Abnormal Early Pregnancies, The American Journal of Pathology, vol.162, issue.1, pp.115-140, 2003.
DOI : 10.1016/S0002-9440(10)63803-5

E. Jauniaux and A. Watson, In-vivo measurement of intrauterine gases and acid-base values early in human pregnancy, Human Reproduction, vol.14, issue.11, pp.2901-2905, 1999.
DOI : 10.1093/humrep/14.11.2901

E. Jauniaux and A. L. Watson, Onset of Maternal Arterial Blood Flow and Placental Oxidative Stress, The American Journal of Pathology, vol.157, issue.6, pp.2111-2133, 2000.
DOI : 10.1016/S0002-9440(10)64849-3

F. J. Joubert and D. J. Strydom, (Black mamba) Venom, Hoppe-Seyler??s Zeitschrift f??r physiologische Chemie, vol.361, issue.2, pp.1787-94, 1980.
DOI : 10.1515/bchm2.1980.361.2.1787

S. A. Karumanchi and I. E. Stillman, In Vivo Rat Model of Preeclampsia, Methods Mol Med, vol.122, pp.393-402, 2006.
DOI : 10.1385/1-59259-989-3:393

A. Kaser and M. Winklmayr, The AVIT protein family: Secreted cysteine-rich vertebrate proteins with diverse functions, EMBO reports, vol.4, issue.5, pp.469-73, 2003.
DOI : 10.1038/sj.embor.embor830

P. Kaufmann and T. M. Mayhew, Aspects of Human Fetoplacental Vasculogenesis and Angiogenesis. II. Changes During Normal Pregnancy, Placenta, vol.25, issue.2-3, pp.114-140, 2004.
DOI : 10.1016/j.placenta.2003.10.009

R. L. Kendall and K. A. Thomas, Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor., Proceedings of the National Academy of Sciences, vol.90, issue.22, pp.10705-10714, 1993.
DOI : 10.1073/pnas.90.22.10705

J. C. Kingdom and P. Kaufmann, Oxygen and Placental Vascular Development, Adv Exp Med Biol, vol.474, pp.259-75, 1999.
DOI : 10.1007/978-1-4615-4711-2_20

T. Kisliouk and N. Levy, Presence and Regulation of Endocrine Gland Vascular Endothelial Growth Factor/Prokineticin-1 and Its Receptors in Ovarian Cells, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.8, pp.3700-3707, 2003.
DOI : 10.1210/jc.2003-030492

T. Kisliouk and H. Podlovni, Unique expression and regulatory mechanisms of EG-VEGF/prokineticin-1 and its receptors in the corpus luteum, Annals of Anatomy - Anatomischer Anzeiger, vol.187, issue.5-6, pp.5-6, 2005.
DOI : 10.1016/j.aanat.2005.07.005

T. Kisliouk and H. Podlovni, Prokineticins (Endocrine Gland-Derived Vascular Endothelial Growth Factor and BV8) in the Bovine Ovary: Expression and Role as Mitogens and Survival Factors for Corpus Luteum-Derived Endothelial Cells, Endocrinology, vol.146, issue.9, pp.3950-3958, 2005.
DOI : 10.1210/en.2005-0297

H. J. Kliman, Uteroplacental Blood Flow, The American Journal of Pathology, vol.157, issue.6, pp.1759-68, 2000.
DOI : 10.1016/S0002-9440(10)64813-4

H. J. Kliman and J. E. Nestler, Differentiation of Cytotrophoblasts from Human Term Placentae*, Endocrinology, vol.118, issue.4, pp.1567-82, 1986.
DOI : 10.1210/endo-118-4-1567

K. Koga and Y. Osuga, Elevated Serum Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR-1) Levels in Women with Preeclampsia, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.5, pp.2348-51, 2003.
DOI : 10.1210/jc.2002-021942

K. Kumazaki and M. Nakayama, Expression of vascular endothelial growth factor, placental growth factor, and their receptors Flt-1 and KDR in human placenta under pathologic conditions, Human Pathology, vol.33, issue.11, pp.1069-77, 2002.
DOI : 10.1053/hupa.2002.129420

C. M. Lambert and K. K. Machida, Analysis of the Prokineticin 2 System in a Diurnal Rodent, the Unstriped Nile Grass Rat (Arvicanthis niloticus), Journal of Biological Rhythms, vol.462, issue.3, pp.206-224, 2005.
DOI : 10.1177/0748730405275135

G. E. Lash and J. E. Cartwright, The Effects of Angiogenic Growth Factors on Extravillous Trophoblast Invasion and Motility, Placenta, vol.20, issue.8, pp.661-668, 1999.
DOI : 10.1053/plac.1999.0427

F. Le-noble and D. Moyon, Flow regulates arterial-venous differentiation in the chick embryo yolk sac, Development, vol.131, issue.2, pp.361-75, 2004.
DOI : 10.1242/dev.00929

J. Lecouter and N. Ferrara, EG-VEGF and the concept of tissue-specific angiogenic growth factors, Seminars in Cell & Developmental Biology, vol.13, issue.1, pp.3-8, 2002.
DOI : 10.1006/scdb.2001.0284

J. Lecouter and N. Ferrara, EG-VEGF and Bv8A Novel Family of Tissue-Selective Mediators of Angiogenesis, Endothelial Phenotype, and Function, Trends in Cardiovascular Medicine, vol.13, issue.7, pp.276-82, 2003.
DOI : 10.1016/S1050-1738(03)00110-5

J. Lecouter and J. Kowalski, Identification of an Angiogenic Mitogen Selective for Endocrine Gland Endothelium, Obstetrical and Gynecological Survey, vol.57, issue.1, pp.877-84, 2001.
DOI : 10.1097/00006254-200201000-00018

J. Lecouter and R. Lin, Endocrine gland???derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis, Nature Medicine, vol.127, issue.9, pp.913-920, 2002.
DOI : 10.1038/417405a

J. Lecouter and R. Lin, The Role of EG-VEGF in the Regulation of Angiogenesis in Endocrine Glands, Cold Spring Harbor Symposia on Quantitative Biology, vol.67, issue.0, pp.217-238, 2002.
DOI : 10.1056/NEJM199412013312203

J. Lecouter and R. Lin, Mouse Endocrine Gland-Derived Vascular Endothelial Growth Factor: A Distinct Expression Pattern from Its Human Ortholog Suggests Different Roles as a Regulator of Organ-Specific Angiogenesis, Endocrinology, vol.144, issue.6, pp.2606-2622, 2003.
DOI : 10.1210/en.2002-0146

J. Lecouter and R. Lin, The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cells, Proceedings of the National Academy of Sciences, vol.100, issue.5, pp.2685-90, 2003.
DOI : 10.1073/pnas.0337667100

J. Lecouter and C. Zlot, Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization, Proceedings of the National Academy of Sciences, vol.101, issue.48, pp.16813-16821, 2004.
DOI : 10.1073/pnas.0407697101

A. Lee and L. K. Christenson, Vascular endothelial growth factor production by human luteinized granulosa cells in vitro, Human Reproduction, vol.12, issue.12, pp.2756-61, 1997.
DOI : 10.1093/humrep/12.12.2756

R. J. Levine and S. E. Maynard, Circulating Angiogenic Factors and the Risk of Preeclampsia, New England Journal of Medicine, vol.350, issue.7, pp.672-83, 2004.
DOI : 10.1056/NEJMoa031884

H. Li and B. Gu, Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta, Placenta, vol.26, issue.2-3, pp.210-217, 2005.
DOI : 10.1016/j.placenta.2004.05.004

M. Li and C. M. Bullock, Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle, Mol Pharmacol, vol.59, issue.4, pp.692-700, 2001.

D. C. Lin and C. M. Bullock, Identification and Molecular Characterization of Two Closely Related G Protein-coupled Receptors Activated by Prokineticins/Endocrine Gland Vascular Endothelial Growth Factor, Journal of Biological Chemistry, vol.277, issue.22, pp.19276-80, 2002.
DOI : 10.1074/jbc.M202139200

R. Lin and J. Lecouter, Characterization of Endocrine Gland-derived Vascular Endothelial Growth Factor Signaling in Adrenal Cortex Capillary Endothelial Cells, Journal of Biological Chemistry, vol.277, issue.10, pp.8724-8733, 2002.
DOI : 10.1074/jbc.M110594200

Z. C. Luo and W. D. Fraser, Tracing the origins of ???fetal origins??? of adult diseases: Programming by oxidative stress?, Medical Hypotheses, vol.66, issue.1, pp.38-44, 2006.
DOI : 10.1016/j.mehy.2005.08.020

P. C. Maisonpierre and C. Suri, Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis, Science, vol.277, issue.5322, pp.55-60, 1997.
DOI : 10.1126/science.277.5322.55

A. Malassine and J. L. Frendo, A comparison of placental development and endocrine functions between the human and mouse model, Human Reproduction Update, vol.9, issue.6, pp.531-540, 2003.
DOI : 10.1093/humupd/dmg043

J. N. Martin, C. H. Jr, and . Rose, Understanding and managing HELLP syndrome: The integral role of aggressive glucocorticoids for mother and child, American Journal of Obstetrics and Gynecology, vol.195, issue.4, pp.914-948, 2006.
DOI : 10.1016/j.ajog.2005.08.044

Y. Masuda and Y. Takatsu, Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors, Biochemical and Biophysical Research Communications, vol.293, issue.1, pp.396-402, 2002.
DOI : 10.1016/S0006-291X(02)00239-5

T. M. Mayhew, Changes in Fetal Capillaries During Preplacental Hypoxia: Growth, Shape Remodelling and Villous Capillarization in Placentae from High-Altitude Pregnancies, Placenta, vol.24, issue.2-3, pp.191-199, 2003.
DOI : 10.1053/plac.2002.0895

S. E. Maynard and J. Y. Min, Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia, Journal of Clinical Investigation, vol.111, issue.5, pp.649-58, 2003.
DOI : 10.1172/JCI17189

E. A. Mcgee and A. J. Hsueh, Initial and Cyclic Recruitment of Ovarian Follicles, Endocrine Reviews, vol.21, issue.2, pp.200-214, 2000.
DOI : 10.1210/er.21.2.200

J. W. Meekins and R. Pijnenborg, A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies, BJOG: An International Journal of Obstetrics and Gynaecology, vol.88, issue.8, pp.669-74, 1994.
DOI : 10.1016/0028-2243(75)90130-6

D. Melchiorri and V. Bruno, The mammalian homologue of the novel peptide Bv8 is expressed in the central nervous system and supports neuronal survival by activating the MAP kinase/PI-3-kinase pathways, European Journal of Neuroscience, vol.1436, issue.Suppl. 24, pp.1694-702, 2001.
DOI : 10.1016/s0014-5793(99)01473-8

C. Mollay and C. Wechselberger, Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats, European Journal of Pharmacology, vol.374, issue.2, pp.189-96, 1999.
DOI : 10.1016/S0014-2999(99)00229-0

T. Nagamatsu and T. Fujii, Cytotrophoblasts Up-Regulate Soluble Fms-Like Tyrosine Kinase-1 Expression under Reduced Oxygen: An Implication for the Placental Vascular Development and the Pathophysiology of Preeclampsia, Endocrinology, vol.145, issue.11, pp.4838-4883, 2004.
DOI : 10.1210/en.2004-0533

L. Negri and R. Lattanzi, Impaired Nociception and Inflammatory Pain Sensation in Mice Lacking the Prokineticin Receptor PKR1: Focus on Interaction between PKR1 and the Capsaicin Receptor TRPV1 in Pain Behavior, Journal of Neuroscience, vol.26, issue.25, pp.6716-6743, 2006.
DOI : 10.1523/JNEUROSCI.5403-05.2006

L. Negri and R. Lattanzi, Bv8, the amphibian homologue of the mammalian prokineticins, modulates ingestive behaviour in rats, British Journal of Pharmacology, vol.80, issue.A, pp.181-91, 2004.
DOI : 10.1038/sj.bjp.0705686

G. Neufeld and T. Cohen, Vascular endothelial growth factor (VEGF) and its receptors, Faseb J, vol.13, issue.1, pp.9-22, 1999.

J. Neulen and S. Raczek, Secretion of vascular endothelial growth factor/vascular permeability factor from human luteinized granulosa cells is human chorionic gonadotrophin dependent, Molecular Human Reproduction, vol.4, issue.3, pp.203-209, 1998.
DOI : 10.1093/molehr/4.3.203

E. S. Ngan and K. Y. Lee, Endocrine Gland-Derived Vascular Endothelial Growth Factor Is Expressed in Human Peri-implantation Endometrium, But Not in Endometrial Carcinoma, Endocrinology, vol.147, issue.1, pp.88-95, 2006.
DOI : 10.1210/en.2005-0543

G. E. Palade and M. Simionescu, Structural aspects of the permeability of the microvascular endothelium, Acta Physiol Scand, vol.463, pp.11-32, 1979.

A. Papapetropoulos and G. Garcia-cardena, Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors, Lab Invest, vol.79, issue.2, pp.213-236, 1999.

S. Patan, TIE1 and TIE2 Receptor Tyrosine Kinases Inversely Regulate Embryonic Angiogenesis by the Mechanism of Intussusceptive Microvascular Growth, Microvascular Research, vol.56, issue.1, pp.1-21, 1998.
DOI : 10.1006/mvre.1998.2081

R. Pijnenborg and W. B. Robertson, THE ROLE OF OVARIAN STEROIDS IN PLACENTAL DEVELOPMENT AND ENDOVASCULAR TROPHOBLAST MIGRATION IN THE GOLDEN HAMSTER, Reproduction, vol.44, issue.1, pp.43-51, 1975.
DOI : 10.1530/jrf.0.0440043

R. Pijnenborg and W. B. Robertson, Morphological aspects of placental ontogeny and phylogeny, Placenta, vol.6, issue.2, pp.155-62, 1985.
DOI : 10.1016/S0143-4004(85)80065-5

E. Podjarny and G. Losonczy, Animal models of preeclampsia, Seminars in Nephrology, vol.24, issue.6, pp.596-606, 2004.
DOI : 10.1016/j.semnephrol.2004.07.011

B. M. Polliotti and A. G. Fry, Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia, Obstet Gynecol, vol.101, issue.6, pp.1266-74, 2003.

C. W. Pugh and P. J. Ratcliffe, Regulation of angiogenesis by hypoxia: role of the HIF system, Nature Medicine, vol.9, issue.6, pp.677-84, 2003.
DOI : 10.1038/nm0603-677

D. Qian and H. Y. Lin, Involvement of ERK1/2 pathway in TGF-?1-induced VEGF secretion in normal human cytotrophoblast cells, Molecular Reproduction and Development, vol.8, issue.2, pp.198-204, 2004.
DOI : 10.1002/mrd.20061

K. Red-horse and M. Kapidzic, EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation, Development, vol.132, issue.18, pp.4097-106, 2005.
DOI : 10.1242/dev.01971

K. Red-horse and J. Rivera, Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation, Journal of Clinical Investigation, vol.116, issue.10, pp.2643-52, 2006.
DOI : 10.1172/JCI27306.

C. W. Redman and G. P. Sacks, Preeclampsia, Obstetric Anesthesia Digest, vol.19, issue.2, pp.499-506, 1999.
DOI : 10.1097/00132582-199906000-00004

C. W. Redman and I. L. Sargent, Latest Advances in Understanding Preeclampsia, Science, vol.308, issue.5728, pp.1592-1596, 2005.
DOI : 10.1126/science.1111726

W. Risau, Mechanisms of angiogenesis, Nature, vol.386, issue.6626, pp.671-675, 1997.

W. G. Roberts and J. Delaat, Host Microvasculature Influence on Tumor Vascular Morphology and Endothelial Gene Expression, The American Journal of Pathology, vol.153, issue.4, pp.1239-1287, 1998.
DOI : 10.1016/S0002-9440(10)65668-4
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853053

F. Rodesch and P. Simon, Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy, Obstet Gynecol, vol.80, issue.2, pp.283-288, 1992.

J. Rossant and J. C. Cross, PLACENTAL DEVELOPMENT: LESSONS FROM MOUSE MUTANTS, Nature Reviews Genetics, vol.2, issue.7, pp.538-586, 2001.
DOI : 10.1038/35080570

M. Samson, F. V. Peale, and . Jr, Human Endocrine Gland-Derived Vascular Endothelial Growth Factor: Expression Early in Development and in Leydig Cell Tumors Suggests Roles in Normal and Pathological Testis Angiogenesis, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.8, pp.4078-88, 2004.
DOI : 10.1210/jc.2003-032024

T. N. Sato and Y. Tozawa, Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation, Nature, vol.376, issue.6535, pp.70-74, 1995.
DOI : 10.1038/376070a0

J. P. Schaaps and V. Tsatsaris, Shunting the intervillous space: New concepts in human uteroplacental vascularization, American Journal of Obstetrics and Gynecology, vol.192, issue.1, pp.323-355, 2005.
DOI : 10.1016/j.ajog.2004.06.066

L. Schaffer and A. Scheid, Oxygen-regulated Expression of TGF-??3, a Growth Factor Involved in Trophoblast Differentiation, Placenta, vol.24, issue.10, pp.941-50, 2003.
DOI : 10.1016/S0143-4004(03)00166-8

H. Schweitz and J. N. Bidard, Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom, Toxicon, vol.28, issue.7, pp.847-56, 1990.
DOI : 10.1016/S0041-0101(09)80007-X

H. Schweitz and P. Pacaud, , a black mamba toxin with a new and highly potent activity on intestinal contraction, FEBS Letters, vol.328, issue.3, pp.183-191, 1999.
DOI : 10.1016/S0014-5793(99)01459-3

F. Shalaby and J. Rossant, Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice, Nature, vol.376, issue.6535, pp.62-68, 1995.
DOI : 10.1038/376062a0

A. M. Sharkey and D. S. Charnock-jones, Expression of mRNA for vascular endothelial growth factor in human placenta, Reproduction, vol.99, issue.2, pp.609-624, 1993.
DOI : 10.1530/jrf.0.0990609

D. Shweiki and A. Itin, Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis., Journal of Clinical Investigation, vol.91, issue.5, pp.2235-2278, 1993.
DOI : 10.1172/JCI116450

B. Sibai and G. Dekker, Pre-eclampsia, The Lancet, vol.365, issue.9461, pp.785-99, 2005.
DOI : 10.1016/S0140-6736(05)71003-5

S. K. Smith, Angiogenesis and implantation, Hum Reprod, vol.15, issue.6, pp.59-66, 2000.

T. Soga and S. Matsumoto, Molecular cloning and characterization of prokineticin receptors, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1579, issue.2-3, pp.173-182, 2002.
DOI : 10.1016/S0167-4781(02)00546-8

A. Soghomonians and A. I. Barakat, Trophoblast Migration Under Flow Is Regulated by Endothelial Cells1, Biology of Reproduction, vol.73, issue.1, pp.14-23, 2005.
DOI : 10.1095/biolreprod.104.036509

H. Soma and K. Yoshida, Morphologic changes in the hypertensive placenta, Contrib Gynecol Obstet, vol.9, pp.58-75, 1982.

S. A. Stacker and C. Caesar, VEGF-D promotes the metastatic spread of tumor cells via the lymphatics, Nature Medicine, vol.7, issue.2, pp.186-91, 2001.
DOI : 10.1038/84635

E. Staun-ram and E. Shalev, Human trophoblast function during the implantation process, Reproductive Biology and Endocrinology, vol.3, issue.1, p.56, 2005.
DOI : 10.1186/1477-7827-3-56

P. A. Stewart and M. J. Wiley, Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras, Developmental Biology, vol.84, issue.1, pp.183-92, 1981.
DOI : 10.1016/0012-1606(81)90382-1

C. Suri and P. F. Jones, Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis, Cell, vol.87, issue.7, pp.1171-80, 1996.
DOI : 10.1016/S0092-8674(00)81813-9

H. Takahashi and M. Shibuya, The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions, Clinical Science, vol.109, issue.3, pp.227-268, 2005.
DOI : 10.1042/CS20040370

A. Tarrade and R. Lai-kuen, Characterization of Human Villous and Extravillous Trophoblasts Isolated from First Trimester Placenta, Laboratory Investigation, vol.81, issue.9, pp.1199-211, 2001.
DOI : 10.1038/labinvest.3780334

R. N. Taylor and J. Grimwood, Longitudinal serum concentrations of placental growth factor: Evidence for abnormal placental angiogenesis in pathologic pregnancies, American Journal of Obstetrics and Gynecology, vol.188, issue.1, pp.177-82, 2003.
DOI : 10.1067/mob.2003.111

M. Thomas and M. Keramidas, Role of adrenocorticotropic hormone in the development and maintenance of the adrenal cortical vasculature, Microscopy Research and Technique, vol.72, issue.3, pp.247-51, 2003.
DOI : 10.1002/jemt.10333

D. S. Torry and M. Hinrichs, Determinants of Placental Vascularity, American Journal of Reproductive Immunology, vol.122, issue.4, pp.257-68, 2004.
DOI : 10.1093/emboj/18.4.934

S. Venkatesha and M. Toporsian, Soluble endoglin contributes to the pathogenesis of preeclampsia, Nature Medicine, vol.274, issue.6, pp.642-651, 2006.
DOI : 10.1038/nm1429

M. Vikkula and L. M. Boon, Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2, Cell, vol.87, issue.7, pp.1181-90, 1996.
DOI : 10.1016/S0092-8674(00)81814-0

M. Vuckovic and J. Ponting, Expression of the vascular endothelial growth factor receptor, KDR, in human placenta, J Anat, vol.188, issue.2, pp.361-367, 1996.

P. Vuorela and O. Carpen, VEGF, its receptors and the Tie receptors in recurrent miscarriage, Molecular Human Reproduction, vol.6, issue.3, pp.276-82, 2000.
DOI : 10.1093/molehr/6.3.276

H. U. Wang and Z. F. Chen, Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4, Cell, vol.93, issue.5, pp.741-53, 1998.
DOI : 10.1016/S0092-8674(00)81436-1

J. Wang and F. Luo, VEGF expression and enhanced production by gonadotropins in ovarian epithelial tumors, International Journal of Cancer, vol.83, issue.2, pp.163-170, 2002.
DOI : 10.1002/ijc.1593

C. Wechselberger and R. Puglisi, The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes, FEBS Letters, vol.227, issue.1-2, pp.177-81, 1999.
DOI : 10.1016/S0014-5793(99)01473-8

J. Wilting and R. Birkenhager, VEGF121Induces Proliferation of Vascular Endothelial Cells and Expression offlk-1without Affecting Lymphatic Vessels of the Chorioallantoic Membrane, Developmental Biology, vol.176, issue.1, pp.76-85, 1996.
DOI : 10.1006/dbio.1996.9993

C. Wulff and M. Weigand, Angiogenesis during primate placentation in health and disease, Reproduction, vol.126, issue.5, pp.569-77, 2003.
DOI : 10.1530/rep.0.1260569

C. Wulff and H. Wilson, Hemochorial Placentation in the Primate: Expression of Vascular Endothelial Growth Factor, Angiopoietins, and Their Receptors Throughout Pregnancy1, Biology of Reproduction, vol.66, issue.3, pp.802-814, 2002.
DOI : 10.1095/biolreprod66.3.802

G. D. Yancopoulos and S. Davis, Vascular-specific growth factors and blood vessel formation, Nature, vol.407, issue.6801, pp.242-250, 2000.
DOI : 10.1038/35025215

G. D. Yancopoulos and M. Klagsbrun, Vasculogenesis, Angiogenesis, and Growth Factors: Ephrins Enter the Fray at the Border, Cell, vol.93, issue.5, pp.661-665, 1998.
DOI : 10.1016/S0092-8674(00)81426-9

J. C. Yang and L. Haworth, A Randomized Trial of Bevacizumab, an Anti???Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer, New England Journal of Medicine, vol.349, issue.5, pp.427-461, 2003.
DOI : 10.1056/NEJMoa021491

E. G. Zhang and S. K. Smith, The regulation and localization of angiopoietin-1, -2, and their receptor Tie2 in normal and pathologic human placentae, Mol Med, vol.7, issue.9, pp.624-659, 2001.

L. Zhang and N. Yang, Expression of endocrine gland-derived vascular endothelial growth factor in ovarian carcinoma, Clin Cancer Res, vol.9, issue.1, pp.264-72, 2003.

Y. Zhou and V. Bellingard, Human cytotrophoblasts promote endothelial survival and vascular remodeling through secretion of Ang2, PlGF, and VEGF-C, Developmental Biology, vol.263, issue.1, pp.114-139, 2003.
DOI : 10.1016/S0012-1606(03)00449-4

Y. Zhou and S. J. Fisher, Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?, Journal of Clinical Investigation, vol.99, issue.9, pp.2139-51, 1997.
DOI : 10.1172/JCI119387
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC508044

Y. Zhou and M. Mcmaster, Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome, The American Journal of Pathology, vol.160, issue.4, pp.1405-1428, 2002.
DOI : 10.1016/S0002-9440(10)62567-9

M. Ziche and D. Maglione, Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic, Lab Invest, vol.76, issue.4, pp.517-548, 1997.