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Theses

Etude de la transmission du virus influenza au sein de populations d'Anatidae

Abstract : Since 1997, influenza A viruses has given rise to great sanitary andeconomic interest after the emergence of a highly pathogenic subtype ofavian influenza virus H5N1. This epizooty underlined the threat that couldbe the closeness of wild and domestic birds. Ducks which were actuallyshowing reservoirs characteristics were suspected to pass on the virusthanks to their migratory habits and asymptomatic porterage.This porterage mostly involves low pathogenic viruses of numerous subtypes.Those viruses could be transmitted to domestic poultries and emerge, in thecase of H5 and H7 subtypes, in a viral highly pathogenic epizooty. Thoseepizooties may have major economic (average 100% mortality) and sanitary(possible transmission to humans) consequences.Our study aims to characterize the infection and the transmission of lowpathogenic avian influenza viruses, after experimental inoculation tosurface and diving ducks. It suggests setting up epidemiologic surveillancemethods of avian influenza viruses after the arrival of migratory birds inmost important wetlands, which are close to major poultry breeding regions(The Dombes for instance).
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Aymen Mamlouk. Etude de la transmission du virus influenza au sein de populations d'Anatidae. Médecine humaine et pathologie. Université de Grenoble, 2011. Français. ⟨NNT : 2011GRENS031⟩. ⟨tel-00656003v2⟩

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