Contrôle faisceau et dosimétrie en protonthérapie

Abstract : This thesis deals with beam control devices for scanned proton beams. The IBA society (Ion Beam Applications) has developed a new dynamic beam delivery system called Pencil Beam Scanning. IBA needed a monitor unit to equip its proton beam lines dedicated to the PBS system and called upon the medical applications group of the Laboratoire de Physique Corpusculaire de Caen. In 2008, this group realized, in collaboration with IBA, an ionization chamber monitor IC2/3 for the IBA dedicated PBS nozzle. This device verifies the agreement between planned and delivered particular fluence. The first part of this thesis focused on the characterization of this monitor unit. Proton beams of different clinical energies, positions and dose rates were used to check the specifications requested by IBA. After the introduction about the Proton Therapy, the validation step of IC2/3 is exposed. Information provided by IC2/3 makes it possible beam control in terms of fluence but does not ensure quality control in terms of spatial dose distribution. The second part of the work was devoted to the conception of a beam control device for scanned proton beams. Called Compass PT, it will allow a reconstruction of the spatial dose distribution delivered to the patient. The specifications definition and the conception studies are presented in this thesis. All this work has led to recommendations for the realization of this device and new research prospects.
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Submitted on : Monday, November 7, 2011 - 10:41:37 AM
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C. Courtois. Contrôle faisceau et dosimétrie en protonthérapie. Physique Nucléaire Théorique [nucl-th]. Université de Caen, 2011. Français. ⟨tel-00638702⟩

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