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Approche intégrée de la gestion environnementale Des produits pharmaceutiques dans des rejets de Stations d'épuration urbaines et leur milieu récepteur : occurrence, impact et traitements tertiaires d'élimination

Abstract : Pharmaceutical products (PPs), widely consumed by population and discharged in the environment through wastewater treatment process (WTP), are sources of aquatic ecosystems contamination. Environmental risk assessment for these substances involves the accurate quantification of their concentrations and the evaluation of their toxicity for exposed species. Our study dealing with a dozen of representative pharmaceutical compounds was conducted in Southeast France. A LC-MS/MS detection method was developed and a sampling campaign was carried out on 7 urban WTP and the natural waters where they discharge (rivers of the Gard and pond) in order to assess PPs contamination level. Toxicity of PPs was estimated using bioluminescent and growth inhibition tests (Microtox, ToxScreen and Protoxkit). Experiments were conducted to evaluate UV photolysis and activated carbon adsorption capacities for the removal of these compounds. Measurements for samples collected highlight the occurrence of PPs in WTP effluent of Southeast region at concentrations ranging from 10 to 1000 ng L-1 and reaching hundreds of ng L-1 in the downstream surface waters. Comparison between the level of exposure and experimental toxicity values completed by literature data suggests that only 3 compounds (propranolol, ibuprofen and diclofénac) may induce a low risk at a local scale (rivers of Gard). Complementary treatments of the STP effluents by UV photolysis and activated carbon adsorption prove to be efficient to remove most of the 12 studied PPs and should be considered to reduce the presence and the impact of pharmaceutical products in the environment.
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https://tel.archives-ouvertes.fr/tel-00625971
Contributor : Clémence Coetsier <>
Submitted on : Friday, September 23, 2011 - 9:54:00 AM
Last modification on : Wednesday, June 24, 2020 - 4:18:36 PM
Long-term archiving on: : Saturday, December 24, 2011 - 2:21:28 AM

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  • HAL Id : tel-00625971, version 1

Citation

Clémence Coetsier. Approche intégrée de la gestion environnementale Des produits pharmaceutiques dans des rejets de Stations d'épuration urbaines et leur milieu récepteur : occurrence, impact et traitements tertiaires d'élimination. Génie des procédés. Université Montpellier II - Sciences et Techniques du Languedoc, 2009. Français. ⟨tel-00625971⟩

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