Abstract : In the first part of the doctoral thesis are presented the local and global kinematics sizes which are acting on the human body. This is followsed with the optical methods by which we can measure the vibrations produced by the machine-tools and them action on the human hand-arm system during the work activity. In the third part are given the effects of vibrations that occur on the hand-arm system during the exposure of vibrations. The fourth part of this thesis contains the theorical basis of optical techniques used for vibrations measurement. Chapter five presents the experimental methodology of vibrations measurement in comparition betsween the two methods: classical and optical. The results of measurement are given in chapter six of the thesis. In chapter seven is given the mechanical and mathematical modeling of human hand-arm system with three degrees of freedom and the eighth chapter contains the final conclusions, the personal contributions and the future research directions.