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Estimation des déformations du ventricule gauche sur des séquences ciné-IRM non-marquées

Abstract : This thesis presents a new concept for the assessment of cardiac deformation from standard cine-MRI without requiring tagged MRI. We have adapted the level set method to segment the myocardium and to evaluate the endocardial and epicardial velocity contours. The segmentation process is directly applied on a pseudo-volumic 2D+t set of images. This leads to an efficient segmentation method that both take into account spatial and temporal continuity constraints. Then, we evaluated the displacement of detected endocardial and epicardial contours by a levelset based matching procedure. The velocity flow in the myocardial wall is assessed by an optical flow method constrained with the contour displacement. Finally, from the velocity flow, we derive relevant measurements of the cardiac contraction. The validation of the method is performed on synthetic image sequences, and by comparing our measurements to those obtained on the same patients with the HARmonic Phase reference (HARP) method applied on matched tagged MR images. The results of this method are encouraging, they are practically identical to those HARP approach. This method presents two main advantages: first it exploits standard untagged cine-MRI, secondly it leads to high spatial resolution strain assessments. This method is readily available and has potential to make the assessment of left ventricular myocardial deformation accessible for clinical use from a set of cardiac cine MR acquisitions
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Submitted on : Friday, April 16, 2010 - 1:36:10 PM
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  • HAL Id : tel-00473769, version 1



Solofohery Randrianarisolo. Estimation des déformations du ventricule gauche sur des séquences ciné-IRM non-marquées. Autre. Université Paris-Est, 2009. Français. ⟨NNT : 2009PEST0022⟩. ⟨tel-00473769⟩



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