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General methods All reactions were performed under an inert atmosphere of argon or nitrogen using standard high-vacuum or Schlenk techniques or in an MBraun glovebox containing less than 1 ppm oxygen and water. Solvents were distilled from appropriate drying agents or were dispensed from a solvent purification system from Innovative Technology, other anhydrous solvents were purchased from Aldrich and degassed prior to use by purging with dry argon and were kept over molecular sieves, Acta J. Mol. Catal. A-Chem, vol.356, issue.173, pp.446-450, 1952. ,
GC-MS spectra were recorded on GC MS Agilent 5973 equipped with a Electronic Ionization chamber (E.I) HRMS analyses were performed by the Mass Spectrometry Facility of the Institute of Chemical Research of Catalonia (ICIQ) in Tarragona (Spain) Elemental analyses were performed at the Universidad Complutense de Madrid. The CIF files of crystal structures 107 and 108 have been deposited with the CCDC, CCDC- 688389 and 688388, respectively Copies of the data can be obtained free of charge on applications to CCDC, p.12 ,
CH(CH 3 ) 2 ), CH, CH(CH 3 ) 2 ), 27.2 (CH 3 , CH(CH 3 ) 2 ) CH(CH 3 ) 2 ) CH(CH 3 ) 2 ) CH(CH 3 ) 2 ) CH(CH 3 ) 2 ) ,
CDCl 3 ) ? 7, NMR: (400 MHz, p.8386 ,
The reaction mixture was then dissolved in 30 mL of EtOAc and washed once with a 01N HCl solution (20 mL) After adjusting the pH to 5 with a 3N NaOH solution, the aqueous phase was extracted six times with EtOAc. Subsequent flash chromatography on silica gel (EtOAc ,
The reaction mixture was then dissolved in 30 mL of EtOAc and washed once with a 01N HCl solution (20 mL) After adjusting the pH to 5 with a 3N NaOH solution, the aqueous phase was extracted six times with EtOAc. Subsequent flash chromatography on silica gel (EtOAc ,
CDCl 3 ) ? 8, NMR: (400 MHz, pp.41-732 ,
81 (s, 3H, O-CH 3 ,
CDCl 3 ) ? 7, NMR: (400 MHz, p.22 ,
23 (s, 3H, CH 3 ), 1.58-1.50 (m, 4H ,
CDCl 3 ) ? -113, 376 MHz ,
CDCl 3 ) ? 7.65 (dd, 3 J(H,H) = 8.0 Hz, NMR: (400 MHz, pp.7-46 ,
CDCl 3 ) ? 7, NMR: (400 MHz, pp.4-82 ,
CDCl 3 ) ? 7, NMR: (400 MHz, pp.4-78 ,
CDCl 3 ) ? 10.66 (bs, NMR: (400 MHz, p.67 ,
CDCl 3 ) ? 7, NMR: (400 MHz, pp.35-42 ,
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obtenir des outils efficaces utilisables en synthèse nucléosidique, nous avons développés des nouveaux complexes au palladium portant un ligand CNH et testé leurs réactivités dans des réactions de ,
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