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Etude et développement d'une plateforme microfluidique dédiée à des applications biologiques. Intégration d'un actionneur magnétique sur substrat souple

Abstract : The profound changes observed over the last twenty five years in the electronics world currently haves courses in biology, partly thanks to biotechnology. The concept commonly called "lab-on-chip" (LOC) owes its growth to the considerable effort that has been conducted on technology development of micro-fabrication. The number of technological tools currently available for the manufacture of microfluidic networks is important but the realization of complex three-dimensional systems remains a challenge. The development of micro and nanotechnology for new materials such as polymers, and especially the SU-8, opened the way for more sophisticated integration as we present it in this work. We expose the details of an approach in the design, modeling and fabrication of magnetic actuators integrated into SU-8 microfluidic networks for magnetic beads handling; all being developed on a flexible substrate of PET. The development of characterizations tools systems was also presented. They permit the establishment of an experimental protocol to assess and quantify the different electrical, thermal, fluidic and magnetic parameters contributing to obtain a LOC device in the efficient movement of fluids, trapping of magnetic balls, transfer of one area to another and to their orientation through preferred channels.
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https://tel.archives-ouvertes.fr/tel-00450545
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Submitted on : Tuesday, January 26, 2010 - 3:31:17 PM
Last modification on : Friday, January 10, 2020 - 9:08:08 PM
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  • HAL Id : tel-00450545, version 1

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Rémy Fulcrand. Etude et développement d'une plateforme microfluidique dédiée à des applications biologiques. Intégration d'un actionneur magnétique sur substrat souple. Micro et nanotechnologies/Microélectronique. Université Paul Sabatier - Toulouse III, 2009. Français. ⟨tel-00450545⟩

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