N. Alic, N. Ayoub, E. Landrieux, E. Favry, P. Baudouin-cornu et al., Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription, Proceedings of the National Academy of Sciences, vol.104, issue.25, pp.10400-10405, 2007.
DOI : 10.1073/pnas.0704116104

C. Allmang and D. Tollervey, The role of the 3??? external transcribed spacer in yeast pre-rRNA processing, Journal of Molecular Biology, vol.278, issue.1, pp.67-78, 1998.
DOI : 10.1006/jmbi.1998.1693

J. S. Andersen, C. E. Lyon, A. H. Fox, A. K. Leung, Y. W. Lam et al., Directed Proteomic Analysis of the Human Nucleolus, Current Biology, vol.12, issue.1, pp.1-11, 2002.
DOI : 10.1016/S0960-9822(01)00650-9

P. Aprikian, B. Moorefield, and R. H. Reeder, New Model for the Yeast RNA Polymerase I Transcription Cycle, Molecular and Cellular Biology, vol.21, issue.15, pp.4847-4855, 2001.
DOI : 10.1128/MCB.21.15.4847-4855.2001

D. E. Awrey, R. G. Weilbaecher, S. A. Hemming, S. M. Orlicky, C. M. Kane et al., Transcription Elongation through DNA Arrest Sites. A MULTISTEP PROCESS INVOLVING BOTH RNA POLYMERASE II SUBUNIT RPB9 AND TFIIS, Journal of Biological Chemistry, vol.272, issue.23, pp.14747-14754, 1997.
DOI : 10.1074/jbc.272.23.14747

R. Azzam, S. L. Chen, W. Shou, A. S. Mah, G. Alexandru et al., Phosphorylation by Cyclin B-Cdk Underlies Release of Mitotic Exit Activator Cdc14 from the Nucleolus, Science, vol.305, issue.5683, pp.516-519, 2004.
DOI : 10.1126/science.1099402

A. S. Balajee, A. May, G. L. Dianov, E. C. Friedberg, and V. A. Bohr, Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells, Proceedings of the National Academy of Sciences, vol.94, issue.9, pp.4306-4311, 1997.
DOI : 10.1073/pnas.94.9.4306

N. Ban, P. Nissen, J. Hansen, P. B. Moore, and T. A. Steitz, The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 A Resolution, Science, vol.289, issue.5481, pp.905-920, 2000.
DOI : 10.1126/science.289.5481.905

F. Beckouet, S. Labarre-mariotte, B. Albert, Y. Imazawa, M. Werner et al., Two RNA Polymerase I Subunits Control the Binding and Release of Rrn3 during Transcription, Molecular and Cellular Biology, vol.28, issue.5, pp.1596-1605, 2008.
DOI : 10.1128/MCB.01464-07

URL : https://hal.archives-ouvertes.fr/hal-00309037

M. Bier, S. Fath, and H. Tschochner, The composition of the RNA polymerase I transcription machinery switches from initiation to elongation mode, FEBS Letters, vol.21, issue.1-2, pp.41-46, 2004.
DOI : 10.1016/S0014-5793(04)00311-4

H. Bierhoff, M. Dundr, A. A. Michels, and I. Grummt, Phosphorylation by Casein Kinase 2 Facilitates rRNA Gene Transcription by Promoting Dissociation of TIF-IA from Elongating RNA Polymerase I, Molecular and Cellular Biology, vol.28, issue.16, pp.4988-4998, 2008.
DOI : 10.1128/MCB.00492-08

M. Biggiogera, S. Fakan, S. H. Kaufmann, A. Black, J. H. Shaper et al., Simultaneous immunoelectron microscopic visualization of protein B23 and C23 distribution in the HeLa cell nucleolus., Journal of Histochemistry & Cytochemistry, vol.37, issue.9, pp.1371-1374, 1989.
DOI : 10.1177/37.9.2768807

J. Bodem, G. Dobreva, U. Hoffmann-rohrer, S. Iben, H. Zentgraf et al., TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p, EMBO reports, vol.69, issue.2, pp.171-175, 2000.
DOI : 10.1093/embo-reports/kvd032

F. M. Boisvert, S. Van-koningsbruggen, J. Navascues, and A. I. Lamond, The multifunctional nucleolus, Nature Reviews Molecular Cell Biology, vol.20, issue.7, pp.574-585, 2007.
DOI : 10.1038/nrm2184

J. Bradsher, J. Auriol, L. Proietti-de-santis, S. Iben, J. L. Vonesch et al., CSB Is a Component of RNA Pol I Transcription, Molecular Cell, vol.10, issue.4, pp.819-829, 2002.
DOI : 10.1016/S1097-2765(02)00678-0

Y. Brandenburger, A. Jenkins, D. J. Autelitano, and R. D. Hannan, Increased expression of UBF is a critical determinant for rRNA synthesis and hypertrophic growth of cardiac myocytes, The FASEB Journal, vol.15, pp.2051-2053, 2001.
DOI : 10.1096/fj.01-0853fje

E. J. Brown, M. W. Albers, T. B. Shin, K. Ichikawa, C. T. Keith et al., A mammalian protein targeted by G1-arresting rapamycin???receptor complex, Nature, vol.369, issue.6483, pp.756-758, 1994.
DOI : 10.1038/369756a0

A. Budde and I. Grummt, p53 represses ribosomal gene transcription, Oncogene, vol.18, issue.4, pp.1119-1124, 1999.
DOI : 10.1038/sj.onc.1202402

P. Cabart and I. Kalousek, Early gene expression of both RNA polymerase I transcription factors UBF1 and UBF2 precedes ribosomal RNA synthesis during lymphocyte mitogenic stimulation, Cell Mol Biol, vol.44, pp.343-350, 1998.

M. Catala, M. Tremblay, E. Samson, A. Conconi, A. Elela et al., Deletion of Rnt1p Alters the Proportion of Open versus Closed rRNA Gene Repeats in Yeast, Molecular and Cellular Biology, vol.28, issue.2, pp.619-629, 2008.
DOI : 10.1128/MCB.01805-07

A. H. Cavanaugh, A. Evans, and L. I. Rothblum, Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I, Gene Expr, vol.14, pp.131-147, 2008.

A. H. Cavanaugh, W. M. Hempel, L. J. Taylor, V. Rogalsky, G. Todorov et al., Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product, Nature, vol.374, issue.6518, pp.177-180, 1995.
DOI : 10.1038/374177a0

A. H. Cavanaugh, I. Hirschler-laszkiewicz, Q. Hu, M. Dundr, T. Smink et al., Rrn3 Phosphorylation Is a Regulatory Checkpoint for Ribosome Biogenesis, Journal of Biological Chemistry, vol.277, issue.30, pp.27423-27432, 2002.
DOI : 10.1074/jbc.M201232200

S. Chedin, A. Laferte, T. Hoang, D. L. Lafontaine, M. Riva et al., Is ribosome synthesis controlled by pol I transcription? Cell Cycle, pp.11-15, 2007.

S. Chédin, M. L. Ferri, G. Peyroche, J. C. Andrau, S. Jourdain et al., The Yeast RNA Polymerase III Transcription Machinery: A Paradigm for Eukaryotic Gene Activation, Cold Spring Harbor Symposia on Quantitative Biology, vol.90, issue.0, pp.381-389, 1998.
DOI : 10.1016/S0968-0004(00)88977-X

J. A. Claypool, S. L. French, K. Johzuka, K. Eliason, L. Vu et al., Tor Pathway Regulates Rrn3p-dependent Recruitment of Yeast RNA Polymerase I to the Promoter but Does Not Participate in Alteration of the Number of Active Genes, Molecular Biology of the Cell, vol.15, issue.2, pp.946-956, 2004.
DOI : 10.1091/mbc.E03-08-0594

A. Clemente-blanco, M. Mayan-santos, D. A. Schneider, F. Machin, A. Jarmuz et al., Cdc14 inhibits transcription by RNA polymerase I during anaphase, Nature, vol.10, issue.7235, pp.219-222, 2009.
DOI : 10.1038/nature07652

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445138

C. Closs and P. Kempe, [A differential view and validation of the life-satisfaction construct: an analysis of proven procedures and recommendations for a methodologically based approach in measuring the dimensions of this construct], Z Gerontol, vol.19, pp.47-55, 1986.

D. Cmarko, P. J. Verschure, L. I. Rothblum, D. Hernandez-verdun, F. Amalric et al., Ultrastructural analysis of nucleolar transcription in cells microinjected with 5-bromo-UTP, Histochemistry and Cell Biology, vol.113, issue.3, pp.181-187, 2000.
DOI : 10.1007/s004180050437

L. Comai, Mechanism of RNA Polymerase I Transcription, Adv Protein Chem, vol.67, pp.123-155, 2004.
DOI : 10.1016/S0065-3233(04)67005-7

A. Conconi, R. M. Widmer, T. Koller, and J. M. Sogo, Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle, Cell, vol.57, issue.5, pp.753-761, 1989.
DOI : 10.1016/0092-8674(89)90790-3

J. L. Crespo and M. N. Hall, Elucidating TOR Signaling and Rapamycin Action: Lessons from Saccharomyces cerevisiae, Microbiology and Molecular Biology Reviews, vol.66, issue.4, pp.579-591, 2002.
DOI : 10.1128/MMBR.66.4.579-591.2002

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134654

D. 'amours, D. Stegmeier, F. Amon, and A. , Cdc14 and Condensin Control the Dissolution of Cohesin-Independent Chromosome Linkages at Repeated DNA, Cell, vol.117, issue.4, pp.455-469, 2004.
DOI : 10.1016/S0092-8674(04)00413-1

S. Denissov, M. Van-driel, R. Voit, M. Hekkelman, T. Hulsen et al., Identification of novel functional TBP-binding sites and general factor repertoires, The EMBO Journal, vol.434, issue.4, pp.944-954, 2007.
DOI : 10.1038/sj.emboj.7601550

D. Bacco, A. Gill, and G. , SUMO-Specific Proteases and the Cell Cycle, Cell Cycle, vol.5, issue.20, pp.2310-2313, 2006.
DOI : 10.4161/cc.5.20.3367

G. Dieci and A. Sentenac, Facilitated Recycling Pathway for RNA Polymerase III, Cell, vol.84, issue.2, pp.245-252, 1996.
DOI : 10.1016/S0092-8674(00)80979-4

F. Dragon, J. E. Gallagher, P. A. Compagnone-post, B. M. Mitchell, K. A. Porwancher et al., A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis, Nature, vol.180, issue.6892, pp.967-970, 2002.
DOI : 10.1073/PNAS.97.24.13027

C. Ducrot, O. Lefebvre, E. Landrieux, J. Guirouilh-barbat, A. Sentenac et al., Reconstitution of the Yeast RNA Polymerase III Transcription System with All Recombinant Factors, Journal of Biological Chemistry, vol.281, issue.17, pp.11685-11692, 2006.
DOI : 10.1074/jbc.M600101200

M. Dundr, T. Misteli, and M. O. Olson, The Dynamics of Postmitotic Reassembly of the Nucleolus, The Journal of Cell Biology, vol.8, issue.3, pp.433-446, 2000.
DOI : 10.1083/jcb.129.3.561

E. Hage, A. Koper, M. Kufel, J. Tollervey, and D. , Efficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeast, Genes & Development, vol.22, issue.8, pp.1069-1081, 2008.
DOI : 10.1101/gad.463708

S. G. Elliott and C. S. Mclaughlin, Regulation of RNA synthesis in yeast III, MGG Molecular & General Genetics, vol.25, issue.3, pp.237-243, 1979.
DOI : 10.1007/BF00382269

D. A. Erie, T. D. Yager, V. Hippel, and P. H. , The Single-Nucleotide Addition Cycle in Transcription: a Biophysical and Biochemical Perspective, Annual Review of Biophysics and Biomolecular Structure, vol.21, issue.1, pp.379-415, 1992.
DOI : 10.1146/annurev.bb.21.060192.002115

S. Fath, P. Milkereit, G. Peyroche, M. Riva, C. Carles et al., Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I, Proceedings of the National Academy of Sciences, vol.98, issue.25, pp.14334-14339, 2001.
DOI : 10.1073/pnas.231181398

K. Fatyol and I. Grummt, Proteasomal ATPases are associated with rDNA: The ubiquitin proteasome system plays a direct role in RNA polymerase I transcription, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, vol.1779, issue.12, pp.850-859, 2008.
DOI : 10.1016/j.bbagrm.2008.08.010

A. Ferdous, F. Gonzalez, L. Sun, T. Kodadek, and S. A. Johnston, The 19S Regulatory Particle of the Proteasome Is Required for Efficient Transcription Elongation by RNA Polymerase II, Molecular Cell, vol.7, issue.5, pp.981-991, 2001.
DOI : 10.1016/S1097-2765(01)00250-7

S. L. French, Y. N. Osheim, F. Cioci, M. Nomura, and A. L. Beyer, In Exponentially Growing Saccharomyces cerevisiae Cells, rRNA Synthesis Is Determined by the Summed RNA Polymerase I Loading Rate Rather than by the Number of Active Genes, Molecular and Cellular Biology, vol.23, issue.5, pp.1558-1568, 2003.
DOI : 10.1128/MCB.23.5.1558-1568.2003

M. Fromont-racine, B. Senger, C. Saveanu, and F. Fasiolo, Ribosome assembly in eukaryotes, Gene, vol.313, pp.17-42, 2003.
DOI : 10.1016/S0378-1119(03)00629-2

URL : https://hal.archives-ouvertes.fr/pasteur-01404699

O. Gadal, S. Labarre, C. Boschiero, and P. Thuriaux, Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system, The EMBO Journal, vol.21, issue.20, pp.5498-5507, 2002.
DOI : 10.1093/emboj/cdf539

T. Gautier, M. Robert-nicoud, M. N. Guilly, and D. Hernandez-verdun, Relocation of nucleolar proteins around chromosomes at mitosis. A study by confocal laser scanning microscopy, J Cell Sci, vol.102, pp.729-737, 1992.

J. Gerber, A. Reiter, R. Steinbauer, S. Jakob, C. D. Kuhn et al., Site specific phosphorylation of yeast RNA polymerase I, Nucleic Acids Research, vol.36, issue.3, pp.793-802, 2008.
DOI : 10.1093/nar/gkm1093

A. Ghavidel and M. C. Schultz, TATA Binding Protein-Associated CK2 Transduces DNA Damage Signals to the RNA Polymerase III Transcriptional Machinery, Cell, vol.106, issue.5, pp.575-584, 2001.
DOI : 10.1016/S0092-8674(01)00473-1

H. Ginisty, F. Amalric, and P. Bouvet, Nucleolin functions in the first step of ribosomal RNA processing, The EMBO Journal, vol.17, issue.5, pp.1476-1486, 1998.
DOI : 10.1093/emboj/17.5.1476

J. J. Gorski, S. Pathak, K. Panov, T. Kasciukovic, T. Panova et al., A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription, The EMBO Journal, vol.266, issue.6, pp.1560-1568, 2007.
DOI : 10.1038/sj.emboj.7601601

S. A. Gorski, S. K. Snyder, S. John, I. Grummt, and T. Misteli, Modulation of RNA Polymerase Assembly Dynamics in Transcriptional Regulation, Molecular Cell, vol.30, issue.4, pp.486-497, 2008.
DOI : 10.1016/j.molcel.2008.04.021

I. Grummt, Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo., Proc. Natl. Acad. Sci. USA, pp.727-731, 1981.
DOI : 10.1073/pnas.78.2.727

I. Grummt, Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I, Prog Nucleic Acid Res Mol Biol, vol.62, pp.109-154, 1999.
DOI : 10.1016/S0079-6603(08)60506-1

I. Grummt, U. Maier, A. Ohrlein, N. Hassouna, and J. P. Bachellerie, Transcription of mouse rDNA terminates downstream of the 3??? end of 28S RNA and involves interaction of factors with repeated sequences in the 3??? spacer, Cell, vol.43, issue.3, pp.801-810, 1985.
DOI : 10.1016/0092-8674(85)90253-3

I. Grummt, V. A. Smith, and F. Grummt, Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase, Cell, vol.7, issue.3, pp.439-445, 1976.
DOI : 10.1016/0092-8674(76)90174-4

T. Haaf, D. L. Hayman, and M. Schmid, Quantitative determination of rDNA transcription units in vertebrate cells, Experimental Cell Research, vol.193, issue.1, pp.78-86, 1991.
DOI : 10.1016/0014-4827(91)90540-B

M. M. Haltiner, S. T. Smale, and R. Tjian, Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis., Molecular and Cellular Biology, vol.6, issue.1, pp.227-235, 1986.
DOI : 10.1128/MCB.6.1.227

K. M. Hannan, Y. Brandenburger, A. Jenkins, K. Sharkey, A. Cavanaugh et al., mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF??, Molecular and Cellular Biology, vol.23, issue.23, pp.8862-8877, 2003.
DOI : 10.1128/MCB.23.23.8862-8877.2003

K. M. Hannan, B. K. Kennedy, A. H. Cavanaugh, R. D. Hannan, I. Hirschler-laszkiewicz et al., RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest, Oncogene, vol.19, issue.31, pp.3487-3497, 2000.
DOI : 10.1038/sj.onc.1203690

G. A. Hartzog, T. Wada, H. Handa, and F. Winston, Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces??cerevisiae, Genes & Development, vol.12, issue.3, pp.357-369, 1998.
DOI : 10.1101/gad.12.3.357

J. Heitman, N. R. Movva, and M. N. Hall, Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast, Science, vol.253, issue.5022, pp.905-909, 1991.
DOI : 10.1126/science.1715094

J. Heix, A. Vente, R. Voit, A. Budde, T. M. Michaelidis et al., Mitotic silencing of human rRNA synthesis: inactivation of the promoter selectivity factor SL1 by cdc2/cyclin B-mediated phosphorylation, The EMBO Journal, vol.17, issue.24, pp.7373-7381, 1998.
DOI : 10.1093/emboj/17.24.7373

D. Hernandez-verdun, P. Roussel, and J. Gebrane-younes, Emerging concepts of nucleolar assembly, J Cell Sci, vol.115, pp.2265-2270, 2002.

R. D. Hontz, S. L. French, M. L. Oakes, P. Tongaonkar, M. Nomura et al., Transcription of Multiple Yeast Ribosomal DNA Genes Requires Targeting of UAF to the Promoter by Uaf30, Molecular and Cellular Biology, vol.28, issue.21, pp.6709-6719, 2008.
DOI : 10.1128/MCB.00703-08

R. Huang, T. Wu, L. Xu, A. Liu, Y. Ji et al., Upstream binding factor up-regulated in hepatocellular carcinoma is related to the survival and cisplatin-sensitivity of cancer cells, The FASEB Journal, vol.16, issue.3, pp.293-301, 2002.
DOI : 10.1096/fj.01-0687com

R. C. Huang, N. Maheshwari, and J. Bonner, Enzymatic synthes is of RNA, Biochemical and Biophysical Research Communications, vol.3, issue.6, pp.689-694, 1960.
DOI : 10.1016/0006-291X(60)90088-7

J. Hurwitz, A. Bresler, and R. Diringer, The enzymic incorporation of ribonucleotides into polyribonucleotides and the effect of DNA, Biochemical and Biophysical Research Communications, vol.3, issue.1, pp.15-19, 1960.
DOI : 10.1016/0006-291X(60)90094-2

S. Iben, H. Tschochner, M. Bier, D. Hoogstraten, P. Hozak et al., TFIIH Plays an Essential Role in RNA Polymerase I Transcription, Cell, vol.109, issue.3, pp.297-306, 2002.
DOI : 10.1016/S0092-8674(02)00729-8

URL : http://doi.org/10.1016/s0092-8674(02)00729-8

M. R. Jacobson and T. Pederson, Localization of signal recognition particle RNA in the nucleolus of mammalian cells, Proceedings of the National Academy of Sciences, vol.95, issue.14, pp.7981-7986, 1998.
DOI : 10.1073/pnas.95.14.7981

P. Jansa, C. Burek, E. E. Sander, and I. Grummt, The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I, Nucleic Acids Research, vol.29, issue.2, pp.423-429, 2001.
DOI : 10.1093/nar/29.2.423

H. M. Jantzen, A. M. Chow, D. S. King, and R. Tjian, Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription., Genes & Development, vol.6, issue.10, pp.1950-1963, 1992.
DOI : 10.1101/gad.6.10.1950

K. Johzuka, M. Terasawa, H. Ogawa, T. Ogawa, and T. Horiuchi, Condensin Loaded onto the Replication Fork Barrier Site in the rRNA Gene Repeats during S Phase in a FOB1-Dependent Fashion To Prevent Contraction of a Long Repetitive Array in Saccharomyces cerevisiae, Molecular and Cellular Biology, vol.26, issue.6, pp.2226-2236, 2006.
DOI : 10.1128/MCB.26.6.2226-2236.2006

N. C. Jones, P. W. Rigby, and E. B. Ziff, Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses., Genes & Development, vol.2, issue.3, pp.267-281, 1988.
DOI : 10.1101/gad.2.3.267

P. Jordan, M. Mannervik, L. Tora, and M. Carmo-fonseca, In vivo evidence that TATA-binding protein/SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive, The Journal of Cell Biology, vol.133, issue.2, pp.225-234, 1996.
DOI : 10.1083/jcb.133.2.225

Q. Ju and J. R. Warner, Ribosome synthesis during the growth cycle ofSaccharomyces cerevisiae, Yeast, vol.194, issue.2, pp.151-157, 1994.
DOI : 10.1002/yea.320100203

G. A. Kassavetis and E. P. Geiduschek, Transcription factor TFIIIB and transcription by RNA polymerase III: Figure 1, Biochemical Society Transactions, vol.34, issue.6, pp.1082-1087, 2006.
DOI : 10.1042/BST0341082

J. Kawauchi, H. Mischo, P. Braglia, A. Rondon, and N. J. Proudfoot, Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination, Genes & Development, vol.22, issue.8, pp.1082-1092, 2008.
DOI : 10.1101/gad.463408

J. Keener, C. A. Josaitis, J. A. Dodd, and M. Nomura, Reconstitution of Yeast RNA Polymerase I Transcription in Vitro from Purified Components. TATA-BINDING PROTEIN IS NOT REQUIRED FOR BASAL TRANSCRIPTION, Journal of Biological Chemistry, vol.273, issue.50, pp.33795-33802, 1998.
DOI : 10.1074/jbc.273.50.33795

D. A. Keys, B. S. Lee, J. A. Dodd, T. T. Nguyen, L. Vu et al., Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex., Genes & Development, vol.10, issue.7, pp.887-903, 1996.
DOI : 10.1101/gad.10.7.887

D. A. Keys, L. Vu, J. S. Steffan, J. A. Dodd, R. T. Yamamoto et al., RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae., Genes & Development, vol.8, issue.19, pp.2349-2362, 1994.
DOI : 10.1101/gad.8.19.2349

D. R. Kief and J. R. Warner, Coordinate control of syntheses of ribosomal ribonucleic acid and ribosomal proteins during nutritional shift-up in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.1, issue.11, pp.1007-1015, 1981.
DOI : 10.1128/MCB.1.11.1007

B. Knibiehler, C. Mirre, A. Navarro, and R. Rosset, Studies on chromatin organization in a nucleolus without fibrillar centres. Presence of a sub-nucleolar structure in KCo cells of Drosophila, Cell Tissue Res, vol.236, pp.279-288, 1984.

B. Knibiehler, C. Mirre, and R. Rosset, Nucleolar organizer structure and activity in a nucleolus without fibrillar centres: the nucleolus in an established Drosophila cell line, J Cell Sci, vol.57, pp.351-364, 1982.

T. Kobayashi, D. J. Heck, M. Nomura, and T. Horiuchi, Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I, Genes & Development, vol.12, issue.24, pp.3821-3830, 1998.
DOI : 10.1101/gad.12.24.3821

N. J. Krogan, J. Dover, A. Wood, J. Schneider, J. Heidt et al., The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation, Molecular Cell, vol.11, issue.3, pp.721-729, 2003.
DOI : 10.1016/S1097-2765(03)00091-1

N. J. Krogan, M. Kim, S. H. Ahn, G. Zhong, M. S. Kobor et al., RNA Polymerase II Elongation Factors of Saccharomyces cerevisiae: a Targeted Proteomics Approach, Molecular and Cellular Biology, vol.22, issue.20, pp.6979-6992, 2002.
DOI : 10.1128/MCB.22.20.6979-6992.2002

A. Kuhn, A. Vente, M. Doree, and I. Grummt, Mitotic phosphorylation of the TBP-containing factor SL1 represses ribosomal gene transcription, Journal of Molecular Biology, vol.284, issue.1, pp.1-5, 1998.
DOI : 10.1006/jmbi.1998.2164

A. Laferte, E. Favry, A. Sentenac, M. Riva, C. Carles et al., The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components, Genes & Development, vol.20, issue.15, pp.2030-2040, 2006.
DOI : 10.1101/gad.386106

D. L. Lafontaine and D. Tollervey, The function and synthesis of ribosomes, Nature Reviews Molecular Cell Biology, vol.66, issue.7, pp.514-520, 2001.
DOI : 10.1038/35080045

D. Lalo, J. S. Steffan, J. A. Dodd, and M. Nomura, RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I, J Biol Chem, vol.271, pp.21062-21067, 1996.

E. Landrieux, N. Alic, C. Ducrot, J. Acker, M. Riva et al., A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation, The EMBO Journal, vol.25, issue.1, pp.118-128, 2006.
DOI : 10.1038/sj.emboj.7600915

W. H. Lang, B. E. Morrow, Q. Ju, J. R. Warner, and R. H. Reeder, A model for transcription termination by RNA polymerase I, Cell, vol.79, issue.3, pp.527-534, 1994.
DOI : 10.1016/0092-8674(94)90261-5

W. H. Lang and R. H. Reeder, The REB1 site is an essential component of a terminator for RNA polymerase I in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.13, issue.1, pp.649-658, 1993.
DOI : 10.1128/MCB.13.1.649

W. H. Lang and R. H. Reeder, Transcription termination of RNA polymerase I due to a T-rich element interacting with Reb1p., Proceedings of the National Academy of Sciences, vol.92, issue.21, pp.9781-9785, 1995.
DOI : 10.1073/pnas.92.21.9781

G. Langst, T. A. Blank, P. B. Becker, and I. Grummt, RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression, The EMBO Journal, vol.16, issue.4, pp.760-768, 1997.
DOI : 10.1093/emboj/16.4.760

R. M. Learned, S. T. Smale, M. M. Haltiner, and R. Tjian, Regulation of human ribosomal RNA transcription., Proceedings of the National Academy of Sciences, vol.80, issue.12, pp.3558-3562, 1983.
DOI : 10.1073/pnas.80.12.3558

A. Lebedev, K. Scharffetter-kochanek, and S. Iben, Truncated Cockayne Syndrome B Protein Represses Elongation by RNA Polymerase I, Journal of Molecular Biology, vol.382, issue.2, pp.266-274, 2008.
DOI : 10.1016/j.jmb.2008.07.018

A. R. Lehmann, DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy, Biochimie, vol.85, issue.11, pp.1101-1111, 2003.
DOI : 10.1016/j.biochi.2003.09.010

A. K. Leung, D. Gerlich, G. Miller, C. Lyon, Y. W. Lam et al., Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells, The Journal of Cell Biology, vol.104, issue.6, pp.787-800, 2004.
DOI : 10.1083/jcb.129.3.561

Y. Li, R. D. Moir, I. K. Sethy-coraci, J. R. Warner, and I. M. Willis, Repression of Ribosome and tRNA Synthesis in Secretion-Defective Cells Is Signaled by a Novel Branch of the Cell Integrity Pathway, Molecular and Cellular Biology, vol.20, issue.11, pp.3843-3851, 2000.
DOI : 10.1128/MCB.20.11.3843-3851.2000

C. W. Lin, B. Moorefield, J. Payne, P. Aprikian, K. Mitomo et al., A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.16, issue.11, pp.6436-6443, 1996.
DOI : 10.1128/MCB.16.11.6436

R. Loewith, E. Jacinto, S. Wullschleger, A. Lorberg, J. L. Crespo et al., Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control, Molecular Cell, vol.10, issue.3, pp.457-468, 2002.
DOI : 10.1016/S1097-2765(02)00636-6

E. O. Long and I. B. Dawid, Repeated Genes in Eukaryotes, Annual Review of Biochemistry, vol.49, issue.1, pp.727-764, 1980.
DOI : 10.1146/annurev.bi.49.070180.003455

M. S. Longtine, A. R. Mckenzie, D. J. Demarini, N. G. Shah, A. Wach et al., Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae, pp.953-961, 1998.

J. R. Ludwig, S. G. Oliver, and C. S. Mclaughlin, The effect of amino acids on growth and phosphate metabolism in a prototrophic yeast strain, Biochemical and Biophysical Research Communications, vol.79, issue.1, pp.16-23, 1977.
DOI : 10.1016/0006-291X(77)90054-7

N. Mailand, C. Lukas, B. K. Kaiser, P. K. Jackson, J. Bartek et al., Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation, Nature Cell Biology, vol.4, issue.4, pp.317-322, 2002.
DOI : 10.1038/ncb777

P. B. Mason and K. Struhl, Distinction and Relationship between Elongation Rate and Processivity of RNA Polymerase II In Vivo, Molecular Cell, vol.17, issue.6, pp.831-840, 2005.
DOI : 10.1016/j.molcel.2005.02.017

T. Matsuo, Y. Otsubo, J. Urano, F. Tamanoi, and M. Yamamoto, Loss of the TOR Kinase Tor2 Mimics Nitrogen Starvation and Activates the Sexual Development Pathway in Fission Yeast, Molecular and Cellular Biology, vol.27, issue.8, pp.3154-3164, 2007.
DOI : 10.1128/MCB.01039-06

C. Mayer, H. Bierhoff, and I. Grummt, The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis, Genes & Development, vol.19, issue.8, pp.933-941, 2005.
DOI : 10.1101/gad.333205

C. Mayer and I. Grummt, Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases, Oncogene, vol.18, issue.48, pp.6384-6391, 2006.
DOI : 10.1038/sj.onc.1209883

C. Mayer, J. Zhao, X. Yuan, and I. Grummt, mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability, Genes & Development, vol.18, issue.4, pp.423-434, 2004.
DOI : 10.1101/gad.285504

B. Mcstay, M. W. Frazier, and R. H. Reeder, xUBF contains a novel dimerization domain essential for RNA polymerase I transcription., Genes & Development, vol.5, issue.11, pp.1957-1968, 1991.
DOI : 10.1101/gad.5.11.1957

B. Mcstay and I. Grummt, The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology, Annual Review of Cell and Developmental Biology, vol.24, issue.1, pp.131-157, 2008.
DOI : 10.1146/annurev.cellbio.24.110707.175259

T. Melese and Z. Xue, The nucleolus: an organelle formed by the act of building a ribosome, Current Opinion in Cell Biology, vol.7, issue.3, pp.319-324, 1995.
DOI : 10.1016/0955-0674(95)80085-9

K. Merz, M. Hondele, H. Goetze, K. Gmelch, U. Stoeckl et al., Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules, Genes & Development, vol.22, issue.9, pp.1190-1204, 2008.
DOI : 10.1101/gad.466908

P. Milkereit and H. Tschochner, A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription, The EMBO Journal, vol.17, issue.13, pp.3692-3705, 1998.
DOI : 10.1093/emboj/17.13.3692

G. Miller, K. I. Panov, J. K. Friedrich, L. Trinkle-mulcahy, A. I. Lamond et al., hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters, The EMBO Journal, vol.20, issue.6, pp.1373-1382, 2001.
DOI : 10.1093/emboj/20.6.1373

O. L. Miller, . Jr, and B. R. Beatty, Visualization of Nucleolar Genes, Science, vol.164, issue.3882, pp.955-957, 1969.
DOI : 10.1126/science.164.3882.955

K. Mizuta, Regulation of ribosome biosynthesis in Saccharomyces cerevisiae], Tanpakushitsu Kakusan Koso, vol.39, pp.542-549, 1994.

E. B. Mougey, M. O-'reilly, Y. Osheim, O. L. Miller, . Jr et al., The terminal balls characteristic of eukaryotic rRNA transcription units in chromatin spreads are rRNA processing complexes., Genes & Development, vol.7, issue.8, pp.1609-1619, 1993.
DOI : 10.1101/gad.7.8.1609

W. Musters, J. Knol, P. Maas, A. F. Dekker, and H. Van-heerikhuizen, Linker scanning of the yeast RNA polymerase I promoter, Nucleic Acids Research, vol.17, issue.23, pp.9661-9678, 1989.
DOI : 10.1093/nar/17.23.9661

V. Muth, S. Nadaud, I. Grummt, and R. Voit, Acetylation of TAFI68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription, The EMBO Journal, vol.20, issue.6, pp.1353-1362, 2001.
DOI : 10.1093/emboj/20.6.1353

C. R. Nierras and J. R. Warner, Protein Kinase C Enables the Regulatory Circuit That Connects Membrane Synthesis to Ribosome Synthesis in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.274, issue.19, pp.13235-13241, 1999.
DOI : 10.1074/jbc.274.19.13235

Y. Nogi, L. Vu, and M. Nomura, An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae., Proc. Natl. Acad. Sci. USA, pp.7026-7030, 1991.
DOI : 10.1073/pnas.88.16.7026

Y. Nogi, R. Yano, and M. Nomura, Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I., Proc. Natl. Acad. Sci. USA, pp.3962-3966, 1991.
DOI : 10.1073/pnas.88.9.3962

O. Sullivan, A. C. Sullivan, G. J. Mcstay, and B. , UBF Binding In Vivo Is Not Restricted to Regulatory Sequences within the Vertebrate Ribosomal DNA Repeat, Molecular and Cellular Biology, vol.22, issue.2, pp.657-668, 2002.
DOI : 10.1128/MCB.22.2.657-668.2002

M. Oakes, Y. Nogi, M. W. Clark, and M. Nomura, Structural alterations of the nucleolus in mutants of Saccharomyces cerevisiae defective in RNA polymerase I., Molecular and Cellular Biology, vol.13, issue.4, pp.2441-2455, 1993.
DOI : 10.1128/MCB.13.4.2441

M. Oakes, I. Siddiqi, L. Vu, J. Aris, and M. Nomura, Transcription Factor UAF, Expansion and Contraction of Ribosomal DNA (rDNA) Repeats, and RNA Polymerase Switch in Transcription of Yeast rDNA, Molecular and Cellular Biology, vol.19, issue.12, pp.8559-8569, 1999.
DOI : 10.1128/MCB.19.12.8559

M. L. Oakes, I. Siddiqi, S. L. French, L. Vu, M. Sato et al., Role of Histone Deacetylase Rpd3 in Regulating rRNA Gene Transcription and Nucleolar Structure in Yeast, Molecular and Cellular Biology, vol.26, issue.10, pp.3889-3901, 2006.
DOI : 10.1128/MCB.26.10.3889-3901.2006

R. L. Ochs, M. A. Lischwe, W. H. Spohn, and H. Busch, Fibrillarin: a new protein of the nucleolus identified by autoimmune sera, Biology of the Cell, vol.54, issue.2, pp.123-133, 1985.
DOI : 10.1111/j.1768-322X.1985.tb00387.x

S. G. Oliver, From gene to screen with yeast, Current Opinion in Genetics & Development, vol.7, issue.3, pp.405-409, 1997.
DOI : 10.1016/S0959-437X(97)80156-6

S. G. Oliver and C. S. Mclaughlin, The regulation of RNA synthesis in yeast I: Starvation experiments, MGG Molecular & General Genetics, vol.68, issue.2, pp.145-153, 1977.
DOI : 10.1007/BF00330830

Y. N. Osheim, S. L. French, K. M. Keck, E. A. Champion, K. Spasov et al., Pre-18S Ribosomal RNA Is Structurally Compacted into the SSU Processome Prior to Being Cleaved from Nascent Transcripts in Saccharomyces cerevisiae, Molecular Cell, vol.16, issue.6, pp.943-954, 2004.
DOI : 10.1016/j.molcel.2004.11.031

K. I. Panov, J. K. Friedrich, J. Russell, and J. C. Zomerdijk, UBF activates RNA polymerase I transcription by stimulating promoter escape, The EMBO Journal, vol.266, issue.14, pp.3310-3322, 2006.
DOI : 10.1038/sj.emboj.7601221

K. I. Panov, J. K. Friedrich, and J. C. Zomerdijk, A Step Subsequent to Preinitiation Complex Assembly at the Ribosomal RNA Gene Promoter Is Rate Limiting for Human RNA Polymerase I-Dependent Transcription, Molecular and Cellular Biology, vol.21, issue.8, pp.2641-2649, 2001.
DOI : 10.1128/MCB.21.8.2641-2649.2001

T. Pederson, The plurifunctional nucleolus, Nucleic Acids Research, vol.26, issue.17, pp.3871-3876, 1998.
DOI : 10.1093/nar/26.17.3871

A. F. Pendle, G. P. Clark, R. Boon, D. Lewandowska, Y. W. Lam et al., Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel Nucleolar Functions, Molecular Biology of the Cell, vol.16, issue.1, pp.260-269, 2005.
DOI : 10.1091/mbc.E04-09-0791

G. Peyroche, P. Milkereit, N. Bischler, H. Tschochner, P. Schultz et al., The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3, The EMBO Journal, vol.19, issue.20, pp.5473-5482, 2000.
DOI : 10.1093/emboj/19.20.5473

T. Powers and P. Walter, Regulation of Ribosome Biogenesis by the Rapamycin-sensitive TOR-signaling Pathway in Saccharomyces cerevisiae, Molecular Biology of the Cell, vol.10, issue.4, pp.987-1000, 1999.
DOI : 10.1091/mbc.10.4.987

T. Preiss, J. Baron-benhamou, W. Ansorge, and M. W. Hentze, Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock, Nature Structural Biology, vol.10, issue.12, pp.1039-1047, 2003.
DOI : 10.1038/nsb1015

E. M. Prescott, Y. N. Osheim, H. S. Jones, C. M. Alen, J. G. Roan et al., Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p, Proceedings of the National Academy of Sciences, vol.101, issue.16, pp.6068-6073, 2004.
DOI : 10.1073/pnas.0401393101

F. Puvion-dutilleul, S. Mazan, M. Nicoloso, M. E. Christensen, and J. P. Bachellerie, Localization of U3 RNA molecules in nucleoli of HeLa and mouse 3T3 cells by high resolution in situ hybridization, Eur J Cell Biol, vol.56, pp.178-186, 1991.

S. Pyronnet and N. Sonenberg, Cell-cycle-dependent translational control, Current Opinion in Genetics & Development, vol.11, issue.1, pp.13-18, 2001.
DOI : 10.1016/S0959-437X(00)00150-7

R. H. Reeder, Regulation of RNA Polymerase I Transcription in Yeast and Vertebrates, Prog Nucleic Acid Res Mol Biol, vol.62, pp.293-327, 1999.
DOI : 10.1016/S0079-6603(08)60511-5

R. H. Reeder, P. Guevara, and J. G. Roan, RNA Polymerase I Terminates Transcription at the Reb1 Terminator In Vivo, Molecular and Cellular Biology, vol.19, issue.11, pp.7369-7376, 1999.
DOI : 10.1128/MCB.19.11.7369

R. H. Reeder and W. H. Lang, Terminating transcription in eukaryotes: lessons learned from RNA polymerase I, Trends in Biochemical Sciences, vol.22, issue.12, pp.473-477, 1997.
DOI : 10.1016/S0968-0004(97)01133-X

R. G. Roeder and W. J. Rutter, Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms, Nature, vol.154, issue.5216, pp.234-237, 1969.
DOI : 10.1016/0006-291X(68)90316-1

S. O. Rogers, G. C. Beaulieu, and A. J. Bendich, [18] Comparative studies of gene copy number, Methods Enzymol, vol.224, pp.243-251, 1993.
DOI : 10.1016/0076-6879(93)24019-Q

J. R. Rohde, R. Bastidas, R. Puria, and M. E. Cardenas, Nutritional control via Tor signaling in Saccharomyces cerevisiae, Current Opinion in Microbiology, vol.11, issue.2, pp.153-160, 2008.
DOI : 10.1016/j.mib.2008.02.013

A. G. Rondon, M. Garcia-rubio, S. Gonzalez-barrera, and A. Aguilera, Molecular evidence for a positive role of Spt4 in transcription elongation, The EMBO Journal, vol.22, issue.3, pp.612-620, 2003.
DOI : 10.1093/emboj/cdg047

I. B. Rosenwald, Deregulation of protein synthesis as a mechanism of neoplastic transformation, BioEssays, vol.14, issue.3, pp.243-250, 1996.
DOI : 10.1002/bies.950180312

P. Roussel, C. Andre, L. Comai, and D. Hernandez-verdun, The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs, The Journal of Cell Biology, vol.133, issue.2, pp.235-246, 1996.
DOI : 10.1083/jcb.133.2.235

D. Rudra and J. R. Warner, What better measure than ribosome synthesis?, Genes & Development, vol.18, issue.20, pp.2431-2436, 2004.
DOI : 10.1101/gad.1256704

URL : http://www.genesdev.org/cgi/content/short/18/20/2431

D. Ruggero and P. P. Pandolfi, Does the ribosome translate cancer?, Nature Reviews Cancer, vol.4, issue.3, pp.179-192, 2003.
DOI : 10.1038/nrc1015

E. P. Rustchenko, T. M. Curran, and F. Sherman, Variations in the number of ribosomal DNA units in morphological mutants and normal strains of Candida albicans and in normal strains of Saccharomyces cerevisiae., Journal of Bacteriology, vol.175, issue.22, pp.7189-7199, 1993.
DOI : 10.1128/jb.175.22.7189-7199.1993

J. J. Sandmeier, S. French, Y. Osheim, W. L. Cheung, C. M. Gallo et al., RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase, The EMBO Journal, vol.21, issue.18, pp.4959-4968, 2002.
DOI : 10.1093/emboj/cdf498

D. D. Sarbassov, S. M. Ali, S. Sengupta, J. H. Sheen, P. P. Hsu et al., Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB, Molecular Cell, vol.22, issue.2, pp.159-168, 2006.
DOI : 10.1016/j.molcel.2006.03.029

URL : http://doi.org/10.1016/j.molcel.2006.03.029

T. Schimmang, D. Tollervey, H. Kern, R. Frank, and E. C. Hurt, A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability, EMBO J, vol.8, pp.4015-4024, 1989.

T. Schmelzle and M. N. Hall, TOR, a Central Controller of Cell Growth, Cell, vol.103, issue.2, pp.253-262, 2000.
DOI : 10.1016/S0092-8674(00)00117-3

A. Schmidt, M. Bickle, T. Beck, and M. N. Hall, The Yeast Phosphatidylinositol Kinase Homolog TOR2 Activates RHO1 and RHO2 via the Exchange Factor ROM2, Cell, vol.88, issue.4, pp.531-542, 1997.
DOI : 10.1016/S0092-8674(00)81893-0

A. Schnapp and I. Grummt, Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I, J. Biol. Chem, vol.266, pp.24588-24595, 1991.

D. A. Schneider, S. L. French, Y. N. Osheim, A. O. Bailey, L. Vu et al., RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing, Proceedings of the National Academy of Sciences, vol.103, issue.34, pp.12707-12712, 2006.
DOI : 10.1073/pnas.0605686103

D. A. Schneider, A. Michel, M. L. Sikes, L. Vu, J. A. Dodd et al., Transcription Elongation by RNA Polymerase I Is Linked to Efficient rRNA Processing and Ribosome Assembly, Molecular Cell, vol.26, issue.2, pp.217-229, 2007.
DOI : 10.1016/j.molcel.2007.04.007

S. N. Sehgal, H. Baker, and C. Vezina, Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization., The Journal of Antibiotics, vol.28, issue.10, pp.727-732, 1975.
DOI : 10.7164/antibiotics.28.727

A. F. Shamji, F. G. Kuruvilla, and S. L. Schreiber, Partitioning the transcriptional program induced by rapamycin among the effectors of the Tor proteins, Current Biology, vol.10, issue.24, pp.1574-1581, 2000.
DOI : 10.1016/S0960-9822(00)00866-6

W. Shou, J. H. Seol, A. Shevchenko, C. Baskerville, D. Moazed et al., Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex, Cell, vol.97, issue.2, pp.233-244, 1999.
DOI : 10.1016/S0092-8674(00)80733-3

V. Sirri, D. Hernandez-verdun, and P. Roussel, Cyclin-dependent kinases govern formation and maintenance of the nucleolus, The Journal of Cell Biology, vol.73, issue.6, pp.969-981, 2002.
DOI : 10.1091/mbc.9.2.437

V. Sirri, P. Roussel, and D. Hernandez-verdun, In Vivo Release of Mitotic Silencing of Ribosomal Gene Transcription Does Not Give Rise to Precursor Ribosomal RNA Processing, The Journal of Cell Biology, vol.34, issue.2, pp.259-270, 2000.
DOI : 10.1007/BF00352307

V. Sirri, S. Urcuqui-inchima, P. Roussel, and D. Hernandez-verdun, Nucleolus: the fascinating nuclear body, Histochemistry and Cell Biology, vol.266, issue.1, pp.13-31, 2008.
DOI : 10.1007/s00418-007-0359-6

URL : https://hal.archives-ouvertes.fr/hal-00195457

V. Stefanovsky, F. Langlois, T. Gagnon-kugler, L. I. Rothblum, and T. Moss, Growth Factor Signaling Regulates Elongation of RNA Polymerase I Transcription in Mammals via UBF Phosphorylation and r-Chromatin Remodeling, Molecular Cell, vol.21, issue.5, pp.629-639, 2006.
DOI : 10.1016/j.molcel.2006.01.023

V. Y. Stefanovsky and T. Moss, The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation, Nucleic Acids Research, vol.36, issue.15, pp.5093-5101, 2008.
DOI : 10.1093/nar/gkn484

V. Y. Stefanovsky, G. Pelletier, D. P. Bazett-jones, C. Crane-robinson, and T. Moss, DNA looping in the RNA polymerase I enhancesome is the result of non-cooperative in-phase bending by two UBF molecules, Nucleic Acids Research, vol.29, issue.15, pp.3241-3247, 2001.
DOI : 10.1093/nar/29.15.3241

V. Y. Stefanovsky, G. Pelletier, R. Hannan, T. Gagnon-kugler, L. I. Rothblum et al., An Immediate Response of Ribosomal Transcription to Growth Factor Stimulation in Mammals Is Mediated by ERK Phosphorylation of UBF, Molecular Cell, vol.8, issue.5, pp.1063-1073, 2001.
DOI : 10.1016/S1097-2765(01)00384-7

J. Steffan, D. Keys, J. Dodd, and M. Nomura, The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor., Genes & Development, vol.10, issue.20, pp.2551-2563, 1996.
DOI : 10.1101/gad.10.20.2551

L. A. Stolinski, D. M. Eisenmann, and K. M. Arndt, Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.17, issue.8, pp.4490-4500, 1997.
DOI : 10.1128/MCB.17.8.4490

M. Sullivan, T. Higuchi, V. L. Katis, and F. Uhlmann, Cdc14 Phosphatase Induces rDNA Condensation and Resolves Cohesin-Independent Cohesion during Budding Yeast Anaphase, Cell, vol.117, issue.4, pp.471-482, 2004.
DOI : 10.1016/S0092-8674(04)00415-5

URL : http://doi.org/10.1016/s0092-8674(04)00415-5

M. Thiry and D. L. Lafontaine, Birth of a nucleolus: the evolution of nucleolar compartments, Trends in Cell Biology, vol.15, issue.4, pp.194-199, 2005.
DOI : 10.1016/j.tcb.2005.02.007

M. J. Thomas, A. A. Platas, and D. K. Hawley, Transcriptional Fidelity and Proofreading by RNA Polymerase II, Cell, vol.93, issue.4, pp.627-637, 1998.
DOI : 10.1016/S0092-8674(00)81191-5

URL : http://doi.org/10.1016/s0092-8674(00)81191-5

D. Tollervey, H. Lehtonen, M. Carmo-fonseca, and C. E. Hurt, The small nucleolar RNP protein NOP1 (fibrillarin) is required for pre-rRNA processing in yeast, EMBO J, vol.10, pp.573-583, 1991.

J. Torres-rosell, F. Machin, A. Jarmuz, and L. Aragon, Nucleolar Segregation Lags Behind the Rest of the Genome and Requires Cdc14p Activation by the FEAR Network, Cell Cycle, vol.3, issue.4, pp.496-502, 2004.
DOI : 10.4161/cc.3.4.802

S. Trumtel, I. Leger-silvestre, P. E. Gleizes, F. Teulieres, and N. Gas, Assembly and Functional Organization of the Nucleolus: Ultrastructural Analysis of Saccharomyces cerevisiae Mutants, Molecular Biology of the Cell, vol.11, issue.6, pp.2175-2189, 2000.
DOI : 10.1091/mbc.11.6.2175

C. K. Tsang, P. G. Bertram, W. Ai, R. Drenan, and X. F. Zheng, Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR, The EMBO Journal, vol.89, issue.22, pp.6045-6056, 2003.
DOI : 10.1093/emboj/cdg578

C. K. Tsang and X. F. Zheng, TOR-in(g) the Nucleus, Cell Cycle, vol.6, issue.1, pp.25-29, 2007.
DOI : 10.4161/cc.6.1.3675

H. Tschochner and E. Hurt, Pre-ribosomes on the road from the nucleolus to the cytoplasm, Trends in Cell Biology, vol.13, issue.5, pp.255-263, 2003.
DOI : 10.1016/S0962-8924(03)00054-0

H. Tschochner and P. Milkereit, depends on an additional factor to release terminated transcripts from the template, FEBS Letters, vol.14, issue.2-3, pp.461-466, 1997.
DOI : 10.1016/S0014-5793(97)00636-4

M. Vogelauer, F. Cioci, and G. Camilloni, DNA protein-interactions at the Saccharomyces cerevisiae 35 S rRNA promoter and in its surrounding region, Journal of Molecular Biology, vol.275, issue.2, pp.197-209, 1998.
DOI : 10.1006/jmbi.1997.1451

R. Voit, K. Schafer, and I. Grummt, Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein., Molecular and Cellular Biology, vol.17, issue.8, pp.4230-4237, 1997.
DOI : 10.1128/MCB.17.8.4230

H. Wai, K. Johzuka, L. Vu, K. Eliason, T. Kobayashi et al., Yeast RNA Polymerase I Enhancer Is Dispensable for Transcription of the Chromosomal rRNA Gene and Cell Growth, and Its Apparent Transcription Enhancement from Ectopic Promoters Requires Fob1 Protein, Molecular and Cellular Biology, vol.21, issue.16, pp.5541-5553, 2001.
DOI : 10.1128/MCB.21.16.5541-5553.2001

C. Waldron, Synthesis of Ribosomal and Transfer Ribonucleic Acids in Yeast During a Nutritional Shift-up, Journal of General Microbiology, vol.98, issue.1, pp.215-221, 1977.
DOI : 10.1099/00221287-98-1-215

C. Waldron and F. Lacroute, Effect of growth rate on the amounts of ribosomal and transfer ribonucleic acids in yeast, J. Bacteriol, vol.122, pp.855-865, 1975.

P. Walter and A. E. Johnson, Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane, Annual Review of Cell Biology, vol.10, issue.1, pp.87-119, 1994.
DOI : 10.1146/annurev.cb.10.110194.000511

A. T. Wierzbicki, J. R. Haag, and C. S. Pikaard, Noncoding Transcription by RNA Polymerase Pol IVb/Pol V Mediates Transcriptional Silencing of Overlapping and Adjacent Genes, Cell, vol.135, issue.4, pp.635-648, 2008.
DOI : 10.1016/j.cell.2008.09.035

S. Wullschleger, R. Loewith, and M. N. Hall, TOR Signaling in Growth and Metabolism, Cell, vol.124, issue.3, pp.471-484, 2006.
DOI : 10.1016/j.cell.2006.01.016

W. Xie and L. I. Rothblum, Domains of the rat rDNA promoter must be aligned stereospecifically., Molecular and Cellular Biology, vol.12, issue.3, pp.1266-1275, 1992.
DOI : 10.1128/MCB.12.3.1266

R. T. Yamamoto, Y. Nogi, J. A. Dodd, and M. Nomura, RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template, Embo J, vol.15, pp.3964-3973, 1996.

X. Yuan, W. Feng, A. Imhof, I. Grummt, and Y. Zhou, Activation of RNA Polymerase I Transcription by Cockayne Syndrome Group B Protein and Histone Methyltransferase G9a, Molecular Cell, vol.27, issue.4, pp.585-595, 2007.
DOI : 10.1016/j.molcel.2007.06.021

X. Yuan, J. Zhao, H. Zentgraf, U. Hoffmann-rohrer, and I. Grummt, Multiple interactions between RNA polymerase I, TIF-IA and TAFI subunits regulate preinitiation complex assembly at the ribosomal gene promoter, EMBO reports, vol.3, issue.11, pp.1082-1087, 2002.
DOI : 10.1093/embo-reports/kvf212

M. M. Yusupov, G. Z. Yusupova, A. Baucom, K. Lieberman, T. N. Earnest et al., Crystal Structure of the Ribosome at 5.5 A Resolution, Science, vol.292, issue.5518, pp.883-896, 2001.
DOI : 10.1126/science.1060089

D. Zaragoza, A. Ghavidel, J. Heitman, and M. C. Schultz, Program of Transcriptional Repression in Yeast by Interfering with the TOR Signaling Pathway, Molecular and Cellular Biology, vol.18, issue.8, pp.4463-4470, 1998.
DOI : 10.1128/MCB.18.8.4463

W. Zhai and L. Comai, Repression of RNA Polymerase I Transcription by the Tumor Suppressor p53, Molecular and Cellular Biology, vol.20, issue.16, pp.5930-5938, 2000.
DOI : 10.1128/MCB.20.16.5930-5938.2000

Y. Zhang, M. L. Sikes, A. L. Beyer, and D. A. Schneider, The Paf1 complex is required for efficient transcription elongation by RNA polymerase I, Proceedings of the National Academy of Sciences, vol.106, issue.7, pp.2153-2158, 2009.
DOI : 10.1073/pnas.0812939106

J. Zhao, X. Yuan, M. Frodin, and I. Grummt, ERK-Dependent Phosphorylation of the Transcription Initiation Factor TIF-IA Is Required for RNA Polymerase I Transcription and Cell Growth, Molecular Cell, vol.11, issue.2, pp.405-413, 2003.
DOI : 10.1016/S1097-2765(03)00036-4

S. Zhong, C. Zhang, and D. L. Johnson, Epidermal Growth Factor Enhances Cellular TATA Binding Protein Levels and Induces RNA Polymerase I- and III-Dependent Gene Activity, Molecular and Cellular Biology, vol.24, issue.12, pp.5119-5129, 2004.
DOI : 10.1128/MCB.24.12.5119-5129.2004