Skip to Main content Skip to Navigation
Theses

apoptose et homéostasie des lymphocytes T producteurs de cytokines: altérations au cours de l'infection chronique par le VIH et de son traitement

Abstract : This work suggests that increased apoptosis limits the virus-driven expansion of TNFa T cells during untreated infection, but that the rapid suppression of apoptosis following antiretroviral therapy favours a pro-inflammatory polarisation of T cells, which could be a risk factor for metabolic and inflammatory side-effects associated to immune restoration.
Document type :
Theses
Complete list of metadatas

https://tel.archives-ouvertes.fr/tel-00411274
Contributor : Eric Ledru <>
Submitted on : Wednesday, August 26, 2009 - 5:54:47 PM
Last modification on : Wednesday, December 9, 2020 - 3:12:28 PM
Long-term archiving on: : Tuesday, June 15, 2010 - 9:06:35 PM

Identifiers

  • HAL Id : tel-00411274, version 1

Citation

Eric Ledru. apoptose et homéostasie des lymphocytes T producteurs de cytokines: altérations au cours de l'infection chronique par le VIH et de son traitement. Immunologie. Université Pierre et Marie Curie - Paris VI, 2002. Français. ⟨tel-00411274⟩

Share

Metrics

Record views

446

Files downloads

177