G. Leggio, L. Addolorato, G. Abenaroli, and . Gasbarrini, Wilson's Disease: Clinical, Genetic and Pharmacological Findings, International Journal of Immunopathology and Pharmacology, vol.17, issue.1, p.7, 2005.
DOI : 10.1177/039463200501800102

C. Carter and J. X. Ho, Structure of Serum Albumin, Adv. Protein. Chem, vol.45, p.153, 1994.
DOI : 10.1016/S0065-3233(08)60640-3

X. M. He and D. C. Carter, Atomic structure and chemistry of human serum albumin, Nature, vol.358, issue.6383, p.209, 1992.
DOI : 10.1038/358209a0

T. Peters and J. , Serum Albumin, Prot. Chem, vol.37, p.161, 1985.
DOI : 10.1016/S0065-3233(08)60065-0

U. Patel, P. J. Sadler, A. Tucker, and J. H. Viles, Direct detection of albumin in human blood plasma by proton NMR spectroscopy. Complexation of nickel2+, Journal of the American Chemical Society, vol.115, issue.20, p.9285, 1993.
DOI : 10.1021/ja00073a053

W. Kozlowski, M. Bal, T. Dyba, and . Kowalik-jankowska, Specific structure???stability relations in metallopeptides, Coordination Chemistry Reviews, vol.184, issue.1, p.319, 1999.
DOI : 10.1016/S0010-8545(98)00261-6

J. Bal, P. J. Christodoulou, A. Sadler, J. Tucker, S. Zhang et al., Multi-metal binding site of serum albumin, Journal of Inorganic Biochemistry, vol.70, issue.1, pp.33-3057, 1998.
DOI : 10.1016/S0162-0134(98)00010-5

M. Sokolowska, A. Krezel, M. Dyba, Z. Szewczuk, and W. Bal, Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin, European Journal of Biochemistry, vol.19, issue.4, p.1323, 2002.
DOI : 10.1046/j.1432-1033.2002.02772.x

N. Hanaki, J. Ikota, T. Ueda, A. Ozawa, and . Odani, Transport of the Cu(II) Bound with Histidine-Containing Tripeptides to Cysteine. Coordination Mode and Exchangeability of Cu(II) in the Complexes, Bulletin of the Chemical Society of Japan, vol.76, issue.11, p.2143, 2003.
DOI : 10.1246/bcsj.76.2143

M. C. Orfei, G. Alcaro, M. Marcon, M. Chelli, H. Ginanneschi et al., Modeling of copper(II) sites in proteins based on histidyl and glycyl residues, Journal of Inorganic Biochemistry, vol.97, issue.3, p.299, 2003.
DOI : 10.1016/S0162-0134(03)00283-6

D. N. Brotman, L. Flancbaum, Y. E. Kang, G. F. Merril, and H. Ficher, Positive inotropic effect of carcinine in the isolated perfused guinea pig heart, Critical Care Medicine, vol.18, issue.3, p.317, 1990.
DOI : 10.1097/00003246-199003000-00015

M. Tsuji, Y. Matsuoka, T. L. Nakajima-)-k, P. D. Reichelt, E. Edminson et al., STUDIES ON FORMATION OF ?-GLUTAMYLAMINES IN RAT BRAIN AND THEIR SYNTHETIC AND CATABOLIC ENZYMES, Journal of Neurochemistry, vol.250, issue.4, pp.633-811, 1976.
DOI : 10.1016/S0021-9673(01)92327-1

D. N. Flancbaum, J. C. Brotman, T. Fitzpatrick, E. Van-es, H. Kasziba et al., Existence of carcinine, a histamine-related compound, in mammalian tissues, Life Sciences, vol.47, issue.17, p.1587, 1990.
DOI : 10.1016/0024-3205(90)90188-W

B. Gajda, A. Henry, J. J. Aubry, and . Delpuech, Proton and Metal Ion Interactions with Glycylglycylhistamine, a Serum Albumin Mimicking Pseudopeptide, Inorganic Chemistry, vol.35, issue.3, p.586, 1996.
DOI : 10.1021/ic950373e

B. Gizzi, P. Henry, S. Rubini, E. Giroux, and . Wenger, A multi-approach study of the interaction of the Cu(II) and Ni(II) ions with alanylglycylhistamine, a mimicking pseudopeptide of the serum albumine N-terminal residue, Journal of Inorganic Biochemistry, vol.99, issue.5, p.1182, 2005.
DOI : 10.1016/j.jinorgbio.2005.02.018
URL : https://hal.archives-ouvertes.fr/hal-00089584

C. Auberger, L. Gérardin, C. Rodehuser, C. Finance, L. Nicolazzi et al., New biosurfactants containing ??-lactam and triazole rings, Progr. Colloid Polym. Sci, vol.118, p.145, 2001.
DOI : 10.1007/3-540-45725-9_33

M. S. Ozer, C. Gérardin-charbonnier, S. Thiébaut, L. Rodehuser, and C. Selve, Synthesis of perfluoroalkylated?-alanine and some peptide derivatives: An access to original surfactants, Amino Acids, vol.82, issue.22, pp.381-551, 1995.
DOI : 10.1007/BF01388177

. Merck, Méthodes d'analyses complexométriques par les Titriplex ® , Merck, Darmstadt (46) E. Högfeldt, Stability constants of metal-ion complexes, Part A inorganic ligands, p.32, 1982.

I. Zekani, Computational methods for the determination of stability constants, edition D.Legget, 50) G.M. Sheldrick, "SHELX97" et "SHELXL97 Program for crystal structure determination, 1985.

D. Mineo, D. L. Vitalini, E. Mendola, E. Rizzarelli, G. Scamparino et al., Electrospray mass spectrometric studies ofL-carnosine (?-alanyl-L-histidine) complexes with copper(II) or zinc ions in aqueous solution, Rapid Communications in Mass Spectrometry, vol.57, issue.7, p.722, 2002.
DOI : 10.1002/rcm.633

H. Lavanant, Y. Virelizier, and J. Hopilliard, Reduction of copper(II) complexes by electron capture in an electrospray ionization source, Journal of the American Society for Mass Spectrometry, vol.32, issue.11, p.1217, 1998.
DOI : 10.1016/S1044-0305(98)00100-7

A. Decker, V. Ivanov, B. Z. Zhu, and B. Frei, Inhibition of Low-Density Lipoprotein Oxidation by Carnosine and Histidine, Journal of Agricultural and Food Chemistry, vol.49, issue.1, p.511, 2001.
DOI : 10.1021/jf0010533

W. Lee, H. Miyawaki, E. Bobst, J. D. Hester, M. Ashraf et al., Improved Functional Recovery of Ischemic Rat Hearts due to Singlet Oxygen Scavengers Histidine and Carnosine, Journal of Molecular and Cellular Cardiology, vol.31, issue.1, p.113, 1999.
DOI : 10.1006/jmcc.1998.0850

J. H. Kang and W. S. Eum, Enhanced oxidative damage by the familial amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutants, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1524, issue.2-3, p.162, 2000.
DOI : 10.1016/S0304-4165(00)00153-7

C. Hamdoune, L. Moujahid, C. Rodehüser, B. Gérardin, M. J. Henry et al., Amphiphilic and cation-complexing compounds based on peptidoamines, New Journal of Chemistry, vol.24, issue.12, p.1037, 2000.
DOI : 10.1039/b006739n

L. Perchec, Les molécules de la beauté, de l'hygiène et de la protection, CNRS Éditions Nathan, 1994.

I. Malgesini, R. Verpilio, P. Duncan, and . Feruti, Poly(amido-amine)s Carrying Primary Amino Groups as Side Substituents, Macromolecular Bioscience, vol.9, issue.1, p.59, 2003.
DOI : 10.1002/mabi.200390009

W. Fuerstenau and R. Herrera-urbina, Surfactants Science Series -Cationic Surfactants, p.415, 1991.

W. Smith, Reagents in mineral technology

C. Fuguet, M. Rafois, E. Roses, and . Bosch, Critical micelle concentration of surfactants in aqueous buffered and unbuffered systems, Analytica Chimica Acta, vol.548, issue.1-2, p.95, 2005.
DOI : 10.1016/j.aca.2005.05.069

B. Thevenot, G. Grassi, W. Bastiat, and . Binana, Colloids surf, J. Am. Chem. Soc, vol.252, issue.99, p.2039, 1997.

C. Yan, C. Jin, J. Wang, J. X. Ye, . G. Xiao-)-r et al., Surfactants Science Series -Cationic Surfactants, J. Colloid Interface Sci, vol.288, issue.37, p.13, 1991.

C. W. Xing, K. H. Yu, P. L. Chow, D. Ho, B. Fu et al., Hydrophobic Interaction and Hydrogen Bonding Cooperatively Confer a Vancomycin Hydrogel:?? A Potential Candidate for Biomaterials, Journal of the American Chemical Society, vol.124, issue.50, p.14846, 2002.
DOI : 10.1021/ja028539f

K. Kiyonaka, S. Sugiyasu, I. Shinkai, and . Hamachi, First Thermally Responsive Supramolecular Polymer Based on Glycosylated Amino Acid, Journal of the American Chemical Society, vol.124, issue.37, p.10954, 2002.
DOI : 10.1021/ja027277e

N. Imae, T. Hayashi, T. Matsumoto, M. Tada, and . Furusaka, Structures of Fibrous Supramolecular Assemblies Constructed by Amino Acid Surfactants: Investigation by AFM, SANS, and SAXS, Journal of Colloid and Interface Science, vol.225, issue.2, pp.285-363, 1994.
DOI : 10.1006/jcis.2000.6763

Z. Szakács, M. Kraszni, and B. , Determination of microscopic acid?base parameters from NMR?pH titrations, Analytical and Bioanalytical Chemistry, vol.378, issue.6, pp.1428-1476, 2002.
DOI : 10.1007/s00216-003-2390-3

. Serratrice, Thèse obtenue à l'université Henri Poincaré, 1971.

J. Chrisment, J. J. Delpuech-)-e, and . Milner-white, RMN 1 H (400 MHz, MeOD) : 0,94 ppm (t, 3 J = 6,5 Hz, 3H, CH 3 a), Langmuir J. Mol. Biol, vol.12, issue.4, pp.1441-3852, 1990.

. Hydrochlorure-de-décanoate, RMN 1 H (400 MHz, MeOD) : 0,90 ppm (t, 3 J = 6,5 Hz, 3H, CH 3 a), pp.62-96

1. Hz, 1. , and 1. , ), pp.37-61

. Dans-un-ballon, mmoles de BOC-histidine (2 g) sont dissoutes dans 50 mL d'acétonitrile, sous agitation magnétique, p.45, 2008.

. Dihydrochlorure, RMN 1 H (400 MHz, MeOD) : 0,92 ppm (t, 3 J = 6,5 Hz, 3H, CH 3 a) b) ; 1,62 ppm (m, 2H, CH 2 c), pp.24-72

. Hz, 57 ppm (t, 3 J = 5 Hz, CH 2 f), pp.70-100

. Ppm, 6 ppm (CH 2 e), CH i, vol.42, issue.66, pp.2-7

. Dans-un-ballon-de, eau froide, 320 mmoles d'(éthylènedioxy)biséthylamine sont dissoutes dans 200 ml de CHCl 3 sous agitation. Puis sont ajoutées pendant une heure et par portion, mmoles de chlorure de triphenylméthyle en maintenant la température du bain entre 5 et 10 °C. Le mélange est agité jusqu'à ce que la température remonte à l'ambiante. Le mélange est ensuite lavé par 200 mL de solution saturée de NaCl

. Rendement, SiO 2 ; AcOEt) : Rf = 0, p.57

. Le-protocole-est-identique-À-celui-de-la-synthèse-des-composés-gly, La BOCglycine remplace la BOC-glycyl-glycine. Après filtration et séchage du produit de couplage qui précipite, on obtient un solide blanc qui est ensuite recristallisé dans l'acétonitrile. Le solide recristallisé est dispersé dans l'éther anhydre et soumis à un courant d'HCl gazeux

2. Hz, CH 2 n) ; 3.75 ppm (m, 4H, p.84