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Les modes normaux de basse fréquence des protéines

Abstract : Low-frequency normal modes often give useful information on the large-amplitude functional motions of proteins, as determined experimentally using, e.g., X-ray cristallography. This result seems to be quite robust, since it has been obtained using atomic-level description of proteins, as well as coarse-grained ones. Building upon this result, several applications have been proposed, in particular in the field of structural refinement. This text is a review of what has been achieved to date, with a particular emphasis on my own contributions. Among the most recent developments, attempts to complexify current elastic network models, by adding nonlinear terms, are evoked.
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Contributor : Yves-Henri Sanejouand <>
Submitted on : Monday, February 25, 2008 - 12:30:59 PM
Last modification on : Wednesday, November 20, 2019 - 3:13:49 AM
Long-term archiving on: : Thursday, May 20, 2010 - 7:36:14 PM


  • HAL Id : tel-00258781, version 1



Yves-Henri Sanejouand. Les modes normaux de basse fréquence des protéines. Biophysique []. Université Claude Bernard - Lyon I, 2007. ⟨tel-00258781⟩



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