J. P. Abrahams, A. G. Leslie, R. Lutter, and J. E. Walker, Structure at 2.8 ?? resolution of F1-ATPase from bovine heart mitochondria, Nature, vol.370, issue.6491, pp.621-628, 1994.
DOI : 10.1038/370621a0

A. Allali-hassani, T. L. Campbell, A. Ho, J. W. Schertzer, and E. D. Brown, protein of unknown function, Biochemical Journal, vol.384, issue.3, pp.577-584, 2004.
DOI : 10.1042/BJ20041082

L. Aravind, V. M. Dixit, and E. V. Koonin, The domains of death: evolution of the apoptosis machinery, Trends in Biochemical Sciences, vol.24, issue.2, pp.47-53, 1999.
DOI : 10.1016/S0968-0004(98)01341-3

M. Arifuzzaman, M. Maeda, A. Itoh, K. Nishikata, C. Takita et al., Large-scale identification of protein-protein interaction of Escherichia coli K-12, Genome Research, vol.16, issue.5, pp.686-691, 2006.
DOI : 10.1101/gr.4527806

V. Benard and G. M. Bokoch, Assay of Cdc42, Rac, and Rho GTPase Activation by Affinity Methods, Methods Enzymol, vol.345, pp.349-359, 2002.
DOI : 10.1016/S0076-6879(02)45028-8

H. Berchtold, L. Reshetnikova, C. O. Reiser, N. K. Schirmer, M. Sprinzl et al., Crystal structure of active elongation factor Tu reveals major domain rearrangements, Nature, vol.365, issue.6442, pp.126-132, 1993.
DOI : 10.1038/365126a0

S. Betts, M. Speed, and J. King, [22] Detection of early aggregation intermediates by native gel electrophoresis and native Western blotting, Methods Enzymol, vol.309, pp.333-350, 1999.
DOI : 10.1016/S0076-6879(99)09024-2

A. P. Bhavsar, X. Zhao, and E. D. Brown, Development and Characterization of a Xylose-Dependent System for Expression of Cloned Genes in Bacillus subtilis: Conditional Complementation of a Teichoic Acid Mutant, Applied and Environmental Microbiology, vol.67, issue.1, pp.403-410, 2001.
DOI : 10.1128/AEM.67.1.403-410.2001

H. C. Birnboim and J. Doly, A rapid alkaline extraction procedure for screening recombinant plasmid DNA, Nucleic Acids Research, vol.7, issue.6, pp.1513-1523, 1979.
DOI : 10.1093/nar/7.6.1513

D. Brochu and C. Vadeboncoeur, The HPr(Ser) kinase of Streptococcus salivarius: purification, properties, and cloning of the hprK gene, J Bacteriol, vol.181, pp.709-717, 1999.

E. D. Brown, Conserved P-loop GTPases of unknown function in bacteria: an emerging and vital ensemble in bacterial physiology, Biochemistry and Cell Biology, vol.83, issue.6, pp.738-746, 2005.
DOI : 10.1139/o05-162

W. Bujalowski, M. M. Klonowska, and M. J. Jezewska, Oligomeric structure of Escherichia coli primary replicative helicase DnaB protein, J Biol Chem, vol.269, pp.31350-31358, 1994.

G. Butland, J. M. Peregrin-alvarez, J. Li, W. Yang, X. Yang et al., Interaction network containing conserved and essential protein complexes in Escherichia coli, Nature, vol.8, issue.7025, pp.531-537, 2005.
DOI : 10.1093/nar/25.17.3389

S. K. Choi, J. H. Lee, W. L. Zoll, W. C. Merrick, and T. E. Dever, Promotion of Met-tRNAiMet Binding to Ribosomes by yIF2, a Bacterial IF2 Homolog in Yeast, Science, vol.280, issue.5370, pp.1757-1760, 1998.
DOI : 10.1126/science.280.5370.1757

C. Chothia and J. Janin, Principles of protein???protein recognition, Nature, vol.71, issue.5520, pp.705-708, 1975.
DOI : 10.1038/256705a0

L. Cladiere, K. Hamze, E. Madec, V. M. Levdikov, A. J. Wilkinson et al., The GTPase, CpgA(YloQ), a putative translation factor, is implicated in morphogenesis in Bacillus subtilis, Molecular Genetics and Genomics, vol.66, issue.4, pp.409-420, 2006.
DOI : 10.1007/s00438-006-0097-9

S. N. Cohen, A. C. Chang, and L. Hsu, Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA, Proceedings of the National Academy of Sciences, vol.69, issue.8, pp.2110-2114, 1972.
DOI : 10.1073/pnas.69.8.2110

G. Damaschun, H. Damaschun, K. Gast, R. Misselwitz, D. Zirwer et al., Physical and conformational properties of staphylokinase in solution, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.1161, issue.2-3, pp.244-248, 1993.
DOI : 10.1016/0167-4838(93)90220-L

A. T. Deyrup, S. Krishnan, B. N. Cockburn, and N. B. Schwartz, Deletion and Site-directed Mutagenesis of the ATP-binding Motif (P-loop) in the Bifunctional Murine Atp-Sulfurylase/Adenosine 5'-Phosphosulfate Kinase Enzyme, Journal of Biological Chemistry, vol.273, issue.16, pp.9450-9456, 1998.
DOI : 10.1074/jbc.273.16.9450

I. Donmez and S. S. Patel, Mechanisms of a ring shaped helicase, Nucleic Acids Research, vol.34, issue.15, pp.4216-4224, 2006.
DOI : 10.1093/nar/gkl508

G. Fang, E. Rocha, and A. Danchin, How Essential Are Nonessential Genes?, Molecular Biology and Evolution, vol.22, issue.11, pp.2147-2156, 2005.
DOI : 10.1093/molbev/msi211

S. Fieulaine, S. Morera, S. Poncet, V. Monedero, V. Gueguen-chaignon et al., X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain, The EMBO Journal, vol.20, issue.15, pp.3917-3927, 2001.
DOI : 10.1093/emboj/20.15.3917

L. R. Finger and J. P. Richardson, Stabilization of the hexameric form of Escherichia coli protein rho under ATP hydrolysis conditions, Journal of Molecular Biology, vol.156, issue.1, pp.203-219, 1982.
DOI : 10.1016/0022-2836(82)90467-3

C. Fischer, C. Geourjon, C. Bourson, and J. Deutscher, Cloning and characterization of the Bacillus subtilis prkA gene encoding a novel serine protein kinase, Gene, vol.168, issue.1, pp.55-60, 1996.
DOI : 10.1016/0378-1119(95)00758-X
URL : https://hal.archives-ouvertes.fr/hal-00314058

C. Freiberg, B. Wieland, F. Spaltmann, K. Ehlert, H. Brotz et al., Identification of novel essential Escherichia coli genes conserved among pathogenic bacteria, J Mol Microbiol Biotechnol, vol.3, pp.483-489, 2001.

A. Galinier, J. P. Lavergne, C. Geourjon, S. Fieulaine, S. Nessler et al., A New Family of Phosphotransferases with a P-loop Motif, Journal of Biological Chemistry, vol.277, issue.13, pp.11362-11367, 2002.
DOI : 10.1074/jbc.M109527200
URL : https://hal.archives-ouvertes.fr/hal-00314055

R. Gasper, A. Scrima, and A. Wittinghofer, Structural Insights into HypB, a GTP-binding Protein That Regulates Metal Binding, Journal of Biological Chemistry, vol.281, issue.37, pp.27492-27502, 2006.
DOI : 10.1074/jbc.M600809200

F. Gentile, P. Amodeo, F. Febbraio, F. Picaro, A. Motta et al., SDS-resistant Active and Thermostable Dimers Are Obtained from the Dissociation of Homotetrameric beta -Glycosidase from Hyperthermophilic Sulfolobus solfataricus in SDS. STABILIZING ROLE OF THE A-C INTERMONOMERIC INTERFACE, Journal of Biological Chemistry, vol.277, issue.46, pp.44050-44060, 2002.
DOI : 10.1074/jbc.M206761200

C. Geourjon, C. Orelle, E. Steinfels, C. Blanchet, G. Deleage et al., A common mechanism for ATP hydrolysis in ABC transporter and helicase superfamilies, Trends in Biochemical Sciences, vol.26, issue.9, pp.539-544, 2001.
DOI : 10.1016/S0968-0004(01)01907-7
URL : https://hal.archives-ouvertes.fr/hal-00312995

A. E. Gorbalenya and E. V. Koonin, Helicases: amino acid sequence comparisons and structure-function relationships, Current Opinion in Structural Biology, vol.3, issue.3, pp.419-429, 1993.
DOI : 10.1016/S0959-440X(05)80116-2

C. Grangeasse, P. Doublet, E. Vaganay, C. Vincent, G. Deleage et al., Characterization of a bacterial gene encoding an autophosphorylating protein tyrosine kinase, Gene, vol.204, issue.1-2, pp.259-265, 1997.
DOI : 10.1016/S0378-1119(97)00554-4
URL : https://hal.archives-ouvertes.fr/hal-00313216

C. F. Higgins and K. J. Linton, The ATP switch model for ABC transporters, Nature Structural & Molecular Biology, vol.173, issue.10, pp.918-926, 2004.
DOI : 10.1073/pnas.262659699

A. Hunt, J. P. Rawlins, H. B. Thomaides, and J. Errington, Functional analysis of 11 putative essential genes in Bacillus subtilis, Microbiology, vol.152, issue.10, pp.2895-2907, 2006.
DOI : 10.1099/mic.0.29152-0

L. M. Iyer, D. D. Leipe, E. V. Koonin, and L. Aravind, Evolutionary history and higher order classification of AAA+ ATPases, Journal of Structural Biology, vol.146, issue.1-2, pp.11-31, 2004.
DOI : 10.1016/j.jsb.2003.10.010

R. Jaenicke and H. Lilie, Folding and association of oligomeric and multimeric proteins, Adv Protein Chem, vol.53, pp.329-401, 2000.
DOI : 10.1016/S0065-3233(00)53007-1

J. Janin, S. Miller, and C. Chothia, Surface, subunit interfaces and interior of oligomeric proteins, Journal of Molecular Biology, vol.204, issue.1, pp.155-164, 1988.
DOI : 10.1016/0022-2836(88)90606-7

J. M. Jault, S. Fieulaine, S. Nessler, P. Gonzalo, D. Pietro et al., The HPr Kinase from Bacillus subtilis Is a Homo-oligomeric Enzyme Which Exhibits Strong Positive Cooperativity for Nucleotide and Fructose 1,6-Bisphosphate Binding, Journal of Biological Chemistry, vol.275, issue.3, pp.1773-1780, 2000.
DOI : 10.1074/jbc.275.3.1773
URL : https://hal.archives-ouvertes.fr/hal-00313623

S. Jones and J. M. Thornton, Protein-protein interactions: A review of protein dimer structures, Progress in Biophysics and Molecular Biology, vol.63, issue.1, pp.31-65, 1995.
DOI : 10.1016/0079-6107(94)00008-W

I. K. Jordan, I. B. Rogozin, Y. I. Wolf, and E. V. Koonin, Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in Bacteria, Genome Research, vol.12, issue.6, pp.962-968, 2002.
DOI : 10.1101/gr.87702

K. Kobayashi, S. D. Ehrlich, A. Albertini, G. Amati, K. K. Andersen et al., Essential Bacillus subtilis genes, Proceedings of the National Academy of Sciences, vol.100, issue.8, pp.4678-4683, 2003.
DOI : 10.1073/pnas.0730515100
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153615

E. V. Koonin and L. Aravind, The NACHT family ??? a new group of predicted NTPases implicated in apoptosis and MHC transcription activation, Trends in Biochemical Sciences, vol.25, issue.5, pp.223-224, 2000.
DOI : 10.1016/S0968-0004(00)01577-2

E. V. Koonin, Y. I. Wolf, and L. Aravind, Protein fold recognition using sequence profiles and its application in structural genomics, Adv Protein Chem, vol.54, pp.245-275, 2000.
DOI : 10.1016/S0065-3233(00)54008-X

M. Kravanja, R. Engelmann, V. Dossonnet, M. Bluggel, H. E. Meyer et al., The hprK gene of Enterococcus faecalis encodes a novel bifunctional enzyme: the HPr kinase/phosphatase, Molecular Microbiology, vol.271, issue.1, pp.59-66, 1999.
DOI : 10.1016/S0378-1097(98)00065-2

F. Kunst, N. Ogasawara, I. Moszer, A. M. Albertini, G. Alloni et al., The complete genome sequence of the gram-positive bacterium Bacillus subtilis, Nature, vol.141, issue.6657, pp.249-256, 1997.
DOI : 10.1038/36786

U. K. Laemmli, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, Nature, vol.244, issue.5259, pp.680-685, 1970.
DOI : 10.1038/227680a0

T. A. Larsen, A. J. Olson, and D. S. Goodsell, Morphology of protein???protein interfaces, Structure, vol.6, issue.4, pp.421-427, 1998.
DOI : 10.1016/S0969-2126(98)00044-6

T. M. Laue, B. D. Shah, T. M. Ridgeway, and S. L. Pelletier, Computer-aided interpretation of analytical sedimentation data for proteins. Analytical Ultracentrifugation in Biochemistry and Polymer Science, pp.90-125, 1992.

J. Lebowitz, S. Kar, E. Braswell, S. Mcpherson, and D. L. Richard, Human immunodeficiency virus-1 reverse transcriptase heterodimer stability, Protein Science, vol.61, issue.9, pp.1374-1382, 1994.
DOI : 10.1002/pro.5560030903

D. D. Leipe, L. Aravind, N. V. Grishin, and E. V. Koonin, The bacterial replicative helicase DnaB evolved from a RecA duplication, Genome Res, vol.10, pp.5-16, 2000.

D. D. Leipe, E. V. Koonin, and L. Aravind, Evolution and Classification of P-loop Kinases and Related Proteins, Journal of Molecular Biology, vol.333, issue.4, pp.781-815, 2003.
DOI : 10.1016/j.jmb.2003.08.040

D. D. Leipe, Y. I. Wolf, E. V. Koonin, and L. Aravind, Classification and evolution of P-loop GTPases and related ATPases, Journal of Molecular Biology, vol.317, issue.1, pp.41-72, 2002.
DOI : 10.1006/jmbi.2001.5378

T. A. Leonard, P. J. Butler, and J. Lowe, Bacterial chromosome segregation: structure and DNA binding of the Soj dimer ? a conserved biological switch, The EMBO Journal, vol.19, issue.2, pp.270-282, 2005.
DOI : 10.1038/sj.emboj.7600530

C. G. Lerner, P. J. Hajduk, R. Wagner, F. L. Wagenaar, C. Woodall et al., From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae, From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae, pp.395-404, 2007.
DOI : 10.1111/j.1747-0285.2007.00521.x

T. M. Lohman and K. P. Bjornson, Mechanisms of Helicase-Catalyzed DNA Unwinding, Annual Review of Biochemistry, vol.65, issue.1, pp.169-214, 1996.
DOI : 10.1146/annurev.bi.65.070196.001125

A. N. Lupas and J. Martin, AAA proteins, Current Opinion in Structural Biology, vol.12, issue.6, pp.746-753, 2002.
DOI : 10.1016/S0959-440X(02)00388-3

J. Lutkenhaus and M. Sundaramoorthy, MinD and role of the deviant Walker A motif, dimerization and membrane binding in oscillation, Molecular Microbiology, vol.276, issue.2, pp.295-303, 2003.
DOI : 10.1046/j.1365-2958.2003.03427.x

L. Ma, G. F. King, and L. Rothfield, Positioning of the MinE binding site on the MinD surface suggests a plausible mechanism for activation of the Escherichia coli MinD ATPase during division site selection, Molecular Microbiology, vol.92, issue.1, pp.99-108, 2004.
DOI : 10.1111/j.1365-2958.2004.04265.x

I. G. Macara, K. M. Lounsbury, S. A. Richards, C. Mckiernan, and D. Bar-sagi, The Ras superfamily of GTPases, Faseb J, vol.10, pp.625-630, 1996.

J. A. Marquez, S. Hasenbein, B. Koch, S. Fieulaine, S. Nessler et al., at 1.95 ?? resolution: Mimicking the product/substrate of the phospho transfer reactions, Proceedings of the National Academy of Sciences, vol.99, issue.6, pp.3458-3463, 2002.
DOI : 10.1073/pnas.052461499
URL : https://hal.archives-ouvertes.fr/hal-01440085

S. Miller, The structure of interfaces between subunits of dimeric and tetrameric proteins, "Protein Engineering, Design and Selection", vol.3, issue.2, pp.77-83, 1989.
DOI : 10.1093/protein/3.2.77

E. J. Milner-white, J. R. Coggins, and I. A. Anton, Evidence for an ancestral core structure in nucleotide-binding proteins with the type A motif, Journal of Molecular Biology, vol.221, issue.3, pp.751-754, 1991.
DOI : 10.1016/0022-2836(91)80170-Y

A. G. Murzin, S. E. Brenner, T. Hubbard, and C. Chothia, SCOP: A structural classification of proteins database for the investigation of sequences and structures, Journal of Molecular Biology, vol.247, issue.4, pp.536-540, 1995.
DOI : 10.1016/S0022-2836(05)80134-2

T. Ogura and A. J. Wilkinson, AAA+ superfamily ATPases: common structure-diverse function, Genes to Cells, vol.4, issue.7, pp.575-597, 2001.
DOI : 10.1101/gad.864401

J. Park, M. Lappe, and S. A. Teichmann, Mapping protein family interactions: intramolecular and intermolecular protein family interaction repertoires in the PDB and yeast11Edited by J. Karn, Journal of Molecular Biology, vol.307, issue.3, pp.929-938, 2001.
DOI : 10.1006/jmbi.2001.4526

S. Patel and M. Latterich, The AAA team: related ATPases with diverse functions, Trends in Cell Biology, vol.8, issue.2, pp.65-71, 1998.
DOI : 10.1016/S0962-8924(97)01212-9

K. Peters and F. M. Richards, Chemical Cross-Linking: Reagents and Problems in Studies of Membrane Structure, Annual Review of Biochemistry, vol.46, issue.1, pp.523-551, 1977.
DOI : 10.1146/annurev.bi.46.070177.002515

E. Prossnitz, K. Nikaido, S. J. Ulbrich, and G. F. Ames, Formaldehyde and photoactivatable cross-linking of the periplasmic binding protein to a membrane component of the histidine transport system of Salmonella typhimurium, J Biol Chem, vol.263, pp.17917-17920, 1988.

M. E. Pullman, H. S. Penefsky, A. Datta, and E. Racker, Partial resolution of the enzymes catalyzing oxidative phosphorylation. I. Purification and properties of soluble dinitrophenol-stimulated adenosine triphosphatase, J Biol Chem, vol.235, pp.3322-3329, 1960.

H. Ramstrom, S. Sanglier, E. Leize-wagner, C. Philippe, A. Van-dorsselaer et al., Properties and Regulation of the Bifunctional Enzyme HPr Kinase/Phosphatase in Bacillus subtilis, Journal of Biological Chemistry, vol.278, issue.2, pp.1174-1185, 2003.
DOI : 10.1074/jbc.M209052200

L. Ren, E. Chang, K. Makky, A. L. Haas, B. Kaboord et al., Glutathione S-transferase pull-down assays using dehydrated immobilized glutathione resin, Analytical Biochemistry, vol.322, issue.2, pp.164-169, 2003.
DOI : 10.1016/j.ab.2003.07.023

M. Saraste, P. R. Sibbald, and A. Wittinghofer, The P-loop ??? a common motif in ATP- and GTP-binding proteins, Trends in Biochemical Sciences, vol.15, issue.11, pp.430-434, 1990.
DOI : 10.1016/0968-0004(90)90281-F

A. Sato, G. Kobayashi, H. Hayashi, H. Yoshida, A. Wada et al., The GTP binding protein Obg homolog ObgE is involved in ribosome maturation, Genes to Cells, vol.322, issue.5, pp.393-408, 2005.
DOI : 10.1111/j.1365-2443.2005.00851.x

K. Sato, H. Mori, M. Yoshida, and S. Mizushima, Characterization of a Potential Catalytic Residue, Asp-133, in the High Affinity ATP-binding Site of Escherichia coli SecA, Translocation ATPase, Journal of Biological Chemistry, vol.271, issue.29, pp.17439-17444, 1996.
DOI : 10.1074/jbc.271.29.17439

E. Schneider and S. Hunke, ATP-binding-cassette (ABC) transport systems: Functional and structural aspects of the ATP-hydrolyzing subunits/domains, FEMS Microbiology Reviews, vol.22, issue.1, pp.1-20, 1998.
DOI : 10.1111/j.1574-6976.1998.tb00358.x

P. Schuck, Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling, Biophysical Journal, vol.78, issue.3, pp.1606-1619, 2000.
DOI : 10.1016/S0006-3495(00)76713-0

G. E. Schulz, Binding of nucleotides by proteins, Current Opinion in Structural Biology, vol.2, issue.1, pp.61-67, 1992.
DOI : 10.1016/0959-440X(92)90178-A

T. Schweins, M. Geyer, K. Scheffzek, A. Warshel, H. R. Kalbitzer et al., Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins, Nature Structural Biology, vol.206, issue.1, pp.36-44, 1995.
DOI : 10.1016/0167-4838(91)90007-M

J. T. Skare, B. M. Ahmer, C. L. Seachord, R. P. Darveau, and K. Postle, Energy transduction between membranes. TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to the outer membrane receptor FepA, J Biol Chem, vol.268, pp.16302-16308, 1993.

D. Soulat, J. M. Jault, B. Duclos, C. Geourjon, A. J. Cozzone et al., Staphylococcus aureus Operates Protein-tyrosine Phosphorylation through a Specific Mechanism, Journal of Biological Chemistry, vol.281, issue.20, pp.14048-14056, 2006.
DOI : 10.1074/jbc.M513600200
URL : https://hal.archives-ouvertes.fr/hal-00313188

M. A. Speed, D. I. Wang, and J. King, Multimeric intermediates in the pathway to the aggregated inclusion body state for P22 tailspike polypeptide chains, Protein Science, vol.18, issue.5, pp.900-908, 1995.
DOI : 10.1002/pro.5560040509

R. M. Story and T. A. Steitz, Structure of the recA protein???ADP complex, Nature, vol.355, issue.6358, pp.374-376, 1992.
DOI : 10.1038/355374a0

R. M. Story, I. T. Weber, and T. A. Steitz, The structure of the E. coli recA protein monomer and polymer, Nature, vol.355, issue.6358, pp.318-325, 1992.
DOI : 10.1038/355318a0

M. J. Teixeira-de-mattos and O. M. Neijssel, Bioenergetic consequences of microbial adaptation to low-nutrient environments, Journal of Biotechnology, vol.59, issue.1-2, pp.117-126, 1997.
DOI : 10.1016/S0168-1656(97)00174-0

A. Teplyakov, G. Obmolova, M. Tordova, N. Thanki, N. Bonander et al., Crystal structure of the YjeE protein fromHaemophilus influenzae: A putative Atpase involved in cell wall synthesis, Proteins: Structure, Function, and Genetics, vol.22, issue.2, pp.220-226, 2002.
DOI : 10.1002/prot.10114

M. D. Tsai and H. G. Yan, Mechanism of adenylate kinase: site-directed mutagenesis versus x-ray and NMR, Biochemistry, vol.30, issue.28, pp.6806-6818, 1991.
DOI : 10.1021/bi00242a002

H. C. Tsui, G. Zhao, G. Feng, H. C. Leung, and M. E. Winkler, The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase, Molecular Microbiology, vol.175, issue.1, pp.189-202, 1994.
DOI : 10.1016/0378-1119(85)90120-9

I. R. Vetter and A. Wittinghofer, Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer, Quarterly Reviews of Biophysics, vol.32, issue.1, pp.1-56, 1999.
DOI : 10.1017/S0033583599003480

I. R. Vetter and A. Wittinghofer, The Guanine Nucleotide-Binding Switch in Three Dimensions, Science, vol.294, issue.5545, pp.1299-1304, 2001.
DOI : 10.1126/science.1062023

G. Waksman, E. Lanka, and J. M. Carazo, Helicases as nucleic acid unwinding machines, Nature Structural Biology, vol.7, issue.1, pp.20-22, 2000.
DOI : 10.1038/71215

J. E. Walker, M. Saraste, M. J. Runswick, and N. J. Gay, Distantly related sequences in the alpha-and beta-subunits of ATP synthase, myosin, kinases and other ATPrequiring enzymes and a common nucleotide binding fold, Embo J, vol.1, pp.945-951, 1982.

C. Walsh, Antibiotics: Actions, Origins, Resistance, 2003.
DOI : 10.1128/9781555817886

D. Xu, S. L. Lin, and R. Nussinov, Protein binding versus protein folding: the role of hydrophilic bridges in protein associations, Journal of Molecular Biology, vol.265, issue.1, pp.68-84, 1997.
DOI : 10.1006/jmbi.1996.0712

H. G. Yan, Z. T. Shi, and M. D. Tsai, Mechanism of adenylate kinase. Structural and functional demonstration of arginine-138 as a key catalytic residue that cannot be replaced by lysine, Biochemistry, vol.29, issue.27, pp.6385-6392, 1990.
DOI : 10.1021/bi00479a007

M. Yoshida and T. Amano, A common topology of proteins catalyzing ATP-triggered reactions, FEBS Letters, vol.123, issue.1, pp.1-5, 1995.
DOI : 10.1016/0014-5793(94)01438-7

T. Zhou and B. P. Rosen, Asp45 Is a Mg2+ Ligand in the ArsA ATPase, Journal of Biological Chemistry, vol.274, issue.20, pp.13854-13858, 1999.
DOI : 10.1074/jbc.274.20.13854

». Atpase, C. Johanna, A. Karst, T. L. Foucher, D. Campbell et al., Soumis Oligomerisation of an 'essential' bacterial enzyme of Bacillus subtilis

J. C. Karst, Anne-Emmanuelle Foucher 1 , Tracey L

A. Allali-hassani, T. L. Campbell, A. Ho, J. W. Schertzer, and E. D. Brown, protein of unknown function, Biochemical Journal, vol.384, issue.3, pp.577-584, 2004.
DOI : 10.1042/BJ20041082

D. Barilla, M. F. Rosenberg, U. Nobbmann, H. , and F. , Bacterial DNA segregation dynamics mediated by the polymerizing protein ParF, The EMBO Journal, vol.335, issue.7, pp.1453-1464, 2005.
DOI : 10.1038/sj.emboj.7600619

E. D. Brown, W. , and G. D. , New Targets and Screening Approaches in Antimicrobial Drug Discovery, Chemical Reviews, vol.105, issue.2, pp.759-774, 2005.
DOI : 10.1021/cr030116o

T. L. Campbell, C. S. Ederer, A. Allali-hassani, and E. D. Brown, Isolation of the rstA Gene as a Multicopy Suppressor of YjeE, an Essential ATPase of Unknown Function in Escherichia coli, Journal of Bacteriology, vol.189, issue.8, pp.3318-3321, 2007.
DOI : 10.1128/JB.00131-06

L. J. Crowther, A. Yamagata, L. Craig, J. A. Tainer, and M. S. Donnenberg, The ATPase Activity of BfpD Is Greatly Enhanced by Zinc and Allosteric Interactions with Other Bfp Proteins, Journal of Biological Chemistry, vol.280, issue.26, pp.24839-24848, 2005.
DOI : 10.1074/jbc.M500253200

J. Dam and P. Schuck, Calculating Sedimentation Coefficient Distributions by Direct Modeling of Sedimentation Velocity Concentration Profiles, Methods Enzymol, vol.384, pp.185-212, 2004.
DOI : 10.1016/S0076-6879(04)84012-6

G. Fang, E. Rocha, and A. Danchin, How Essential Are Nonessential Genes?, Molecular Biology and Evolution, vol.22, issue.11, pp.2147-2156, 2005.
DOI : 10.1093/molbev/msi211

M. Y. Galperin and E. V. Koonin, 'Conserved hypothetical' proteins: prioritization of targets for experimental study, Nucleic Acids Research, vol.32, issue.18, pp.5452-5463, 2004.
DOI : 10.1093/nar/gkh885

Z. Hu, C. Saez, and J. Lutkenhaus, Recruitment of MinC, an Inhibitor of Z-Ring Formation, to the Membrane in Escherichia coli: Role of MinD and MinE, Journal of Bacteriology, vol.185, issue.1, pp.196-203, 2003.
DOI : 10.1128/JB.185.1.196-203.2003

A. Hunt, J. P. Rawlins, H. B. Thomaides, and J. And-errington, Functional analysis of 11 putative essential genes in Bacillus subtilis, Microbiology, vol.152, issue.10, pp.2895-2907, 2006.
DOI : 10.1099/mic.0.29152-0

J. M. Jault, D. Pietro, A. Falson, P. Gautheron, and D. C. , Alteration of apparent negative cooperativity of ATPase activity by alpha-subunit glutamine 173 mutation in yeast mitochondrial F1. Correlation with impaired nucleotide interaction at a regulatory site, J Biol Chem, vol.266, pp.8073-8078, 1991.
URL : https://hal.archives-ouvertes.fr/hal-00313643

E. V. Koonin, Y. I. Wolf, A. , and L. , Protein fold recognition using sequence profiles and its application in structural genomics, Adv Protein Chem, vol.54, pp.245-275, 2000.
DOI : 10.1016/S0065-3233(00)54008-X

U. K. Laemmli, Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, Nature, vol.244, issue.5259, pp.680-685, 1970.
DOI : 10.1038/227680a0

H. Langen, B. Takacs, S. Evers, P. Berndt, H. W. Lahm et al., Two-dimensional map of the proteome of Haemophilus influenzae, Electrophoresis, vol.21, issue.2, pp.411-429, 2000.
DOI : 10.1002/(SICI)1522-2683(20000101)21:2<411::AID-ELPS411>3.3.CO;2-W

A. N. Lupas, M. , and J. , AAA proteins, Current Opinion in Structural Biology, vol.12, issue.6, pp.746-753, 2002.
DOI : 10.1016/S0959-440X(02)00388-3

R. J. Roberts, Identifying Protein Function???A Call for Community Action, PLoS Biology, vol.153, issue.3, p.42, 2004.
DOI : 10.1371/journal.pbio.0020042

E. Foucher, C. S. Mangat, J. Jault, &. Eric, and D. Brown, 56 th Annual Conference Canadian Society of Microbiologists, 2006.

J. Jault, Journée de l'IBS, 2007.

J. Jault, Journée de l'EDCSV, 2007.