L. Colonne, Citrate 200 !M (Tampon G), est développée avec un tampon 20 mM Tris pH 7, NaCl, vol.4, issue.44

B. Gapped and P. , A New Generation of Protein Database Search Programs, Nucleic Acids Res, vol.25, pp.3389-3402

N. C. Andrews, The iron transporter DMT1, The International Journal of Biochemistry & Cell Biology, vol.31, issue.10, 1999.
DOI : 10.1016/S1357-2725(99)00065-5

N. Aziz and H. N. Munro, Iron Regulates Ferritin mRNA Translation Through a Segment of its 5, 1987.

C. F. Babbs and M. G. Steiner, [11] Detection and quantitation of hydroxyl radical using dimethyl sulfoxide as molecular probe, 1990.
DOI : 10.1016/0076-6879(90)86103-3

J. P. Basilion, M. C. Kennedy, H. Beinert, C. M. Massinople, R. D. Klausner et al., Overexpression of Iron-Responsive Element-Binding Protein and Its Analytical Characterization as the RNA-Binding Form, Devoid of an Iron-Sulfur Cluster, Archives of Biochemistry and Biophysics, vol.311, issue.2, 1994.
DOI : 10.1006/abbi.1994.1270

J. L. Beard, H. Dawson, and D. J. Piñero, Iron Metabolism: A Comprehensive Review, Nutrition Reviews, vol.54, issue.10, 1996.
DOI : 10.1111/j.1753-4887.1996.tb03794.x

B. S. Berlett and E. R. Stadtman, Protein Oxidation in Aging, Disease and Oxidative Stress, 1997.

A. J. Bettany, R. S. Eisenstein, and H. N. Munro, Mutagenesis of the Iron-Regulatory Element Further Defines a Role for RNA Secondary Structure in the Regulation of Ferritin and Transferrin Receptor Expression, 1992.

C. Bouton, M. Raveau, and J. Drapier, Modulation of Iron Regulatory Protein Functions. Further insights into the Role of Nitrogen-and Oxygen-Derived Reactive Species, 1996.

C. Bouton, Nitrosative and oxidative modulation of iron regulatory proteins, Cellular and Molecular Life Sciences, vol.55, issue.9, 1999.
DOI : 10.1007/s000180050355

V. Braun and H. Killmann, Bacterial solutions to the iron-supply problem, Trends in Biochemical Sciences, vol.24, issue.3, 1999.
DOI : 10.1016/S0968-0004(99)01359-6

O. Byron and R. J. Gilbert, Neutron Scattering : Good News for, Biotechnology, 2000.
DOI : 10.1016/s0958-1669(99)00057-9

F. Canonne-hergaux, S. Gruenheid, P. Ponka, and P. Gros, Cellular and Subcellular Localization of the Nramp2 Iron Transporter in the intestinal Brush Border and regulation by Dietary Iron, 1999.

J. L. Casey, D. M. Koeller, V. C. Ramin, R. D. Klausner, and J. B. Harford, Iron Regulation of Transferrin Receptor mRNA Levels Requires Iron-Responsive Elements and a Rapid Turnover Derterminant in the 3, 1989.

/. Gallium and . Uptake, Increased Activity of Iron Regulatory Protein-1, and Decreased Ferritin Production

A. Constable, S. Quick, N. K. Gray, and M. W. Hentze, Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function?, Proceedings of the National Academy of Sciences, vol.89, issue.10, 1992.
DOI : 10.1073/pnas.89.10.4554

T. Dandekar, R. Stripecke, N. K. Gray, B. Goosen, A. Constable et al., Identification of a Novel Iron-Responsive Element in Murine ans Human Erythroid, Aminolevulinic Acid Synthase mRNA, 1991.

V. Davasse and J. Moulis, Design and Functional Expression in Escherichia Coli of a Synthetic Gene Encoding Clostridium Pasteurianum, 1992.

J. Drapier, H. Hirling, J. Wietzerbin, P. Kaldy, and L. C. Kühn, Biosynthesis of Nitric Oxide Activates Iron Regulatory Factor in Macrophages, 1993.

R. S. Eisenstein, Discovery of the Ceruloplasmin Homologue Hephaestin: New Insight into the Copper/Iron Connection, Nutrition Reviews, vol.58, issue.1, 2000.
DOI : 10.1111/j.1753-4887.2000.tb01821.x

A. Emery-goodman, H. Hirling, L. Scarpellino, B. Henderson, and L. C. Kühn, Iron regulatory factor expressed from recombinant baculovirus: conversion between the RNA-binding apoprotein and Fe-S cluster containing aconitase, Nucleic Acids Research, vol.21, issue.6, pp.1457-1461, 1993.
DOI : 10.1093/nar/21.6.1457

S. Fields and O. Song, A novel genetic system to detect protein???protein interactions, Nature, vol.340, issue.6230, 1989.
DOI : 10.1038/340245a0

T. Finkel, Oxygen radicals and signaling, Current Opinion in Cell Biology, vol.10, issue.2, 1998.
DOI : 10.1016/S0955-0674(98)80147-6

D. Frishman and M. W. Hentze, Conservation of Aconitase Residues Revealed by Multiple Sequence Analysis. Implications for Structure/Function Relationships, European Journal of Biochemistry, vol.112, issue.1, 1996.
DOI : 10.1093/nar/24.1.21

J. D. Gower, G. Healing, and C. J. Green, Determination of desferrioxamine-available iron in biological tissues by high-pressure liquid chromatography, Analytical Biochemistry, vol.180, issue.1, 1989.
DOI : 10.1016/0003-2697(89)90099-7

H. Gunshin, B. Mackenzie, U. V. Berger, Y. Gunshin, M. F. Romero et al., Cloning and Characterization of a Mammalian Proton-Coupled Metal-Ion Transporter, 1997.

J. A. Gutierrez, J. Yu, S. Rivera, and M. Wessling-resnick, Functionnal Expression, Cloning and Characterization of SFT, a Stimulator of Fe Transport, 1997.

K. Hantke, Iron and metal regulation in bacteria, Current Opinion in Microbiology, vol.4, issue.2, 2001.
DOI : 10.1016/S1369-5274(00)00184-3

K. Harada and A. D. Frankel, Identification of two novel arginine binding DNAs, 1995.

D. N. Heiger, High Performance Capillary Electrophoreses -An Introduction, 1992.

B. R. Henderson, E. Menotti, and L. C. Kühn, Iron Regulatory Proteins 1 and 2 Bind Distinct Sets of RNA Target Sequences, 1996.

M. W. Hentze, T. A. Rouault, J. B. Harford, and R. D. Klausner, Oxidation-Reduction and the Molecular Mecanism of a regulatory RNA-Protein Interaction, 1989.

H. Hirling, A. Emery-goodman, N. Thompson, B. Neupert, C. Seiser et al., Expression of Active Iron Regulatory Factor from a Full-Length Human cDNA by in vitro Transcription, 1992.

R. H. Holm, P. Kennepohl, and E. I. Solomon, Structural and Functional Aspects of Metal Sites in Biology, Chemical Reviews, vol.96, issue.7, pp.2239-2314, 1996.
DOI : 10.1021/cr9500390

J. Hu and J. R. Connor, Demonstration and Characterization of the Iron Regulatory, 1996.

H. Ito, Y. Fukuda, K. Murata, and A. Kimura, Transformation of Intact Yeast Celles Treated with Alkali Cations, 1983.

P. Kaldy, E. Menotti, R. Moret, and L. Kühn, Identification of RNA-Binding, 1999.

K. D. Karlin, Metalloenzymes, Structural Motifs and Inorganic Models Science, pp.701-708, 1993.

Y. Ke, J. Wu, E. A. Leibold, W. E. Walden, and . E. Theil, Loops and Bulge/Loops in Iron-responsive Element Isoforms Influence Iron Regulatory Protein Binding: FINE-TUNING OF mRNA REGULATION?, Journal of Biological Chemistry, vol.273, issue.37, 1998.
DOI : 10.1074/jbc.273.37.23637

S. M. Kelly and N. C. Price, The application of circular dichroism to studies of protein folding and unfolding, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.1338, issue.2, 1997.
DOI : 10.1016/S0167-4838(96)00190-2

P. J. Kiley and H. Beinert, Oxygen sensing by the global regulator, FNR: the role of the iron-sulfur cluster, FEMS Microbiology Reviews, vol.22, issue.5, 1999.
DOI : 10.1111/j.1574-6976.1998.tb00375.x

. Mechanism-of-ferritin-iron and . Uptake, Activity of the H-Chain and Deletion Mapping of the Ferro-Oxidase Site. A Study of Iron Uptake and Ferro-Oxidase Activity of Human Liver, Recombinant H-Chain Ferritins, and of Two H-Chain Deletion Mutants

G. R. Martinez, J. Ravanat, M. H. Medeiros, J. Cadet, D. Mascio et al., Synthesis of a Naphtalene Endoperoxyde as a Source of 18 O-labeled Singlet Oxygen for Mecanistic Studies, 2000.

J. Meyer, J. Gagnon, L. C. Sieker, A. Van-dorsselaer, and J. Moulis, Rubredoxin from Clostridium Thermosaccharolyticum, Mass-Spectrometric and Preliminary Crystallographic Data, 1990.

G. Minotti, G. Cairo, and E. Monti, Role of Iron in Anthracycline Cardiotoxicity : New Tunes of an Old Song ?, 1999.

J. Moulis and M. J. , Characterization of the selenium-substituted 2[4Fe-4Se] ferredoxin from Clostridium pasteurianum, Biochemistry, vol.21, issue.19, pp.4762-4771, 1982.
DOI : 10.1021/bi00262a037

J. Moulis, N. Scherrer, J. Gagnon, E. Forest, Y. Pétillot et al., Primary Structure of Chromatium Tepidum High-Potential Iron-Sulfur, 1993.

Y. Nakai, M. Nakai, H. Hayashi, and H. Kagamiyama, Nuclear Localization of Yeast Nfs1p Is Required for Cell Survival, Journal of Biological Chemistry, vol.276, issue.11, 2001.
DOI : 10.1074/jbc.M007878200

K. Pantopoulos, N. K. Gray, and M. W. Hentze, Differential Regulation of Two Related RNA-Binding Proteins, Iron Regulatory Protein, 1995.

K. Pantopoulos and M. W. Hentze, Activation of Iron Regulatory Protein-1 by Oxydative Stress in Vitro, 1998.

Y. Pétillot, E. Forest, J. Meyer, and J. Moulis, Observation of Holoprotein Molecular Ions of Several Ferredoxins by Electrospray-Ionization-Mass Spectrometry, Analytical Biochemistry, vol.228, issue.1, 1995.
DOI : 10.1006/abio.1995.1314

C. C. Philpott, D. Haile, T. A. Rouault, and R. D. Klausner, Modification of a Free Fe-S Cluster Cysteine Residue in the Active Iron-Responsive Element-Binding Protein Prevents RNA Binding, 1993.

P. Ponka, C. Beaumont, and D. R. Richardson, Function and Regulation of Transferrin and Ferritin, 1998.

A. H. Robbins and C. D. Stout, The structure of aconitase, Proteins: Structure, Function, and Genetics, vol.745, issue.4, 1989.
DOI : 10.1002/prot.340050406

A. Bacteriophage and T. Polymerase, Promoter System for Controled Exclusive Expression of Specific Genes

P. Uetz, L. Giot, G. Cagney, T. A. Mansfield, R. S. Judson et al., A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae, 2000.

. Hephaestin and . Ceruloplasmin, Homologue Implicated in Intestinal Iron Transport, is Defective in the sla Mouse, Nature Genetics, vol.21, issue.195199

G. Weiss, B. Goossen, W. Doppler, D. Fuchs, K. Pantopoulos et al., Translational regulation via Iron-Responsive Elements by the Nitric Oxide, 1993.

T. Yoshida and C. T. Migita, Mechanism of heme degradation by heme oxygenase, Journal of Inorganic Biochemistry, vol.82, issue.1-4, 2000.
DOI : 10.1016/S0162-0134(00)00156-2

S. M. Zeman, D. R. Philips, and D. M. Crothers, Characterization of Covalent Adiamycin-DNA adducts, 1999.