F. Arcamone, B. Camerino, E. Cotta, G. Franceschi, A. Grein et al., New carotenoids fromStreptomyces mediolani n. sp., Experientia, vol.25, issue.3, pp.241-242, 1969.
DOI : 10.1007/BF02034366

G. A. Armstrong and G. A. Armstrong, Carotenoid genetics and biochemistry Comprehensive natural products chemistry Eubacteria show their true colors : genetics of carotenoid pigment biosynthesis from microbes to plants, J. Bacteriol, vol.176, pp.321-352, 1994.

G. A. Armstrong, GENETICS OF EUBACTERIAL CAROTENOID BIOSYNTHESIS: A Colorful Tale, Annual Review of Microbiology, vol.51, issue.1, pp.629-659, 1997.
DOI : 10.1146/annurev.micro.51.1.629

G. A. Armstrong and J. E. Hearst, Genetics and molecular biology of carotenoid pigment biosynthesis, FASEB J, vol.10, pp.228-237, 1996.

N. Arrach, R. Fernandez-martin, E. Cerda-olmedo, and J. Avalos, A single gene for lycopene cyclase, phytoene synthase, and regulation of carotene biosynthesis in Phycomyces, Proceedings of the National Academy of Sciences, vol.98, issue.4, pp.1687-1692, 2001.
DOI : 10.1073/pnas.98.4.1687

N. Arrach, T. J. Schmidhauser, and J. Avalos, Mutants of the carotene cyclase domain of al-2 from Neurospora crassa, Mol. Genet. Genomics, vol.266, pp.914-921, 2002.

A. Bast, G. R. Haenen, R. Van-den-berg, and H. Van-den-berg, Antioxidant effects of carotenoids, Internat. J. Vit. Nutr. Res, vol.68, pp.399-403, 1998.

J. C. Bauernfeind, Carotenoids as colorants and vitamin A precursors, 1981.

M. L. Bianchi, A. Grein, P. Julita, M. P. Marnati, and C. Spalla, Streptomyces mediolani (Arcamone et al.) emend. Bianchi et al. and its production of carotenoids, Z. Allg. Mikrobiol, vol.10, pp.237-244, 1970.

F. Bouvier, A. Harlingue, and B. Camara, Molecular Analysis of Carotenoid Cyclase Inhibition, Archives of Biochemistry and Biophysics, vol.346, issue.1, pp.53-64, 1997.
DOI : 10.1006/abbi.1997.0278

F. Bouvier, A. D-'harlingue, P. Hugueney, E. Marin, A. Marion-poll et al., Xanthophyll biosynthesis: cloning, expression, functional reconstitution, and regulation of ?-cyclohexenyl carotenoid epoxidase from pepper (Capsicum annuum), J. Biol. Chem, vol.271, pp.28861-28867, 1996.

F. Bouvier, Y. Keller, A. Harlingue, and B. Camara, Xanthophyll biosynthesis: molecular and functional characterization of carotenoid hydroxylases from pepper fruits (Capsicum annuum L.), Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1391, issue.3, pp.320-328, 1998.
DOI : 10.1016/S0005-2760(98)00029-0

D. E. Breithaupt and A. Bamedi, Carotenoid Esters in Vegetables and Fruits:?? A Screening with Emphasis on ??-Cryptoxanthin Esters, Journal of Agricultural and Food Chemistry, vol.49, issue.4, pp.2064-2070, 2001.
DOI : 10.1021/jf001276t

D. E. Breithaupt and W. Schwack, Determination of free and bound carotenoids in paprika ( Capsicum annuum L.) by LC/MS, European Food Research and Technology, vol.211, issue.1, pp.52-55, 2000.
DOI : 10.1007/s002170050588

D. E. Breithaupt, W. Schwack, G. Wolf, and W. P. Hammes, Characterization of the triterpenoid 4,4???-diaponeurosporene and its isomers in food-associated bacteria, European Food Research and Technology, vol.213, issue.3, pp.231-233, 2001.
DOI : 10.1007/s002170100358

D. E. Breithaupt, U. Wirt, and A. Bamedi, Differentiation between lutein monoester regioisomers and detection of lutein diesters from marigold flowers (Tagetes erecta L.) and several fruits by liquid chromatography-mass spectrometry, 2002.

D. E. Cane, Isoprenoid biosynthesis: overview. In: Comprehensive natural products chemistry, pp.1-13, 1999.
DOI : 10.1016/b978-0-08-091283-7.00034-5

S. Chen and D. Zhou, Functional domains of aromatase cytochrome P450 inferred from comparative analyses of amino acid sequences and substantiated by site-directed muatgenesis experiments, J. Biol. Chem, vol.267, pp.22587-22594, 1992.

F. Corpet, F. Servant, J. Gouzy, and D. Kahn, ProDom and ProDom-CG: tools for protein domain analysis and whole genome comparisons, Nucleic Acids Research, vol.28, issue.1, pp.267-269, 2000.
DOI : 10.1093/nar/28.1.267
URL : https://hal.archives-ouvertes.fr/hal-00427044

F. X. Cunningham-jr and E. Gantt, One ring or two? Determination of ring number in carotenoids by lycopene ??-cyclases, Proceedings of the National Academy of Sciences, vol.98, issue.5, pp.2905-2910, 2000.
DOI : 10.1073/pnas.051618398

F. X. Cunningham-jr, B. Pogson, Z. Sun, K. A. Mcdonald, D. Dellapenna et al., Functional Analysis of the [beta] and [epsilon] Lycopene Cyclase Enzymes of Arabidopsis Reveals a Mechanism for Control of Cyclic Carotenoid Formation, THE PLANT CELL ONLINE, vol.8, issue.9, pp.1613-1626, 1996.
DOI : 10.1105/tpc.8.9.1613

F. X. Cunningham-jr, Z. Sun, D. Chamovitz, J. Hirschberg, and E. Gantt, Molecular Structure and Enzymatic Function of Lycopene Cyclase from the Cyanobacterium Synechococcus sp Strain PCC7942, THE PLANT CELL ONLINE, vol.6, issue.8, pp.1107-1121, 1994.
DOI : 10.1105/tpc.6.8.1107

F. X. Cunningham-jr and E. Gantt, GENES AND ENZYMES OF CAROTENOID BIOSYNTHESIS IN PLANTS, Annual Review of Plant Physiology and Plant Molecular Biology, vol.49, issue.1, pp.557-583, 1998.
DOI : 10.1146/annurev.arplant.49.1.557

D. Mot, R. Parret, and A. H. , A novel class of self-sufficient cytochrome P450 monooxygenases in prokaryotes, Trends Microbiol, vol.10, 2002.

A. Disch and M. Rohmer, On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts, FEMS Microbiology Letters, vol.168, issue.2, pp.201-208, 1998.
DOI : 10.1111/j.1574-6968.1998.tb13274.x

W. Eisenreich, F. Rohdich, and A. Bacher, Deoxyxylulose phosphate pathway to terpenoids, Trends in Plant Science, vol.6, issue.2, pp.78-84, 2001.
DOI : 10.1016/S1360-1385(00)01812-4

E. Fautz and H. Reichenbach, A simple test for flexirubin-type pigments, FEMS Microbiology Letters, vol.8, issue.2, pp.87-91, 1980.
DOI : 10.1111/j.1574-6968.1980.tb05056.x

P. D. Fraser and P. M. Bramley, The biosynthesis and nutritional uses of carotenoids, Progress in Lipid Research, vol.43, issue.3, pp.228-265, 2004.
DOI : 10.1016/j.plipres.2003.10.002

P. D. Fraser, N. Misawa, H. Linden, S. Yamano, K. Kobayashi et al., Expression in Escherichia coli, purification, and reactivation of the recombinant Erwinia uredovora phytoene desaturase, J. Biol. Chem, vol.267, 1992.

P. D. Fraser, Y. Miura, and N. Misawa, In Vitro Characterization of Astaxanthin Biosynthetic Enzymes, Journal of Biological Chemistry, vol.272, issue.10, pp.6128-6135, 1997.
DOI : 10.1074/jbc.272.10.6128

A. J. Fulco, P450BM-3 and other Inducible Bacterial P450 Cytochromes: Biochemistry and Regulation, Annual Review of Pharmacology and Toxicology, vol.31, issue.1, pp.177-203, 1991.
DOI : 10.1146/annurev.pa.31.040191.001141

D. Garfinkel, Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions, Archives of Biochemistry and Biophysics, vol.77, issue.2, pp.493-509, 1958.
DOI : 10.1016/0003-9861(58)90095-X

T. W. Goodwin, The biochemistry of the carotenoids, 1980.

S. E. Graham and J. A. Peterson, How Similar Are P450s and What Can Their Differences Teach Us?, Archives of Biochemistry and Biophysics, vol.369, issue.1, pp.24-29, 1999.
DOI : 10.1006/abbi.1999.1350

S. Graham-lorence and J. A. Peterson, P450s: structural similarities and functional differences, FASEB J, vol.10, pp.206-214, 1996.

N. Grecz and G. M. Dack, Taxanomically significant color reactions of Brevibacterium linens, J. Bacteriol, vol.82, pp.241-246, 1961.

F. P. Guengerich and T. L. Mcdonald, Mechanisms of cytochrome P-450 catalysis, FASEB J, vol.4, pp.2453-2459, 1990.

F. Guyomarc-'h, A. Binet, and L. Dufosse, Production of carotenoids by Brevibacterium linens: variation among strains, kinetic aspects and HPLC profiles, 2000.

T. Hatae, S. Hara, C. Yokoyama, T. Yabuki, H. Inoue et al., of the EXXR motif, FEBS Letters, vol.266, issue.3, pp.268-272, 1996.
DOI : 10.1016/0014-5793(96)00600-X

A. Hausmann and G. Sandmann, A Single Five-Step Desaturase Is Involved in the Carotenoid Biosynthesis Pathway to ??-Carotene and Torulene in Neurospora crassa, Fungal Genetics and Biology, vol.30, issue.2, pp.147-153, 2000.
DOI : 10.1006/fgbi.2000.1212

A. M. Hays, A. R. Dunn, R. Chiu, H. B. Gray, C. D. Stout et al., Conformational States of Cytochrome P450cam Revealed by Trapping of Synthetic Molecular Wires, Journal of Molecular Biology, vol.344, issue.2, pp.455-469, 2004.
DOI : 10.1016/j.jmb.2004.09.046

S. Hecht, W. Eisenreich, P. Adam, S. Amslinger, K. Kis et al., Studies on the nonmevalonate pathway to terpenes: The role of the GcpE (IspG) protein, Proceedings of the National Academy of Sciences, vol.98, issue.26, pp.14837-14842, 2001.
DOI : 10.1073/pnas.201399298

H. Hemmi, S. Ikejiri, T. Nakayama, and T. Nishino, Fusion-type lycopene ??-cyclase from a thermoacidophilic archaeon Sulfolobus solfataricus, Biochemical and Biophysical Research Communications, vol.305, issue.3, pp.586-591, 2003.
DOI : 10.1016/S0006-291X(03)00798-8

M. Houssaini-iraqui, S. Clavel-seres, N. Rastogi, and H. L. David, Partial physical and functional map of aMycobacterium aurum carotenogenesis operon, Current Microbiology, vol.63, issue.Suppl 1, pp.65-74, 1993.
DOI : 10.1007/BF01577338

M. Houssaini-iraqui, H. L. David, S. Clavel-seres, F. Hilali, and N. Rastogi, Characterization ofcar ??,car Lep, andCrt I genes controlling the biosynthesis of carotenes inMycobacterium aurum, Current Microbiology, vol.63, issue.6, pp.317-322, 1993.
DOI : 10.1007/BF01568954

B. Hundle, M. Alberti, V. Nievelstein, P. Beyer, H. Kleinig et al., Functional assignment of Erwinia herbicola Eho10 carotenoid genes expressed in Escherichia coli, MGG Molecular & General Genetics, vol.187, issue.4, pp.406-416, 1994.
DOI : 10.1007/BF00302252

D. Jones, J. Watkins, and S. K. Erickson, Taxonomically Significant Colour Changes in Brevibacterium linens Probably Associated with a Carotenoid-like Pigment, Journal of General Microbiology, vol.77, issue.1, pp.145-150, 1973.
DOI : 10.1099/00221287-77-1-145

B. H. Kim and A. J. Fulco, Induction by barbiturates of a cytochrome P-450-dependent fatty acid monooxygenase in Bacillus Megaterium: Relationship between barbiturate structure and inducer activity, Biochemical and Biophysical Research Communications, vol.116, issue.3, pp.843-850, 1983.
DOI : 10.1016/S0006-291X(83)80219-8

M. Klingenberg, Pigments of rat liver microsomes, Archives of Biochemistry and Biophysics, vol.75, issue.2, pp.376-386, 1958.
DOI : 10.1016/0003-9861(58)90436-3

W. Kohl, H. Achenbach, and H. Reichenbach, The pigments of Brevibacterium linens: Aromatic carotenoids, Phytochemistry, vol.22, issue.1, pp.207-210, 1983.
DOI : 10.1016/S0031-9422(00)80090-4

P. Krubasik and G. Sandmann, A carotenogenic gene cluster from Brevibacterium linens with novel lycopene cyclase genes involved in the synthesis of aromatic carotenoids, Molecular and General Genetics MGG, vol.263, issue.3, pp.423-432, 2000.
DOI : 10.1007/s004380051186

P. Krubasik and G. Sandmann, Molecular evolution of lycopene cyclases involved in the formation of carotenoids with ionone end groups, Biochemical Society Transactions, vol.28, issue.6, pp.806-810, 2000.
DOI : 10.1042/bst0280806

H. Krügel, P. Krubasik, K. Weber, H. P. Saluz, and G. Sandmann, Functional analysis of genes from Streptomyces griseus involved in the synthesis of isorenieratene, a carotenoid with aromatic end groups, revealed a novel type of carotenoid desaturase, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1439, issue.1, pp.57-64, 1999.
DOI : 10.1016/S1388-1981(99)00075-X

T. Kuzuyama, M. Takagi, S. Takahashi, and H. Seto, Cloning and Characterization of 1-Deoxy-D-Xylulose 5-Phosphate Synthase from Streptomyces sp. Strain CL190, Which Uses both the Mevalonate and Nonmevalonate Pathways for Isopentenyl Diphosphate Biosynthesis, Journal of Bacteriology, vol.182, issue.4, pp.891-897, 2000.
DOI : 10.1128/JB.182.4.891-897.2000

B. Laber, G. Usunow, E. Wiecko, W. Franke, H. Franke et al., Inhibition ofNarcissus pseudonarcissusPhytoene Desaturase by Herbicidal 3-Trifluoromethyl-1,1???-biphenyl Derivatives, Pesticide Biochemistry and Physiology, vol.63, issue.3, pp.173-184, 1999.
DOI : 10.1006/pest.1999.2401

D. Lagarde and W. Vermaas, The zeaxanthin biosynthesis enzyme bcarotene hydroxylase is involved in myxoxanthophyll synthesis in Synechocystis sp, PCC6803. FEBS Lett, vol.454, pp.247-251, 1999.

H. P. Lang, R. J. Cogdell, S. Takaichi, and N. Hunter, Complete DNA sequence, specific Tn5 insertion map, and gene assignment of the carotenoid biosynthesis pathway of Rhodobacter sphaeroides., Journal of Bacteriology, vol.177, issue.8, pp.2064-2073, 1995.
DOI : 10.1128/jb.177.8.2064-2073.1995

V. Leret, A. Trautwetter, A. Rince, and C. Blanco, ) pBLA8, from Brevibacterium linens, belongs to a gram-positive subfamily of ColE2-related plasmids. Microbiology, pp.2827-2836, 1998.

V. Levy-frebault and H. L. David, Mutations Affecting Pigment Synthesis in Mycobacterium aurum, Journal of General Microbiology, vol.115, issue.2, pp.317-323, 1979.
DOI : 10.1099/00221287-115-2-317

D. F. Lewis, Cytochromes P450: structure, function and mechanism., 348 pp, 1996.

D. F. Lewis and P. Hlavica, Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1460, issue.2-3, pp.353-374, 2000.
DOI : 10.1016/S0005-2728(00)00202-4

S. Liaaen-jensen and A. G. Andrewes, Microbial Carotenoids, Annual Review of Microbiology, vol.26, issue.1, pp.227-247, 1972.
DOI : 10.1146/annurev.mi.26.100172.001301

S. Liaaen-jensen and B. C. Weedon, The structure of leprotene, Die Naturwissenschaften, vol.30, issue.20, p.482, 1964.
DOI : 10.1007/BF00633101

H. K. Lichtenthaler, J. Schwender, A. Disch, and M. Rohmer, Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway, FEBS Letters, vol.400, issue.3, pp.271-274, 1997.
DOI : 10.1016/S0014-5793(96)01404-4

H. Linden, Carotenoid hydroxylase from Haematococcus pluvialis: cDNA sequence, regulation and functional complementation, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1446, issue.3, pp.203-212, 1999.
DOI : 10.1016/S0167-4781(99)00088-3

T. Lotan and J. Hirschberg, Cloning and expression in Escherichia coli of the gene encoding b-C-4-oxygenase, that converts ?-carotene to the ketocarotenoid canthaxanthin in Haematococcus pluvialis, FEBS Lett, vol.364, pp.125-128, 1995.

N. Misawa, M. Nakagawa, K. Kobayashi, S. Yamano, Y. Izawa et al., Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli., Journal of Bacteriology, vol.172, issue.12, pp.6704-6712, 1990.
DOI : 10.1128/jb.172.12.6704-6712.1990

N. Misawa, Y. Satomi, K. Kondo, A. Yokoyama, S. Kajiwara et al., Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level., Journal of Bacteriology, vol.177, issue.22, pp.6575-6584, 1995.
DOI : 10.1128/jb.177.22.6575-6584.1995

S. Modi, W. U. Primrose, J. M. Boyle, C. F. Gibson, L. Y. Lian et al., NMR Studies of Substrate Binding to Cytochrome P450 BM3: Comparisons to Cytochrome P450 cam, Biochemistry, vol.34, issue.28, pp.8982-8988, 1995.
DOI : 10.1021/bi00028a006

L. O. Narhi and A. J. Fulco, Phenobarbital Induction of a Soluble Cytochrome P-450-dependent Fatty Acid Monooxygenase in Bacillus megaterium, 1982.

D. Nebert and F. Gonzalez, P450 Genes: Structure, Evolution, and Regulation, Annual Review of Biochemistry, vol.56, issue.1, pp.945-993, 1987.
DOI : 10.1146/annurev.bi.56.070187.004501

D. R. Nelson, T. Kamataki, D. J. Waxman, F. P. Guengerich, R. W. Estabrook et al., The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature, DNA and Cell Biology, vol.12, issue.1, 1993.
DOI : 10.1089/dna.1993.12.1

U. Neudert, I. M. Martinez-ferez, P. D. Fraser, and G. Sandmann, Expression of an active phytoene synthase from Erwinia uredovora and biochemical properties of the enzyme, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1392, issue.1, pp.51-58, 1998.
DOI : 10.1016/S0005-2760(98)00017-4

J. A. Olson and N. I. Krinsky, Introduction: the colorful, fascinating world of the carotenoids: important physiologic modulators, FASEB J, vol.9, pp.1547-1550, 1995.

T. Omura and R. Sato, The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature, J. Biol. Chem, vol.239, pp.2370-2378, 1964.

P. R. Ortiz-de-montellano, Oxygen Activation and Transfer, pp.217-272, 1986.
DOI : 10.1007/978-1-4757-9939-2_7

P. R. Ortiz-de-montellano and M. A. Correia, Inhibition of Cytochrome P450 Enzymes, Cytochrome P450. Structure, mechanism, and biochemistry, pp.305-364, 1995.
DOI : 10.1007/978-1-4757-2391-5_9

K. E. Pallett, J. P. Little, M. Sheekey, and P. Veerasekaran, The Mode of Action of Isoxaflutole, Pesticide Biochemistry and Physiology, vol.62, issue.2, pp.113-124, 1998.
DOI : 10.1006/pest.1998.2378

L. Pasamontes, D. Hug, M. Tessier, H. Hohmann, J. Schierle et al., Isolation and characterization of the carotenoid biosynthesis genes of Flavobacterium sp. strain R1534, Gene, vol.185, issue.1, pp.35-41, 1997.
DOI : 10.1016/S0378-1119(96)00624-5

R. F. Peck, E. A. Johnson, and M. P. Krebs, Identification of a Lycopene ??-Cyclase Required for Bacteriorhodopsin Biogenesis in the Archaeon Halobacterium salinarum, Journal of Bacteriology, vol.184, issue.11, pp.2889-2897, 2002.
DOI : 10.1128/JB.184.11.2889-2897.2002

V. Pinta, S. Ouchane, M. Picaud, S. Takaichi, C. Astier et al., Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA, Archives of Microbiology, vol.403, issue.5, pp.354-362, 2003.
DOI : 10.1016/S0014-5793(97)00006-9

T. L. Poulos, B. C. Finzel, I. C. Gunsalus, G. C. Wagner, and J. Kraut, The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450, J. Biol. Chem, vol.260, pp.16122-16130, 1985.

W. Rademacher, : Effects on Gibberellin Biosynthesis and Other Metabolic Pathways, Annual Review of Plant Physiology and Plant Molecular Biology, vol.51, issue.1, pp.501-531, 2000.
DOI : 10.1146/annurev.arplant.51.1.501

W. Rademacher, H. Fritsch, J. E. Graebe, H. Sauter, and J. Jung, Tetcyclacis and triazole-type plant growth retardants: Their influence on the biosynthesis of gibberellins and other metabolic processes, Pesticide Science, vol.50, issue.Suppl. 1, pp.241-252, 1987.
DOI : 10.1002/ps.2780210402

A. Raisig and G. Sandmann, Functional properties of diapophytoene and related desaturases of C30 and C40 carotenoid biosynthetic pathways, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1533, issue.2, pp.164-170, 2001.
DOI : 10.1016/S1388-1981(01)00154-8

E. D. Ritter and A. E. Purcell, CAROTENOID ANALYTICAL METHODS, pp.815-923, 1981.
DOI : 10.1016/B978-0-12-082850-0.50017-2

F. Rohdich, S. Hecht, K. Gärtner, P. Adam, C. Krieger et al., Studies on the nonmevalonate terpene biosynthetic pathway: Metabolic role of IspH (LytB) protein, Proceedings of the National Academy of Sciences, vol.99, issue.3, pp.1158-1163, 2002.
DOI : 10.1073/pnas.032658999

M. Rohmer, A Mevalonate-independent Route to Isopentenyl Diphosphate, pp.45-67, 1999.
DOI : 10.1016/B978-0-08-091283-7.00036-9

M. Rohmer, M. Knani, P. Simonin, B. Sutter, and H. Sahm, Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate, Biochemical Journal, vol.295, issue.2, pp.517-524, 1993.
DOI : 10.1042/bj2950517

M. Rohmer, M. Seemann, S. Horbach, S. Bringer-meyer, and H. Sahm, Glyceraldehyde 3-Phosphate and Pyruvate as Precursors of Isoprenic Units in an Alternative Non-mevalonate Pathway for Terpenoid Biosynthesis, Journal of the American Chemical Society, vol.118, issue.11, pp.2564-2566, 1996.
DOI : 10.1021/ja9538344

M. Rossi, Structural studies of metyrapone: a potent inhibitor of cytochrome P-450, Journal of Medicinal Chemistry, vol.26, issue.9, pp.1246-1252, 1983.
DOI : 10.1021/jm00363a008

G. Sandmann, Carotenoid Biosynthesis and Biotechnological Application, Archives of Biochemistry and Biophysics, vol.385, issue.1, pp.4-12, 2001.
DOI : 10.1006/abbi.2000.2170

G. Sandmann and P. M. Bramley, The in vitro biosynthesis of ??-cryptoxanthin and related xanthophylls with Aphanocapsa membranes, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.843, issue.1-2, pp.73-77, 1985.
DOI : 10.1016/0304-4165(85)90051-0

G. Sandmann, W. S. Woods, and R. W. Tuveson, Identification of carotenoids in Erwinia herbicola and in a transformed Escherichia coli strain, FEMS Microbiology Letters, vol.71, issue.1-2, pp.77-82, 1990.
DOI : 10.1111/j.1574-6968.1990.tb03801.x

J. B. Schenkman and I. Lngela, Spectral Analyses of Cytochromes P450, pp.25-34, 1998.

C. Schneider, P. Böger, and G. Sandmann, Phytoene Desaturase: Heterologous Expression in an Active State, Purification, and Biochemical Properties, Protein Expression and Purification, vol.10, issue.2, pp.175-179, 1997.
DOI : 10.1006/prep.1997.0730

B. Schoefs, N. E. Rmiki, J. Rachadi, and Y. Lemoine, requires a cytochrome P450 hydroxylase and an active synthesis of fatty acids, FEBS Letters, vol.2, issue.3, pp.125-128, 2001.
DOI : 10.1016/S0014-5793(01)02596-0

G. Schumann, H. Nürnberger, G. Sandmann, and H. Krügel, Activation and analysis of cryptic crt genes for carotenoid biosynthesis from Streptomyces griseus, Mol. Gen. Genet, vol.252, pp.658-666, 1996.

P. A. Scolnik, M. A. Walker, and B. L. Marrs, Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata, J. Biol. Chem, vol.255, pp.2427-2432, 1980.

M. D. Segall, An ab Initio Study of Biological Systems, 1997.

H. Shimizu, S. Y. Park, D. S. Lee, H. Shoun, and Y. Shiro, Crystal structures of cytochrome P450nor and its mutants (Ser286???Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s, Journal of Inorganic Biochemistry, vol.81, issue.3, pp.191-205, 2000.
DOI : 10.1016/S0162-0134(00)00103-3

T. Shimizu, T. Tateishi, M. Hatano, and Y. Fujii-kuriyama, Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by sitedirected mutagenesis, J. Biol. Chem, vol.266, pp.3372-3375, 1990.

C. Sieiro, M. Poza, T. D. Miguel, and T. G. Villa, Genetic basis of microbial carotenogenesis, Int. Microbiol, vol.6, pp.11-16, 2003.

A. Souter, K. J. Mclean, W. E. Smith, and A. W. Munro, The genome sequence ofMycobacterium tuberculosis reveals cytochromes P450 as novel anti-TB drug targets, Journal of Chemical Technology & Biotechnology, vol.6, issue.10, pp.933-941, 2000.
DOI : 10.1002/1097-4660(200010)75:10<933::AID-JCTB301>3.0.CO;2-C

P. Stickforth, S. Steiger, W. R. Hess, and G. Sandmann, A novel type of lycopene ??-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4, Archives of Microbiology, vol.262, issue.6, pp.409-415, 2003.
DOI : 10.1002/1439-7633(20020703)3:7<629::AID-CBIC629>3.0.CO;2-5

O. Straub, Key to carotenoids, 1987.
DOI : 10.1007/978-3-0348-5065-0

L. Tian and D. Dellapenna, Progress in understanding the origin and functions of carotenoid hydroxylases in plants, Archives of Biochemistry and Biophysics, vol.430, issue.1, pp.22-29, 2004.
DOI : 10.1016/j.abb.2004.02.003

L. Tian, M. Magallanes-lundback, V. Musetti, and D. Dellapenna, Functional Analysis of ??- and ??-Ring Carotenoid Hydroxylases in Arabidopsis, THE PLANT CELL ONLINE, vol.15, issue.>6, pp.1320-1332, 2003.
DOI : 10.1105/tpc.011403

L. Tian, V. Musetti, J. Kim, M. Magallanes-lundback, and D. Dellapenna, The Arabidopsis LUT1 locus encodes a member of the cytochrome P450 family that is required for carotenoid ??-ring hydroxylation activity, Proceedings of the National Academy of Sciences, vol.101, issue.1, pp.402-407, 2004.
DOI : 10.1073/pnas.2237237100

I. Tomasi, I. Artaud, Y. Bertheau, and D. Mansuy, Metabolism of polychlorinated phenols by Pseudomonas cepacia AC1100: determination of the first two steps and specific inhibitory effect of methimazole., Journal of Bacteriology, vol.177, issue.2, pp.307-311, 1995.
DOI : 10.1128/jb.177.2.307-311.1995

M. Tsukamura, Adansonian Classification of Mycobacteria, Journal of General Microbiology, vol.45, issue.2, pp.253-273, 1966.
DOI : 10.1099/00221287-45-2-253

D. Umeno, A. V. Tobias, and F. H. Arnold, Evolution of the C30 Carotenoid Synthase CrtM for Function in a C40 Pathway, Journal of Bacteriology, vol.184, issue.23, pp.6690-6699, 2002.
DOI : 10.1128/JB.184.23.6690-6699.2002

A. R. Valla, D. L. Cartier, B. G. Valla, R. Y. Guillou, Z. R. Andriamialisoa et al., New Synthesis of Natural Carotene Isorenieratene (??,??-Carotene) and its 3,3???-Dimethoxy Analogue, Helvetica Chimica Acta, vol.86, issue.10, pp.3314-3319, 2003.
DOI : 10.1002/hlca.200390273

A. Velayos, A. P. Eslava, and E. A. Iturriaga, A bifunctional enzyme with lycopene cyclase and phytoene synthase activities is encoded by the carRP gene of Mucor circinelloides, European Journal of Biochemistry, vol.13, issue.17, pp.5509-5519, 2000.
DOI : 10.1046/j.1432-1327.2000.01612.x

J. C. Verdoes, K. P. Krubasik, G. Sandmann, and A. J. Van-ooyen, Isolation and functional characterisation of a novel type of carotenoid biosynthetic gene from Xanthophyllomyces dendrorhous, Molecular and General Genetics MGG, vol.262, issue.3, pp.453-461, 1999.
DOI : 10.1007/s004380051105

J. C. Verdoes, G. Sandmann, H. Visser, M. Diaz, M. Van-mossel et al., Metabolic Engineering of the Carotenoid Biosynthetic Pathway in the Yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma), Applied and Environmental Microbiology, vol.69, issue.7, pp.3728-3738, 2003.
DOI : 10.1128/AEM.69.7.3728-3738.2003

H. Visser, A. J. Van-ooyen, and J. C. Verdoes, Metabolic engineering of the astaxanthin-biosynthetic pathway of, FEMS Yeast Research, vol.4, issue.3, pp.221-231, 2003.
DOI : 10.1016/S1567-1356(03)00158-2

M. Viveiros, P. Krubasik, G. Sandmann, and M. Houssaini-iraqui, A+, FEMS Microbiology Letters, vol.187, issue.1, pp.95-101, 2000.
DOI : 10.1111/j.1574-6968.2000.tb09143.x
URL : https://hal.archives-ouvertes.fr/hal-00640445

D. Werck-reichhart and R. Feyereisen, Cytochromes P450, The Arabidopsis Book, vol.1, pp.3003-3009, 2000.
DOI : 10.1199/tab.0028
URL : https://hal.archives-ouvertes.fr/hal-00123631

B. Wieland, C. Feil, E. Gloria-maercker, G. Thumm, M. Lechner et al., Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus., Journal of Bacteriology, vol.176, issue.24, pp.7719-7726, 1994.
DOI : 10.1128/jb.176.24.7719-7726.1994

M. Yamaguchi, On Carotenoids of a Sponge ??? Reniera japonica ???, Bulletin of the Chemical Society of Japan, vol.30, issue.2, pp.111-114, 1957.
DOI : 10.1246/bcsj.30.111

A. A. Yeliseev and S. Kaplan, O is a source of oxygen for the 1-methoxy group of spheroidene but not for the 2-oxo group of spheroidenone, FEBS Letters, vol.403, issue.1, pp.10-14, 1997.
DOI : 10.1016/S0014-5793(97)00006-9

A. Yokoyama, Y. Shizuri, T. Hoshino, and G. Sandmann, Thermocryptoxanthins: novel intermediates in the carotenoid biosynthetic pathway of Thermus thermophilus, Archives of Microbiology, vol.165, issue.5, pp.342-345, 1996.
DOI : 10.1007/s002030050336

M. H. Zwietering, I. Jongenburger, F. M. Rombouts, and K. Van-'t-riet, Modeling of the Bacterial Growth Curve, Appl. Environ. Microbiol, vol.56, pp.1875-1881, 1990.