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Theses

Imagerie Cardiaque Multimodalités 2D et 3D :
application à la Coronarographie/Tomoscintigraphie/TEP-CT

Abstract : Coronarography and tomoscintigraphy (SPECT, Single Photon Emission Tomography) are two imaging
techniques used standardly for the diagnosis of cardiovascular diseases. The first modality consists of X-ray
image sequences visualizing each, in a same plane, the coronary arteries located on the front and the back side
of the heart. The X-ray images give anatomical information relating to the arterial tree and highlight eventual
artery narrowings (stenoses). The SPECT modality (nuclear imaging) provide a 3D representation of the
myocardial volume perfusion. This functional information authorizes the visualization of myocardial regions
suffering from irrigation defaults. The aim of the presented work is to superimpose (in the 3D space) the
functional and anatomical information in order to establish the visual link between arterial lesions and their
consequence in terms of irrigation defaults. In the 3D representation chosen to facilitate the diagnosis, the
structure of a schematic arterial tree and the stenoses are placed onto the perfusion volume. The initial data
consist of a list of points representative for the arterial tree (start and end points of arterial segments,
bifurcations, stenoses, etc) and marked by coronarographists on the X-ray images of the different incidences.
The perfusion volume is then projected under the incidences of the coronarographic images. A registration
algorithm superimposing the X-ray images and the corresponding SPECT projections provides the parameters
of the geometrical transformations bringing the points marked in the X rays images in equivalent positions in
the 2D SPECT images. A 3D reconstruction algorithm is then used to place the arterial points and the stenoses
on the perfusion volume and build a schematic tree acting as landmark for the clinician. A 28 patient database
was used to realize 40 3D superimposition of anatomo-functional data. These reconstructions have shown that
the 3D representation is precise enough for the establishment of the visual relationship between stenoses and
perfusion defaults. Our 3D superimposition algorithms were then be completed in order to replace the SPECT
modality by data of the PET/CT (Positron Emission Tomography/Computed Tomography) bimodal
examination. The data of a clinical trimodal PET/CT/coronarography case have been used to evaluate the
adequacy of our algorithms to novel imaging modalities.
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https://tel.archives-ouvertes.fr/tel-00118991
Contributor : Didier Wolf <>
Submitted on : Thursday, December 7, 2006 - 1:48:44 PM
Last modification on : Friday, October 23, 2020 - 8:38:02 AM
Long-term archiving on: : Tuesday, April 6, 2010 - 8:38:37 PM

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  • HAL Id : tel-00118991, version 1

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Citation

Juan Lopez-Hernandez. Imagerie Cardiaque Multimodalités 2D et 3D :
application à la Coronarographie/Tomoscintigraphie/TEP-CT. Traitement du signal et de l'image [eess.SP]. Institut National Polytechnique de Lorraine - INPL, 2006. Français. ⟨tel-00118991⟩

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