. Le-modèle-de-prolifération-virale-utilisé-est-le-système-d-'edo-s-v3, ), et le modèle d'activation lymphocytaire T est celui dit, pp.164-92

. La-prolifération-virale-peut-durer, en réalité (clinique), plusieurs jours (par exemple 5 à 6 jours pour un rhume) La réponse immunitaire n'est généralement apparente que

. Ici, le pas de temps de l'algorithme de couplage (?t) a été fixé à 15 minutes. Nous avons choisi d'augmenter ce pas de temps par

. La-deuxième-raison-de-ce-choix, Plus le pas de temps (?t) sera petit, et plus le temps de calcul sera long. Dans notre cas, avec ce second jeu de paramètres

. La-figure-15, 3 présente également les quantités uCell, iCell 0 , iCell 1 , iCell 2 et V ir obtenues avec le couplage des deux modèles (prolifération virale et activation du lymphocyte T) La figure 15.4 indique le nombre de cellules filles du lymphocyte T spécifique de l'antigène viral, sur le lieu de l'infection, pour la période de temps s

. Dans-ce-cas,-la-durée-de-la, maladie" est aussi d'environ 50 heures Et les lymphocytes T cytotoxiques se trouvent sur le lieu de l'infection environ 49,5 heures (1, 782.10 5 secondes) après l'apparition du virus

. Dans-cette-annexe, nous cherchons les états stationnaires des modèles d'activation du lymphocyte T Cette recherche nous a conduits, p.92

L. Modèles, complet" et "simplifié") proposés pour l'activation du lymphocyte T étant non-linéaires, il est difficile d'obtenir pour chaque concentration stationnaire une expression simple

. Dans-cette-annexe, nous cherchons à explorer les modèles d'infection virale, S v1

L. Nous-faisons-ici-l-'hypothèse-que-le-paramètre, spécifiques du virus, présents sur le lieu de l'infection) est une constante, 2001.

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